Motif ID: POU2F1..3.p2

Z-value: 0.704


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
POU2F2chr19_-_426365590.232.7e-01Click!
POU2F1chr1_+_167298382-0.223.0e-01Click!
POU2F3chr11_+_120107348,
chr11_+_120110902		-0.029.1e-01Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_152214105 1.905 NM_007115
 TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr12_+_113344738 1.462 NM_001032409
NM_002534
NM_016816
 OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr6_-_11779279 1.290 NM_001143948
NM_032744
 C6orf105

chromosome 6 open reading frame 105

chr3_-_123603144 1.272 NM_053025
NM_053026
NM_053027
NM_053028
 MYLK



myosin light chain kinase



chr15_+_67458492 1.071 NM_001145104
 SMAD3
SMAD family member 3
chr1_+_68150858 1.022 NM_001199741
NM_001199742
NM_001924
 GADD45A


growth arrest and DNA-damage-inducible, alpha


chr1_+_68151092 1.011 GADD45A
growth arrest and DNA-damage-inducible, alpha
chr4_-_76944585 0.966 NM_001565
 CXCL10
chemokine (C-X-C motif) ligand 10
chr12_+_113344811 0.883 OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_-_105322056 0.883 NM_032148
 SLC41A2
solute carrier family 41, member 2
chr3_-_79817058 0.877 NM_002941
 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr21_-_36260972 0.849 NM_001001890
NM_001122607
 RUNX1

runt-related transcription factor 1

chr8_+_26435590 0.833 DPYSL2
dihydropyrimidinase-like 2
chr8_+_106331146 0.803 NM_012082
 ZFPM2
zinc finger protein, multitype 2
chr6_-_82462374 0.777 NM_017633
 FAM46A
family with sequence similarity 46, member A
chr9_+_109686436 0.772 ZNF462
zinc finger protein 462
chr1_-_205313309 0.746 KLHDC8A
kelch domain containing 8A
chr11_-_62369213 0.746 MTA2
metastasis associated 1 family, member 2
chr6_-_143266283 0.740 NM_006734
 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr14_-_106692107 0.739 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
11.14 1.52e-02 GO:0050853 B cell receptor signaling pathway
6.72 2.96e-02 GO:0030183 B cell differentiation
5.77 3.22e-02 GO:0051302 regulation of cell division
5.37 4.07e-04 GO:0006334 nucleosome assembly
5.19 2.41e-04 GO:0034728 nucleosome organization
5.09 7.95e-04 GO:0031497 chromatin assembly
4.72 8.40e-04 GO:0071824 protein-DNA complex subunit organization
4.66 2.39e-03 GO:0065004 protein-DNA complex assembly
4.18 1.89e-03 GO:0006333 chromatin assembly or disassembly
3.89 2.06e-02 GO:0006323 DNA packaging
3.73 1.71e-02 GO:0045165 cell fate commitment
3.58 2.82e-02 GO:0071103 DNA conformation change
2.28 6.17e-03 GO:0009887 organ morphogenesis
2.24 4.17e-02 GO:0008284 positive regulation of cell proliferation
2.18 2.12e-03 GO:0006955 immune response
2.09 2.33e-02 GO:0009790 embryo development
1.96 3.68e-02 GO:0006952 defense response
1.93 4.87e-04 GO:0002376 immune system process
1.77 8.09e-05 GO:0048513 organ development
1.74 3.37e-02 GO:0009893 positive regulation of metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
7.05 1.71e-05 GO:0000786 nucleosome
4.46 2.77e-03 GO:0032993 protein-DNA complex
2.91 5.44e-03 GO:0000785 chromatin

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
9.70 2.75e-06 GO:0003823 antigen binding