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• Activity deltas table
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Motif ID: RREB1.p2

Z-value: 1.490

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr21_+_27011766	2.423		JAM2	junctional adhesion molecule 2
chrX_+_151903218	2.368	NM_001102576 NM_153478	CSAG1	chondrosarcoma associated gene 1
chr21_+_27012067	2.334		JAM2	junctional adhesion molecule 2
chr6_-_29595746	2.291		GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr11_-_72353435	2.288	NM_001143839 NM_001243784	PDE2A	phosphodiesterase 2A, cGMP-stimulated
chr10_+_115438934	2.184	NM_033340	CASP7	caspase 7, apoptosis-related cysteine peptidase
chr3_+_122399665	2.138	NM_017554	PARP14	poly (ADP-ribose) polymerase family, member 14
chr11_-_134281725	2.035	NM_018644 NM_054025	B3GAT1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr1_+_955468	1.990	NM_198576	AGRN	agrin
chr20_+_48599511	1.874	NM_005985	SNAI1	snail homolog 1 (Drosophila)
chr16_-_3285359	1.873	NM_001145448 NM_198088 NM_001145446 NM_198087	ZNF200	zinc finger protein 200
chr16_-_65155965	1.654		CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)
chr6_+_44095357	1.597	NM_018426	TMEM63B	transmembrane protein 63B
chr7_+_21468293	1.594
chr16_-_65155984	1.576		CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)
chr6_-_32806545	1.563	NM_000544 NM_018833	TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr21_+_27011588	1.513	NM_021219	JAM2	junctional adhesion molecule 2
chr21_+_27012045	1.498		JAM2	junctional adhesion molecule 2
chr1_+_955609	1.497		AGRN	agrin
chr6_+_4776826	1.491		CDYL	chromodomain protein, Y-like
chr9_+_72658735	1.484		MAMDC2	MAM domain containing 2
chrX_-_151903100	1.393	NM_001166386 NM_001166387 NM_005367	MAGEA12	melanoma antigen family A, 12
chr9_+_116918230	1.387	NM_032888	COL27A1	collagen, type XXVII, alpha 1
chr11_-_8739398	1.375		ST5	suppression of tumorigenicity 5
chr11_-_441995	1.362	NM_001012302	ANO9	anoctamin 9
chr15_-_23086290	1.319	NM_144599	NIPA1	non imprinted in Prader-Willi/Angelman syndrome 1
chr6_-_32806452	1.291		TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr1_-_120612301	1.285	NM_001200001 NM_024408	NOTCH2	notch 2
chr11_-_441956	1.263		ANO9	anoctamin 9
chr4_-_5890142	1.240		CRMP1	collapsin response mediator protein 1
chr1_-_205782135	1.230	NM_173854	SLC41A1	solute carrier family 41, member 1
chr4_-_5890266	1.159	NM_001313	CRMP1	collapsin response mediator protein 1
chr11_+_69455978	1.149		CCND1	cyclin D1
chr19_-_55658310	1.128		TNNT1	troponin T type 1 (skeletal, slow)
chr13_-_102068705	1.093	NM_052867	NALCN	sodium leak channel, non-selective
chrY_-_1281526	1.086	NM_001012288 NM_022148	CRLF2	cytokine receptor-like factor 2
chr14_+_105173953	1.082		INF2	inverted formin, FH2 and WH2 domain containing
chr19_-_30205962	1.078	NM_001031726	C19orf12	chromosome 19 open reading frame 12
chrX_-_1331526	1.055	NM_001012288 NM_022148	CRLF2	cytokine receptor-like factor 2
chr13_+_100633977	1.038	NM_007129	ZIC2	Zic family member 2
chr19_+_55795533	1.030	NM_032430	BRSK1	BR serine/threonine kinase 1
chr1_-_200992824	1.007	NM_001252100 NM_001252102 NM_001252103 NM_017596	KIF21B	kinesin family member 21B
chr6_-_6320897	0.988	NM_000129	F13A1	coagulation factor XIII, A1 polypeptide
chr22_+_39853534	0.988		MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr11_+_67183144	0.984	NM_001166222 NM_020811	CARNS1	carnosine synthase 1
chr12_+_102271082	0.974	NM_018370	DRAM1	DNA-damage regulated autophagy modulator 1
chr11_-_1016736	0.965		MUC6	mucin 6, oligomeric mucus/gel-forming
chr17_-_7991020	0.963	NM_001139	ALOX12B	arachidonate 12-lipoxygenase, 12R type
chr12_+_50479033	0.962		SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr17_-_27278471	0.954	NM_001033561 NM_020889	PHF12	PHD finger protein 12
chr6_-_6320875	0.940		F13A1	coagulation factor XIII, A1 polypeptide
chr16_-_65155881	0.940	NM_001797	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)
chr1_-_41131113	0.939		RIMS3	regulating synaptic membrane exocytosis 3
chr11_-_4414887	0.918	NM_003141	TRIM21	tripartite motif containing 21
chr8_+_145064583	0.916		GRINA	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr17_-_40264687	0.910	NM_024119	DHX58	DEXH (Asp-Glu-X-His) box polypeptide 58
chr19_-_47249682	0.901		STRN4	striatin, calmodulin binding protein 4
chr4_+_142557722	0.898	NM_000585 NM_172175	IL15	interleukin 15
chr1_-_41131323	0.895	NM_014747	RIMS3	regulating synaptic membrane exocytosis 3
chr1_+_955536	0.894
chr21_+_44073650	0.894	NM_001001567 NM_001001568 NM_001001569 NM_001001570 NM_001001571 NM_001001572 NM_001001573 NM_001001574 NM_001001575 NM_001001576 NM_001001577 NM_001001578 NM_001001579 NM_001001580 NM_001001581 NM_001001582 NM_001001583 NM_001001584 NM_001001585 NM_002606	PDE9A	phosphodiesterase 9A
chr8_+_145064238	0.891		GRINA	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr10_-_49812996	0.891	NM_021226	ARHGAP22	Rho GTPase activating protein 22
chr22_-_32599463	0.888	NM_001098527	RFPL2	ret finger protein-like 2
chr16_+_1203240	0.879	NM_001005407 NM_021098	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr19_-_17958773	0.873		JAK3	Janus kinase 3
chr19_-_47249629	0.865		STRN4	striatin, calmodulin binding protein 4
chr19_+_44084695	0.861	NM_001193622	LOC390940	uncharacterized protein ENSP00000244321
chr19_+_44084758	0.855		LOC390940	uncharacterized protein ENSP00000244321
chr12_+_102271349	0.854		DRAM1	DNA-damage regulated autophagy modulator 1
chr17_+_46985853	0.847		UBE2Z	ubiquitin-conjugating enzyme E2Z
chr6_-_32806009	0.841		TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr19_+_18284578	0.840	NM_006332	IFI30	interferon, gamma-inducible protein 30
chr3_+_5021096	0.836	NM_003670	BHLHE40	basic helix-loop-helix family, member e40
chr18_+_43914186	0.822	NM_152470	RNF165-IT1 RNF165	RNF165 intronic transcript 1 (non-protein coding) ring finger protein 165
chr1_+_145209067	0.817	NM_203458	NOTCH2NL	notch 2 N-terminal like
chr12_+_50478942	0.801	NM_003076 NM_139071	SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr2_+_219745243	0.794	NM_025216	WNT10A	wingless-type MMTV integration site family, member 10A
chr3_-_10547267	0.793	NM_001001331 NM_001683	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
chr15_-_23086842	0.793	NM_001142275	NIPA1	non imprinted in Prader-Willi/Angelman syndrome 1
chr4_-_109089444	0.790	NM_001130713 NM_001130714 NM_016269	LEF1	lymphoid enhancer-binding factor 1
chr8_+_17354562	0.785	NM_001008539	SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr5_+_6448735	0.776	NM_001145161	UBE2QL1	ubiquitin-conjugating enzyme E2Q family-like 1
chr12_-_133306531	0.764		ANKLE2	ankyrin repeat and LEM domain containing 2
chr19_+_3880617	0.761	NM_033064	ATCAY	ataxia, cerebellar, Cayman type
chr11_-_75062650	0.757	NM_004041 NM_020251	ARRB1	arrestin, beta 1
chr17_-_37307888	0.756	NM_020405	PLXDC1	plexin domain containing 1
chr1_-_120612175	0.754		NOTCH2	notch 2
chr19_-_47975074	0.749		SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2
chr19_-_55660557	0.745	NM_001126132 NM_001126133 NM_003283	TNNT1	troponin T type 1 (skeletal, slow)
chr14_-_24047428	0.744		JPH4	junctophilin 4
chr9_-_124262035	0.743		GGTA1P	glycoprotein, alpha-galactosyltransferase 1 pseudogene
chr19_+_13134782	0.742		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr10_+_24497719	0.741	NM_001098501 NM_019590	KIAA1217	KIAA1217
chr17_-_1733083	0.731	NM_052928	SMYD4	SET and MYND domain containing 4
chr16_+_50186809	0.729	NM_001040284 NM_001040285	PAPD5	PAP associated domain containing 5
chr12_-_50101192	0.726	NM_175736 NM_198900	FMNL3	formin-like 3
chr2_+_73144603	0.726	NM_004097	EMX1	empty spiracles homeobox 1
chr11_+_66742747	0.723	NM_001136485	C11orf86	chromosome 11 open reading frame 86
chr5_-_142065586	0.714	NM_000800	FGF1	fibroblast growth factor 1 (acidic)
chr11_+_57228126	0.714	NM_178570	RTN4RL2	reticulon 4 receptor-like 2
chr1_+_155108276	0.713	NM_001122837 NM_001122839 NM_018845	SLC50A1	solute carrier family 50 (sugar transporter), member 1
chr5_-_172756505	0.708	NM_003714	STC2	stanniocalcin 2
chr3_-_71632741	0.702	NM_001244808 NM_001012505 NM_001244810 NM_032682	FOXP1	forkhead box P1
chr8_+_58906968	0.701	NM_147189	FAM110B	family with sequence similarity 110, member B
chr19_+_55795766	0.698		BRSK1	BR serine/threonine kinase 1
chr7_+_143058794	0.694		ZYX	zyxin
chr21_+_43639930	0.693	NM_207174	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr19_-_47249708	0.693	NM_001039877 NM_013403	STRN4	striatin, calmodulin binding protein 4
chr14_-_21566497	0.689		ZNF219	zinc finger protein 219
chr17_-_4167028	0.685	NM_016376 NM_020740	ANKFY1	ankyrin repeat and FYVE domain containing 1
chr16_+_2039945	0.683	NM_004209	SYNGR3	synaptogyrin 3
chr1_-_202612580	0.683	NM_001136504	SYT2	synaptotagmin II
chr17_-_33700619	0.682	NM_001104587 NM_001104588 NM_001104589 NM_001104590 NM_152270	SLFN11	schlafen family member 11
chr7_-_100493481	0.681	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr1_+_1076275	0.678		LOC254099	uncharacterized LOC254099
chr19_-_344778	0.674	NM_017550	MIER2	mesoderm induction early response 1, family member 2
chr2_-_225907312	0.674	NM_014689	DOCK10	dedicator of cytokinesis 10
chr2_-_100720934	0.670		AFF3	AF4/FMR2 family, member 3
chr2_+_233734993	0.668	NM_206895	C2orf82	chromosome 2 open reading frame 82
chr16_+_30675777	0.660	NM_001105079	FBRS	fibrosin
chr16_+_30676098	0.659		FBRS	fibrosin
chr12_+_54378929	0.657	NM_017409	HOXC10	homeobox C10
chr1_+_155108343	0.654		SLC50A1	solute carrier family 50 (sugar transporter), member 1
chr6_-_46459010	0.649	NM_001251974	RCAN2	regulator of calcineurin 2
chr16_-_3285069	0.642	NM_001145447 NM_003454	ZNF200	zinc finger protein 200
chr6_-_30654406	0.641		PPP1R18	protein phosphatase 1, regulatory subunit 18
chr3_+_31574119	0.637		STT3B	STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr7_-_108096693	0.636	NM_001193582 NM_001193583 NM_001193584 NM_005010	NRCAM	neuronal cell adhesion molecule
chr19_-_47975244	0.635	NM_015063	SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2
chr16_-_67970734	0.633	NM_002801	PSMB10	proteasome (prosome, macropain) subunit, beta type, 10
chr8_+_145064167	0.633	NM_000837 NM_001009184	GRINA	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr11_+_61722606	0.632		BEST1	bestrophin 1
chr2_-_100758970	0.630	NM_002285	AFF3	AF4/FMR2 family, member 3
chr12_-_16758312	0.624	NM_001243611	LMO3	LIM domain only 3 (rhombotin-like 2)
chr16_+_28834372	0.624		ATXN2L	ataxin 2-like
chr1_-_236030170	0.623
chr7_-_98467663	0.622	NM_001134450 NM_001134451 NM_152913	TMEM130	transmembrane protein 130
chr3_+_5021141	0.621		BHLHE40	basic helix-loop-helix family, member e40
chr6_+_4776641	0.616	NM_004824	CDYL	chromodomain protein, Y-like
chr6_-_32805819	0.613		TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr11_-_125933186	0.607	NM_001243597 NM_016952	CDON	Cdon homolog (mouse)
chr2_-_97560855	0.606	NM_001172667	FAM178B	family with sequence similarity 178, member B
chr20_+_45523247	0.606	NM_005244 NM_172110	EYA2	eyes absent homolog 2 (Drosophila)
chr2_-_224903933	0.605	NM_001136528 NM_006216	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr9_+_132934685	0.601	NM_014286	NCS1	neuronal calcium sensor 1
chr9_+_130565528	0.599		FPGS	folylpolyglutamate synthase
chr7_-_139477437	0.596	NM_001113239 NM_022740	HIPK2	homeodomain interacting protein kinase 2
chr7_-_92465929	0.596	NM_001145306	CDK6	cyclin-dependent kinase 6
chr11_-_34379526	0.594	NM_145804	ABTB2	ankyrin repeat and BTB (POZ) domain containing 2
chr16_+_28834407	0.593	NM_007245 NM_145714 NM_148414 NM_148415 NM_148416	ATXN2L	ataxin 2-like
chr20_-_44144263	0.587	NM_006652	SPINT3	serine peptidase inhibitor, Kunitz type, 3
chr9_+_132427919	0.585	NM_016307	PRRX2	paired related homeobox 2
chr3_+_129612702	0.583		LOC100507032	uncharacterized LOC100507032
chr12_-_49504337	0.581		LMBR1L	limb region 1 homolog (mouse)-like
chr11_-_79151694	0.579	NM_001098816	ODZ4	odz, odd Oz/ten-m homolog 4 (Drosophila)
chr14_-_24615794	0.579	NM_002818	PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr16_+_28834360	0.579		ATXN2L	ataxin 2-like
chr17_-_37353731	0.578	NM_000723 NM_199247 NM_199248	CACNB1	calcium channel, voltage-dependent, beta 1 subunit
chr6_-_160114318	0.576	NM_000636 NM_001024465 NM_001024466	SOD2	superoxide dismutase 2, mitochondrial
chr17_+_46985829	0.574		UBE2Z	ubiquitin-conjugating enzyme E2Z
chr2_-_31352489	0.572	NM_001253827	GALNT14	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr16_-_67970651	0.567		PSMB10	proteasome (prosome, macropain) subunit, beta type, 10
chr21_-_44495894	0.560	NM_000071	CBS	cystathionine-beta-synthase
chr21_+_45161343	0.559		PDXK	pyridoxal (pyridoxine, vitamin B6) kinase
chr14_+_29236171	0.557	NM_005249	FOXG1	forkhead box G1
chr4_-_819879	0.556	NM_006651	CPLX1	complexin 1
chr11_-_77184549	0.555	NM_001128620 NM_002576	PAK1	p21 protein (Cdc42/Rac)-activated kinase 1
chr17_-_27278324	0.551		PHF12	PHD finger protein 12
chr4_+_4543718	0.550		LOC100507266	uncharacterized LOC100507266
chr4_-_120549827	0.547	NM_001083	PDE5A	phosphodiesterase 5A, cGMP-specific
chr9_+_130565454	0.547	NM_001018078	FPGS	folylpolyglutamate synthase
chr6_+_7107799	0.547	NM_001168344	RREB1	ras responsive element binding protein 1
chr12_-_49504612	0.546		LMBR1L	limb region 1 homolog (mouse)-like
chr4_-_185395616	0.541	NM_002199	IRF2	interferon regulatory factor 2
chr1_+_233749749	0.541	NM_002245	KCNK1	potassium channel, subfamily K, member 1
chr2_+_154728424	0.538	NM_052917	GALNT13	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr5_-_133304274	0.536	NM_020199	C5orf15	chromosome 5 open reading frame 15
chr20_-_41818464	0.536	NM_007050 NM_133170	PTPRT	protein tyrosine phosphatase, receptor type, T
chr9_+_72658496	0.535	NM_153267	MAMDC2	MAM domain containing 2
chr15_+_74422920	0.533		ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2
chrX_+_154611748	0.530	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated 2 coagulation factor VIII-associated 3 coagulation factor VIII-associated 1
chr15_+_76629101	0.529	NM_145805	ISL2	ISL LIM homeobox 2
chr15_+_74422742	0.529	NM_020851	ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2
chr12_-_49504646	0.528	NM_018113	LMBR1L	limb region 1 homolog (mouse)-like
chr17_-_41622727	0.522		ETV4	ets variant 4
chr16_+_30210548	0.521	NM_001017390 NM_177552	SULT1A4 SULT1A3	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr20_+_35974458	0.520	NM_198291	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr6_+_7107986	0.520	NM_001003698 NM_001003699 NM_001003700	RREB1	ras responsive element binding protein 1
chr14_+_70078313	0.519		KIAA0247	KIAA0247
chr19_+_44080951	0.518	NM_001193621	LOC390940	uncharacterized protein ENSP00000244321
chrX_+_154114609	0.518	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated 2 coagulation factor VIII-associated 3 coagulation factor VIII-associated 1
chr9_-_21994414	0.517	NM_058195	CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr2_-_264742	0.514		SH3YL1	SH3 domain containing, Ysc84-like 1 (S. cerevisiae)
chrX_-_153881757	0.514	NM_020994 NM_172377	CTAG2	cancer/testis antigen 2
chr11_+_369723	0.510	NM_178537	B4GALNT4	beta-1,4-N-acetyl-galactosaminyl transferase 4
chr13_-_114018365	0.507	NM_024719	GRTP1	growth hormone regulated TBC protein 1
chr16_+_89778242	0.506		LOC100128881	uncharacterized LOC100128881
chr9_-_21994379	0.502		CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr18_-_19748928	0.497		LOC100128893	uncharacterized LOC100128893

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.18	2.59e-20	GO:0065007	biological regulation
1.55	2.25e-19	GO:0007399	nervous system development
1.18	1.34e-17	GO:0050789	regulation of biological process
1.33	1.07e-16	GO:0048856	anatomical structure development
1.31	1.27e-16	GO:0007275	multicellular organismal development
1.35	2.07e-16	GO:0048731	system development
1.18	4.29e-16	GO:0050794	regulation of cellular process
1.41	1.89e-15	GO:0030154	cell differentiation
1.28	3.73e-15	GO:0032502	developmental process
1.28	9.08e-15	GO:0023052	signaling
1.45	1.53e-14	GO:0023051	regulation of signaling
1.59	1.73e-14	GO:0007154	cell communication
1.39	2.18e-14	GO:0048869	cellular developmental process
1.62	4.32e-14	GO:0048468	cell development
1.71	6.26e-14	GO:0030182	neuron differentiation
1.59	9.11e-14	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.62	4.29e-13	GO:0048699	generation of neurons
1.59	7.71e-13	GO:0022008	neurogenesis
1.64	5.31e-12	GO:0007267	cell-cell signaling
1.31	6.43e-12	GO:0048518	positive regulation of biological process
1.44	1.74e-11	GO:0009966	regulation of signal transduction
1.43	3.02e-11	GO:0009653	anatomical structure morphogenesis
1.55	7.21e-11	GO:0050793	regulation of developmental process
1.45	8.32e-11	GO:0051239	regulation of multicellular organismal process
1.64	1.10e-10	GO:0010628	positive regulation of gene expression
1.36	1.35e-10	GO:0048583	regulation of response to stimulus
1.32	2.21e-10	GO:0048519	negative regulation of biological process
1.37	3.18e-10	GO:0007166	cell surface receptor linked signaling pathway
1.49	3.84e-10	GO:0010646	regulation of cell communication
1.63	4.55e-10	GO:0045595	regulation of cell differentiation
1.79	4.60e-10	GO:0007268	synaptic transmission
1.74	5.06e-10	GO:0019226	transmission of nerve impulse
1.74	5.06e-10	GO:0035637	multicellular organismal signaling
1.25	5.33e-10	GO:0007165	signal transduction
1.30	7.87e-10	GO:0048522	positive regulation of cellular process
1.32	8.37e-10	GO:0048523	negative regulation of cellular process
1.09	1.06e-09	GO:0009987	cellular process
1.57	2.26e-09	GO:2000026	regulation of multicellular organismal development
1.23	3.81e-09	GO:0031323	regulation of cellular metabolic process
1.22	6.02e-09	GO:0019222	regulation of metabolic process
1.70	6.57e-09	GO:0000904	cell morphogenesis involved in differentiation
1.64	1.45e-08	GO:0048666	neuron development
1.68	1.48e-08	GO:0007417	central nervous system development
1.23	1.75e-08	GO:0080090	regulation of primary metabolic process
1.33	1.94e-08	GO:0048513	organ development
1.43	2.08e-08	GO:0010604	positive regulation of macromolecule metabolic process
1.60	2.78e-08	GO:0045893	positive regulation of transcription, DNA-dependent
1.20	2.90e-08	GO:0051716	cellular response to stimulus
1.41	3.29e-08	GO:0009893	positive regulation of metabolic process
1.58	3.45e-08	GO:0051254	positive regulation of RNA metabolic process
1.78	6.65e-08	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.71	9.81e-08	GO:0032583	regulation of gene-specific transcription
1.46	1.09e-07	GO:0032879	regulation of localization
1.70	1.20e-07	GO:0048667	cell morphogenesis involved in neuron differentiation
1.71	1.53e-07	GO:0007409	axonogenesis
1.65	2.05e-07	GO:0031175	neuron projection development
1.25	2.17e-07	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.69	2.23e-07	GO:0048812	neuron projection morphogenesis
1.51	4.10e-07	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.51	4.26e-07	GO:0010557	positive regulation of macromolecule biosynthetic process
1.71	4.69e-07	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.22	4.69e-07	GO:0060255	regulation of macromolecule metabolic process
1.24	5.96e-07	GO:0051171	regulation of nitrogen compound metabolic process
1.65	6.47e-07	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.46	9.66e-07	GO:0009888	tissue development
1.16	9.71e-07	GO:0032501	multicellular organismal process
1.73	1.07e-06	GO:0007420	brain development
1.60	1.09e-06	GO:0045892	negative regulation of transcription, DNA-dependent
1.27	1.31e-06	GO:0042221	response to chemical stimulus
1.59	1.54e-06	GO:0051253	negative regulation of RNA metabolic process
1.38	1.74e-06	GO:0031325	positive regulation of cellular metabolic process
1.48	2.38e-06	GO:0051173	positive regulation of nitrogen compound metabolic process
1.45	2.94e-06	GO:0009891	positive regulation of biosynthetic process
1.76	3.09e-06	GO:0060284	regulation of cell development
1.53	3.26e-06	GO:0032989	cellular component morphogenesis
1.26	3.39e-06	GO:0051252	regulation of RNA metabolic process
2.23	3.50e-06	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.24	4.22e-06	GO:0010468	regulation of gene expression
1.81	4.87e-06	GO:0051960	regulation of nervous system development
2.21	5.04e-06	GO:0022604	regulation of cell morphogenesis
1.41	5.36e-06	GO:0009605	response to external stimulus
1.44	7.93e-06	GO:0031328	positive regulation of cellular biosynthetic process
2.01	9.01e-06	GO:0030900	forebrain development
1.53	9.86e-06	GO:0000902	cell morphogenesis
1.95	1.07e-05	GO:0032582	negative regulation of gene-specific transcription
1.32	1.37e-05	GO:0065009	regulation of molecular function
1.50	1.86e-05	GO:0030030	cell projection organization
1.73	2.42e-05	GO:0022603	regulation of anatomical structure morphogenesis
1.48	2.45e-05	GO:0031327	negative regulation of cellular biosynthetic process
1.60	2.56e-05	GO:0051094	positive regulation of developmental process
1.79	3.07e-05	GO:0045596	negative regulation of cell differentiation
1.56	3.68e-05	GO:0048585	negative regulation of response to stimulus
1.25	4.10e-05	GO:0006355	regulation of transcription, DNA-dependent
1.51	4.22e-05	GO:0010629	negative regulation of gene expression
1.56	4.30e-05	GO:0048858	cell projection morphogenesis
1.47	4.57e-05	GO:0009890	negative regulation of biosynthetic process
2.01	4.79e-05	GO:0010553	negative regulation of gene-specific transcription from RNA polymerase II promoter
1.69	5.01e-05	GO:0051093	negative regulation of developmental process
1.49	6.05e-05	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
3.26	6.85e-05	GO:0033135	regulation of peptidyl-serine phosphorylation
1.48	7.16e-05	GO:0010558	negative regulation of macromolecule biosynthetic process
1.22	7.27e-05	GO:0009889	regulation of biosynthetic process
1.22	7.65e-05	GO:0031326	regulation of cellular biosynthetic process
1.54	7.94e-05	GO:0032990	cell part morphogenesis
3.54	8.34e-05	GO:0033138	positive regulation of peptidyl-serine phosphorylation
1.50	8.69e-05	GO:0009887	organ morphogenesis
1.54	9.27e-05	GO:0009967	positive regulation of signal transduction
1.39	1.03e-04	GO:0070887	cellular response to chemical stimulus
1.57	1.29e-04	GO:0023057	negative regulation of signaling
1.40	1.38e-04	GO:0040011	locomotion
1.57	1.51e-04	GO:0010648	negative regulation of cell communication
1.77	1.53e-04	GO:0050767	regulation of neurogenesis
1.47	1.86e-04	GO:0051172	negative regulation of nitrogen compound metabolic process
1.51	1.86e-04	GO:0023056	positive regulation of signaling
1.51	2.17e-04	GO:0010647	positive regulation of cell communication
1.47	2.20e-04	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.64	2.37e-04	GO:0007389	pattern specification process
2.44	2.88e-04	GO:0048638	regulation of developmental growth
1.77	3.04e-04	GO:0003002	regionalization
1.22	3.35e-04	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.40	3.51e-04	GO:0048584	positive regulation of response to stimulus
1.64	3.82e-04	GO:0007411	axon guidance
1.57	3.86e-04	GO:0009968	negative regulation of signal transduction
1.38	4.22e-04	GO:0031324	negative regulation of cellular metabolic process
1.63	4.56e-04	GO:0045597	positive regulation of cell differentiation
1.63	5.45e-04	GO:0044057	regulation of system process
1.84	6.31e-04	GO:0043408	regulation of MAPKKK cascade
1.39	7.35e-04	GO:0044093	positive regulation of molecular function
1.21	9.45e-04	GO:0010556	regulation of macromolecule biosynthetic process
1.36	1.07e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.43	1.18e-03	GO:0071310	cellular response to organic substance
1.66	1.22e-03	GO:0007423	sensory organ development
1.49	1.24e-03	GO:0006935	chemotaxis
1.49	1.24e-03	GO:0042330	taxis
1.40	1.39e-03	GO:0051049	regulation of transport
1.22	1.51e-03	GO:0065008	regulation of biological quality
1.34	1.77e-03	GO:0009892	negative regulation of metabolic process
1.41	1.89e-03	GO:0009790	embryo development
1.75	2.05e-03	GO:0043193	positive regulation of gene-specific transcription
1.94	2.11e-03	GO:0016055	Wnt receptor signaling pathway
1.77	2.13e-03	GO:0045664	regulation of neuron differentiation
1.55	2.52e-03	GO:0010627	regulation of intracellular protein kinase cascade
1.11	3.68e-03	GO:0050896	response to stimulus
1.16	4.32e-03	GO:0016043	cellular component organization
1.58	4.67e-03	GO:0051098	regulation of binding
2.04	6.14e-03	GO:0010720	positive regulation of cell development
1.95	7.43e-03	GO:0010959	regulation of metal ion transport
1.59	8.60e-03	GO:0048729	tissue morphogenesis
2.26	9.20e-03	GO:0050770	regulation of axonogenesis
1.59	1.01e-02	GO:0051130	positive regulation of cellular component organization
1.84	1.10e-02	GO:0045165	cell fate commitment
1.33	1.26e-02	GO:0006351	transcription, DNA-dependent
1.82	1.77e-02	GO:0031344	regulation of cell projection organization
1.88	1.84e-02	GO:0030111	regulation of Wnt receptor signaling pathway
2.00	1.96e-02	GO:0043410	positive regulation of MAPKKK cascade
1.86	2.36e-02	GO:0042391	regulation of membrane potential
1.89	2.48e-02	GO:0010975	regulation of neuron projection development
1.33	2.60e-02	GO:0051128	regulation of cellular component organization
1.57	2.63e-02	GO:0051270	regulation of cellular component movement
1.15	2.65e-02	GO:0071840	cellular component organization or biogenesis
3.15	2.66e-02	GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway
1.45	2.72e-02	GO:0008283	cell proliferation
1.17	3.11e-02	GO:0071842	cellular component organization at cellular level
2.52	3.28e-02	GO:0048663	neuron fate commitment
1.96	3.47e-02	GO:0051924	regulation of calcium ion transport
1.25	3.68e-02	GO:0035556	intracellular signal transduction
1.64	3.74e-02	GO:0071375	cellular response to peptide hormone stimulus
2.01	3.92e-02	GO:0021537	telencephalon development
1.37	4.00e-02	GO:0001932	regulation of protein phosphorylation
1.35	4.69e-02	GO:0043085	positive regulation of catalytic activity
2.09	4.79e-02	GO:0021953	central nervous system neuron differentiation
1.36	4.96e-02	GO:0007167	enzyme linked receptor protein signaling pathway

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.31	4.50e-10	GO:0044459	plasma membrane part
1.71	1.66e-08	GO:0045202	synapse
1.82	4.49e-08	GO:0044456	synapse part
1.52	1.18e-06	GO:0030054	cell junction
1.56	1.48e-04	GO:0031012	extracellular matrix
1.54	1.99e-04	GO:0043005	neuron projection
1.29	1.08e-03	GO:0000267	cell fraction
1.11	1.81e-03	GO:0005634	nucleus
1.67	2.29e-03	GO:0034702	ion channel complex
1.80	2.44e-03	GO:0045211	postsynaptic membrane
1.32	2.79e-03	GO:0042995	cell projection
1.13	3.14e-03	GO:0005886	plasma membrane
1.83	3.60e-03	GO:0034703	cation channel complex
1.53	3.85e-03	GO:0005578	proteinaceous extracellular matrix
1.12	5.35e-03	GO:0071944	cell periphery
2.02	5.72e-03	GO:0008021	synaptic vesicle
1.30	1.12e-02	GO:0005626	insoluble fraction
1.31	1.20e-02	GO:0031982	vesicle
1.30	1.28e-02	GO:0005624	membrane fraction
2.78	1.53e-02	GO:0034704	calcium channel complex
3.12	1.68e-02	GO:0005891	voltage-gated calcium channel complex
1.30	2.17e-02	GO:0031410	cytoplasmic vesicle
1.31	2.39e-02	GO:0016023	cytoplasmic membrane-bounded vesicle
1.23	2.69e-02	GO:0031226	intrinsic to plasma membrane
1.23	2.84e-02	GO:0005887	integral to plasma membrane
1.30	3.41e-02	GO:0031988	membrane-bounded vesicle
1.42	3.95e-02	GO:0009986	cell surface

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.19	5.14e-21	GO:0005515	protein binding
1.74	6.55e-16	GO:0043565	sequence-specific DNA binding
1.53	4.14e-12	GO:0001071	nucleic acid binding transcription factor activity
1.53	4.14e-12	GO:0003700	sequence-specific DNA binding transcription factor activity
1.44	1.57e-08	GO:0030528	transcription regulator activity
1.07	2.68e-08	GO:0005488	binding
2.02	2.40e-05	GO:0022843	voltage-gated cation channel activity
1.70	8.57e-05	GO:0005261	cation channel activity
1.56	1.14e-04	GO:0022838	substrate-specific channel activity
1.79	1.26e-04	GO:0000975	regulatory region DNA binding
1.79	1.26e-04	GO:0001067	regulatory region nucleic acid binding
1.79	1.26e-04	GO:0044212	transcription regulatory region DNA binding
1.39	2.35e-04	GO:0019899	enzyme binding
1.55	2.90e-04	GO:0005216	ion channel activity
1.61	4.36e-04	GO:0016564	transcription repressor activity
1.32	5.05e-04	GO:0005102	receptor binding
1.61	5.17e-04	GO:0022836	gated channel activity
1.76	5.72e-04	GO:0010843	promoter binding
1.78	6.30e-04	GO:0005244	voltage-gated ion channel activity
1.78	6.30e-04	GO:0022832	voltage-gated channel activity
1.51	6.87e-04	GO:0015267	channel activity
1.51	7.93e-04	GO:0022803	passive transmembrane transporter activity
1.59	8.59e-04	GO:0016563	transcription activator activity
2.10	4.43e-03	GO:0003705	sequence-specific enhancer binding RNA polymerase II transcription factor activity
2.00	8.65e-03	GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
1.18	9.03e-03	GO:0003677	DNA binding
1.33	1.25e-02	GO:0042802	identical protein binding
1.34	2.26e-02	GO:0046983	protein dimerization activity
2.90	2.64e-02	GO:0005245	voltage-gated calcium channel activity
1.84	2.66e-02	GO:0051020	GTPase binding
1.90	3.44e-02	GO:0005249	voltage-gated potassium channel activity
1.54	4.30e-02	GO:0005096	GTPase activator activity
1.30	4.69e-02	GO:0015075	ion transmembrane transporter activity