Motif ID: PRDM1.p3

Z-value: 2.973


Transcription factors associated with PRDM1.p3:

Gene SymbolEntrez IDGene Name
PRDM1 639 PR domain containing 1, with ZNF domain

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
PRDM1chr6_+_1065341880.452.4e-02Click!


Activity profile for motif PRDM1.p3.

activity profile for motif PRDM1.p3


Sorted Z-values histogram for motif PRDM1.p3

Sorted Z-values for motif PRDM1.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM1.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_29527477 44.240 UBD
ubiquitin D
chr6_-_29527701 43.185 NM_006398
 UBD
ubiquitin D
chr6_+_32821924 23.739 NM_002800
 PSMB9
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
chr22_-_36556781 22.126 NM_145640
 APOL3
apolipoprotein L, 3
chr4_+_142557722 19.345 NM_000585
NM_172175
 IL15

interleukin 15

chr16_-_67970734 18.968 NM_002801
 PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr6_-_32806545 17.783 NM_000544
NM_018833
 TAP2

transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)

chr17_+_6659155 16.959 NM_017523
NM_199139
 XAF1

XIAP associated factor 1

chr16_-_67970651 15.623 PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr11_-_4414887 15.540 NM_003141
 TRIM21
tripartite motif containing 21
chr1_+_212781969 15.534 NM_001040619
NM_001206484
NM_001206488
NM_001674
 ATF3



activating transcription factor 3



chr1_+_212782103 14.278 ATF3
activating transcription factor 3
chr17_+_6659356 13.420 XAF1
XIAP associated factor 1
chr5_+_131746579 13.028 C5orf56
chromosome 5 open reading frame 56
chr6_+_127439803 12.975 RSPO3
R-spondin 3
chr6_+_127440047 12.254 NM_032784
 RSPO3
R-spondin 3
chr4_+_186990308 11.299 NM_003265
 TLR3
toll-like receptor 3
chr11_+_71710971 10.814 NM_001145055
 IL18BP
interleukin 18 binding protein
chr21_+_43933983 10.454 SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr1_+_110453232 9.950 NM_000757
NM_172210
NM_172212
 CSF1


colony stimulating factor 1 (macrophage)



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
61.98 1.33e-04 GO:0002483 antigen processing and presentation of endogenous peptide antigen
61.98 1.33e-04 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I
44.27 9.13e-04 GO:0019883 antigen processing and presentation of endogenous antigen
38.74 4.11e-02 GO:0016553 base conversion or substitution editing
23.84 1.75e-02 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
10.00 1.24e-03 GO:0060337 type I interferon-mediated signaling pathway
10.00 1.24e-03 GO:0071357 cellular response to type I interferon
9.84 1.41e-03 GO:0034340 response to type I interferon
7.21 1.50e-02 GO:0030330 DNA damage response, signal transduction by p53 class mediator
3.39 4.01e-02 GO:0045087 innate immune response
2.96 7.37e-04 GO:0006955 immune response
2.69 1.86e-03 GO:0051704 multi-organism process
2.52 3.03e-02 GO:0006952 defense response
2.51 2.78e-04 GO:0002376 immune system process
2.50 3.45e-02 GO:0006508 proteolysis
1.99 2.37e-04 GO:0048522 positive regulation of cellular process
1.89 5.90e-04 GO:0048518 positive regulation of biological process
1.70 4.60e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.33 4.69e-02 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
15.50 1.80e-02 GO:0005839 proteasome core complex
8.61 2.61e-03 GO:0000502 proteasome complex

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
14.76 2.83e-02 GO:0004298 threonine-type endopeptidase activity
14.76 2.83e-02 GO:0070003 threonine-type peptidase activity
2.34 5.15e-03 GO:0001071 nucleic acid binding transcription factor activity
2.34 5.15e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.18 1.16e-02 GO:0005488 binding