Motif ID: RXR{A,B,G}.p2

Z-value: 1.179


Transcription factors associated with RXR{A,B,G}.p2:

Gene SymbolEntrez IDGene Name
RXRA 6256 retinoid X receptor, alpha
RXRB 6257 retinoid X receptor, beta
RXRG 6258 retinoid X receptor, gamma

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
RXRAchr9_+_1372183240.491.4e-02Click!
RXRBchr6_-_331684480.252.3e-01Click!
RXRGchr1_-_165414499-0.145.2e-01Click!


Activity profile for motif RXR{A,B,G}.p2.

activity profile for motif RXR{A,B,G}.p2


Sorted Z-values histogram for motif RXR{A,B,G}.p2

Sorted Z-values for motif RXR{A,B,G}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXR{A,B,G}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_35873823 1.965 NM_020529
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr11_+_73087670 1.412 NM_032871
RELT
RELT tumor necrosis factor receptor
chr6_+_14118002 1.405 CD83
CD83 molecule
chr19_-_1174201 1.359


chr19_-_1174263 1.339 NM_014963
SBNO2
strawberry notch homolog 2 (Drosophila)
chr2_+_27301693 1.184 EMILIN1
elastin microfibril interfacer 1
chr4_-_38666429 1.090 FLJ13197
uncharacterized FLJ13197
chr17_+_36861857 1.073 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr12_-_109251333 1.054 NM_001161330
NM_018984
SSH1

slingshot homolog 1 (Drosophila)

chr19_-_50432647 1.051 IL4I1
interleukin 4 induced 1
chr19_-_50432672 1.049 IL4I1
interleukin 4 induced 1
chr19_-_1174257 1.028 SBNO2
strawberry notch homolog 2 (Drosophila)
chr7_+_143078399 0.999 ZYX
zyxin
chr19_+_50354417 0.998 PTOV1
prostate tumor overexpressed 1
chr19_+_10381516 0.977 NM_000201
ICAM1
intercellular adhesion molecule 1
chr19_+_50354368 0.976 NM_017432
PTOV1
prostate tumor overexpressed 1
chr19_+_17830302 0.932 NM_018174
MAP1S
microtubule-associated protein 1S
chr19_+_45251933 0.923 NM_005178
BCL3
B-cell CLL/lymphoma 3
chr9_-_110251308 0.922 KLF4
Kruppel-like factor 4 (gut)
chr9_-_110251754 0.918 KLF4
Kruppel-like factor 4 (gut)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
4.17 8.76e-03 GO:0043535 regulation of blood vessel endothelial cell migration
1.69 3.21e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.60 2.75e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.60 3.13e-03 GO:0010629 negative regulation of gene expression
1.59 1.51e-02 GO:0051253 negative regulation of RNA metabolic process
1.59 2.06e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.58 1.98e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.58 2.45e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.54 5.67e-03 GO:0009890 negative regulation of biosynthetic process
1.53 3.29e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.52 1.93e-02 GO:0010628 positive regulation of gene expression
1.52 3.84e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.51 2.20e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.48 4.03e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.45 4.44e-03 GO:0009892 negative regulation of metabolic process
1.45 1.52e-02 GO:0031324 negative regulation of cellular metabolic process
1.43 5.34e-03 GO:0010646 regulation of cell communication
1.39 1.37e-03 GO:0009966 regulation of signal transduction
1.35 2.50e-03 GO:0023051 regulation of signaling
1.33 1.40e-03 GO:0048583 regulation of response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.11 5.56e-04 GO:0005737 cytoplasm
1.10 2.35e-03 GO:0043231 intracellular membrane-bounded organelle
1.10 2.37e-03 GO:0043227 membrane-bounded organelle
1.08 3.75e-02 GO:0043226 organelle
1.08 3.87e-02 GO:0043229 intracellular organelle
1.07 5.35e-03 GO:0044424 intracellular part
1.07 6.85e-03 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.19 8.54e-11 GO:0005515 protein binding
1.08 1.61e-05 GO:0005488 binding