Motif ID: POU1F1.p2

Z-value: 1.040


Transcription factors associated with POU1F1.p2:

Gene SymbolEntrez IDGene Name
POU1F1 5449 POU class 1 homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
POU1F1chr3_-_873256110.395.4e-02Click!


Activity profile for motif POU1F1.p2.

activity profile for motif POU1F1.p2


Sorted Z-values histogram for motif POU1F1.p2

Sorted Z-values for motif POU1F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU1F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_173020011 5.587 NM_005092
 TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr1_+_101185195 4.356 NM_001078
NM_001199834
NM_080682
 VCAM1


vascular cell adhesion molecule 1


chr4_-_76944585 3.477 NM_001565
 CXCL10
chemokine (C-X-C motif) ligand 10
chr12_+_113344811 2.704 OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr11_-_128457452 2.319 NM_001143820
 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr15_+_66694216 2.140 MAP2K1
mitogen-activated protein kinase kinase 1
chr12_+_113344738 1.965 NM_001032409
NM_002534
NM_016816
 OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr4_-_70080448 1.850 NM_001073
 UGT2B11
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B11
UDP glucuronosyltransferase 2 family, polypeptide B10
chr2_+_102770401 1.830 NM_000877
 IL1R1
interleukin 1 receptor, type I
chr12_+_78225068 1.824 NM_014903
 NAV3
neuron navigator 3
chr2_+_231281470 1.756 NM_001206704
 SP100
SP100 nuclear antigen
chr3_+_97158453 1.724 NM_173655
 EPHA6
EPH receptor A6
chr13_-_20110884 1.579 NM_001141968
NM_130785
NM_199254
 TPTE2


transmembrane phosphoinositide 3-phosphatase and tensin homolog 2


chr3_-_169487602 1.570 NM_032487
 ARPM1
actin related protein M1
chr2_+_36923832 1.544 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
 VIT




vitrin




chr5_+_54320083 1.501 NM_002104
 GZMK
granzyme K (granzyme 3; tryptase II)
chr18_+_61554938 1.481 NM_001143818
NM_002575
 SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr1_-_57045214 1.476 PPAP2B
phosphatidic acid phosphatase type 2B
chr16_+_57050985 1.443 NM_032206
 NLRC5
NLR family, CARD domain containing 5
chr11_-_8832881 1.439 NM_139157
 ST5
suppression of tumorigenicity 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
3.54 3.43e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway
3.35 1.13e-02 GO:0006805 xenobiotic metabolic process
3.35 1.13e-02 GO:0071466 cellular response to xenobiotic stimulus
3.33 1.26e-02 GO:0009410 response to xenobiotic stimulus
2.38 6.23e-03 GO:0045087 innate immune response
2.36 1.47e-07 GO:0006955 immune response
2.10 4.82e-02 GO:0050776 regulation of immune response
2.08 6.05e-05 GO:0006952 defense response
1.94 2.86e-06 GO:0002376 immune system process
1.25 2.61e-03 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
10.61 2.48e-03 GO:0042613 MHC class II protein complex
1.91 2.10e-04 GO:0005626 insoluble fraction
1.91 3.34e-04 GO:0005624 membrane fraction
1.65 6.90e-03 GO:0000267 cell fraction
1.61 2.96e-02 GO:0044421 extracellular region part
1.57 5.48e-05 GO:0005576 extracellular region
1.47 1.63e-03 GO:0044459 plasma membrane part
1.39 5.75e-06 GO:0071944 cell periphery
1.38 1.90e-05 GO:0005886 plasma membrane

Nothing significant found in function category.