Motif ID: SNAI1..3.p2

Z-value: 1.260


Transcription factors associated with SNAI1..3.p2:

Gene SymbolEntrez IDGene Name
SNAI1 6615 snail homolog 1 (Drosophila)
SNAI2 6591 snail homolog 2 (Drosophila)
SNAI3 333929 snail homolog 3 (Drosophila)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
SNAI1chr20_+_48599511-0.262.1e-01Click!
SNAI2chr8_-_498338230.174.3e-01Click!
SNAI3chr16_-_887527880.019.7e-01Click!


Activity profile for motif SNAI1..3.p2.

activity profile for motif SNAI1..3.p2


Sorted Z-values histogram for motif SNAI1..3.p2

Sorted Z-values for motif SNAI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SNAI1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_39382878 9.392 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr4_-_149363498 4.454 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr5_+_68788387 4.365 NM_001205254
OCLN
occludin
chr4_+_55523906 4.178 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr1_+_35258598 4.164 NM_002060
GJA4
gap junction protein, alpha 4, 37kDa
chr10_+_8097350 4.037 GATA3
GATA binding protein 3
chr7_+_150690838 3.914 NM_001160109
NM_001160110
NM_001160111
NOS3


nitric oxide synthase 3 (endothelial cell)


chr8_+_120220554 3.825 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr8_+_144816287 3.762 LOC100128338
uncharacterized LOC100128338
chr8_-_93029864 3.198 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_+_41540320 3.114 LIMCH1
LIM and calponin homology domains 1
chr11_-_68518910 2.739 MTL5
metallothionein-like 5, testis-specific (tesmin)
chr11_-_33913835 2.560 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr7_+_17338182 2.501 NM_001621
AHR
aryl hydrocarbon receptor
chr19_-_12886263 2.467 HOOK2
hook homolog 2 (Drosophila)
chr20_+_42574535 2.376 NM_001098798
TOX2
TOX high mobility group box family member 2
chr7_+_12727204 2.374 ARL4A
ADP-ribosylation factor-like 4A
chr3_+_32280154 2.329 NM_178868
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr7_+_12726910 2.249 NM_001195396
NM_005738
ARL4A

ADP-ribosylation factor-like 4A

chr10_+_8096772 2.247 GATA3
GATA binding protein 3
chr8_-_81083660 2.239 NM_001025253
NM_005079
TPD52

tumor protein D52

chr10_+_94608224 2.206 NM_019053
EXOC6
exocyst complex component 6
chr3_+_32280211 2.200 CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr19_-_17356022 2.170 NM_005234
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr9_-_126030792 2.143 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr2_-_165477818 2.135 GRB14
growth factor receptor-bound protein 14
chr7_+_150688143 2.128 NM_000603
NOS3
nitric oxide synthase 3 (endothelial cell)
chr1_+_231114839 2.094


chr3_+_39851028 2.079 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr6_+_34857021 2.066 NM_015245
ANKS1A
ankyrin repeat and sterile alpha motif domain containing 1A
chr11_-_33890931 2.060 LMO2
LIM domain only 2 (rhombotin-like 1)
chr20_+_34700257 2.031 NM_177996
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr2_-_165477986 2.031 GRB14
growth factor receptor-bound protein 14
chr19_+_38755238 2.024 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr1_+_78511588 2.014 NM_017655
GIPC2
GIPC PDZ domain containing family, member 2
chr19_+_38755422 2.007 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr11_+_7618416 1.895 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr13_+_31480311 1.886 NM_032849
C13orf33
chromosome 13 open reading frame 33
chr1_-_231114580 1.879 TTC13
tetratricopeptide repeat domain 13
chr19_+_38755097 1.879 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr9_-_126030854 1.861 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr8_-_127570465 1.822 FAM84B
family with sequence similarity 84, member B
chr11_+_64879294 1.815 NM_003273
TM7SF2
transmembrane 7 superfamily member 2
chr11_+_68079999 1.802 NM_002335
LRP5
low density lipoprotein receptor-related protein 5
chr11_+_59522905 1.787 STX3
syntaxin 3
chr1_-_231114617 1.779 NM_001122835
NM_024525
TTC13

tetratricopeptide repeat domain 13

chr7_+_94023872 1.777 NM_000089
COL1A2
collagen, type I, alpha 2
chr1_-_231114596 1.756 TTC13
tetratricopeptide repeat domain 13
chr15_-_69113213 1.742 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr15_-_69113089 1.731 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr19_-_14316980 1.694 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr17_+_73521744 1.690 NM_001015002
NM_001031803
NM_004524
LLGL2


lethal giant larvae homolog 2 (Drosophila)


chr5_+_68788118 1.688 NM_002538
OCLN
occludin
chr7_+_30951414 1.681 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr19_+_39155209 1.673


chr6_+_16129321 1.662 MYLIP
myosin regulatory light chain interacting protein
chr5_+_139028483 1.634 CXXC5
CXXC finger protein 5
chr21_+_18885296 1.624 CXADR
coxsackie virus and adenovirus receptor
chr1_-_209979388 1.619 NM_001206696
NM_006147
IRF6

interferon regulatory factor 6

chr11_-_119234628 1.607 USP2
ubiquitin specific peptidase 2
chr14_-_23821423 1.589 NM_020372
SLC22A17
solute carrier family 22, member 17
chr8_+_95835586 1.583 INTS8
integrator complex subunit 8
chr15_+_41221530 1.570 NM_019074
DLL4
delta-like 4 (Drosophila)
chr19_-_12886421 1.555 NM_001100176
NM_013312
HOOK2

hook homolog 2 (Drosophila)

chr2_-_166650770 1.552 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr13_+_48877950 1.548 RB1
retinoblastoma 1
chr9_-_140196702 1.542 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr3_-_15900928 1.540 NM_015199
ANKRD28
ankyrin repeat domain 28
chr5_+_68710938 1.524 NM_001038603
NM_001244734
MARVELD2

MARVEL domain containing 2

chr17_+_38119225 1.515 NM_178171
GSDMA
gasdermin A
chr19_+_39899749 1.515


chr11_+_59522801 1.508 STX3
syntaxin 3
chr3_+_32148136 1.507 GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr1_-_59042827 1.479 TACSTD2
tumor-associated calcium signal transducer 2
chr1_+_212459262 1.472 PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr15_-_71055745 1.465 NM_018003
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr8_+_37654833 1.459 GPR124
G protein-coupled receptor 124
chr6_-_84419108 1.456 NM_001242793
NM_001242794
NM_014841
SNAP91


synaptosomal-associated protein, 91kDa homolog (mouse)


chr9_-_75568232 1.452 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr9_-_75567915 1.440 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr5_-_88199868 1.440 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr18_+_77659446 1.440


chr3_-_128207366 1.436 NM_001145661
GATA2
GATA binding protein 2
chr12_+_53443834 1.424 NM_170754
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr7_+_12726413 1.414 NM_001037164
NM_212460
ARL4A

ADP-ribosylation factor-like 4A

chr14_-_105635114 1.413 NM_002226
NM_145159
JAG2

jagged 2

chr9_-_86432546 1.397 NM_001135953
NM_025211
GKAP1

G kinase anchoring protein 1

chr11_+_63448868 1.391 NM_006054
NM_201428
NM_201429
NM_201430
RTN3



reticulon 3



chr11_-_17410205 1.372 NM_000525
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr16_+_81812899 1.371 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr17_-_7165788 1.363 CLDN7
claudin 7
chr15_-_52587851 1.356 NM_018728
MYO5C
myosin VC
chr20_-_33735060 1.352 NM_001145025
NM_018217
EDEM2

ER degradation enhancer, mannosidase alpha-like 2

chr9_+_90112754 1.348 NM_004938
DAPK1
death-associated protein kinase 1
chr12_+_82752275 1.323 NM_032230
C12orf26
chromosome 12 open reading frame 26
chr20_-_33734894 1.320 EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr8_+_143808593 1.298 NM_016647
C8orf55
chromosome 8 open reading frame 55
chr1_+_65991357 1.295 NM_001198687
NM_001198688
NM_001198689
LEPR


leptin receptor


chr1_+_231114794 1.290 NM_022786
ARV1
ARV1 homolog (S. cerevisiae)
chrX_-_70473979 1.289 NM_201599
ZMYM3
zinc finger, MYM-type 3
chr6_-_84418705 1.284 NM_001242792
SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr22_-_37882214 1.278 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr2_-_157189040 1.274 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr9_+_131314669 1.263 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr14_+_75745480 1.257 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chrX_-_70473941 1.248 ZMYM3
zinc finger, MYM-type 3
chr1_+_1981902 1.216 NM_002744
PRKCZ
protein kinase C, zeta
chr7_-_132261268 1.214 NM_001105543
NM_020911
PLXNA4

plexin A4

chr2_+_173600595 1.207 RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr7_+_16793320 1.195 NM_014399
TSPAN13
tetraspanin 13
chr6_+_18387580 1.184 NM_182757
RNF144B
ring finger protein 144B
chr5_+_148961035 1.177 NM_001001669
ARHGEF37
Rho guanine nucleotide exchange factor (GEF) 37
chr17_-_79196702 1.175 NM_001009811
NM_014984
AZI1

5-azacytidine induced 1

chr10_+_99258615 1.164 NM_024954
UBTD1
ubiquitin domain containing 1
chr3_-_49459870 1.164 AMT
aminomethyltransferase
chr11_+_64107687 1.157 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr8_-_9008138 1.149 NM_024607
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr1_+_16083132 1.145 FBLIM1
filamin binding LIM protein 1
chr8_+_356933 1.144 FBXO25
F-box protein 25
chr22_+_19744225 1.115 NM_005992
NM_080646
NM_080647
TBX1


T-box 1


chr12_+_48357358 1.114 TMEM106C
transmembrane protein 106C
chr5_+_139027907 1.108 CXXC5
CXXC finger protein 5
chr1_-_45672225 1.104 NM_020883
ZSWIM5
zinc finger, SWIM-type containing 5
chr1_+_109102970 1.104 NM_001010883
FAM102B
family with sequence similarity 102, member B
chr8_+_356807 1.102 NM_012173
NM_183420
NM_183421
FBXO25


F-box protein 25


chr12_+_93963597 1.101 NM_003877
SOCS2
suppressor of cytokine signaling 2
chr13_+_48878025 1.100 RB1
retinoblastoma 1
chr16_+_30406711 1.097 NM_152652
ZNF48
zinc finger protein 48
chr10_-_50747080 1.097 NM_000124
ERCC6
PGBD3
excision repair cross-complementing rodent repair deficiency, complementation group 6
piggyBac transposable element derived 3
chr20_+_1246959 1.090 NM_014723
SNPH
syntaphilin
chrX_+_152770083 1.089 BGN
biglycan
chr10_-_72083678 1.082 LRRC20
leucine rich repeat containing 20
chr4_+_126237566 1.082 NM_024582
FAT4
FAT tumor suppressor homolog 4 (Drosophila)
chr3_-_197282805 1.079 NM_004051
NM_203314
BDH1

3-hydroxybutyrate dehydrogenase, type 1

chr7_+_150211944 1.076 NM_153236
GIMAP7
GTPase, IMAP family member 7
chr7_-_149470294 1.070 NM_207336
ZNF467
zinc finger protein 467
chr6_+_30881981 1.067 NM_001167733
NM_020442
NM_001167734
VARS2


valyl-tRNA synthetase 2, mitochondrial (putative)


chr7_+_106685007 1.065 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr20_-_23030141 1.064 NM_000361
THBD
thrombomodulin
chr19_-_7939325 1.059 NM_001190467
FLJ22184
putative uncharacterized protein FLJ22184
chr2_+_173600634 1.057 RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr3_+_50192420 1.049 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr8_+_1712011 1.048 CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr12_+_51318743 1.042 METTL7A
methyltransferase like 7A
chr11_+_7535000 1.038 NM_003621
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr6_+_11538486 1.036 NM_001100829
TMEM170B
transmembrane protein 170B
chr12_-_80084023 1.034 PAWR
PRKC, apoptosis, WT1, regulator
chr11_-_71746966 1.032


chr13_+_78271820 1.031 NM_001242868
SLAIN1
SLAIN motif family, member 1
chr5_+_176560056 1.030 NM_172349
NSD1
nuclear receptor binding SET domain protein 1
chr15_-_69113255 1.026 NM_006305
ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr11_+_94822937 1.018 NM_015036
ENDOD1
endonuclease domain containing 1
chr19_-_2041862 1.013 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr7_-_8301767 1.011 NM_001136020
ICA1
islet cell autoantigen 1, 69kDa
chr9_+_108006990 1.004 SLC44A1
solute carrier family 44, member 1
chr4_+_134073180 1.004 PCDH10
protocadherin 10
chr11_+_7535213 1.003 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr3_-_128294928 1.003 NM_007354
C3orf27
chromosome 3 open reading frame 27
chr4_+_41700736 0.998 LIMCH1
LIM and calponin homology domains 1
chr15_+_74218962 0.988 LOXL1
lysyl oxidase-like 1
chr19_+_7660698 0.988 NM_001080429
NM_020902
CAMSAP3

calmodulin regulated spectrin-associated protein family, member 3

chr2_+_177053306 0.981 NM_024501
HOXD1
homeobox D1
chr6_-_42016383 0.980 CCND3
cyclin D3
chr15_+_66585632 0.975 NM_133375
DIS3L
DIS3 mitotic control homolog (S. cerevisiae)-like
chr6_+_2765561 0.974 WRNIP1
Werner helicase interacting protein 1
chr8_+_95835517 0.973 NM_017864
INTS8
integrator complex subunit 8
chr1_+_65720091 0.969 LOC645195
DNAJC6
uncharacterized LOC645195
DnaJ (Hsp40) homolog, subfamily C, member 6
chr3_-_66024508 0.967 NM_001033057
NM_004742
NM_015520
MAGI1


membrane associated guanylate kinase, WW and PDZ domain containing 1


chr3_-_32023237 0.966 NM_001174060
NM_017784
OSBPL10

oxysterol binding protein-like 10

chr13_-_77460432 0.959 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr4_-_144621827 0.955 NM_001168235
FREM3
FRAS1 related extracellular matrix 3
chr14_-_54423448 0.954 NM_001202
NM_130850
BMP4

bone morphogenetic protein 4

chr16_+_68771192 0.953 NM_004360
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr8_+_22436641 0.948 PDLIM2
PDZ and LIM domain 2 (mystique)
chr5_-_133747592 0.947 NM_080656
CDKN2AIPNL
CDKN2A interacting protein N-terminal like
chr1_-_154928595 0.943 PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr15_-_44487468 0.938 FRMD5
FERM domain containing 5
chr17_-_8534008 0.937 NM_005964
MYH10
myosin, heavy chain 10, non-muscle
chr16_+_14164879 0.935 NM_014048
MKL2
MKL/myocardin-like 2
chr15_-_102029872 0.932 PCSK6
proprotein convertase subtilisin/kexin type 6
chr11_-_134123138 0.931 NM_001037304
NM_001037305
NM_014174
NM_199297
NM_199298
THYN1




thymocyte nuclear protein 1




chr4_-_42658883 0.923 NM_001105529
NM_006095
ATP8A1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr19_+_14017038 0.916 CC2D1A
coiled-coil and C2 domain containing 1A
chr6_+_30852756 0.916 NM_001202523
DDR1
discoidin domain receptor tyrosine kinase 1
chr17_-_57184116 0.916 TRIM37
tripartite motif containing 37
chr12_-_10826890 0.916 NM_018423
STYK1
serine/threonine/tyrosine kinase 1
chr8_-_16859540 0.913 NM_019851
FGF20
fibroblast growth factor 20
chr16_-_28550324 0.911 NM_001042483
NM_012385
NUPR1

nuclear protein, transcriptional regulator, 1

chr6_-_13408368 0.908 NM_001242630
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr12_+_53342654 0.907 NM_199187
KRT18
keratin 18
chr17_-_16395084 0.907 FAM211A
family with sequence similarity 211, member A
chr6_+_158957652 0.900 TMEM181
transmembrane protein 181
chr15_-_44487237 0.900 NM_032892
FRMD5
FERM domain containing 5
chr1_-_27339448 0.897 FAM46B
family with sequence similarity 46, member B
chr4_-_102268626 0.893 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr15_+_77287688 0.890 PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr12_+_7055753 0.888 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr17_+_72744775 0.888 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr10_-_50747038 0.887 ERCC6
excision repair cross-complementing rodent repair deficiency, complementation group 6
chr6_-_130031278 0.881 NM_033515
ARHGAP18
Rho GTPase activating protein 18

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.07 2.60e-07 GO:0009987 cellular process
1.12 2.62e-02 GO:0023052 signaling
1.12 2.75e-02 GO:0007165 signal transduction

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 2.41e-08 GO:0005737 cytoplasm
1.11 9.55e-06 GO:0044444 cytoplasmic part
1.60 5.98e-05 GO:0016323 basolateral plasma membrane
1.18 9.28e-05 GO:0044459 plasma membrane part
1.60 4.59e-03 GO:0070161 anchoring junction
1.04 5.66e-03 GO:0005622 intracellular
1.18 8.69e-03 GO:0012505 endomembrane system
1.04 9.74e-03 GO:0044424 intracellular part
1.29 1.89e-02 GO:0030054 cell junction
1.14 2.62e-02 GO:0031090 organelle membrane
1.57 2.82e-02 GO:0005912 adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.09 1.68e-05 GO:0005515 protein binding
1.05 1.74e-04 GO:0005488 binding