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Motif ID: SMAD1..7,9.p2

Z-value: 1.582

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr21_+_46020496	6.289	NM_198689	KRTAP10-7	keratin associated protein 10-7
chr12_+_53443834	4.644	NM_170754	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr13_+_32605436	3.558	NM_023037	FRY	furry homolog (Drosophila)
chr12_-_47473424	3.443	NM_001143668 NM_181847	AMIGO2	adhesion molecule with Ig-like domain 2
chrX_-_62570968	3.202	NM_001012968	SPIN4	spindlin family, member 4
chr21_-_46012383	3.140	NM_198688	KRTAP10-6	keratin associated protein 10-6
chr7_+_1097140	3.052	NM_138445	GPR146	G protein-coupled receptor 146
chr20_+_58515408	2.877	NM_001190827 NM_022106	C20orf177	chromosome 20 open reading frame 177
chr20_+_30598244	2.847	NM_080625	C20orf160	chromosome 20 open reading frame 160
chr8_-_8239188	2.828	NM_001080826	SGK223	homolog of rat pragma of Rnd2
chr22_+_31518923	2.622	NM_001002837	INPP5J	inositol polyphosphate-5-phosphatase J
chr9_-_100459556	2.616		XPA	xeroderma pigmentosum, complementation group A
chrX_+_101967290	2.570		GPRASP2	G protein-coupled receptor associated sorting protein 2
chr4_-_16900028	2.568		LDB2	LIM domain binding 2
chr21_+_45993605	2.489	NM_198687	KRTAP10-4	keratin associated protein 10-4
chr9_-_100459623	2.488	NM_000380	XPA	xeroderma pigmentosum, complementation group A
chr3_-_64211111	2.372	NM_198859	PRICKLE2	prickle homolog 2 (Drosophila)
chr20_+_42543417	2.342	NM_001098797	TOX2	TOX high mobility group box family member 2
chr11_+_66824308	2.298		RHOD	ras homolog gene family, member D
chr2_-_188312872	2.293	NM_005795	CALCRL	calcitonin receptor-like
chr10_+_8096772	2.226		GATA3	GATA binding protein 3
chr4_-_16900348	2.193	NM_001130834 NM_001290	LDB2	LIM domain binding 2
chr20_-_45985411	2.182	NM_012408 NM_183047 NM_183048	ZMYND8	zinc finger, MYND-type containing 8
chr16_-_88772807	2.166	NM_178841	RNF166	ring finger protein 166
chr10_+_8096633	2.112	NM_001002295 NM_002051	GATA3	GATA binding protein 3
chr11_-_33913835	2.104	NM_005574	LMO2	LIM domain only 2 (rhombotin-like 1)
chr20_+_1246959	2.098	NM_014723	SNPH	syntaphilin
chr20_-_45976626	2.085		ZMYND8	zinc finger, MYND-type containing 8
chr16_-_88772732	2.067	NM_001171815	RNF166	ring finger protein 166
chr17_+_39382878	2.037	NM_031961	KRTAP9-2	keratin associated protein 9-2
chr12_+_53440809	1.951	NM_198316	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr11_-_33891485	1.938	NM_001142315	LMO2	LIM domain only 2 (rhombotin-like 1)
chr19_+_39897457	1.889	NM_003407	ZFP36	zinc finger protein 36, C3H type, homolog (mouse)
chr9_-_130617009	1.865	NM_000118 NM_001114753	ENG	endoglin
chr13_+_58205943	1.780		PCDH17	protocadherin 17
chr1_+_15272414	1.773	NM_001017999	KAZN	kazrin, periplakin interacting protein
chrX_+_102000906	1.767	NM_001142529 NM_001142530	BHLHB9	basic helix-loop-helix domain containing, class B, 9
chr1_+_65720091	1.733		LOC645195 DNAJC6	uncharacterized LOC645195 DnaJ (Hsp40) homolog, subfamily C, member 6
chrX_-_62975005	1.719	NM_001173480 NM_015185	ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr20_-_39317875	1.700	NM_005461	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr2_-_152684963	1.688	NM_001037174 NM_012097 NM_177985	ARL5A	ADP-ribosylation factor-like 5A
chr10_+_8097350	1.677		GATA3	GATA binding protein 3
chr17_-_5138049	1.649	NM_207103	SCIMP	SLP adaptor and CSK interacting membrane protein
chr1_+_22351984	1.648		LINC00339	long intergenic non-protein coding RNA 339
chr13_+_58205788	1.613	NM_001040429	PCDH17	protocadherin 17
chr20_-_35488275	1.613	NM_199181	KIAA0889	KIAA0889
chr3_+_20081853	1.595		KAT2B	K(lysine) acetyltransferase 2B
chr2_-_152684689	1.591		ARL5A	ADP-ribosylation factor-like 5A
chr19_-_2038937	1.563		MKNK2	MAP kinase interacting serine/threonine kinase 2
chr3_+_39851028	1.554	NM_015460	MYRIP	myosin VIIA and Rab interacting protein
chr11_+_74459900	1.552	NM_001098638	RNF169	ring finger protein 169
chr11_-_33891361	1.538	NM_001142316	LMO2	LIM domain only 2 (rhombotin-like 1)
chr19_-_11308184	1.504	NM_001136191	KANK2	KN motif and ankyrin repeat domains 2
chr20_+_34700257	1.489	NM_177996	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr1_+_228645807	1.476	NM_175055	HIST3H2BB	histone cluster 3, H2bb
chr12_-_58209840	1.475	NM_006576	AVIL	advillin
chr1_+_45274153	1.465	NM_001136537	BTBD19	BTB (POZ) domain containing 19
chr4_+_55523906	1.453	NM_000222 NM_001093772	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr19_+_45971249	1.443	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr10_-_52383611	1.424	NM_147156	SGMS1	sphingomyelin synthase 1
chr11_-_33890931	1.401		LMO2	LIM domain only 2 (rhombotin-like 1)
chr9_-_124984018	1.386	NM_001242335	LHX6	LIM homeobox 6
chr3_+_50304989	1.372	NM_001005914 NM_004636	SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr11_-_33891258	1.368		LMO2	LIM domain only 2 (rhombotin-like 1)
chr14_+_24867926	1.332	NM_025081	NYNRIN	NYN domain and retroviral integrase containing
chr19_+_35773409	1.294	NM_021175	HAMP	hepcidin antimicrobial peptide
chr17_-_62914902	1.258	NM_199340	LRRC37A3	leucine rich repeat containing 37, member A3
chr9_-_130616957	1.250		ENG	endoglin
chr7_+_22766765	1.249	NM_000600	IL6	interleukin 6 (interferon, beta 2)
chrX_+_101967103	1.239	NM_001004051 NM_001184874 NM_001184875 NM_001184876 NM_138437	GPRASP2	G protein-coupled receptor associated sorting protein 2
chr1_-_45672225	1.239	NM_020883	ZSWIM5	zinc finger, SWIM-type containing 5
chr15_+_63796793	1.227	NM_006537	USP3	ubiquitin specific peptidase 3
chr9_+_79056581	1.226	NM_001097634	GCNT1	glucosaminyl (N-acetyl) transferase 1, core 2
chrX_-_62974942	1.224		ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr20_-_35402142	1.219	NM_001145316 NM_024918 NM_001145315 NM_001145317 NM_001145318	DSN1	DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr1_-_36022938	1.215		KIAA0319L	KIAA0319-like
chr11_-_66445318	1.210		RBM4B	RNA binding motif protein 4B
chr11_-_66445218	1.209	NM_031492	RBM4B	RNA binding motif protein 4B
chr7_-_99766238	1.197	NM_024637	GAL3ST4	galactose-3-O-sulfotransferase 4
chr15_+_57210852	1.196		TCF12	transcription factor 12
chr10_+_135480367	1.196	NM_033178 NM_012147 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr17_-_47841517	1.186	NM_030802	FAM117A	family with sequence similarity 117, member A
chr20_-_43936919	1.172	NM_003833 NM_030590 NM_030592	MATN4	matrilin 4
chr9_-_130616760	1.168		ENG	endoglin
chr11_+_66824285	1.166	NM_014578	RHOD	ras homolog gene family, member D
chr15_+_57210889	1.166		TCF12	transcription factor 12
chr6_+_43027628	1.149	NM_201523	KLC4	kinesin light chain 4
chr4_+_191001978	1.147	NM_001177376	DUX4L4	double homeobox 4 like 4
chr4_+_191008565	1.135	NM_012147 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX2 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 2 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr4_+_190995385	1.125	NM_012147 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX2 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 2 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr4_+_190998678	1.123	NM_012147 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX2 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 2 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr4_+_190988866	1.122	NM_012147	DUX2	double homeobox 2
chr10_+_135493659	1.121	NM_012147	DUX2	double homeobox 2
chr10_+_135490278	1.111	NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr3_+_20081523	1.109	NM_003884	KAT2B	K(lysine) acetyltransferase 2B
chr9_+_90112754	1.107	NM_004938	DAPK1	death-associated protein kinase 1
chr4_+_191011859	1.106	NM_033178 NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr4_+_191005266	1.106	NM_033178 NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr9_+_140119643	1.094	NM_199001	C9orf169	chromosome 9 open reading frame 169
chr11_-_118135197	1.090	NM_005797 NM_144765	MPZL2	myelin protein zero-like 2
chr8_-_27941387	1.084	NM_001010906	C8orf80	chromosome 8 open reading frame 80
chr17_-_62915580	1.077		LRRC37A3	leucine rich repeat containing 37, member A3
chr2_-_86094792	1.074	NM_001042437	ST3GAL5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr8_-_143823823	1.072	NM_020427	SLURP1	secreted LY6/PLAUR domain containing 1
chrX_+_101975641	1.066	NM_001142524 NM_001142525 NM_001142526 NM_001142527 NM_001142528 NM_030639	BHLHB9	basic helix-loop-helix domain containing, class B, 9
chr11_-_27741192	1.065	NM_001143807	BDNF	brain-derived neurotrophic factor
chr10_-_97200895	1.062	NM_001034954 NM_001034955 NM_001034956 NM_001034957 NM_006434	SORBS1	sorbin and SH3 domain containing 1
chr11_-_62472901	1.047
chr20_-_62610990	1.047	NM_080621	SAMD10	sterile alpha motif domain containing 10
chr5_+_61714710	1.045	NM_001134779	IPO11	importin 11
chr11_-_118134956	1.032		MPZL2	myelin protein zero-like 2
chr6_+_43027368	1.028	NM_138343 NM_201521	KLC4	kinesin light chain 4
chr9_-_35111534	1.026		FAM214B	family with sequence similarity 214, member B
chr11_-_118134986	1.020		MPZL2	myelin protein zero-like 2
chr7_+_1581072	1.017		MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr5_+_176560056	1.006	NM_172349	NSD1	nuclear receptor binding SET domain protein 1
chr19_-_11308457	1.003		KANK2	KN motif and ankyrin repeat domains 2
chr6_-_111927059	1.000		TRAF3IP2	TRAF3 interacting protein 2
chr1_+_156863522	0.992	NM_001080471	PEAR1	platelet endothelial aggregation receptor 1
chr2_-_110874142	0.987	NM_005434	MALL	mal, T-cell differentiation protein-like
chrX_-_62974987	0.983		ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr20_-_36152952	0.983	NM_001167823	BLCAP	bladder cancer associated protein
chr17_-_47841468	0.973		FAM117A	family with sequence similarity 117, member A
chr10_-_116392099	0.965		ABLIM1	actin binding LIM protein 1
chr6_-_84419108	0.963	NM_001242793 NM_001242794 NM_014841	SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)
chr3_+_32148000	0.958	NM_015141	GPD1L	glycerol-3-phosphate dehydrogenase 1-like
chr19_-_41933255	0.953
chr11_+_64107687	0.947	NM_032251	CCDC88B	coiled-coil domain containing 88B
chr5_-_90679115	0.942	NM_020801	ARRDC3	arrestin domain containing 3
chr1_-_59012379	0.941	NM_145243	OMA1	OMA1 zinc metallopeptidase homolog (S. cerevisiae)
chr1_+_212459169	0.940		PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha
chr12_+_52695648	0.930	NM_002284	KRT86	keratin 86
chr9_+_130374466	0.930	NM_001032221 NM_003165	STXBP1	syntaxin binding protein 1
chr15_+_57210823	0.922	NM_003205 NM_207036 NM_207037 NM_207038	TCF12	transcription factor 12
chr7_-_99766191	0.921		GAL3ST4	galactose-3-O-sulfotransferase 4
chr3_+_44626453	0.920	NM_173658	ZNF660	zinc finger protein 660
chr6_-_84419018	0.919		SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)
chr3_+_51976274	0.917	NM_001003931 NM_005485	PARP3	poly (ADP-ribose) polymerase family, member 3
chr4_+_30721865	0.913	NM_032456 NM_001173523 NM_002589 NM_032457	PCDH7	protocadherin 7
chr1_+_212459262	0.910		PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha
chr3_+_32148136	0.906		GPD1L	glycerol-3-phosphate dehydrogenase 1-like
chr14_+_45605143	0.891		FANCM	Fanconi anemia, complementation group M
chr6_+_18387580	0.890	NM_182757	RNF144B	ring finger protein 144B
chr15_+_66995414	0.882		SMAD6	SMAD family member 6
chr9_-_130616592	0.882		ENG	endoglin
chr4_+_159131400	0.877	NM_018342	TMEM144	transmembrane protein 144
chr12_-_104443698	0.874		GLT8D2	glycosyltransferase 8 domain containing 2
chr13_+_33160537	0.867	NM_015032	PDS5B	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr22_+_29702950	0.866	NM_006478 NM_152236 NM_152237	GAS2L1	growth arrest-specific 2 like 1
chr1_-_36023005	0.865	NM_024874	KIAA0319L	KIAA0319-like
chr2_-_21022812	0.865	NM_021925	C2orf43	chromosome 2 open reading frame 43
chr1_+_221052845	0.861		HLX	H2.0-like homeobox
chr17_-_39968145	0.861		LEPREL4	leprecan-like 4
chr1_+_61542928	0.860	NM_001145511	NFIA	nuclear factor I/A
chr2_+_56411123	0.848	NM_001080433	CCDC85A	coiled-coil domain containing 85A
chr10_+_135483677	0.846	NM_033178 NM_012147 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr1_+_100111430	0.841	NM_017734	PALMD	palmdelphin
chr19_-_58067724	0.838	NM_001039654	ZNF550	zinc finger protein 550
chr3_-_171177851	0.834	NM_001161560 NM_001161561 NM_001161562 NM_001161563 NM_001161564 NM_001161565 NM_001161566 NM_015028	TNIK	TRAF2 and NCK interacting kinase
chr11_-_116693907	0.834	NM_000482	APOA4	apolipoprotein A-IV
chr1_-_11714396	0.833		FBXO2	F-box protein 2
chr1_+_221052735	0.831	NM_021958	HLX	H2.0-like homeobox
chr4_+_126237566	0.830	NM_024582	FAT4	FAT tumor suppressor homolog 4 (Drosophila)
chr11_+_59522801	0.820		STX3	syntaxin 3
chr7_-_41742666	0.819	NM_002192	INHBA	inhibin, beta A
chr2_+_177134122	0.819	NM_006554	MTX2	metaxin 2
chr1_+_16091458	0.807	NM_001024216	FBLIM1	filamin binding LIM protein 1
chr1_+_61547625	0.806	NM_001134673 NM_005595	NFIA	nuclear factor I/A
chr2_+_177053306	0.802	NM_024501	HOXD1	homeobox D1
chr6_+_16129321	0.800		MYLIP	myosin regulatory light chain interacting protein
chr11_+_59522531	0.795	NM_001178040 NM_004177	STX3	syntaxin 3
chr19_+_56152281	0.793	NM_207115	ZNF580	zinc finger protein 580
chr4_+_100871625	0.792		LOC256880	uncharacterized LOC256880
chr4_-_102268333	0.791		PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr10_-_33623771	0.791	NM_001024628 NM_001024629 NM_001244972 NM_001244973 NM_003873	NRP1	neuropilin 1
chr3_+_134514044	0.779	NM_004441	EPHB1	EPH receptor B1
chr8_-_11058847	0.771	NM_173683	XKR6	XK, Kell blood group complex subunit-related family, member 6
chr1_-_179198735	0.770		ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2
chr18_+_42260774	0.769	NM_015559	SETBP1	SET binding protein 1
chr2_+_103089761	0.767	NM_001011552	SLC9A4	solute carrier family 9 (sodium/hydrogen exchanger), member 4
chr8_-_74659942	0.766	NM_001164384	STAU2	staufen, RNA binding protein, homolog 2 (Drosophila)
chr8_-_6735438	0.761	NM_005218	DEFB1	defensin, beta 1
chr14_-_88792923	0.755		KCNK10	potassium channel, subfamily K, member 10
chr19_-_36303766	0.746		PRODH2	proline dehydrogenase (oxidase) 2
chr5_-_111093030	0.746	NM_001142482 NM_001142481	C5orf13	chromosome 5 open reading frame 13
chr3_+_126243161	0.740		CHST13	carbohydrate (chondroitin 4) sulfotransferase 13
chr15_-_40633122	0.738	NM_207380	C15orf52	chromosome 15 open reading frame 52
chr6_+_17600504	0.736	NM_016255	FAM8A1	family with sequence similarity 8, member A1
chr7_+_73442468	0.736		ELN	elastin
chr20_-_35885276	0.733	NM_001184731 NM_021081	GHRH	growth hormone releasing hormone
chr19_+_49376488	0.728		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr9_+_115513050	0.727	NM_001012994	SNX30	sorting nexin family member 30
chr2_-_211035913	0.716	NM_152519	C2orf67	chromosome 2 open reading frame 67
chr6_-_32163890	0.714		NOTCH4	notch 4
chr8_+_29952921	0.713	NM_001128208 NM_015344	LEPROTL1	leptin receptor overlapping transcript-like 1
chr1_+_32538497	0.708	NM_018056	TMEM39B	transmembrane protein 39B
chr17_-_71088831	0.703		SLC39A11	solute carrier family 39 (metal ion transporter), member 11
chr17_-_71088820	0.694		SLC39A11	solute carrier family 39 (metal ion transporter), member 11
chr1_+_10093149	0.693		UBE4B	ubiquitination factor E4B
chr15_+_57210972	0.691		TCF12	transcription factor 12

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.08	2.56e-03	GO:0009987	cellular process
1.11	5.98e-03	GO:0065007	biological regulation
1.23	7.39e-03	GO:0048731	system development
1.75	1.26e-02	GO:0006140	regulation of nucleotide metabolic process
1.18	2.86e-02	GO:0023052	signaling
1.19	3.19e-02	GO:0007275	multicellular organismal development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
2.30	3.50e-03	GO:0005925	focal adhesion
2.26	3.61e-03	GO:0005924	cell-substrate adherens junction
1.09	7.43e-03	GO:0005737	cytoplasm
2.18	8.37e-03	GO:0030055	cell-substrate junction
1.76	1.30e-02	GO:0016323	basolateral plasma membrane
1.89	1.88e-02	GO:0070161	anchoring junction
1.11	3.32e-02	GO:0044444	cytoplasmic part
1.89	4.47e-02	GO:0005912	adherens junction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.12	7.87e-04	GO:0005515	protein binding
1.53	1.57e-02	GO:0060589	nucleoside-triphosphatase regulator activity
1.54	1.60e-02	GO:0030695	GTPase regulator activity
1.35	3.20e-02	GO:0030234	enzyme regulator activity