Motif ID: PRRX1,2.p2

Z-value: 0.982


Transcription factors associated with PRRX1,2.p2:

Gene SymbolEntrez IDGene Name
PRRX1 5396 paired related homeobox 1
PRRX2 51450 paired related homeobox 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
PRRX2chr9_+_132428016-0.582.3e-03Click!
PRRX1chr1_+_170633312-0.554.1e-03Click!


Activity profile for motif PRRX1,2.p2.

activity profile for motif PRRX1,2.p2


Sorted Z-values histogram for motif PRRX1,2.p2

Sorted Z-values for motif PRRX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PRRX1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_84630575 7.876 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr9_-_14086901 6.849 NFIB
nuclear factor I/B
chr5_-_88119604 5.740 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr15_+_25281105 4.114 SNRPN
small nuclear ribonucleoprotein polypeptide N
chr1_+_84647342 4.034 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_84630014 3.889 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr4_+_41614725 3.578 LIMCH1
LIM and calponin homology domains 1
chr9_-_14398981 3.106 NM_001190738
NFIB
nuclear factor I/B
chr11_+_87032428 3.034 TMEM135
transmembrane protein 135
chr3_-_18480203 2.951 NM_001131010
SATB1
SATB homeobox 1
chr8_-_17555158 2.942 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr5_-_88199868 2.757 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr5_-_88179278 2.649 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr1_+_84630374 2.647 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr13_+_36050885 2.616 NM_001204197
NBEA
neurobeachin
chr4_+_41540187 2.522 LIMCH1
LIM and calponin homology domains 1
chr17_-_67138013 2.518 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr2_-_188312872 2.479 NM_005795
CALCRL
calcitonin receptor-like
chr18_-_53089722 2.470 NM_001243233
TCF4
transcription factor 4
chr7_+_115863004 2.409 NM_152829
TES
testis derived transcript (3 LIM domains)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.14 2.23e-02 GO:0044260 cellular macromolecule metabolic process
1.07 8.89e-05 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
1.30 8.17e-03 GO:0005783 endoplasmic reticulum
1.11 6.55e-03 GO:0044422 organelle part
1.11 1.01e-02 GO:0044446 intracellular organelle part
1.10 3.13e-05 GO:0005737 cytoplasm
1.10 2.05e-02 GO:0005634 nucleus
1.10 3.17e-02 GO:0044444 cytoplasmic part
1.08 1.83e-03 GO:0043231 intracellular membrane-bounded organelle
1.08 2.02e-03 GO:0043227 membrane-bounded organelle
1.07 6.01e-04 GO:0043226 organelle
1.07 7.97e-04 GO:0043229 intracellular organelle
1.06 2.78e-04 GO:0044424 intracellular part
1.06 3.18e-04 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.41 4.28e-03 GO:0005509 calcium ion binding
1.10 1.28e-03 GO:0005515 protein binding