Motif ID: POU3F1..4.p2

Z-value: 0.556


Transcription factors associated with POU3F1..4.p2:

Gene SymbolEntrez IDGene Name
POU3F1 5453 POU class 3 homeobox 1
POU3F2 5454 POU class 3 homeobox 2
POU3F3 5455 POU class 3 homeobox 3
POU3F4 5456 POU class 3 homeobox 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
POU3F2chr6_+_992825970.395.1e-02Click!
POU3F1chr1_-_385124460.291.5e-01Click!
POU3F4chrX_+_827632680.135.4e-01Click!
POU3F3chr2_+_105471745-0.086.9e-01Click!


Activity profile for motif POU3F1..4.p2.

activity profile for motif POU3F1..4.p2


Sorted Z-values histogram for motif POU3F1..4.p2

Sorted Z-values for motif POU3F1..4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU3F1..4.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_228678556 3.911 NM_001130046
NM_004591
 CCL20

chemokine (C-C motif) ligand 20

chr2_+_152214105 2.824 NM_007115
 TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr1_-_173020011 2.717 NM_005092
 TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr4_-_76957139 2.472 NM_005409
 CXCL11
chemokine (C-X-C motif) ligand 11
chr18_+_61554938 2.118 NM_001143818
NM_002575
 SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr1_-_173174611 2.111 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr19_+_4229494 1.968 NM_005755
 EBI3
Epstein-Barr virus induced 3
chr13_+_97874704 1.094 MBNL2
muscleblind-like 2 (Drosophila)
chr3_+_11267666 1.040 NM_001098211
 HRH1
histamine receptor H1
chr1_-_89591685 0.902 NM_004120
 GBP2
guanylate binding protein 2, interferon-inducible
chr1_+_101185195 0.865 NM_001078
NM_001199834
NM_080682
 VCAM1


vascular cell adhesion molecule 1


chr9_-_22009270 0.858 NM_004936
NM_078487
 CDKN2B

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

chr12_-_57472573 0.856 NM_001130963
NM_015257
 TMEM194A

transmembrane protein 194A

chr21_+_43619798 0.845 NM_207627
NM_207628
 ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr16_+_1728290 0.840 HN1L
hematological and neurological expressed 1-like
chr17_+_40439564 0.820 NM_003152
 STAT5A
signal transducer and activator of transcription 5A
chr12_-_105322056 0.813 NM_032148
 SLC41A2
solute carrier family 41, member 2
chr12_+_21168629 0.807 NM_001009562
 SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr9_-_32526164 0.796 NM_014314
 DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr7_+_28338939 0.656 NM_182899
 CREB5
cAMP responsive element binding protein 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
3.52 2.37e-02 GO:0050870 positive regulation of T cell activation
3.32 4.92e-02 GO:0032147 activation of protein kinase activity
2.56 4.77e-02 GO:0019932 second-messenger-mediated signaling
2.53 9.63e-04 GO:0002684 positive regulation of immune system process
2.08 2.68e-03 GO:0006955 immune response
1.96 4.89e-02 GO:0002682 regulation of immune system process
1.92 5.45e-03 GO:0070887 cellular response to chemical stimulus
1.77 6.42e-03 GO:0002376 immune system process
1.52 2.32e-05 GO:0007165 signal transduction
1.47 6.49e-06 GO:0051716 cellular response to stimulus
1.46 1.50e-04 GO:0023052 signaling
1.35 6.76e-06 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
12.28 7.53e-03 GO:0005942 phosphatidylinositol 3-kinase complex
1.94 2.00e-03 GO:0005615 extracellular space
1.80 2.43e-03 GO:0044421 extracellular region part
1.50 7.53e-03 GO:0005576 extracellular region
1.33 3.59e-03 GO:0005886 plasma membrane
1.33 3.74e-03 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
12.28 1.16e-02 GO:0035004 phosphatidylinositol 3-kinase activity
3.72 9.52e-03 GO:0008201 heparin binding
3.21 1.64e-02 GO:0005539 glycosaminoglycan binding
3.15 1.20e-02 GO:0001871 pattern binding
3.15 1.20e-02 GO:0030247 polysaccharide binding