Motif ID: PAX5.p2

Z-value: 1.611


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
PAX5chr9_-_37034358-0.452.3e-02Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_80679897 4.733 NM_001040708
NM_012258
 HEY1

hairy/enhancer-of-split related with YRPW motif 1

chr5_+_118604504 4.239 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr15_+_67358161 4.175 SMAD3
SMAD family member 3
chr4_+_103422553 3.836 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr16_+_11762235 3.522 NM_003498
 SNN
stannin
chr5_+_118604417 3.414 NM_001077654
 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr15_+_67358194 3.285 NM_005902
 SMAD3
SMAD family member 3
chr21_+_46293925 3.204


chr4_+_103422822 2.999 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr4_+_103422730 2.998 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr4_+_103422479 2.941 NM_001165412
NM_003998
 NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

chr6_+_37137882 2.759 NM_001243186
NM_002648
 PIM1

pim-1 oncogene

chr9_-_123691442 2.591 NM_001190945
 TRAF1
TNF receptor-associated factor 1
chr6_+_14117857 2.499 NM_001040280
NM_004233
 CD83

CD83 molecule

chr6_+_14118002 2.467 CD83
CD83 molecule
chr5_-_131826426 2.414 NM_002198
 IRF1
interferon regulatory factor 1
chr6_-_109804322 2.362 ZBTB24
zinc finger and BTB domain containing 24
chr21_+_33784751 2.344 NM_058187
 C21orf63
chromosome 21 open reading frame 63
chr6_-_160114186 2.309 SOD2
superoxide dismutase 2, mitochondrial
chr18_+_77155927 2.296 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 119 entries
enrichment   p-value GO term description
1.57 1.04e-02 GO:0051493 regulation of cytoskeleton organization
1.52 4.29e-02 GO:0032869 cellular response to insulin stimulus
1.48 1.81e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.43 4.48e-02 GO:0009166 nucleotide catabolic process
1.42 1.76e-03 GO:0090066 regulation of anatomical structure size
1.41 1.18e-02 GO:0009150 purine ribonucleotide metabolic process
1.41 1.37e-02 GO:0006511 ubiquitin-dependent protein catabolic process
1.40 6.65e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.40 1.23e-02 GO:0009259 ribonucleotide metabolic process
1.40 1.91e-02 GO:0033043 regulation of organelle organization
1.40 2.35e-02 GO:0043632 modification-dependent macromolecule catabolic process
1.40 4.08e-02 GO:0009141 nucleoside triphosphate metabolic process
1.39 1.70e-02 GO:0044257 cellular protein catabolic process
1.39 2.48e-02 GO:0032535 regulation of cellular component size
1.39 2.63e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.39 2.71e-02 GO:0019941 modification-dependent protein catabolic process
1.38 1.77e-02 GO:0030163 protein catabolic process
1.37 1.42e-06 GO:0012501 programmed cell death
1.37 5.18e-05 GO:0010629 negative regulation of gene expression
1.37 1.80e-02 GO:0006163 purine nucleotide metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 44 entries
enrichment   p-value GO term description
1.70 1.18e-02 GO:0042470 melanosome
1.70 1.18e-02 GO:0048770 pigment granule
1.41 9.82e-04 GO:0005815 microtubule organizing center
1.38 1.08e-04 GO:0005768 endosome
1.38 1.54e-02 GO:0015629 actin cytoskeleton
1.37 1.61e-04 GO:0000139 Golgi membrane
1.35 1.32e-06 GO:0031967 organelle envelope
1.34 1.54e-06 GO:0031975 envelope
1.34 1.15e-03 GO:0005740 mitochondrial envelope
1.33 1.04e-04 GO:0044431 Golgi apparatus part
1.31 4.05e-18 GO:0005829 cytosol
1.31 1.29e-02 GO:0031966 mitochondrial membrane
1.29 1.60e-06 GO:0005794 Golgi apparatus
1.29 4.30e-04 GO:0015630 microtubule cytoskeleton
1.27 2.22e-03 GO:0044429 mitochondrial part
1.26 5.39e-09 GO:0012505 endomembrane system
1.26 1.55e-03 GO:0031982 vesicle
1.25 2.89e-03 GO:0031410 cytoplasmic vesicle
1.24 2.99e-11 GO:0031090 organelle membrane
1.24 1.53e-02 GO:0031988 membrane-bounded vesicle

Gene overrepresentation in function category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
1.67 6.40e-03 GO:0017124 SH3 domain binding
1.54 3.08e-02 GO:0003714 transcription corepressor activity
1.45 2.55e-03 GO:0016881 acid-amino acid ligase activity
1.44 1.29e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.43 1.99e-02 GO:0019787 small conjugating protein ligase activity
1.37 4.43e-04 GO:0019904 protein domain specific binding
1.36 5.53e-03 GO:0000988 protein binding transcription factor activity
1.36 5.53e-03 GO:0000989 transcription factor binding transcription factor activity
1.36 7.64e-03 GO:0003712 transcription cofactor activity
1.30 1.16e-04 GO:0019899 enzyme binding
1.24 1.73e-02 GO:0042802 identical protein binding
1.20 2.13e-07 GO:0000166 nucleotide binding
1.19 3.27e-05 GO:0017076 purine nucleotide binding
1.19 3.96e-05 GO:0032553 ribonucleotide binding
1.19 3.96e-05 GO:0032555 purine ribonucleotide binding
1.18 1.03e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.17 1.69e-29 GO:0005515 protein binding
1.17 9.63e-03 GO:0030554 adenyl nucleotide binding
1.17 1.36e-02 GO:0032559 adenyl ribonucleotide binding
1.16 3.49e-02 GO:0005524 ATP binding