Motif ID: POU3F1..4.p2

Z-value: 0.556


Transcription factors associated with POU3F1..4.p2:

Gene SymbolEntrez IDGene Name
POU3F1 5453 POU class 3 homeobox 1
POU3F2 5454 POU class 3 homeobox 2
POU3F3 5455 POU class 3 homeobox 3
POU3F4 5456 POU class 3 homeobox 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
POU3F2chr6_+_992825970.395.1e-02Click!
POU3F1chr1_-_385124460.291.5e-01Click!
POU3F4chrX_+_827632680.135.4e-01Click!
POU3F3chr2_+_105471745-0.086.9e-01Click!


Activity profile for motif POU3F1..4.p2.

activity profile for motif POU3F1..4.p2


Sorted Z-values histogram for motif POU3F1..4.p2

Sorted Z-values for motif POU3F1..4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU3F1..4.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_228678556 3.911 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr2_+_152214105 2.824 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr1_-_173020011 2.717 NM_005092
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr4_-_76957139 2.472 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr18_+_61554938 2.118 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr1_-_173174611 2.111 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr19_+_4229494 1.968 NM_005755
EBI3
Epstein-Barr virus induced 3
chr13_+_97874704 1.094 MBNL2
muscleblind-like 2 (Drosophila)
chr3_+_11267666 1.040 NM_001098211
HRH1
histamine receptor H1
chr1_-_89591685 0.902 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr1_+_101185195 0.865 NM_001078
NM_001199834
NM_080682
VCAM1


vascular cell adhesion molecule 1


chr9_-_22009270 0.858 NM_004936
NM_078487
CDKN2B

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

chr12_-_57472573 0.856 NM_001130963
NM_015257
TMEM194A

transmembrane protein 194A

chr21_+_43619798 0.845 NM_207627
NM_207628
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr16_+_1728290 0.840 HN1L
hematological and neurological expressed 1-like
chr17_+_40439564 0.820 NM_003152
STAT5A
signal transducer and activator of transcription 5A
chr12_-_105322056 0.813 NM_032148
SLC41A2
solute carrier family 41, member 2
chr12_+_21168629 0.807 NM_001009562
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr9_-_32526164 0.796 NM_014314
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr7_+_28338939 0.656 NM_182899
CREB5
cAMP responsive element binding protein 5
chr5_+_113769226 0.647 NM_170775
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr17_+_25958192 0.645 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_39555993 0.614 GAST
gastrin
chr1_+_244515936 0.610 NM_001012970
C1orf100
chromosome 1 open reading frame 100
chr6_+_7402879 0.606 NM_153005
RIOK1
RIO kinase 1 (yeast)
chr13_+_97874540 0.573 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr3_-_71542628 0.568 FOXP1
forkhead box P1
chr2_-_231989755 0.519 NM_000867
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B
chr6_-_114384008 0.518 NM_153612
HS3ST5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr20_-_30539803 0.516 PDRG1
p53 and DNA-damage regulated 1
chr15_+_59908908 0.511 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr11_+_113775517 0.500 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr6_-_169654047 0.485 NM_003247
THBS2
thrombospondin 2
chr20_+_816710 0.476 NM_207121
FAM110A
family with sequence similarity 110, member A
chrX_-_52386015 0.468 NM_001079538
XAGE2B
XAGE2
X antigen family, member 2B
X antigen family, member 2
chr6_+_43738394 0.455 VEGFA
vascular endothelial growth factor A
chr11_-_64647136 0.451 EHD1
EH-domain containing 1
chr1_-_89488412 0.445 NM_018284
GBP3
guanylate binding protein 3
chrX_-_137821514 0.436 NM_033642
FGF13
fibroblast growth factor 13
chr15_-_55562483 0.436 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr7_-_92777657 0.431 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr17_+_32582295 0.430 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr1_+_50575465 0.424 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr11_+_5710926 0.422 TRIM22
tripartite motif containing 22
chr5_-_146460991 0.422 NM_181677
NM_181678
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr15_-_56209305 0.416 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr3_+_130569368 0.404 NM_001199180
NM_001199181
NM_001199182
ATP2C1


ATPase, Ca++ transporting, type 2C, member 1


chr16_+_70333058 0.398 NM_001014449
NM_001014451
NM_007242
DDX19B


DEAD (Asp-Glu-Ala-As) box polypeptide 19B


chr8_+_104310660 0.396 NM_001164615
FZD6
frizzled family receptor 6
chr8_-_20040612 0.392 NM_001135691
NM_001142324
NM_001142325
NM_003053
SLC18A1



solute carrier family 18 (vesicular monoamine), member 1



chr3_-_123339178 0.385 MYLK
myosin light chain kinase
chr1_-_42776760 0.378


chr11_-_85780899 0.377 NM_001206947
PICALM
phosphatidylinositol binding clathrin assembly protein
chr13_-_60587298 0.377 NM_030932
DIAPH3
diaphanous homolog 3 (Drosophila)
chr2_+_166428845 0.375 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr12_+_12764755 0.374 NM_001310
CREBL2
cAMP responsive element binding protein-like 2
chr12_+_93096618 0.371 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr1_+_114472438 0.367 HIPK1
homeodomain interacting protein kinase 1
chr12_+_54519836 0.363 LOC400043
uncharacterized LOC400043
chr16_+_1728256 0.356 NM_144570
HN1L
hematological and neurological expressed 1-like
chr15_+_71184781 0.345 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chr19_+_36726883 0.342 ZNF146
zinc finger protein 146
chr2_-_163099877 0.323 NM_004460
FAP
fibroblast activation protein, alpha
chr4_-_80994309 0.319 NM_001145794
NM_058172
ANTXR2

anthrax toxin receptor 2

chr10_-_69425356 0.317 NM_001127384
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr7_+_100728719 0.314 NM_030961
TRIM56
tripartite motif containing 56
chr5_+_140743755 0.312 NM_018918
NM_032054
PCDHGA5

protocadherin gamma subfamily A, 5

chr5_+_67586466 0.311 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_+_140729723 0.306 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr3_+_148447966 0.303 NM_032049
AGTR1
angiotensin II receptor, type 1
chr13_+_97928196 0.301 MBNL2
muscleblind-like 2 (Drosophila)
chr7_+_20655244 0.301 NM_001163941
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr2_+_191014971 0.300 NM_001042520
C2orf88
chromosome 2 open reading frame 88
chr21_-_35987144 0.299 NM_004414
RCAN1
regulator of calcineurin 1
chr14_-_75330535 0.297 NM_001080408
NM_001243007
PROX2

prospero homeobox 2

chr5_-_150467220 0.295 NM_001252390
TNIP1
TNFAIP3 interacting protein 1
chr13_+_43355685 0.295 NM_182508
C13orf30
chromosome 13 open reading frame 30
chr5_-_58295758 0.294 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_-_136788012 0.284 NM_001198615
MAP7
microtubule-associated protein 7
chr20_-_45061554 0.282 ELMO2
engulfment and cell motility 2
chr7_-_20256942 0.279 NM_182762
MACC1
metastasis associated in colon cancer 1
chr5_-_58652671 0.273 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_178310605 0.271 NM_004841
RASAL2
RAS protein activator like 2
chr5_+_140792507 0.268 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr8_-_15095791 0.264 NM_139167
SGCZ
sarcoglycan, zeta
chr22_+_18043147 0.264 NM_031481
SLC25A18
solute carrier family 25 (mitochondrial carrier), member 18
chr6_+_18155535 0.262 NM_153042
KDM1B
lysine (K)-specific demethylase 1B
chr7_+_28475233 0.253 NM_004904
CREB5
cAMP responsive element binding protein 5
chr9_-_19786886 0.251 NM_001193288
NM_020344
SLC24A2

solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

chr5_+_140810126 0.250 NM_003735
NM_032094
PCDHGA12

protocadherin gamma subfamily A, 12

chr10_+_111765725 0.247 NM_019903
ADD3
adducin 3 (gamma)
chr10_+_114043413 0.243 NM_058222
TECTB
tectorin beta
chr17_+_25958151 0.241 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr4_+_169418167 0.241 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr2_+_90077732 0.237


chr3_-_123339423 0.235 NM_053031
NM_053032
MYLK

myosin light chain kinase

chrM_+_5513 0.235


chr1_+_32666201 0.234 NM_024296
CCDC28B
coiled-coil domain containing 28B
chr19_+_58180302 0.230 NM_152677
ZSCAN4
zinc finger and SCAN domain containing 4
chr17_-_60884010 0.229 NM_001100875
MARCH10
membrane-associated ring finger (C3HC4) 10
chr17_-_64225496 0.228 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr1_+_79086087 0.227 NM_006820
IFI44L
interferon-induced protein 44-like
chr10_+_91087601 0.223 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr3_-_99594915 0.223 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr2_-_180610768 0.222 NM_001113397
ZNF385B
zinc finger protein 385B
chr18_+_59157774 0.222 NM_031891
CDH20
cadherin 20, type 2
chr10_-_81708860 0.221 NM_003019
SFTPD
surfactant protein D
chr5_+_140810181 0.218 PCDHGA12
protocadherin gamma subfamily A, 12
chr12_+_102271082 0.216 NM_018370
DRAM1
DNA-damage regulated autophagy modulator 1
chr21_-_15755439 0.215 NM_006948
HSPA13
heat shock protein 70kDa family, member 13
chr2_+_108994366 0.214 NM_006588
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr4_+_88896868 0.212 SPP1
secreted phosphoprotein 1
chrX_+_52113157 0.211 NM_001079538
XAGE2B
XAGE2
X antigen family, member 2B
X antigen family, member 2
chr5_-_140895407 0.210 DIAPH1
diaphanous homolog 1 (Drosophila)
chr2_+_68872953 0.210 NM_138964
PROKR1
prokineticin receptor 1
chrX_+_48114796 0.208 NM_005635
SSX1
synovial sarcoma, X breakpoint 1
chr10_+_124151818 0.206 NM_021622
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr21_+_27011588 0.204 NM_021219
JAM2
junctional adhesion molecule 2
chr20_-_30539853 0.203 NM_030815
PDRG1
p53 and DNA-damage regulated 1
chr2_-_201936386 0.203 FAM126B
family with sequence similarity 126, member B
chr4_+_88896838 0.200 SPP1
secreted phosphoprotein 1
chr18_+_55888838 0.199 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr5_+_34684611 0.198 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr7_-_84751246 0.198 NM_152754
SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr6_-_46293404 0.198 RCAN2
regulator of calcineurin 2
chr6_+_31543340 0.197 NM_000594
TNF
tumor necrosis factor
chr21_-_43346780 0.196 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr3_-_124653571 0.194 NM_033049
MUC13
mucin 13, cell surface associated
chr11_-_8954534 0.193 NM_020643
C11orf16
chromosome 11 open reading frame 16
chr16_+_1728283 0.192 HN1L
hematological and neurological expressed 1-like
chr7_-_126883568 0.191 NM_000845
GRM8
glutamate receptor, metabotropic 8
chr18_-_3845295 0.191 NM_001003809
NM_001242765
NM_001242766
DLGAP1


discs, large (Drosophila) homolog-associated protein 1


chr5_+_141348450 0.190 NM_004290
NM_183398
NM_183400
RNF14


ring finger protein 14


chr17_-_2996289 0.189 NM_002548
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr5_+_65372744 0.189 ERBB2IP
erbb2 interacting protein
chr17_+_42925278 0.187 NM_016438
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr4_+_68424444 0.183 NM_012108
STAP1
signal transducing adaptor family member 1
chrX_-_48327739 0.179 SLC38A5
solute carrier family 38, member 5
chr14_+_32798478 0.178 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr11_-_55703875 0.178 NM_006637
OR5I1
olfactory receptor, family 5, subfamily I, member 1
chr17_+_57642885 0.178 NM_001166301
NM_024612
DHX40

DEAH (Asp-Glu-Ala-His) box polypeptide 40

chr11_-_85469043 0.177 NM_001162951
NM_001162953
SYTL2

synaptotagmin-like 2

chr17_-_41739261 0.176 NM_001040002
MEOX1
mesenchyme homeobox 1
chr15_+_42066690 0.174 MAPKBP1
mitogen-activated protein kinase binding protein 1
chr2_+_68961912 0.174 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr3_-_119278402 0.173 NM_005191
CD80
CD80 molecule
chr4_+_74269971 0.173 NM_000477
ALB
albumin
chr12_-_91398757 0.173 NM_004950
EPYC
epiphycan
chr2_+_166095911 0.170 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr12_-_58135853 0.168 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr18_+_23806385 0.168 NM_005640
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr12_-_16759733 0.167 NM_001243610
LMO3
LIM domain only 3 (rhombotin-like 2)
chr9_+_99691285 0.166 NM_001045477
NM_001170741
FAM22G

family with sequence similarity 22, member G

chr18_+_55888750 0.166 NM_001144966
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr6_+_27925018 0.166 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr21_-_40816127 0.165 NM_152505
LCA5L
Leber congenital amaurosis 5-like
chr2_-_77749335 0.165 NM_001134745
NM_024993
LRRTM4

leucine rich repeat transmembrane neuronal 4

chrX_+_96138906 0.164 NM_013347
RPA4
replication protein A4, 30kDa
chr5_+_159848835 0.163 NM_004219
PTTG1
pituitary tumor-transforming 1
chrX_+_106871739 0.163 PRPS1
phosphoribosyl pyrophosphate synthetase 1
chr2_-_113594325 0.161 NM_000576
IL1B
interleukin 1, beta
chr6_-_152702450 0.161 SYNE1
spectrin repeat containing, nuclear envelope 1
chr5_+_140809957 0.160 PCDHGA12
protocadherin gamma subfamily A, 12
chr14_+_51026742 0.160 NM_015915
NM_181598
ATL1

atlastin GTPase 1

chr3_-_167191808 0.159 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr10_+_29698482 0.157 LOC387647
patched domain containing 3 pseudogene
chr5_-_98262217 0.157 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr7_+_45933096 0.155


chr8_+_104831415 0.154 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr12_-_16759939 0.154 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chrX_+_144908927 0.152 NM_004709
CXorf1
chromosome X open reading frame 1
chr9_+_96233420 0.152 FAM120A
family with sequence similarity 120A
chr2_-_31352489 0.152 NM_001253827
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr8_-_6420454 0.152 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr1_+_12916940 0.151 NM_023014
PRAMEF2
PRAME family member 2
chr14_-_35344852 0.150 NM_013448
NM_182648
BAZ1A

bromodomain adjacent to zinc finger domain, 1A

chr6_-_131291480 0.150 NM_001199389
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr1_-_157811491 0.149 NM_005894
CD5L
CD5 molecule-like
chr3_+_121613170 0.149 NM_001145998
NM_021082
SLC15A2

solute carrier family 15 (H+/peptide transporter), member 2

chr6_+_144185572 0.149 NM_001013623
C6orf94
chromosome 6 open reading frame 94
chr5_-_13944588 0.149 NM_001369
DNAH5
dynein, axonemal, heavy chain 5
chr19_-_7040183 0.147 NM_001164419
MBD3L4
methyl-CpG binding domain protein 3-like 4
chrX_+_9431314 0.147 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr19_-_14939275 0.147 NM_017506
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr11_-_72504643 0.147 NM_006645
STARD10
StAR-related lipid transfer (START) domain containing 10
chr12_-_91505215 0.146 LUM
lumican
chr7_+_29519485 0.144 NM_001039936
CHN2
chimerin (chimaerin) 2
chr12_+_41831484 0.143 NM_013377
PDZRN4
PDZ domain containing ring finger 4
chr9_+_92219926 0.143 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr5_+_70944968 0.142 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr3_-_46718898 0.141 NM_182775
ALS2CL
ALS2 C-terminal like
chr16_+_6823809 0.141 NM_001142334
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr17_+_56315786 0.140 NM_001160102
NM_006151
LPO

lactoperoxidase

chr2_-_113542970 0.140 NM_000575
IL1A
interleukin 1, alpha
chr17_+_4675175 0.140 NM_003963
TM4SF5
transmembrane 4 L six family member 5
chr2_-_37544165 0.139 NM_005813
PRKD3
protein kinase D3
chr3_+_75713480 0.139 NM_001124759
FRG2C
FLJ20518
FSHD region gene 2 family, member C
FSHD region gene 2 family, member C pseudogene
chr10_+_90750287 0.139 NM_000043
NM_152871
NM_152872
FAS


Fas (TNF receptor superfamily, member 6)


chr3_+_99833773 0.138 NM_001167924
C3orf26
chromosome 3 open reading frame 26
chr3_-_150920946 0.137 NM_013308
GPR171
G protein-coupled receptor 171

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.47 6.49e-06 GO:0051716 cellular response to stimulus
1.35 6.76e-06 GO:0050896 response to stimulus
1.52 2.32e-05 GO:0007165 signal transduction
1.46 1.50e-04 GO:0023052 signaling
2.53 9.63e-04 GO:0002684 positive regulation of immune system process
2.08 2.68e-03 GO:0006955 immune response
1.92 5.45e-03 GO:0070887 cellular response to chemical stimulus
1.77 6.42e-03 GO:0002376 immune system process
3.52 2.37e-02 GO:0050870 positive regulation of T cell activation
2.56 4.77e-02 GO:0019932 second-messenger-mediated signaling
1.96 4.89e-02 GO:0002682 regulation of immune system process
3.32 4.92e-02 GO:0032147 activation of protein kinase activity

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.94 2.00e-03 GO:0005615 extracellular space
1.80 2.43e-03 GO:0044421 extracellular region part
1.33 3.59e-03 GO:0005886 plasma membrane
1.33 3.74e-03 GO:0071944 cell periphery
12.28 7.53e-03 GO:0005942 phosphatidylinositol 3-kinase complex
1.50 7.53e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.72 9.52e-03 GO:0008201 heparin binding
12.28 1.16e-02 GO:0035004 phosphatidylinositol 3-kinase activity
3.15 1.20e-02 GO:0001871 pattern binding
3.15 1.20e-02 GO:0030247 polysaccharide binding
3.21 1.64e-02 GO:0005539 glycosaminoglycan binding