Motif ID: RXRA_VDR{dimer}.p2

Z-value: 0.827


Transcription factors associated with RXRA_VDR{dimer}.p2:

Gene SymbolEntrez IDGene Name
VDR 7421 vitamin D (1,25- dihydroxyvitamin D3) receptor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
VDRchr12_-_48298765-0.019.5e-01Click!


Activity profile for motif RXRA_VDR{dimer}.p2.

activity profile for motif RXRA_VDR{dimer}.p2


Sorted Z-values histogram for motif RXRA_VDR{dimer}.p2

Sorted Z-values for motif RXRA_VDR{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXRA_VDR{dimer}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_39899749 2.790


chr1_+_100111430 2.583 NM_017734
PALMD
palmdelphin
chr1_+_61869699 1.848 NFIA
nuclear factor I/A
chr7_+_155089614 1.440 INSIG1
insulin induced gene 1
chr17_-_36348585 1.170 NM_001123391
NM_032258
TBC1D3C
TBC1D3
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3
TBC1 domain family, member 3F
chr17_-_34756980 1.168 NM_001123392
TBC1D3C
TBC1D3G
TBC1D3
TBC1D3H
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3
TBC1 domain family, member 3H
chr17_+_36283959 1.165 NM_001123391
NM_032258
TBC1D3C
TBC1D3
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3
TBC1 domain family, member 3F
chr10_+_35484829 1.156 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr17_-_34591958 1.151 NM_001001418
TBC1D3C
TBC1D3G
TBC1 domain family, member 3C
TBC1 domain family, member 3G
chr17_-_34503914 1.138 NM_001001417
TBC1D3B
TBC1D3C
TBC1D3G
TBC1 domain family, member 3B
TBC1 domain family, member 3C
TBC1 domain family, member 3G
chr7_+_155089483 1.060 NM_005542
NM_198336
NM_198337
INSIG1


insulin induced gene 1


chr21_-_35986744 1.055 NM_203417
RCAN1
regulator of calcineurin 1
chr1_+_35258598 1.012 NM_002060
GJA4
gap junction protein, alpha 4, 37kDa
chr8_-_93115453 0.938 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr19_-_14260728 0.875 LPHN1
latrophilin 1
chr3_-_27764197 0.677 EOMES
eomesodermin
chr6_+_39760138 0.675


chr10_-_33623771 0.670 NM_001024628
NM_001024629
NM_001244972
NM_001244973
NM_003873
NRP1




neuropilin 1




chr6_-_68598987 0.590 ERVH-3
endogenous retrovirus group H, member 3
chr6_+_35227478 0.590 NM_003427
ZNF76
zinc finger protein 76
chr6_-_42016383 0.582 CCND3
cyclin D3
chr22_+_50354428 0.561 PIM3
pim-3 oncogene
chr4_+_134073180 0.474 PCDH10
protocadherin 10
chr2_-_27603584 0.471 NM_144631
ZNF513
zinc finger protein 513
chr6_-_32145841 0.464 NM_032741
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr8_-_8239188 0.458 NM_001080826
SGK223
homolog of rat pragma of Rnd2
chr1_-_209979388 0.453 NM_001206696
NM_006147
IRF6

interferon regulatory factor 6

chr11_+_64863700 0.446 C11orf2
chromosome 11 open reading frame 2
chr11_+_64863607 0.437 NM_013265
C11orf2
chromosome 11 open reading frame 2
chr11_+_64863711 0.436 C11orf2
chromosome 11 open reading frame 2
chr6_-_42016609 0.409 NM_001136017
NM_001136126
CCND3

cyclin D3

chr20_+_42193754 0.409 NM_001199264
SGK2
serum/glucocorticoid regulated kinase 2
chr14_-_35873823 0.383 NM_020529
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr17_+_15903107 0.382 TTC19
tetratricopeptide repeat domain 19
chr10_-_33623978 0.374 NRP1
neuropilin 1
chr2_-_27603249 0.366 NM_001201459
ZNF513
zinc finger protein 513
chr2_+_111490149 0.352 NM_001142807
ACOXL
acyl-CoA oxidase-like
chr21_+_46825001 0.343 NM_130445
COL18A1
collagen, type XVIII, alpha 1
chr2_+_238768186 0.313 NM_005855
RAMP1
receptor (G protein-coupled) activity modifying protein 1
chr22_+_45705965 0.310 FAM118A
family with sequence similarity 118, member A
chr22_+_45705766 0.309 NM_017911
FAM118A
family with sequence similarity 118, member A
chr11_+_124609841 0.306 NRGN
neurogranin (protein kinase C substrate, RC3)
chr11_-_790103 0.305 NM_016564
CEND1
cell cycle exit and neuronal differentiation 1
chrX_+_153686620 0.305 NM_017514
PLXNA3
plexin A3
chr17_+_65373574 0.301 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr19_+_56186569 0.296 EPN1
epsin 1
chr9_+_131644780 0.295 NM_001127244
LRRC8A
leucine rich repeat containing 8 family, member A
chr10_+_30723050 0.295 MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr1_-_154474524 0.290 NM_001010846
SHE
Src homology 2 domain containing E
chr19_+_41620336 0.285 NM_000774
CYP2F1
cytochrome P450, family 2, subfamily F, polypeptide 1
chr6_-_91006580 0.284 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr19_-_44008984 0.284 NM_198850
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr3_+_49208979 0.284 NM_173546
KLHDC8B
kelch domain containing 8B
chr19_+_13261272 0.284 NM_004907
IER2
immediate early response 2
chr19_-_42759279 0.271 NM_006494
ERF
Ets2 repressor factor
chr19_+_36630999 0.268 CAPNS1
calpain, small subunit 1
chr22_-_30867944 0.268 NM_174975
SEC14L3
SEC14-like 3 (S. cerevisiae)
chr11_+_76883823 0.263 MYO7A
myosin VIIA
chr19_+_56186426 0.259 NM_001130072
NM_013333
EPN1

epsin 1

chr13_-_53313835 0.257 LECT1
leukocyte cell derived chemotaxin 1
chr19_-_58858900 0.254 A1BG
alpha-1-B glycoprotein
chr13_+_114321469 0.252 NM_002929
GRK1
G protein-coupled receptor kinase 1
chr1_-_154943001 0.245 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr20_+_34680569 0.244 EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr2_+_108905094 0.243 NM_001056
NM_176825
SULT1C2

sulfotransferase family, cytosolic, 1C, member 2

chr4_-_74904329 0.241 NM_002090
CXCL3
chemokine (C-X-C motif) ligand 3
chr13_-_72441312 0.240 NM_004392
NM_080759
NM_080760
DACH1


dachshund homolog 1 (Drosophila)


chr2_+_66666445 0.235 MEIS1
Meis homeobox 1
chr19_+_36631001 0.234 CAPNS1
calpain, small subunit 1
chr11_-_124805896 0.231 HEPACAM
hepatic and glial cell adhesion molecule
chrX_+_153770458 0.227 NM_001099856
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr19_-_42759151 0.225 ERF
Ets2 repressor factor
chr7_-_91764036 0.224 NM_001146152
CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr6_-_91006460 0.224 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr8_+_22437983 0.221 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr2_+_20646831 0.219 NM_004040
RHOB
ras homolog gene family, member B
chr22_+_50624353 0.219 NM_025204
TRABD
TraB domain containing
chr9_-_5833072 0.218 NM_024896
ERMP1
endoplasmic reticulum metallopeptidase 1
chr1_-_33338081 0.217 NM_001171941
FNDC5
fibronectin type III domain containing 5
chr19_+_39936240 0.216 SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr2_-_234474197 0.213 NM_018218
USP40
ubiquitin specific peptidase 40
chr19_+_56186580 0.210 EPN1
epsin 1
chr1_+_44412640 0.209 IPO13
importin 13
chr3_-_49142165 0.206 NM_005051
QARS
glutaminyl-tRNA synthetase
chr16_+_31119730 0.205 BCKDK
branched chain ketoacid dehydrogenase kinase
chr19_-_4559713 0.203 NM_032108
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr3_-_15374082 0.201 NM_004844
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr1_+_25944610 0.201 MAN1C1
mannosidase, alpha, class 1C, member 1
chr14_-_101034261 0.200 NM_001159531
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr1_+_110527701 0.200 AHCYL1
adenosylhomocysteinase-like 1
chr1_+_203764802 0.199 ZC3H11A
zinc finger CCCH-type containing 11A
chr2_+_220462560 0.198 NM_052902
STK11IP
serine/threonine kinase 11 interacting protein
chr19_+_39936275 0.197 NM_003169
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr1_+_154474694 0.197 NM_001098475
NM_182499
TDRD10

tudor domain containing 10

chrX_-_21676416 0.193 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr17_-_7082654 0.193 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr4_+_144434555 0.193 NM_003601
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr18_+_46065367 0.191 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr14_-_34419957 0.191 NM_022073
EGLN3
egl nine homolog 3 (C. elegans)
chr16_+_12070501 0.190 NM_032167
SNX29
sorting nexin 29
chr2_+_70485204 0.190 NM_016297
PCYOX1
prenylcysteine oxidase 1
chr10_+_102732285 0.188 NM_001203244
NM_017893
SEMA4G

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G

chr16_+_31119661 0.188 NM_001122957
NM_005881
BCKDK

branched chain ketoacid dehydrogenase kinase

chr19_+_39936251 0.186 SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr22_+_50624267 0.186 TRABD
TraB domain containing
chr19_-_19007395 0.185 CERS1
ceramide synthase 1
chr19_-_12834628 0.178 NM_001136195
TNPO2
transportin 2
chr18_-_59560303 0.176 NM_173557
RNF152
ring finger protein 152
chr22_-_29784430 0.175 AP1B1
adaptor-related protein complex 1, beta 1 subunit
chr15_+_91428271 0.175 NM_001143783
NM_001143784
FES

feline sarcoma oncogene

chr9_-_5832840 0.175 ERMP1
endoplasmic reticulum metallopeptidase 1
chr21_+_46825291 0.174


chr6_+_30852756 0.172 NM_001202523
DDR1
discoidin domain receptor tyrosine kinase 1
chr17_+_27895738 0.170 NM_138349
TP53I13
tumor protein p53 inducible protein 13
chr4_+_2794811 0.168 SH3BP2
SH3-domain binding protein 2
chr11_-_124806302 0.167 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr19_-_7293876 0.167 NM_000208
NM_001079817
INSR

insulin receptor

chr19_+_1383877 0.166 NM_024407
NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr11_-_74022609 0.165 NM_182904
P4HA3
prolyl 4-hydroxylase, alpha polypeptide III
chr19_+_56186610 0.163 EPN1
epsin 1
chr11_-_63933204 0.161 MACROD1
MACRO domain containing 1
chr16_+_77756388 0.160 NM_001105663
NM_001243657
NM_001243660
NM_001243661
NUDT7



nudix (nucleoside diphosphate linked moiety X)-type motif 7



chr1_-_175712669 0.160 NM_003285
TNR
tenascin R (restrictin, janusin)
chr6_-_132272311 0.160 NM_001901
CTGF
connective tissue growth factor
chr17_+_72462780 0.159 CD300A
CD300a molecule
chr6_+_30852326 0.158 NM_013993
DDR1
discoidin domain receptor tyrosine kinase 1
chr17_-_17740288 0.153 SREBF1
sterol regulatory element binding transcription factor 1
chr19_-_14629227 0.150 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr11_-_117102810 0.149 NM_004716
PCSK7
proprotein convertase subtilisin/kexin type 7
chr12_+_79439432 0.148 NM_001135806
SYT1
synaptotagmin I
chr11_-_63536112 0.148 NM_001144936
C11orf95
chromosome 11 open reading frame 95
chr17_+_27895677 0.147 TP53I13
tumor protein p53 inducible protein 13
chr15_+_83776323 0.147 NM_001144903
NM_023003
TM6SF1

transmembrane 6 superfamily member 1

chr6_+_27215479 0.145 NM_005865
PRSS16
protease, serine, 16 (thymus)
chrX_+_52928408 0.144 NM_001099684
FAM156A
FAM156B
family with sequence similarity 156, member A
family with sequence similarity 156, member B
chr17_+_79935410 0.140 NM_001251888
NM_024083
ASPSCR1

alveolar soft part sarcoma chromosome region, candidate 1

chr1_+_77748286 0.140 NM_012093
AK5
adenylate kinase 5
chr1_+_203764822 0.139 ZC3H11A
zinc finger CCCH-type containing 11A
chr17_-_56609361 0.138 SEPT4
septin 4
chr7_-_38670950 0.132 AMPH
amphiphysin
chr17_+_79935493 0.132 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr9_+_131798899 0.132 FAM73B
family with sequence similarity 73, member B
chr19_-_460995 0.130 NM_012435
SHC2
SHC (Src homology 2 domain containing) transforming protein 2
chr19_+_1383898 0.129 NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr12_+_54393876 0.128 NM_006897
HOXC9
homeobox C9
chr2_-_39664291 0.128 MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr12_-_109251271 0.127 SSH1
slingshot homolog 1 (Drosophila)
chr20_+_43030005 0.127 HNF4A
hepatocyte nuclear factor 4, alpha
chr19_+_36630846 0.126 NM_001003962
NM_001749
CAPNS1

calpain, small subunit 1

chr6_-_2971281 0.125 SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr17_+_78194090 0.124 NM_001166347
NM_001166348
NM_001166349
NM_173626
SLC26A11



solute carrier family 26, member 11



chr19_+_1383904 0.123 NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr11_-_62476976 0.123 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr1_+_226016428 0.122 EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr14_+_58765209 0.119 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr11_+_7535213 0.118 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr19_+_50270068 0.118 NM_014203
NM_130787
AP2A1

adaptor-related protein complex 2, alpha 1 subunit

chr14_+_105780751 0.118 NM_001100913
NM_015197
PACS2

phosphofurin acidic cluster sorting protein 2

chr17_+_65373923 0.117 NM_012417
NM_181671
PITPNC1

phosphatidylinositol transfer protein, cytoplasmic 1

chr19_-_2783225 0.117 SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr11_-_61129352 0.114 CYBASC3
cytochrome b, ascorbate dependent 3
chr16_+_31119748 0.114 BCKDK
branched chain ketoacid dehydrogenase kinase
chr19_-_2783313 0.114 SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr1_+_110527432 0.114 AHCYL1
adenosylhomocysteinase-like 1
chr17_+_65373362 0.113 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr13_+_47127383 0.112 LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr19_+_50270271 0.110 AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr11_-_64084980 0.109 NM_016404
TRMT112
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr1_+_203764750 0.108 NM_014827
ZC3H11A
zinc finger CCCH-type containing 11A
chr7_+_143078457 0.108 ZYX
zyxin
chr7_+_143078358 0.107 NM_001010972
NM_003461
ZYX

zyxin

chr16_+_28889808 0.107 NM_004320
NM_173201
ATP2A1

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

chr11_-_6440631 0.106 NM_145689
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr4_+_144435076 0.105


chr22_+_50528307 0.105 NM_001164104
NM_018995
MOV10L1

Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)

chr16_+_16043206 0.105 NM_004996
NM_019862
NM_019898
NM_019899
NM_019900
ABCC1




ATP-binding cassette, sub-family C (CFTR/MRP), member 1




chr19_+_13056607 0.105 NM_005053
RAD23A
RAD23 homolog A (S. cerevisiae)
chr7_-_122339186 0.105 NM_139175
RNF133
ring finger protein 133
chr19_+_10791025 0.105


chr16_-_67184822 0.105 NM_033309
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr9_+_139249251 0.104 NM_001200003
GPSM1
G-protein signaling modulator 1
chr19_-_2308155 0.104 NM_001101391
LINGO3
leucine rich repeat and Ig domain containing 3
chr1_-_33336289 0.104 NM_001171940
NM_153756
FNDC5

fibronectin type III domain containing 5

chr19_+_13250072 0.103 NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr7_+_143078444 0.101 ZYX
zyxin
chr16_-_10674443 0.101 NM_001424
EMP2
epithelial membrane protein 2
chr11_+_2421983 0.098 TSSC4
tumor suppressing subtransferable candidate 4
chr5_-_168271852 0.097


chr3_-_151987332 0.095 LOC401093
uncharacterized LOC401093
chr1_+_19971865 0.095 NM_001204085
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr20_+_30028410 0.094 NM_153324
DEFB123
defensin, beta 123
chr14_-_93581507 0.093 ITPK1
inositol-tetrakisphosphate 1-kinase
chr3_-_42307661 0.093 NM_000729
CCK
cholecystokinin
chr12_+_53895376 0.092 NM_134324
TARBP2
TAR (HIV-1) RNA binding protein 2
chr10_+_80899458 0.091 ZMIZ1
zinc finger, MIZ-type containing 1
chr6_-_7910278 0.090 NM_001145549
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr5_-_32174397 0.090 NM_022130
GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr5_-_32174355 0.089 GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr19_+_39936220 0.089 SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr6_-_7910716 0.088 NM_030810
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.78 1.40e-02 GO:0005099 Ras GTPase activator activity
6.42 2.98e-02 GO:0005097 Rab GTPase activator activity