Motif ID: SMAD1..7,9.p2

Z-value: 1.582


Transcription factors associated with SMAD1..7,9.p2:

Gene SymbolEntrez IDGene Name
SMAD1 4086 SMAD family member 1
SMAD2 4087 SMAD family member 2
SMAD3 4088 SMAD family member 3
SMAD4 4089 SMAD family member 4
SMAD5 4090 SMAD family member 5
SMAD6 4091 SMAD family member 6
SMAD7 4092 SMAD family member 7
SMAD9 4093 SMAD family member 9

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
SMAD3chr15_+_67430358-0.725.9e-05Click!
SMAD6chr15_+_669954140.691.6e-04Click!
SMAD9chr13_-_374943700.682.1e-04Click!
SMAD4chr18_+_48556483-0.582.6e-03Click!
SMAD7chr18_-_464691180.527.5e-03Click!
SMAD2chr18_-_45457145-0.527.9e-03Click!
SMAD1chr4_+_146403955-0.377.2e-02Click!
SMAD5chr5_+_1354685220.116.1e-01Click!


Activity profile for motif SMAD1..7,9.p2.

activity profile for motif SMAD1..7,9.p2


Sorted Z-values histogram for motif SMAD1..7,9.p2

Sorted Z-values for motif SMAD1..7,9.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SMAD1..7,9.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr21_+_46020496 6.289 NM_198689
 KRTAP10-7
keratin associated protein 10-7
chr12_+_53443834 4.644 NM_170754
 TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr13_+_32605436 3.558 NM_023037
 FRY
furry homolog (Drosophila)
chr12_-_47473424 3.443 NM_001143668
NM_181847
 AMIGO2

adhesion molecule with Ig-like domain 2

chrX_-_62570968 3.202 NM_001012968
 SPIN4
spindlin family, member 4
chr21_-_46012383 3.140 NM_198688
 KRTAP10-6
keratin associated protein 10-6
chr7_+_1097140 3.052 NM_138445
 GPR146
G protein-coupled receptor 146
chr20_+_58515408 2.877 NM_001190827
NM_022106
 C20orf177

chromosome 20 open reading frame 177

chr20_+_30598244 2.847 NM_080625
 C20orf160
chromosome 20 open reading frame 160
chr8_-_8239188 2.828 NM_001080826
 SGK223
homolog of rat pragma of Rnd2
chr22_+_31518923 2.622 NM_001002837
 INPP5J
inositol polyphosphate-5-phosphatase J
chr9_-_100459556 2.616 XPA
xeroderma pigmentosum, complementation group A
chrX_+_101967290 2.570 GPRASP2
G protein-coupled receptor associated sorting protein 2
chr4_-_16900028 2.568 LDB2
LIM domain binding 2
chr21_+_45993605 2.489 NM_198687
 KRTAP10-4
keratin associated protein 10-4
chr9_-_100459623 2.488 NM_000380
 XPA
xeroderma pigmentosum, complementation group A
chr3_-_64211111 2.372 NM_198859
 PRICKLE2
prickle homolog 2 (Drosophila)
chr20_+_42543417 2.342 NM_001098797
 TOX2
TOX high mobility group box family member 2
chr11_+_66824308 2.298 RHOD
ras homolog gene family, member D
chr2_-_188312872 2.293 NM_005795
 CALCRL
calcitonin receptor-like

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.75 1.26e-02 GO:0006140 regulation of nucleotide metabolic process
1.23 7.39e-03 GO:0048731 system development
1.19 3.19e-02 GO:0007275 multicellular organismal development
1.18 2.86e-02 GO:0023052 signaling
1.11 5.98e-03 GO:0065007 biological regulation
1.08 2.56e-03 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.30 3.50e-03 GO:0005925 focal adhesion
2.26 3.61e-03 GO:0005924 cell-substrate adherens junction
2.18 8.37e-03 GO:0030055 cell-substrate junction
1.89 1.88e-02 GO:0070161 anchoring junction
1.89 4.47e-02 GO:0005912 adherens junction
1.76 1.30e-02 GO:0016323 basolateral plasma membrane
1.11 3.32e-02 GO:0044444 cytoplasmic part
1.09 7.43e-03 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.54 1.60e-02 GO:0030695 GTPase regulator activity
1.53 1.57e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.35 3.20e-02 GO:0030234 enzyme regulator activity
1.12 7.87e-04 GO:0005515 protein binding