Motif ID: POU5F1.p2

Z-value: 1.390


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
POU5F1chr6_-_311346140.491.3e-02Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_41700736 16.213 LIMCH1
LIM and calponin homology domains 1
chr9_-_14086901 9.456 NFIB
nuclear factor I/B
chr1_+_61542928 9.387 NM_001145511
NFIA
nuclear factor I/A
chr4_-_186733372 6.326 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr3_-_64211111 6.007 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr1_+_61547388 5.959 NM_001145512
NFIA
nuclear factor I/A
chr4_+_41614933 5.104 LIMCH1
LIM and calponin homology domains 1
chr4_+_41614911 5.016 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr1_+_164528586 4.962 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr4_+_41614725 4.934 LIMCH1
LIM and calponin homology domains 1
chr18_-_53089722 4.898 NM_001243233
TCF4
transcription factor 4
chr1_+_84609941 4.825 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr8_-_93111915 4.693 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_+_67410825 4.459 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr5_-_88119604 4.140 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr1_+_61547625 3.667 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr13_-_77460432 3.646 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr10_-_116286661 3.521 NM_006720
ABLIM1
actin binding LIM protein 1
chr3_-_18480203 3.328 NM_001131010
SATB1
SATB homeobox 1
chr1_+_228645807 3.142 NM_175055
HIST3H2BB
histone cluster 3, H2bb

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 42 entries
enrichment   p-value GO term description
9.24 1.98e-02 GO:0060216 definitive hemopoiesis
4.30 2.06e-03 GO:0050909 sensory perception of taste
3.40 2.92e-02 GO:0048704 embryonic skeletal system morphogenesis
3.12 1.02e-02 GO:0048706 embryonic skeletal system development
1.98 9.50e-05 GO:0006325 chromatin organization
1.87 3.13e-02 GO:0016568 chromatin modification
1.72 4.65e-03 GO:0051276 chromosome organization
1.62 2.96e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.60 2.83e-04 GO:0010646 regulation of cell communication
1.56 1.59e-02 GO:0006351 transcription, DNA-dependent
1.54 9.66e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.53 6.12e-05 GO:0007399 nervous system development
1.45 5.91e-06 GO:0006355 regulation of transcription, DNA-dependent
1.44 3.91e-02 GO:0009893 positive regulation of metabolic process
1.43 2.77e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.43 1.08e-05 GO:0051252 regulation of RNA metabolic process
1.41 6.45e-06 GO:0010468 regulation of gene expression
1.41 8.82e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.41 9.52e-04 GO:0048513 organ development
1.40 3.10e-04 GO:0048523 negative regulation of cellular process

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
3.29 6.56e-03 GO:0000786 nucleosome
2.09 3.60e-03 GO:0000785 chromatin
1.22 1.24e-05 GO:0005634 nucleus
1.08 4.28e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
6.57 4.72e-03 GO:0008527 taste receptor activity
3.42 1.15e-02 GO:0004879 ligand-dependent nuclear receptor activity
3.38 2.52e-02 GO:0003707 steroid hormone receptor activity
1.84 2.44e-06 GO:0043565 sequence-specific DNA binding
1.67 3.89e-06 GO:0001071 nucleic acid binding transcription factor activity
1.67 3.89e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.63 1.68e-05 GO:0030528 transcription regulator activity
1.41 3.79e-06 GO:0003677 DNA binding
1.25 4.75e-03 GO:0003676 nucleic acid binding
1.15 7.54e-04 GO:0005515 protein binding
1.09 1.96e-04 GO:0005488 binding