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Motif ID: SOX{8,9,10}.p2

Z-value: 1.208

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_-_11232900	3.907		NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr21_+_26934440	3.207		MIR155HG	MIR155 host gene (non-protein coding)
chr5_-_131826426	3.052	NM_002198	IRF1	interferon regulatory factor 1
chr19_+_45504686	2.796	NM_006509	RELB	v-rel reticuloendotheliosis viral oncogene homolog B
chr6_-_11232883	2.570		NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr10_+_6244839	2.472	NM_004566	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr1_-_205290756	2.463	NM_030952	NUAK2	NUAK family, SNF1-like kinase, 2
chr6_-_11232901	2.384	NM_006403 NM_182966	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr2_+_228678556	2.211	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr19_-_49658645	2.171	NM_002152	HRC	histidine rich calcium binding protein
chr15_+_52311438	2.160		MAPK6	mitogen-activated protein kinase 6
chr3_+_186648515	2.132		ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr6_-_10415438	2.112	NM_003220	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr2_-_208031570	2.052		KLF7	Kruppel-like factor 7 (ubiquitous)
chr21_+_43710190	2.018		ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr5_-_16936290	2.012		MYO10	myosin X
chr14_-_51135021	1.932	NM_021818	SAV1	salvador homolog 1 (Drosophila)
chr16_-_75590107	1.915	NM_001077416 NM_001077418 NM_001077419	TMEM231	transmembrane protein 231
chr15_+_52311432	1.908		MAPK6	mitogen-activated protein kinase 6
chr22_-_19512859	1.886	NM_001130861 NM_003277	CLDN5	claudin 5
chr6_+_14117486	1.832	NM_001251901	CD83	CD83 molecule
chr15_+_52311408	1.796	NM_002748	MAPK6	mitogen-activated protein kinase 6
chr4_+_156680125	1.745	NM_000857	GUCY1B3	guanylate cyclase 1, soluble, beta 3
chr7_+_77167351	1.725	NM_001131008 NM_001131009	PTPN12	protein tyrosine phosphatase, non-receptor type 12
chr2_+_102979096	1.651	NM_003855	IL18R1	interleukin 18 receptor 1
chr4_+_78079302	1.632		CCNG2	cyclin G2
chr7_+_73703704	1.574	NM_003388 NM_032421	CLIP2	CAP-GLY domain containing linker protein 2
chr11_+_128563955	1.537		FLI1	Friend leukemia virus integration 1
chr3_+_9439533	1.508		SETD5	SET domain containing 5
chr9_-_123689172	1.485	NM_005658	TRAF1	TNF receptor-associated factor 1
chr20_-_17662704	1.484		RRBP1	ribosome binding protein 1 homolog 180kDa (dog)
chr9_-_123476578	1.474	NM_001080497	MEGF9	multiple EGF-like-domains 9
chr1_-_182360181	1.457		GLUL	glutamate-ammonia ligase
chr7_+_150065968	1.447		REPIN1	replication initiator 1
chr11_-_126138789	1.429		SRPR	signal recognition particle receptor (docking protein)
chr4_-_76598558	1.410		G3BP2	GTPase activating protein (SH3 domain) binding protein 2
chr11_-_10830034	1.406		EIF4G2	eukaryotic translation initiation factor 4 gamma, 2
chr6_-_75915566	1.366	NM_004370 NM_080645	COL12A1	collagen, type XII, alpha 1
chr14_+_55168831	1.349		SAMD4A	sterile alpha motif domain containing 4A
chr1_-_235491448	1.323		ARID4B	AT rich interactive domain 4B (RBP1-like)
chr11_+_63953630	1.320		STIP1	stress-induced-phosphoprotein 1
chr18_-_48723689	1.305		MEX3C	mex-3 homolog C (C. elegans)
chr1_-_12677347	1.287	NM_004753	DHRS3	dehydrogenase/reductase (SDR family) member 3
chr9_+_91003987	1.282		SPIN1	spindlin 1
chr1_-_221915426	1.269		DUSP10	dual specificity phosphatase 10
chr14_-_51134862	1.254		SAV1	salvador homolog 1 (Drosophila)
chr14_-_51135041	1.252		SAV1	salvador homolog 1 (Drosophila)
chr16_+_50776012	1.243	NM_001042412	CYLD	cylindromatosis (turban tumor syndrome)
chr1_-_182357757	1.227		GLUL	glutamate-ammonia ligase
chr16_+_50775960	1.215	NM_001042355 NM_015247	CYLD	cylindromatosis (turban tumor syndrome)
chr19_-_10491172	1.213		TYK2	tyrosine kinase 2
chr22_+_33197678	1.191		TIMP3	TIMP metallopeptidase inhibitor 3
chr8_-_119123804	1.170	NM_000127	EXT1	exostosin 1
chr19_+_8455243	1.164		RAB11B	RAB11B, member RAS oncogene family
chr19_+_8455265	1.162		RAB11B	RAB11B, member RAS oncogene family
chr20_-_17662828	1.158	NM_001042576 NM_004587	RRBP1	ribosome binding protein 1 homolog 180kDa (dog)
chr5_+_140739589	1.155	NM_018923 NM_032096	PCDHGB2	protocadherin gamma subfamily B, 2
chr12_-_88974094	1.144	NM_000899 NM_003994	KITLG	KIT ligand
chr19_-_10491212	1.133	NM_003331	TYK2	tyrosine kinase 2
chrX_+_15518899	1.097	NM_203281	BMX	BMX non-receptor tyrosine kinase
chr12_-_6233684	1.081	NM_000552	VWF	von Willebrand factor
chr6_+_126240369	1.075	NM_001199622	NCOA7	nuclear receptor coactivator 7
chr16_-_58663727	1.058		CNOT1	CCR4-NOT transcription complex, subunit 1
chr8_+_126442557	1.058	NM_025195	TRIB1	tribbles homolog 1 (Drosophila)
chrX_+_68048792	1.041	NM_004429	EFNB1	ephrin-B1
chr2_-_37899227	1.021	NM_006449	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr2_-_37898768	1.018		CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr22_+_33197744	1.018		TIMP3	TIMP metallopeptidase inhibitor 3
chr9_-_74383301	1.004	NM_001135820 NM_013390	TMEM2	transmembrane protein 2
chr11_+_75526236	0.995		UVRAG	UV radiation resistance associated gene
chr5_+_140797243	0.995	NM_018927	PCDHGB7	protocadherin gamma subfamily B, 7
chr11_+_128563993	0.991		FLI1	Friend leukemia virus integration 1
chr6_+_160183510	0.980		ACAT2	acetyl-CoA acetyltransferase 2
chr11_+_63953666	0.970		STIP1	stress-induced-phosphoprotein 1
chr7_+_28452143	0.966	NM_182898	CREB5	cAMP responsive element binding protein 5
chr10_+_102106771	0.961	NM_005063	SCD	stearoyl-CoA desaturase (delta-9-desaturase)
chrY_-_21239250	0.957		TTTY14	testis-specific transcript, Y-linked 14 (non-protein coding)
chr3_-_9439122	0.957		LOC440944	uncharacterized LOC440944
chr7_+_100450327	0.957		SLC12A9	solute carrier family 12 (potassium/chloride transporters), member 9
chr6_+_41040713	0.952		NFYA	nuclear transcription factor Y, alpha
chr11_-_72380107	0.944	NM_001146209	PDE2A	phosphodiesterase 2A, cGMP-stimulated
chr1_+_25071906	0.944		CLIC4	chloride intracellular channel 4
chr12_+_64238511	0.941	NM_020762	SRGAP1	SLIT-ROBO Rho GTPase activating protein 1
chr22_-_50523780	0.936	NM_139202	MLC1	megalencephalic leukoencephalopathy with subcortical cysts 1
chr11_+_128564130	0.932		FLI1	Friend leukemia virus integration 1
chr22_-_50523737	0.931		MLC1	megalencephalic leukoencephalopathy with subcortical cysts 1
chr15_+_41625152	0.931		NUSAP1	nucleolar and spindle associated protein 1
chr12_-_51477138	0.930		CSRNP2	cysteine-serine-rich nuclear protein 2
chr5_-_43313492	0.918		HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr6_+_114178516	0.913	NM_002356	MARCKS	myristoylated alanine-rich protein kinase C substrate
chr22_-_50523853	0.913		MLC1	megalencephalic leukoencephalopathy with subcortical cysts 1
chr22_-_43343046	0.912	NM_007229	PACSIN2	protein kinase C and casein kinase substrate in neurons 2
chr19_-_55677919	0.910	NM_178837	C19orf51	chromosome 19 open reading frame 51
chr2_-_54198055	0.909
chr5_-_95297424	0.907		ELL2	elongation factor, RNA polymerase II, 2
chr8_+_86157693	0.905	NM_198584	CA13	carbonic anhydrase XIII
chr2_-_175869910	0.905	NM_001822 NM_001025201	CHN1	chimerin (chimaerin) 1
chr2_-_204399906	0.898	NM_203365 NM_213589	RAPH1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr14_-_92413738	0.892		FBLN5	fibulin 5
chr5_+_140797270	0.882		PCDHGB7	protocadherin gamma subfamily B, 7
chr11_+_128563973	0.879		FLI1	Friend leukemia virus integration 1
chr11_+_75526211	0.878	NM_003369	UVRAG	UV radiation resistance associated gene
chr11_-_126138698	0.872		SRPR	signal recognition particle receptor (docking protein)
chr19_-_44100127	0.865	NM_001007561	IRGQ	immunity-related GTPase family, Q
chr5_+_40680042	0.864		PTGER4	prostaglandin E receptor 4 (subtype EP4)
chr11_-_128457452	0.863	NM_001143820	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr5_+_140729723	0.861	NM_018922 NM_032095	PCDHGB1	protocadherin gamma subfamily B, 1
chr5_-_146435589	0.859	NM_181674 NM_181676	PPP2R2B	protein phosphatase 2, regulatory subunit B, beta
chr2_-_224810020	0.850		WDFY1	WD repeat and FYVE domain containing 1
chr2_+_169923531	0.847	NM_199204	DHRS9	dehydrogenase/reductase (SDR family) member 9
chr5_+_170846659	0.840	NM_003862	FGF18	fibroblast growth factor 18
chr4_-_76598563	0.833		G3BP2	GTPase activating protein (SH3 domain) binding protein 2
chr2_+_220309373	0.832		SPEG	SPEG complex locus
chr1_+_25071967	0.829		CLIC4	chloride intracellular channel 4
chr11_+_128563772	0.826	NM_001167681 NM_002017	FLI1	Friend leukemia virus integration 1
chr10_+_97803064	0.818	NM_001134375 NM_001134376 NM_019084	CCNJ	cyclin J
chr4_+_41614911	0.806	NM_001112719 NM_001112720	LIMCH1	LIM and calponin homology domains 1
chr14_+_63671101	0.803	NM_020663	RHOJ	ras homolog gene family, member J
chr9_+_116263706	0.800	NM_130795	RGS3	regulator of G-protein signaling 3
chr2_+_170590454	0.797		KLHL23	kelch-like 23 (Drosophila)
chr1_-_55352893	0.795		DHCR24	24-dehydrocholesterol reductase
chrX_+_41193409	0.794		DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
chr9_-_139658959	0.787	NM_203347	LCN15	lipocalin 15
chr11_-_57417247	0.783	NM_145008	YPEL4	yippee-like 4 (Drosophila)
chr12_+_110011616	0.781		MVK	mevalonate kinase
chr8_-_38325524	0.781		FGFR1	fibroblast growth factor receptor 1
chr11_+_63953586	0.779	NM_006819	STIP1	stress-induced-phosphoprotein 1
chr11_+_67007488	0.776		KDM2A	lysine (K)-specific demethylase 2A
chr3_+_196466806	0.776		PAK2	p21 protein (Cdc42/Rac)-activated kinase 2
chrX_-_45060081	0.774	NM_024689 NM_176819	CXorf36	chromosome X open reading frame 36
chr22_-_50524357	0.772	NM_015166	MLC1	megalencephalic leukoencephalopathy with subcortical cysts 1
chr1_-_95392449	0.771		CNN3	calponin 3, acidic
chr16_-_84538219	0.761	NM_020947	KIAA1609	KIAA1609
chr17_-_49124128	0.754	NM_001251971	SPAG9	sperm associated antigen 9
chr8_-_6420454	0.753	NM_001118887 NM_001118888 NM_001147	ANGPT2	angiopoietin 2
chr4_+_41614933	0.750		LIMCH1	LIM and calponin homology domains 1
chr19_+_57106622	0.747	NM_021216	ZNF71	zinc finger protein 71
chr5_+_74633043	0.745		HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase
chr11_+_129991582	0.741		APLP2	amyloid beta (A4) precursor-like protein 2
chr12_+_108909049	0.736	NM_007076	FICD	FIC domain containing
chr1_-_221915458	0.735	NM_007207 NM_144729	DUSP10	dual specificity phosphatase 10
chr14_-_55369163	0.733	NM_000161 NM_001024024 NM_001024070 NM_001024071	GCH1	GTP cyclohydrolase 1
chr1_-_55352920	0.727	NM_014762	DHCR24	24-dehydrocholesterol reductase
chr1_-_235491494	0.726	NM_016374 NM_031371	ARID4B	AT rich interactive domain 4B (RBP1-like)
chr11_-_126138824	0.723	NM_001177842 NM_003139	SRPR	signal recognition particle receptor (docking protein)
chr6_-_30655078	0.722	NM_001134870	PPP1R18	protein phosphatase 1, regulatory subunit 18
chr8_-_101965096	0.715		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr16_+_67063214	0.714		CBFB	core-binding factor, beta subunit
chr22_-_43411129	0.713		PACSIN2	protein kinase C and casein kinase substrate in neurons 2
chr1_-_55352818	0.713		DHCR24	24-dehydrocholesterol reductase
chr15_+_85923739	0.709	NM_006738 NM_007200	AKAP13	A kinase (PRKA) anchor protein 13
chr1_-_221915393	0.708		DUSP10	dual specificity phosphatase 10
chr2_-_224810015	0.706		WDFY1	WD repeat and FYVE domain containing 1
chr3_-_160283071	0.705		KPNA4	karyopherin alpha 4 (importin alpha 3)
chr3_+_44690216	0.700	NM_003420	ZNF35	zinc finger protein 35
chr16_-_84651519	0.699		COTL1	coactosin-like 1 (Dictyostelium)
chr10_+_18948276	0.694	NM_178815	ARL5B	ADP-ribosylation factor-like 5B
chr3_-_160283166	0.686		KPNA4	karyopherin alpha 4 (importin alpha 3)
chr6_+_26383323	0.685	NM_001197238 NM_001197239 NM_001197240 NM_006995 NM_181531 NM_001197237	BTN2A2	butyrophilin, subfamily 2, member A2
chr6_+_83072922	0.679	NM_006670	TPBG	trophoblast glycoprotein
chr2_-_224810041	0.678	NM_020830	WDFY1	WD repeat and FYVE domain containing 1
chr1_-_55352881	0.673		DHCR24	24-dehydrocholesterol reductase
chr7_-_11871735	0.671	NM_015204	THSD7A	thrombospondin, type I, domain containing 7A
chr6_-_107435635	0.668	NM_001080450	BEND3	BEN domain containing 3
chr6_+_160182988	0.667	NM_005891	ACAT2	acetyl-CoA acetyltransferase 2
chr2_-_158182154	0.667	NM_020711	ERMN	ermin, ERM-like protein
chr2_+_159313407	0.666		PKP4	plakophilin 4
chr7_-_75368276	0.666	NM_001243198 NM_005338	HIP1	huntingtin interacting protein 1
chr9_+_92219926	0.664	NM_006705	GADD45G	growth arrest and DNA-damage-inducible, gamma
chr6_+_160183062	0.663		ACAT2	acetyl-CoA acetyltransferase 2
chr5_+_113698015	0.661	NM_021614	KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr18_+_55888799	0.659		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr3_-_71353910	0.653	NM_001244812	FOXP1	forkhead box P1
chr6_-_32163890	0.649		NOTCH4	notch 4
chr7_-_75368216	0.648		HIP1	huntingtin interacting protein 1
chr19_-_47734215	0.647	NM_014417	BBC3	BCL2 binding component 3
chr6_-_30654978	0.645		PPP1R18	protein phosphatase 1, regulatory subunit 18
chr6_+_30688085	0.643		TUBB	tubulin, beta class I
chr19_+_799281	0.642		PTBP1	polypyrimidine tract binding protein 1
chr8_-_82395401	0.638	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr14_+_59655351	0.638	NM_014992	DAAM1	dishevelled associated activator of morphogenesis 1
chr11_-_69519105	0.634	NM_005117	FGF19	fibroblast growth factor 19
chr1_-_85930610	0.628		DDAH1	dimethylarginine dimethylaminohydrolase 1
chr5_-_43313581	0.626	NM_001098272 NM_002130	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr1_-_153643433	0.623		ILF2	interleukin enhancer binding factor 2, 45kDa
chr18_+_55888838	0.621		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr14_+_103589711	0.619		TNFAIP2	tumor necrosis factor, alpha-induced protein 2
chr2_-_43453724	0.616		ZFP36L2	zinc finger protein 36, C3H type-like 2
chr4_-_101439071	0.616	NM_001159694 NM_016242	EMCN	endomucin
chr7_+_5632453	0.615		FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr14_+_103800534	0.615		EIF5	eukaryotic translation initiation factor 5
chr1_-_153643456	0.614		ILF2	interleukin enhancer binding factor 2, 45kDa
chr14_-_91884164	0.613	NM_001080414	CCDC88C	coiled-coil domain containing 88C
chr4_+_41540320	0.607		LIMCH1	LIM and calponin homology domains 1
chr16_-_22385596	0.607	NM_001802	CDR2	cerebellar degeneration-related protein 2, 62kDa
chr2_+_189839132	0.606		COL3A1	collagen, type III, alpha 1
chr14_-_73453651	0.605	NM_178441	ZFYVE1	zinc finger, FYVE domain containing 1
chr19_+_42580333	0.604		ZNF574	zinc finger protein 574
chr1_-_153643428	0.603		ILF2	interleukin enhancer binding factor 2, 45kDa
chr19_+_42580275	0.602	NM_022752	ZNF574	zinc finger protein 574

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.40	7.76e-10	GO:0007275	multicellular organismal development
1.37	1.09e-09	GO:0032502	developmental process
1.35	2.03e-06	GO:0048856	anatomical structure development
1.37	4.54e-06	GO:0048731	system development
1.52	2.63e-05	GO:0007399	nervous system development
1.22	7.98e-05	GO:0032501	multicellular organismal process
1.10	1.62e-04	GO:0009987	cellular process
1.16	1.77e-04	GO:0050789	regulation of biological process
1.15	6.80e-04	GO:0065007	biological regulation
1.16	9.07e-04	GO:0050794	regulation of cellular process
2.75	2.65e-03	GO:0007265	Ras protein signal transduction
1.85	1.12e-02	GO:0007264	small GTPase mediated signal transduction
1.71	2.09e-02	GO:0007417	central nervous system development
1.32	3.06e-02	GO:0030154	cell differentiation
1.31	4.33e-02	GO:0048869	cellular developmental process
1.23	4.38e-02	GO:0016043	cellular component organization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.22	2.02e-06	GO:0005634	nucleus
1.08	7.25e-04	GO:0005622	intracellular
1.08	1.33e-03	GO:0044424	intracellular part
3.29	3.33e-03	GO:0000786	nucleosome
1.10	2.00e-02	GO:0043227	membrane-bounded organelle
1.10	2.11e-02	GO:0043231	intracellular membrane-bounded organelle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	5.60e-05	GO:0005515	protein binding
1.09	6.06e-05	GO:0005488	binding
1.29	6.50e-03	GO:0003677	DNA binding
1.46	1.06e-02	GO:0001071	nucleic acid binding transcription factor activity
1.46	1.06e-02	GO:0003700	sequence-specific DNA binding transcription factor activity