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Motif ID: PAX6.p2

Z-value: 0.259

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_16059817	0.268	NM_001004465	OR10H4	olfactory receptor, family 10, subfamily H, member 4
chr3_-_151102536	0.260	NM_022788	P2RY12	purinergic receptor P2Y, G-protein coupled, 12
chr9_-_16870664	0.203		BNC2	basonuclin 2
chr16_-_48266181	0.196	NM_033151	ABCC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr5_-_94224601	0.156		MCTP1	multiple C2 domains, transmembrane 1
chrX_-_130423387	0.148	NM_001170961 NM_001170962 NM_001555 NM_205833	IGSF1	immunoglobulin superfamily, member 1
chr12_-_71031174	0.131	NM_001109754	PTPRB	protein tyrosine phosphatase, receptor type, B
chr22_+_39745757	0.112	NM_004711 NM_145731	SYNGR1	synaptogyrin 1
chr15_-_50405512	0.109		ATP8B4	ATPase, class I, type 8B, member 4
chr5_-_141338626	0.104	NM_016580	PCDH12	protocadherin 12
chr7_+_80267972	0.104		CD36	CD36 molecule (thrombospondin receptor)
chr1_+_114522029	0.097	NM_020190	OLFML3	olfactomedin-like 3
chr5_+_57787260	0.089	NM_152687	GAPT	GRB2-binding adaptor protein, transmembrane
chr1_+_84767288	0.083	NM_001134663	SAMD13	sterile alpha motif domain containing 13
chr4_+_187148624	0.078	NM_000892	KLKB1	kallikrein B, plasma (Fletcher factor) 1
chr3_-_58652469	0.075	NM_138805	FAM3D	family with sequence similarity 3, member D
chr12_+_56915587	0.074	NM_002898	RBMS2	RNA binding motif, single stranded interacting protein 2
chr16_+_72088507	0.072	NM_001126102 NM_005143	HP	haptoglobin
chr18_+_61420276	0.072	NM_001040147	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr18_-_45663667	0.066	NM_001039360	ZBTB7C	zinc finger and BTB domain containing 7C
chr3_-_149051258	0.061	NM_001184723 NM_138786	TM4SF18	transmembrane 4 L six family member 18
chr7_-_73123431	0.061		STX1A	syntaxin 1A (brain)
chr3_+_111717585	0.060	NM_001008272 NM_013259	TAGLN3	transgelin 3
chr7_+_80267922	0.059		CD36	CD36 molecule (thrombospondin receptor)
chr11_+_111789658	0.058		C11orf52	chromosome 11 open reading frame 52
chr6_-_10412606	0.058	NM_001032280	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr4_+_130017281	0.054	NM_001099783	C4orf33	chromosome 4 open reading frame 33
chr8_+_39792473	0.054	NM_194294	IDO2	indoleamine 2,3-dioxygenase 2
chr12_+_18414473	0.051	NM_004570	PIK3C2G	phosphoinositide-3-kinase, class 2, gamma polypeptide
chrX_+_148769902	0.050	NM_001011544	MAGEA11	melanoma antigen family A, 11
chr7_-_108142934	0.048		PNPLA8	patatin-like phospholipase domain containing 8
chr5_+_85913755	0.048		COX7C	cytochrome c oxidase subunit VIIc
chr17_+_58499854	0.047	NM_181707	C17orf64	chromosome 17 open reading frame 64
chr5_+_79615789	0.046	NM_032567	SPZ1	spermatogenic leucine zipper 1
chr2_-_133539627	0.046		NCKAP5	NCK-associated protein 5
chr12_-_7848324	0.046	NM_020634	GDF3	growth differentiation factor 3
chr2_+_179184970	0.046	NM_145739	OSBPL6	oxysterol binding protein-like 6
chrX_-_130423199	0.046		IGSF1	immunoglobulin superfamily, member 1
chr7_+_22766765	0.045	NM_000600	IL6	interleukin 6 (interferon, beta 2)
chr2_-_163008913	0.045	NM_002054	GCG	glucagon
chr7_+_155250705	0.044	NM_001427	EN2	engrailed homeobox 2
chr5_+_147691988	0.044	NM_032566	SPINK7	serine peptidase inhibitor, Kazal type 7 (putative)
chr11_+_844445	0.043	NM_001025237	TSPAN4	tetraspanin 4
chr10_+_114043413	0.043	NM_058222	TECTB	tectorin beta
chr4_+_70861647	0.041	NM_001009181 NM_003154	STATH	statherin
chr6_+_14117486	0.039	NM_001251901	CD83	CD83 molecule
chr12_+_10460416	0.039	NM_002262 NM_007334	KLRD1	killer cell lectin-like receptor subfamily D, member 1
chr3_-_128186090	0.039	NM_153330	DNAJB8	DnaJ (Hsp40) homolog, subfamily B, member 8
chr6_+_147527102	0.038		STXBP5	syntaxin binding protein 5 (tomosyn)
chrX_-_65259839	0.038	NM_001100431 NM_001184830 NM_001184831 NM_007268	VSIG4	V-set and immunoglobulin domain containing 4
chr6_-_64029847	0.037	NM_001143940 NM_016571	LGSN	lengsin, lens protein with glutamine synthetase domain
chr1_-_6580068	0.037	NM_198681	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr5_-_142077508	0.036	NM_001144934 NM_001144935	FGF1	fibroblast growth factor 1 (acidic)
chr17_+_9745847	0.036		GLP2R	glucagon-like peptide 2 receptor
chr6_+_42896859	0.036	NM_006586	CNPY3	canopy 3 homolog (zebrafish)
chr5_-_135231504	0.036	NM_000590	IL9	interleukin 9
chr2_+_170366211	0.035	NM_006063	KBTBD10	kelch repeat and BTB (POZ) domain containing 10
chr5_+_140254930	0.033	NM_018903 NM_031864	PCDHA12	protocadherin alpha 12
chr18_+_18822168	0.033	NM_001142966	GREB1L	growth regulation by estrogen in breast cancer-like
chr5_+_175223519	0.033	NM_006650	CPLX2	complexin 2
chr11_+_111789600	0.032	NM_080659	C11orf52	chromosome 11 open reading frame 52
chr12_-_70093064	0.031	NM_032735	BEST3	bestrophin 3
chr19_+_15852200	0.031	NM_013938	OR10H3	olfactory receptor, family 10, subfamily H, member 3
chr11_+_117947785	0.031		TMPRSS4	transmembrane protease, serine 4
chr10_+_124030820	0.030	NM_144587	BTBD16	BTB (POZ) domain containing 16
chrX_+_103357106	0.030	NM_001143978	ZCCHC18	zinc finger, CCHC domain containing 18
chr9_-_140142165	0.030	NM_001001710	FAM166A	family with sequence similarity 166, member A
chr1_-_12908141	0.028	NM_001146181	HNRNPCL1 LOC649330	heterogeneous nuclear ribonucleoprotein C-like 1 heterogeneous nuclear ribonucleoprotein C-like
chr8_-_93111915	0.028	NM_001198628	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_+_124048396	0.027		GSN	gelsolin
chr16_+_70147528	0.027	NM_017990	PDPR	pyruvate dehydrogenase phosphatase regulatory subunit
chr1_-_226926875	0.026	NM_002221	ITPKB	inositol-trisphosphate 3-kinase B
chr11_+_76883823	0.026		MYO7A	myosin VIIA
chr12_+_8666135	0.025	NM_080387	CLEC4D	C-type lectin domain family 4, member D
chr6_-_76203256	0.025	NM_015687	FILIP1	filamin A interacting protein 1
chrX_+_50653734	0.024	NM_005448	BMP15	bone morphogenetic protein 15
chr7_+_110731061	0.024	NM_001099658 NM_001099660 NM_018334	LRRN3	leucine rich repeat neuronal 3
chr16_+_53479685	0.024		RBL2	retinoblastoma-like 2 (p130)
chr4_+_100495972	0.023		MTTP	microsomal triglyceride transfer protein
chr4_-_68749698	0.022	NM_004262	TMPRSS11D	transmembrane protease, serine 11D
chr11_+_117947726	0.021	NM_001083947 NM_001173551 NM_001173552 NM_019894	TMPRSS4	transmembrane protease, serine 4
chr2_-_200325200	0.021		SATB2	SATB homeobox 2
chrX_+_144908927	0.021	NM_004709	CXorf1	chromosome X open reading frame 1
chr10_+_129845806	0.021	NM_130435	PTPRE	protein tyrosine phosphatase, receptor type, E
chr1_+_159409511	0.020	NM_012351	OR10J1	olfactory receptor, family 10, subfamily J, member 1
chr7_+_80275634	0.020	NM_001127443 NM_001127444	CD36	CD36 molecule (thrombospondin receptor)
chr21_-_39870303	0.020	NM_001136155 NM_182918	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr3_+_25470067	0.020		RARB	retinoic acid receptor, beta
chr5_+_143191725	0.020	NM_021182	HMHB1	histocompatibility (minor) HB-1
chr1_+_87380437	0.020		HS2ST1	heparan sulfate 2-O-sulfotransferase 1
chr15_+_45544427	0.019	NM_004212	SLC28A2	solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
chrX_-_13835213	0.019		GPM6B	glycoprotein M6B
chrX_-_53461291	0.018	NM_001037811 NM_004493	HSD17B10	hydroxysteroid (17-beta) dehydrogenase 10
chr5_+_55147206	0.018	NM_001242637 NM_001242638 NM_139017	IL31RA	interleukin 31 receptor A
chr17_-_39023461	0.018	NM_000223	KRT12	keratin 12
chr10_-_46030798	0.017	NM_001002266	MARCH8	membrane-associated ring finger (C3HC4) 8
chr3_+_108015392	0.017		HHLA2	HERV-H LTR-associating 2
chr10_-_79628870	0.016		DLG5	discs, large homolog 5 (Drosophila)
chr12_-_45269340	0.015	NM_001145109	NELL2	NEL-like 2 (chicken)
chr1_+_209878135	0.015	NM_005525	HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1
chr8_+_124194873	0.015		FAM83A	family with sequence similarity 83, member A
chr4_-_65275000	0.015	NM_001010874	TECRL	trans-2,3-enoyl-CoA reductase-like
chr6_-_48078909	0.014		C6orf138	chromosome 6 open reading frame 138
chr5_+_140174443	0.014	NM_018905 NM_031495	PCDHA2	protocadherin alpha 2
chr3_-_147123306	0.014	NM_001168379	ZIC4	Zic family member 4
chr19_-_14992166	0.013	NM_030901	OR7A17	olfactory receptor, family 7, subfamily A, member 17
chr2_-_162931051	0.013	NM_001935	DPP4	dipeptidyl-peptidase 4
chr3_+_136649316	0.013	NM_001190796	NCK1	NCK adaptor protein 1
chr3_+_49506079	0.013	NM_001177643	DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr4_+_56261763	0.012
chr19_-_14910947	0.012	NM_198944	OR7C1	olfactory receptor, family 7, subfamily C, member 1
chr2_-_99279935	0.012	NM_001160154	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr1_+_47533046	0.012	NM_178134	CYP4Z1	cytochrome P450, family 4, subfamily Z, polypeptide 1
chr20_+_4702499	0.012	NM_012409	PRND	prion protein 2 (dublet)
chr5_+_152870083	0.012	NM_000827 NM_001114183	GRIA1	glutamate receptor, ionotropic, AMPA 1
chr5_+_140734767	0.011	NM_018917 NM_032053	PCDHGA4	protocadherin gamma subfamily A, 4
chr19_-_51961648	0.010	NM_014442	SIGLEC8	sialic acid binding Ig-like lectin 8
chr12_-_133215775	0.010		POLE	polymerase (DNA directed), epsilon
chr9_-_85946875	0.010	NM_001244961	FRMD3	FERM domain containing 3
chr7_+_73275488	0.009	NM_182504	WBSCR28	Williams-Beuren syndrome chromosome region 28
chr2_+_115822246	0.009	NM_001178037	DPP10	dipeptidyl-peptidase 10 (non-functional)
chr10_+_118350470	0.009	NM_006229	PNLIPRP1	pancreatic lipase-related protein 1
chr13_-_110802708	0.008		COL4A1	collagen, type IV, alpha 1
chr1_-_87379808	0.008		SEP15	15 kDa selenoprotein
chr17_-_34503914	0.008	NM_001001417	TBC1D3B TBC1D3C TBC1D3G	TBC1 domain family, member 3B TBC1 domain family, member 3C TBC1 domain family, member 3G
chr17_-_36348585	0.008	NM_001123391 NM_032258	TBC1D3C TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3 TBC1 domain family, member 3F
chrX_-_13835187	0.008		GPM6B	glycoprotein M6B
chr21_+_39644428	0.007	NM_170737	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr1_-_87379784	0.007		SEP15	15 kDa selenoprotein
chr2_-_158182154	0.007	NM_020711	ERMN	ermin, ERM-like protein
chr17_-_34756980	0.007	NM_001123392	TBC1D3C TBC1D3G TBC1D3 TBC1D3H	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3H
chr7_+_80267782	0.007	NM_000072 NM_001001548	CD36	CD36 molecule (thrombospondin receptor)
chr6_-_75994631	0.007	NM_001143958 NM_018247	TMEM30A	transmembrane protein 30A
chr10_-_94257470	0.007	NM_001165946	IDE	insulin-degrading enzyme
chr10_+_83637442	0.007	NM_001165973	NRG3	neuregulin 3
chr12_-_121792011	0.007	NM_001137559	ANAPC5	anaphase promoting complex subunit 5
chr16_-_51184507	0.006	NM_001127892	SALL1	sal-like 1 (Drosophila)
chr3_+_133118789	0.006	NM_003571	BFSP2	beaded filament structural protein 2, phakinin
chr1_-_31345361	0.006		SDC3	syndecan 3
chr17_+_36283959	0.006	NM_001123391 NM_032258	TBC1D3C TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3 TBC1 domain family, member 3F
chrY_-_27198250	0.006	NM_001002760 NM_001002761 NM_004678	BPY2B BPY2C BPY2	basic charge, Y-linked, 2B basic charge, Y-linked, 2C basic charge, Y-linked, 2
chr1_-_108786663	0.006	NM_001143989	NBPF4 NBPF6	neuroblastoma breakpoint family, member 4 neuroblastoma breakpoint family, member 6
chr17_-_34591958	0.006	NM_001001418	TBC1D3C TBC1D3G	TBC1 domain family, member 3C TBC1 domain family, member 3G
chr14_+_102276125	0.005	NM_002719 NM_178586 NM_178587	PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chr6_+_167704802	0.005	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chr19_+_7968820	0.005		MAP2K7	mitogen-activated protein kinase kinase 7
chr8_-_7673137	0.005	NM_001037668 NM_001040705	DEFB107A DEFB107B	defensin, beta 107A defensin, beta 107B
chr8_+_7705401	0.005	NM_058203 NM_001081552	SPAG11B SPAG11A	sperm associated antigen 11B sperm associated antigen 11A
chrY_+_25130409	0.005	NM_001002760 NM_001002761 NM_004678	BPY2B BPY2C BPY2	basic charge, Y-linked, 2B basic charge, Y-linked, 2C basic charge, Y-linked, 2
chrY_+_26764150	0.005	NM_001002760 NM_001002761 NM_004678	BPY2B BPY2C BPY2	basic charge, Y-linked, 2B basic charge, Y-linked, 2C basic charge, Y-linked, 2
chr9_-_14779530	0.005	NM_001177704	FREM1	FRAS1 related extracellular matrix 1
chrX_-_13835313	0.005	NM_001001995 NM_001001996 NM_005278	GPM6B	glycoprotein M6B
chr20_-_1309809	0.004	NM_080489	SDCBP2	syndecan binding protein (syntenin) 2
chr11_-_40315663	0.004	NM_020929	LRRC4C	leucine rich repeat containing 4C
chr1_+_158901336	0.004	NM_152501 NM_198928 NM_198929 NM_198930	PYHIN1	pyrin and HIN domain family, member 1
chr1_+_87380317	0.004	NM_001134492 NM_012262	HS2ST1	heparan sulfate 2-O-sulfotransferase 1
chr17_-_36956145	0.004	NM_003559	PIP4K2B	phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chrX_-_106449543	0.004	NM_017681	NUP62CL	nucleoporin 62kDa C-terminal like
chr3_-_195310770	0.004		APOD	apolipoprotein D
chr20_+_32250089	0.003	NM_080825	C20orf144	chromosome 20 open reading frame 144
chr2_-_200213802	0.003		SATB2	SATB homeobox 2
chr1_-_154832187	0.003	NM_170782	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chrX_-_13835012	0.003		GPM6B	glycoprotein M6B
chr6_+_30691151	0.002		TUBB	tubulin, beta class I
chr4_+_71226477	0.002	NM_012390	SMR3B SMR3A	submaxillary gland androgen regulated protein 3B submaxillary gland androgen regulated protein 3A
chr6_-_136788012	0.002	NM_001198615	MAP7	microtubule-associated protein 7
chr1_-_182922504	0.002	NM_030933	SHCBP1L	SHC SH2-domain binding protein 1-like
chr1_+_97260515	0.002
chr17_+_8213555	0.002	NM_173728	ARHGEF15	Rho guanine nucleotide exchange factor (GEF) 15
chr18_-_47806361	0.002	NM_001204151	MBD1	methyl-CpG binding domain protein 1
chr5_-_35048239	0.002	NM_031900	AGXT2	alanine--glyoxylate aminotransferase 2
chr11_+_59824054	0.001	NM_001031666 NM_001031809 NM_006138	MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr12_+_21168629	0.001	NM_001009562	SLCO1B7	solute carrier organic anion transporter family, member 1B7 (non-functional)
chr9_-_116861336	0.001	NM_138424	KIF12	kinesin family member 12
chr6_-_131321868	0.001	NM_001252660	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr8_-_62602285	0.001	NM_001164750 NM_001164751 NM_001164752 NM_001164753 NM_020164 NM_032467 NM_032468	ASPH	aspartate beta-hydroxylase
chr2_-_171923482	0.001	NM_001136555	TLK1	tousled-like kinase 1
chr10_+_102222797	0.000	NM_003393	WNT8B	wingless-type MMTV integration site family, member 8B
chr6_-_46703429	0.000	NM_001168357	PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
12.83	4.09e-03	GO:0032313	regulation of Rab GTPase activity
12.83	4.09e-03	GO:0032483	regulation of Rab protein signal transduction

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.91	1.41e-02	GO:0005576	extracellular region
1.43	3.67e-02	GO:0031224	intrinsic to membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
12.58	1.18e-03	GO:0005097	Rab GTPase activator activity