Motif ID: PBX1.p2

Z-value: 0.784


Transcription factors associated with PBX1.p2:

Gene SymbolEntrez IDGene Name
PBX1 5087 pre-B-cell leukemia homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
PBX1chr1_+_1645285860.864.9e-08Click!


Activity profile for motif PBX1.p2.

activity profile for motif PBX1.p2


Sorted Z-values histogram for motif PBX1.p2

Sorted Z-values for motif PBX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PBX1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_79258588 3.276 SYT1
synaptotagmin I
chr3_+_193853937 3.243 HES1
hairy and enhancer of split 1, (Drosophila)
chr2_+_12856813 3.160 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr3_+_193853930 2.924 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr20_-_45976626 2.650 ZMYND8
zinc finger, MYND-type containing 8
chr22_-_29137776 2.442 NM_001005735
NM_007194
NM_145862
CHEK2


checkpoint kinase 2


chr3_-_148804122 2.257 NM_003071
NM_139048
HLTF

helicase-like transcription factor

chr2_+_191745791 2.134 GLS
glutaminase
chr9_-_84304378 1.707 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr2_+_191745546 1.685 NM_014905
GLS
glutaminase
chr14_-_74551073 1.596 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr19_-_14640048 1.540 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr14_-_74551159 1.453 NM_005589
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr1_+_164528586 1.358 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr2_+_191745568 1.300 GLS
glutaminase
chr10_-_72142344 1.284 NM_018205
NM_018239
LRRC20

leucine rich repeat containing 20

chr14_-_76127158 1.207 C14orf1
chromosome 14 open reading frame 1
chr17_+_7758380 1.190 NM_203411
TMEM88
transmembrane protein 88
chr2_+_200323088 1.136


chr11_+_95523809 1.117 CEP57
centrosomal protein 57kDa

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
5.23 5.52e-04 GO:0006334 nucleosome assembly
5.18 9.08e-05 GO:0065004 protein-DNA complex assembly
4.96 1.07e-03 GO:0031497 chromatin assembly
4.91 2.00e-04 GO:0071824 protein-DNA complex subunit organization
4.71 2.00e-03 GO:0034728 nucleosome organization
4.32 5.25e-04 GO:0006333 chromatin assembly or disassembly
3.79 2.71e-02 GO:0006323 DNA packaging
2.30 2.76e-02 GO:0034621 cellular macromolecular complex subunit organization
2.22 8.81e-03 GO:0051276 chromosome organization
1.66 1.90e-02 GO:0006996 organelle organization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
7.44 3.06e-06 GO:0000786 nucleosome
5.78 3.04e-06 GO:0032993 protein-DNA complex
2.84 1.01e-02 GO:0000785 chromatin
2.43 1.11e-03 GO:0044427 chromosomal part
2.36 3.51e-04 GO:0005694 chromosome
1.53 2.12e-04 GO:0043228 non-membrane-bounded organelle
1.53 2.12e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.49 1.09e-02 GO:0070013 intracellular organelle lumen
1.46 2.26e-02 GO:0043233 organelle lumen
1.43 4.04e-02 GO:0031974 membrane-enclosed lumen
1.30 7.27e-04 GO:0044446 intracellular organelle part
1.30 8.37e-04 GO:0044422 organelle part
1.28 3.94e-03 GO:0005634 nucleus
1.25 4.86e-09 GO:0043229 intracellular organelle
1.25 6.45e-09 GO:0043226 organelle
1.22 4.63e-05 GO:0043231 intracellular membrane-bounded organelle
1.22 5.25e-05 GO:0043227 membrane-bounded organelle
1.19 7.18e-08 GO:0044424 intracellular part
1.19 5.76e-03 GO:0005737 cytoplasm
1.17 2.81e-07 GO:0005622 intracellular

Nothing significant found in function category.