Motif ID: POU6F1.p2

Z-value: 0.445


Transcription factors associated with POU6F1.p2:

Gene SymbolEntrez IDGene Name
POU6F1 5463 POU class 6 homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
POU6F1chr12_-_515919490.301.5e-01Click!


Activity profile for motif POU6F1.p2.

activity profile for motif POU6F1.p2


Sorted Z-values histogram for motif POU6F1.p2

Sorted Z-values for motif POU6F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU6F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_90033967 0.914 NM_145715
TIGD2
tigger transposable element derived 2
chrX_+_65382432 0.901 NM_138737
HEPH
hephaestin
chr3_-_18480203 0.830 NM_001131010
SATB1
SATB homeobox 1
chr7_-_27183225 0.809 NM_019102
HOXA5
homeobox A5
chr1_-_76397975 0.781 NM_080868
ASB17
ankyrin repeat and SOCS box containing 17
chr1_+_84768333 0.762 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr17_-_48945338 0.761 NM_001243877
TOB1
transducer of ERBB2, 1
chr7_-_27159213 0.471 NM_030661
HOXA3
homeobox A3
chr7_+_100026412 0.458 NM_001194990
NM_001194991
NM_001194992
MEPCE


methylphosphate capping enzyme


chr4_+_41614911 0.434 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr8_-_93075190 0.425 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_+_97889467 0.418 NM_014803
ZNF518A
zinc finger protein 518A
chr7_+_100027253 0.418 NM_019606
MEPCE
methylphosphate capping enzyme
chr18_+_47088400 0.415 NM_006033
LIPG
lipase, endothelial
chr19_+_39899749 0.414


chr3_-_74570262 0.397 NM_020872
CNTN3
contactin 3 (plasmacytoma associated)
chr6_-_26108320 0.394 NM_005323
HIST1H1T
histone cluster 1, H1t
chr22_+_22735202 0.370


chr8_-_93111915 0.364 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_-_14132920 0.338 NM_000834
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr3_+_127641901 0.335 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr11_-_27681195 0.332 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor

chr7_+_100026413 0.319 MEPCE
methylphosphate capping enzyme
chr4_+_41614725 0.313 LIMCH1
LIM and calponin homology domains 1
chr8_-_93107881 0.302 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chrX_+_65382627 0.292 HEPH
hephaestin
chr5_+_139505519 0.289 NM_001007189
IGIP
IgA-inducing protein homolog (Bos taurus)
chr17_-_67240955 0.286 NM_080282
ABCA10
ATP-binding cassette, sub-family A (ABC1), member 10
chr13_-_52980628 0.283 NM_018676
NM_199263
THSD1

thrombospondin, type I, domain containing 1

chr6_+_88182679 0.274 SLC35A1
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr19_-_22379752 0.272 NM_001001411
ZNF676
zinc finger protein 676
chr11_+_5509914 0.264 NM_001005163
OR52D1
olfactory receptor, family 52, subfamily D, member 1
chr13_-_45010974 0.260 TSC22D1
TSC22 domain family, member 1
chr4_+_41614933 0.256 LIMCH1
LIM and calponin homology domains 1
chr6_+_88182624 0.254 NM_001168398
NM_006416
SLC35A1

solute carrier family 35 (CMP-sialic acid transporter), member A1

chr1_-_116311161 0.250 CASQ2
calsequestrin 2 (cardiac muscle)
chr13_-_45010937 0.250 TSC22D1
TSC22 domain family, member 1
chr5_+_140602914 0.248 NM_018934
PCDHB14
protocadherin beta 14
chr13_-_45010994 0.244 TSC22D1
TSC22 domain family, member 1
chr1_-_116311330 0.240 CASQ2
calsequestrin 2 (cardiac muscle)
chr6_-_130031278 0.235 NM_033515
ARHGAP18
Rho GTPase activating protein 18
chr1_-_116311398 0.235 NM_001232
CASQ2
calsequestrin 2 (cardiac muscle)
chr18_+_8717368 0.233 NM_015210
CCDC165
coiled-coil domain containing 165
chr22_-_22863504 0.232 NM_080764
ZNF280B
zinc finger protein 280B
chr1_+_84647342 0.228 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr10_+_94594469 0.220 NM_001013848
EXOC6
exocyst complex component 6
chr1_+_61869699 0.217 NFIA
nuclear factor I/A
chr2_-_158731622 0.211 NM_001105
ACVR1
activin A receptor, type I
chr12_-_11150473 0.210 NM_176889
TAS2R20
taste receptor, type 2, member 20
chr6_+_144612872 0.208 NM_007124
UTRN
utrophin
chr19_-_48759141 0.204 NM_001184902
NM_001184904
CARD8

caspase recruitment domain family, member 8

chr3_+_46919235 0.204 NM_000316
PTH1R
parathyroid hormone 1 receptor
chr12_-_11214892 0.202 NM_176887
TAS2R46
taste receptor, type 2, member 46
chr4_+_36285643 0.201 NM_001170700
DTHD1
death domain containing 1
chr3_+_97868169 0.201 NM_001005514
OR5H14
olfactory receptor, family 5, subfamily H, member 14
chr9_+_19290748 0.200 NM_017925
DENND4C
DENN/MADD domain containing 4C
chr12_-_51611476 0.198 POU6F1
POU class 6 homeobox 1
chrX_-_106146546 0.194 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chrX_-_135962872 0.191 RBMX
RNA binding motif protein, X-linked
chr10_+_69869249 0.188 NM_032578
MYPN
myopalladin
chr1_+_15272414 0.183 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr10_+_5005685 0.180 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr11_+_22696318 0.178 NM_005256
GAS2
growth arrest-specific 2
chr1_+_78470593 0.174 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr5_-_137475076 0.171 NM_003551
NME5
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr11_+_107879407 0.168 NM_003478
CUL5
cullin 5
chr5_+_147795459 0.162 FBXO38
F-box protein 38
chr1_+_153003677 0.158 NM_003125
SPRR1B
small proline-rich protein 1B
chr2_+_190540710 0.157 NM_144708
ANKAR
ankyrin and armadillo repeat containing
chr12_-_9885859 0.152 NM_001253748
NM_001253750
NM_172004
CLECL1


C-type lectin-like 1


chrX_-_33229428 0.143 NM_004006
DMD
dystrophin
chr10_-_5045967 0.143 NM_001135241
AKR1C2
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr11_-_124253238 0.140 NM_001005468
OR8B2
olfactory receptor, family 8, subfamily B, member 2
chr16_-_32688052 0.140 NM_016212
TP53TG3
TP53 target 3
chr2_-_72371188 0.139 CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr16_+_33261514 0.138 NM_016212
TP53TG3
TP53 target 3
chr2_+_38155901 0.137 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chr7_+_94297448 0.136 PEG10
paternally expressed 10
chr11_-_26593667 0.134 NM_001135091
NM_001135092
NM_145650
MUC15


mucin 15, cell surface associated


chr12_-_11062160 0.133 NM_023920
TAS2R13
taste receptor, type 2, member 13
chr22_+_39101954 0.132 GTPBP1
GTP binding protein 1
chr12_+_25205488 0.130 LRMP
lymphoid-restricted membrane protein
chr10_+_5005453 0.129 NM_001353
AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr15_+_40294749 0.125 EIF2AK4
eukaryotic translation initiation factor 2 alpha kinase 4
chr9_+_35041101 0.121 NM_001040411
NM_001040412
C9orf131

chromosome 9 open reading frame 131

chr17_+_3379295 0.120 NM_000049
ASPA
aspartoacylase
chr3_-_13057130 0.120


chr19_-_48752921 0.118 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr7_-_64023454 0.117 NM_001130022
NM_178558
ZNF680

zinc finger protein 680

chr16_+_33204979 0.116 NM_016212
TP53TG3
TP53 target 3
chr15_+_74422920 0.114 ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr8_+_87111132 0.113 NM_152565
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr1_+_84874033 0.113 NM_058248
DNASE2B
deoxyribonuclease II beta
chr13_+_24144402 0.112 NM_001204459
NM_148957
TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr5_-_75919051 0.110 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr5_+_68710938 0.109 NM_001038603
NM_001244734
MARVELD2

MARVEL domain containing 2

chrX_-_55057408 0.109 NM_000032
NM_001037967
NM_001037968
ALAS2


aminolevulinate, delta-, synthase 2


chr4_+_71587674 0.105 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr11_+_22689653 0.104 NM_177553
GAS2
growth arrest-specific 2
chr3_-_56698073 0.104 NM_015224
FAM208A
family with sequence similarity 208, member A
chr3_+_142375738 0.102 NM_001172312
PLS1
plastin 1
chr17_+_67498391 0.102 MAP2K6
mitogen-activated protein kinase kinase 6
chr20_+_32150139 0.101 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr6_+_132891460 0.101 NM_175067
TAAR6
trace amine associated receptor 6
chr19_-_21950322 0.100 NM_173531
ZNF100
zinc finger protein 100
chr3_-_57678594 0.097 NM_152678
FAM116A
family with sequence similarity 116, member A
chr2_+_176969233 0.097


chr15_+_74422742 0.097 NM_020851
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr1_-_197036350 0.097 NM_001994
F13B
coagulation factor XIII, B polypeptide
chr3_+_186330859 0.096 AHSG
alpha-2-HS-glycoprotein
chr17_-_66951381 0.094 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr6_-_150057659 0.093 NUP43
nucleoporin 43kDa
chr8_-_38205652 0.093 WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr6_+_42788793 0.090 NM_015349
KIAA0240
KIAA0240
chr1_+_198608216 0.089 PTPRC
protein tyrosine phosphatase, receptor type, C
chr13_+_108921976 0.088 NM_001145645
NM_006573
TNFSF13B

tumor necrosis factor (ligand) superfamily, member 13b

chr4_-_144826659 0.088 NM_002102
NM_198682
GYPE

glycophorin E (MNS blood group)

chr4_-_140060601 0.088 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr15_-_31393906 0.086 NM_001252024
NM_001252030
NM_002420
TRPM1


transient receptor potential cation channel, subfamily M, member 1


chr3_-_185826748 0.086 NM_004454
ETV5
ets variant 5
chr16_+_82068958 0.086 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chrX_+_47053213 0.085 UBA1
ubiquitin-like modifier activating enzyme 1
chr17_+_3377346 0.084 NM_001128085
ASPA
aspartoacylase
chrX_+_47053192 0.083 NM_003334
UBA1
ubiquitin-like modifier activating enzyme 1
chr16_-_31439650 0.083 NM_005205
COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
chr17_-_54893249 0.082 NM_001085430
C17orf67
chromosome 17 open reading frame 67
chr18_+_616671 0.082 NM_199167
CLUL1
clusterin-like 1 (retinal)
chrX_-_100548044 0.081 NM_024885
TAF7L
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr8_-_12973752 0.081 NM_001164271
DLC1
deleted in liver cancer 1
chr12_+_20963637 0.081 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr7_+_39017608 0.080 NM_001166018
NM_007252
POU6F2

POU class 6 homeobox 2

chr12_-_7848324 0.080 NM_020634
GDF3
growth differentiation factor 3
chr10_+_29577989 0.079 NM_032517
LYZL1
lysozyme-like 1
chr16_+_82068910 0.077 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chrX_-_32173585 0.077 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr1_-_160617042 0.077 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr2_-_106055229 0.077 NM_201557
FHL2
four and a half LIM domains 2
chr7_-_38948776 0.077 NM_014396
NM_080631
VPS41

vacuolar protein sorting 41 homolog (S. cerevisiae)

chrX_+_150884506 0.076 NM_033085
FATE1
fetal and adult testis expressed 1
chr7_-_99766191 0.075 GAL3ST4
galactose-3-O-sulfotransferase 4
chr7_-_100425035 0.075 NM_004444
EPHB4
EPH receptor B4
chr6_-_49834188 0.073 NM_001131
NM_170609
CRISP1

cysteine-rich secretory protein 1

chr21_-_31744546 0.073 NM_181621
KRTAP13-2
keratin associated protein 13-2
chr6_+_154407641 0.071 NM_001145287
OPRM1
opioid receptor, mu 1
chr17_-_10372875 0.070 NM_017533
MYH4
myosin, heavy chain 4, skeletal muscle
chr4_-_72649734 0.070 NM_000583
GC
group-specific component (vitamin D binding protein)
chrX_-_33357725 0.070 NM_000109
DMD
dystrophin
chrX_+_47053227 0.068 UBA1
ubiquitin-like modifier activating enzyme 1
chr11_+_87032428 0.067 TMEM135
transmembrane protein 135
chr7_-_64023444 0.067


chrX_+_47053271 0.067 UBA1
ubiquitin-like modifier activating enzyme 1
chr3_+_142442855 0.066


chr10_+_5005601 0.066 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr3_-_105421044 0.065 CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr6_-_29323971 0.065 NM_030876
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr7_-_99766238 0.065 NM_024637
GAL3ST4
galactose-3-O-sulfotransferase 4
chr5_+_161274196 0.065 NM_000806
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr3_+_186330711 0.065 AHSG
alpha-2-HS-glycoprotein
chr5_+_140220811 0.064 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr7_+_94292737 0.064 PEG10
paternally expressed 10
chr7_-_41742666 0.063 NM_002192
INHBA
inhibin, beta A
chr10_-_11574273 0.063 NM_001080491
USP6NL
USP6 N-terminal like
chr1_+_186798031 0.063 NM_024420
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr2_+_201756639 0.062 NM_001142356
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr17_-_29641068 0.062 EVI2B
ecotropic viral integration site 2B
chr10_-_128209996 0.061 NM_001004298
C10orf90
chromosome 10 open reading frame 90
chr6_-_138189313 0.061


chr4_-_2230957 0.061 NM_181808
POLN
polymerase (DNA directed) nu
chr2_+_28718937 0.060 NM_001170585
NM_153021
PLB1

phospholipase B1

chr3_+_180320955 0.060 TTC14
tetratricopeptide repeat domain 14
chr2_-_183387063 0.060 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr16_-_71323090 0.059 NM_001099642
NM_018348
FTSJD1

FtsJ methyltransferase domain containing 1

chr19_-_38188344 0.058 ZNF607
zinc finger protein 607
chr17_-_2996289 0.056 NM_002548
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chrX_+_86772714 0.056 NM_019117
NM_057162
KLHL4

kelch-like 4 (Drosophila)

chr4_+_40198526 0.055 NM_004310
RHOH
ras homolog gene family, member H
chr1_-_160549271 0.054 NM_001184879
NM_001184881
NM_001184882
NM_003874
CD84



CD84 molecule



chr2_-_142889269 0.054 NM_018557
LRP1B
low density lipoprotein receptor-related protein 1B
chr2_+_29038862 0.054 NM_001008779
SPDYA
speedy homolog A (Xenopus laevis)
chr10_+_74870209 0.053 NM_015901
NUDT13
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr2_-_241080072 0.053 NM_148961
OTOS
otospiralin
chr1_+_167189948 0.053 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr17_+_17608163 0.053


chr12_-_90049818 0.052 NM_001001323
NM_001682
ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr12_-_11175169 0.052 NM_176888
TAS2R19
taste receptor, type 2, member 19
chr9_-_99145876 0.051 SLC35D2
solute carrier family 35, member D2
chr12_-_59314069 0.050 NM_153377
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr2_+_202098165 0.050 NM_001080124
NM_001228
NM_033355
NM_033358
CASP8



caspase 8, apoptosis-related cysteine peptidase



chr7_+_120702818 0.049 C7orf58
chromosome 7 open reading frame 58
chr5_+_92918924 0.049 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr14_+_32047121 0.048 NM_001201573
NUBPL
nucleotide binding protein-like
chr1_+_67773046 0.048 NM_001559
IL12RB2
interleukin 12 receptor, beta 2
chr7_+_107110501 0.047 NM_005295
GPR22
G protein-coupled receptor 22
chr1_+_109255555 0.047 NM_001144937
FNDC7
fibronectin type III domain containing 7
chr10_+_32856650 0.047 NM_024688
C10orf68
chromosome 10 open reading frame 68
chr10_-_30918625 0.046 NM_183058
LYZL2
lysozyme-like 2
chr3_-_111314181 0.046 NM_024508
ZBED2
zinc finger, BED-type containing 2
chr20_-_20036685 0.046 NM_016652
CRNKL1
crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr5_+_161274684 0.046 NM_001127643
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr1_+_18081807 0.046 NM_030812
ACTL8
actin-like 8

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.37 1.41e-02 GO:0071944 cell periphery
1.54 2.13e-02 GO:0044459 plasma membrane part
1.35 2.90e-02 GO:0005886 plasma membrane
1.74 3.64e-02 GO:0005887 integral to plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.88 6.29e-05 GO:0004872 receptor activity
1.70 7.62e-04 GO:0004871 signal transducer activity
1.70 7.62e-04 GO:0060089 molecular transducer activity
1.92 1.26e-03 GO:0004888 transmembrane receptor activity
32.73 1.43e-02 GO:0047023 androsterone dehydrogenase activity
32.73 1.43e-02 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
2.01 1.58e-02 GO:0004930 G-protein coupled receptor activity