Motif ID: RFX1..5_RFXANK_RFXAP.p2

Z-value: 1.465


Transcription factors associated with RFX1..5_RFXANK_RFXAP.p2:

Gene SymbolEntrez IDGene Name
RFX1 5989 regulatory factor X, 1 (influences HLA class II expression)
RFX2 5990 regulatory factor X, 2 (influences HLA class II expression)
RFX3 5991 regulatory factor X, 3 (influences HLA class II expression)
RFX4 5992 regulatory factor X, 4 (influences HLA class II expression)
RFX5 5993 regulatory factor X, 5 (influences HLA class II expression)
RFXANK 8625 regulatory factor X-associated ankyrin-containing protein
RFXAP 5994 regulatory factor X-associated protein

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
RFX1chr19_-_141170960.501.1e-02Click!
RFX2chr19_-_61104910.386.5e-02Click!
RFX4chr12_+_1069949140.359.0e-02Click!
RFX5chr1_-_151319717-0.281.7e-01Click!
RFX3chr9_-_3525973-0.232.7e-01Click!
RFXANKchr19_+_19303732,
chr19_+_19303007
-0.164.4e-01Click!
RFXAPchr13_+_373933060.106.2e-01Click!


Activity profile for motif RFX1..5_RFXANK_RFXAP.p2.

activity profile for motif RFX1..5_RFXANK_RFXAP.p2


Sorted Z-values histogram for motif RFX1..5_RFXANK_RFXAP.p2

Sorted Z-values for motif RFX1..5_RFXANK_RFXAP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RFX1..5_RFXANK_RFXAP.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_149669187 2.335 CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr5_-_149669400 2.009 NM_015981
NM_171825
CAMK2A

calcium/calmodulin-dependent protein kinase II alpha

chr5_-_179780314 1.886 NM_005110
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr22_+_23487512 1.639 NM_004914
RAB36
RAB36, member RAS oncogene family
chr3_-_123339423 1.550 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr19_-_10679328 1.503 CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr7_-_102715171 1.401 NM_001111038
FBXL13
F-box and leucine-rich repeat protein 13
chr1_-_36915969 1.359 NM_145047
NM_206837
OSCP1

organic solute carrier partner 1

chr13_-_44361032 1.299 NM_001242863
NM_017993
ENOX1

ecto-NOX disulfide-thiol exchanger 1

chr1_-_159869897 1.298 NM_012337
CCDC19
coiled-coil domain containing 19
chr14_-_24657986 1.266 IPO4
importin 4
chr8_+_13424351 1.245 NM_001007090
C8orf48
chromosome 8 open reading frame 48
chr3_+_154797435 1.228 NM_000902
MME
membrane metallo-endopeptidase
chr14_-_24658010 1.197 NM_024658
IPO4
importin 4
chr6_-_112408636 1.179 NM_016262
TUBE1
tubulin, epsilon 1
chr3_-_58563070 1.155 FAM107A
family with sequence similarity 107, member A
chr11_+_8060179 1.152 NM_003320
TUB
tubby homolog (mouse)
chr3_-_123339178 1.133 MYLK
myosin light chain kinase
chr16_+_57050985 1.103 NM_032206
NLRC5
NLR family, CARD domain containing 5
chr6_+_109762204 1.080 SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
2.50 1.29e-02 GO:0007017 microtubule-based process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
7.06 5.27e-06 GO:0035085 cilium axoneme
6.91 1.35e-08 GO:0005930 axoneme
5.69 7.46e-04 GO:0005932 microtubule basal body
5.56 5.39e-06 GO:0044441 cilium part
4.84 1.02e-02 GO:0019861 flagellum
4.07 1.62e-08 GO:0005929 cilium
3.32 2.61e-02 GO:0005875 microtubule associated complex
3.11 1.06e-07 GO:0005874 microtubule
2.61 2.36e-05 GO:0005815 microtubule organizing center
2.54 6.46e-03 GO:0005813 centrosome
2.38 9.74e-09 GO:0015630 microtubule cytoskeleton
2.06 1.31e-02 GO:0044463 cell projection part
1.65 5.34e-03 GO:0044430 cytoskeletal part
1.55 2.57e-03 GO:0005856 cytoskeleton
1.33 3.60e-02 GO:0043228 non-membrane-bounded organelle
1.33 3.60e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.24 3.37e-03 GO:0044422 organelle part
1.23 1.08e-02 GO:0044446 intracellular organelle part
1.18 8.35e-04 GO:0005737 cytoplasm
1.14 8.69e-03 GO:0043226 organelle

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
5.99 4.62e-02 GO:0003887 DNA-directed DNA polymerase activity
3.06 4.49e-02 GO:0016779 nucleotidyltransferase activity