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Motif ID: SOX2.p2

Z-value: 1.292

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_84647342	10.490	NM_001242862	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr4_-_101439071	8.184	NM_001159694 NM_016242	EMCN	endomucin
chr4_-_186732047	7.306	NM_001145672	SORBS2	sorbin and SH3 domain containing 2
chr3_-_149051258	5.639	NM_001184723 NM_138786	TM4SF18	transmembrane 4 L six family member 18
chr4_-_186732208	5.215	NM_001145671	SORBS2	sorbin and SH3 domain containing 2
chr1_+_61547388	4.864	NM_001145512	NFIA	nuclear factor I/A
chr2_-_188312872	4.616	NM_005795	CALCRL	calcitonin receptor-like
chr6_-_130031278	4.532	NM_033515	ARHGAP18	Rho GTPase activating protein 18
chr8_-_80993009	4.235	NM_001025252	TPD52	tumor protein D52
chr1_+_100111430	3.936	NM_017734	PALMD	palmdelphin
chr17_-_67138013	3.777	NM_080284	ABCA6	ATP-binding cassette, sub-family A (ABC1), member 6
chr7_-_11871735	3.537	NM_015204	THSD7A	thrombospondin, type I, domain containing 7A
chr4_+_41614933	3.495		LIMCH1	LIM and calponin homology domains 1
chr4_+_41614725	3.459		LIMCH1	LIM and calponin homology domains 1
chr4_+_41614911	3.391	NM_001112719 NM_001112720	LIMCH1	LIM and calponin homology domains 1
chrX_+_86772714	3.202	NM_019117 NM_057162	KLHL4	kelch-like 4 (Drosophila)
chr4_+_41540187	3.132		LIMCH1	LIM and calponin homology domains 1
chr5_-_88199868	3.075	NM_001131005 NM_001193347	MEF2C	myocyte enhancer factor 2C
chr1_+_61547625	2.966	NM_001134673 NM_005595	NFIA	nuclear factor I/A
chr4_+_41540320	2.804		LIMCH1	LIM and calponin homology domains 1
chr2_+_12857885	2.713		TRIB2	tribbles homolog 2 (Drosophila)
chr12_+_20724797	2.632	NM_001244683	PDE3A	phosphodiesterase 3A, cGMP-inhibited
chr1_+_84768333	2.609	NM_001134664	SAMD13	sterile alpha motif domain containing 13
chr7_+_102553343	2.588	NM_001031692 NM_005824	LRRC17	leucine rich repeat containing 17
chr2_+_12856813	2.577	NM_021643	TRIB2	tribbles homolog 2 (Drosophila)
chr5_-_111091947	2.495	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chr1_+_61869699	2.482		NFIA	nuclear factor I/A
chr2_-_111230651	2.388	NM_001205288 NM_033514	LIMS3-LOC440895 LIMS3L LIMS3	LIMS3-LOC440895 readthrough LIM and senescent cell antigen-like domains 3-like LIM and senescent cell antigen-like domains 3
chr18_+_42260774	2.368	NM_015559	SETBP1	SET binding protein 1
chr2_+_110656008	2.331	NM_001205288 NM_033514	LIMS3-LOC440895 LIMS3L LIMS3	LIMS3-LOC440895 readthrough LIM and senescent cell antigen-like domains 3-like LIM and senescent cell antigen-like domains 3
chr6_-_32163890	2.236		NOTCH4	notch 4
chr18_+_72922725	2.200	NM_005786	TSHZ1	teashirt zinc finger homeobox 1
chr2_-_157189040	2.127	NM_006186	NR4A2	nuclear receptor subfamily 4, group A, member 2
chr8_-_17579729	2.113	NM_001001931	MTUS1	microtubule associated tumor suppressor 1
chr1_+_84630575	2.030	NM_001242860 NM_001242861	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr15_-_82338348	2.020	NM_032246	MEX3B	mex-3 homolog B (C. elegans)
chr15_-_82338459	1.946		MEX3B	mex-3 homolog B (C. elegans)
chr17_+_65822242	1.933		BPTF	bromodomain PHD finger transcription factor
chr2_+_33359607	1.919	NM_000627 NM_001166264 NM_001166265 NM_001166266	LTBP1	latent transforming growth factor beta binding protein 1
chr9_-_14313509	1.910		NFIB	nuclear factor I/B
chr8_-_93029864	1.905	NM_175636	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_+_65822206	1.896		BPTF	bromodomain PHD finger transcription factor
chr9_-_14313899	1.875		NFIB	nuclear factor I/B
chr12_+_53443834	1.847	NM_170754	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr2_-_165424993	1.842		GRB14	growth factor receptor-bound protein 14
chrX_+_100333835	1.835	NM_021637	TMEM35	transmembrane protein 35
chr6_-_76203256	1.815	NM_015687	FILIP1	filamin A interacting protein 1
chr9_-_14086901	1.760		NFIB	nuclear factor I/B
chr8_-_93107442	1.745	NM_001198629 NM_001198630 NM_001198632 NM_175635	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr21_+_18885104	1.744	NM_001207063 NM_001207064 NM_001207065 NM_001207066 NM_001338	CXADR	coxsackie virus and adenovirus receptor
chr2_+_109271484	1.693		LIMS1 LIMS3	LIM and senescent cell antigen-like domains 1 LIM and senescent cell antigen-like domains 3
chr13_-_72440143	1.672		DACH1	dachshund homolog 1 (Drosophila)
chr9_-_14398981	1.662	NM_001190738	NFIB	nuclear factor I/B
chr2_-_75788027	1.639		FAM176A	family with sequence similarity 176, member A
chr1_+_84630014	1.635	NM_001242857 NM_001242858 NM_001242859	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chrX_+_80457302	1.633	NM_003022	SH3BGRL	SH3 domain binding glutamic acid-rich protein like
chr7_+_150690838	1.623	NM_001160109 NM_001160110 NM_001160111	NOS3	nitric oxide synthase 3 (endothelial cell)
chr1_-_153029987	1.604	NM_005988	SPRR2A	small proline-rich protein 2A
chr1_-_182357757	1.595		GLUL	glutamate-ammonia ligase
chr2_-_70475563	1.580	NM_022037 NM_022173	TIA1	TIA1 cytotoxic granule-associated RNA binding protein
chr17_+_39382878	1.575	NM_031961	KRTAP9-2	keratin associated protein 9-2
chr3_-_66024508	1.575	NM_001033057 NM_004742 NM_015520	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1
chrX_+_80457559	1.572		SH3BGRL	SH3 domain binding glutamic acid-rich protein like
chr3_-_168864325	1.564	NM_001105078	MECOM	MDS1 and EVI1 complex locus
chr11_-_71752099	1.544		NUMA1	nuclear mitotic apparatus protein 1
chr18_-_22932109	1.541	NM_015461	ZNF521	zinc finger protein 521
chr9_+_91003987	1.528		SPIN1	spindlin 1
chr5_-_39424930	1.524		DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr18_-_53177999	1.484	NM_001243231	TCF4	transcription factor 4
chr5_-_88119604	1.478	NM_001193348 NM_001193349	MEF2C	myocyte enhancer factor 2C
chr10_+_35464514	1.464	NM_182769 NM_182770	CREM	cAMP responsive element modulator
chr19_-_17375522	1.464	NM_031941	USHBP1	Usher syndrome 1C binding protein 1
chr2_-_136873740	1.463	NM_001008540	CXCR4	chemokine (C-X-C motif) receptor 4
chr12_+_93963597	1.460	NM_003877	SOCS2	suppressor of cytokine signaling 2
chr12_+_53442732	1.455	NM_015319	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr21_+_18885296	1.430		CXADR	coxsackie virus and adenovirus receptor
chrX_+_80457597	1.420		SH3BGRL	SH3 domain binding glutamic acid-rich protein like
chr7_+_16793320	1.407	NM_014399	TSPAN13	tetraspanin 13
chr1_+_87797371	1.400		LMO4	LIM domain only 4
chr3_+_134514044	1.391	NM_004441	EPHB1	EPH receptor B1
chr5_-_39425030	1.388		DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr5_-_111092918	1.388	NM_004772	C5orf13	chromosome 5 open reading frame 13
chr20_-_39317875	1.383	NM_005461	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr20_+_42543417	1.339	NM_001098797	TOX2	TOX high mobility group box family member 2
chr10_+_35416089	1.326		CREM	cAMP responsive element modulator
chr3_+_151986731	1.321		MBNL1	muscleblind-like (Drosophila)
chr13_-_99630243	1.321	NM_001130048 NM_001130050	DOCK9	dedicator of cytokinesis 9
chrX_-_99891690	1.313	NM_003270	TSPAN6	tetraspanin 6
chr12_-_9268513	1.309		A2M	alpha-2-macroglobulin
chr12_-_9268522	1.296	NM_000014	A2M	alpha-2-macroglobulin
chr12_-_9268440	1.261		A2M	alpha-2-macroglobulin
chrX_-_117107700	1.260	NM_033495 NM_001168300	KLHL13	kelch-like 13 (Drosophila)
chr3_+_20081523	1.254	NM_003884	KAT2B	K(lysine) acetyltransferase 2B
chr5_-_100238870	1.252	NM_175052 NM_005668	ST8SIA4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr12_-_48963802	1.247	NM_002289	LALBA	lactalbumin, alpha-
chr14_-_92414004	1.240	NM_006329	FBLN5	fibulin 5
chr14_-_89883306	1.234	NM_005197	FOXN3	forkhead box N3
chr4_-_138453628	1.233	NM_019035	PCDH18	protocadherin 18
chr1_-_182357871	1.233		GLUL	glutamate-ammonia ligase
chr8_-_124553448	1.224	NM_001242463 NM_058229	FBXO32	F-box protein 32
chr11_-_119234628	1.219		USP2	ubiquitin specific peptidase 2
chr9_+_82187469	1.219		TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_+_66797775	1.217	NM_001037339	PDE4B	phosphodiesterase 4B, cAMP-specific
chr14_-_92413738	1.191		FBLN5	fibulin 5
chr15_-_82336880	1.190		MEX3B	mex-3 homolog B (C. elegans)
chr4_+_78079302	1.185		CCNG2	cyclin G2
chr14_+_77228132	1.184	NM_014909	VASH1	vasohibin 1
chr2_+_109271267	1.173	NM_001193485	LIMS1	LIM and senescent cell antigen-like domains 1
chr6_+_84569427	1.172		CYB5R4	cytochrome b5 reductase 4
chr8_-_38325524	1.166		FGFR1	fibroblast growth factor receptor 1
chr12_+_14538232	1.164		ATF7IP	activating transcription factor 7 interacting protein
chr10_+_18948276	1.160	NM_178815	ARL5B	ADP-ribosylation factor-like 5B
chr8_-_93115453	1.152	NM_001198633 NM_175634	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr16_+_30389632	1.149	NM_001214906 NM_001214907	ZNF48	zinc finger protein 48
chrX_-_117119282	1.138	NM_001168299	KLHL13	kelch-like 13 (Drosophila)
chr8_-_6420454	1.136	NM_001118887 NM_001118888 NM_001147	ANGPT2	angiopoietin 2
chr1_+_228337414	1.109	NM_020435	GJC2	gap junction protein, gamma 2, 47kDa
chr14_+_63671101	1.109	NM_020663	RHOJ	ras homolog gene family, member J
chr6_+_144612872	1.108	NM_007124	UTRN	utrophin
chr11_-_66445218	1.107	NM_031492	RBM4B	RNA binding motif protein 4B
chr6_+_119215240	1.104	NM_014034	ASF1A	ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr10_+_35426709	1.104	NM_183011 NM_183012	CREM	cAMP responsive element modulator
chr2_+_203499819	1.099	NM_173511	FAM117B	family with sequence similarity 117, member B
chr8_-_93075190	1.098	NM_004349	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_-_8733893	1.098	NM_001040712 NM_001171025 NM_130391 NM_130392 NM_130393	PTPRD	protein tyrosine phosphatase, receptor type, D
chr15_-_70994608	1.096	NM_001008224	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats
chr1_+_82266081	1.094	NM_012302	LPHN2	latrophilin 2
chr2_-_26205327	1.088		KIF3C	kinesin family member 3C
chr20_-_45985411	1.080	NM_012408 NM_183047 NM_183048	ZMYND8	zinc finger, MYND-type containing 8
chr1_+_84630374	1.079		PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr5_+_138677570	1.076		PAIP2	poly(A) binding protein interacting protein 2
chr5_+_138677546	1.071		PAIP2	poly(A) binding protein interacting protein 2
chr2_-_160472960	1.066	NM_013450	BAZ2B	bromodomain adjacent to zinc finger domain, 2B
chrX_+_135251795	1.065	NM_001167819	FHL1	four and a half LIM domains 1
chr12_-_9268475	1.058		A2M	alpha-2-macroglobulin
chr1_+_90098693	1.054		LRRC8C	leucine rich repeat containing 8 family, member C
chr7_+_116312412	1.046	NM_000245 NM_001127500	MET	met proto-oncogene (hepatocyte growth factor receptor)
chr20_+_11898536	1.042	NM_014962	BTBD3	BTB (POZ) domain containing 3
chr4_+_55523906	1.035	NM_000222 NM_001093772	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr19_-_14260728	1.034		LPHN1	latrophilin 1
chr5_+_57878901	1.032	NM_138453	RAB3C	RAB3C, member RAS oncogene family
chr1_+_212475147	1.031	NM_001199756	PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha
chrX_-_10645726	1.012	NM_001098624	MID1	midline 1 (Opitz/BBB syndrome)
chr6_+_116832807	1.011	NM_153711	FAM26E	family with sequence similarity 26, member E
chr12_+_9142136	0.987	NM_005810	KLRG1	killer cell lectin-like receptor subfamily G, member 1
chr5_-_95158365	0.987		GLRX	glutaredoxin (thioltransferase)
chr20_+_30598244	0.986	NM_080625	C20orf160	chromosome 20 open reading frame 160
chr19_+_45971249	0.986	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr9_-_126030854	0.984	NM_001171137	STRBP	spermatid perinuclear RNA binding protein
chr8_-_93107643	0.979		RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_-_66445318	0.978		RBM4B	RNA binding motif protein 4B
chr18_-_52988916	0.977	NM_001243234 NM_001243235	TCF4	transcription factor 4
chr10_-_116444374	0.977	NM_001003407 NM_001003408	ABLIM1	actin binding LIM protein 1
chr9_-_16727887	0.976		BNC2	basonuclin 2
chr1_+_66458389	0.976	NM_001037340	PDE4B	phosphodiesterase 4B, cAMP-specific
chr9_+_91003238	0.972	NM_006717	SPIN1	spindlin 1
chr8_-_38326115	0.972		FGFR1	fibroblast growth factor receptor 1
chr5_-_95158465	0.970	NM_001118890 NM_001243658 NM_001243659 NM_002064	GLRX	glutaredoxin (thioltransferase)
chrX_+_135251454	0.966	NM_001159704	FHL1	four and a half LIM domains 1
chr13_+_58205788	0.965	NM_001040429	PCDH17	protocadherin 17
chr5_-_111092865	0.964		C5orf13	chromosome 5 open reading frame 13
chr1_+_90098643	0.962	NM_032270	LRRC8C	leucine rich repeat containing 8 family, member C
chr1_-_234743488	0.960		IRF2BP2	interferon regulatory factor 2 binding protein 2
chr11_+_129991582	0.959		APLP2	amyloid beta (A4) precursor-like protein 2
chr14_+_91580713	0.958		C14orf159	chromosome 14 open reading frame 159
chr9_+_82187599	0.954		TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr6_+_153019029	0.954	NM_025107	MYCT1	myc target 1
chr10_-_88717319	0.949	NM_024756	MMRN2	multimerin 2
chr7_+_94297448	0.948		PEG10	paternally expressed 10
chr7_-_86688944	0.943	NM_001142749	KIAA1324L	KIAA1324-like
chr2_-_75788079	0.942	NM_001135032	FAM176A	family with sequence similarity 176, member A
chr15_+_57210972	0.929		TCF12	transcription factor 12
chr4_-_70626429	0.925	NM_014465	SULT1B1	sulfotransferase family, cytosolic, 1B, member 1
chr2_+_70056773	0.924	NM_178439	GMCL1	germ cell-less homolog 1 (Drosophila)
chr7_-_27213873	0.923	NM_018951	HOXA10	homeobox A10
chr17_+_67498391	0.920		MAP2K6	mitogen-activated protein kinase kinase 6
chr14_+_91580467	0.918		C14orf159	chromosome 14 open reading frame 159
chr6_+_122720750	0.915		HSF2	heat shock transcription factor 2
chrX_-_80457440	0.913	NM_030763	HMGN5	high mobility group nucleosome binding domain 5
chr2_+_70056920	0.911		GMCL1	germ cell-less homolog 1 (Drosophila)
chr14_+_91580967	0.890	NM_001102367	C14orf159	chromosome 14 open reading frame 159
chr15_+_66994669	0.886	NM_005585	SMAD6	SMAD family member 6
chrX_+_135229536	0.883	NM_001159702 NM_001159703 NM_001449	FHL1	four and a half LIM domains 1
chr14_-_105444693	0.882	NM_138420	AHNAK2	AHNAK nucleoprotein 2
chr8_-_93111915	0.881	NM_001198628	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr18_+_7946885	0.878		PTPRM	protein tyrosine phosphatase, receptor type, M
chr8_-_74659082	0.877	NM_001164380 NM_001164381 NM_001164382 NM_001164383 NM_001164385 NM_014393	STAU2	staufen, RNA binding protein, homolog 2 (Drosophila)
chr5_-_39425297	0.877	NM_001244871 NM_001343	DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr1_+_221052845	0.877		HLX	H2.0-like homeobox
chrX_+_10124984	0.877	NM_001830	CLCN4	chloride channel 4
chr7_-_107643330	0.877	NM_002291	LAMB1	laminin, beta 1
chr3_+_25469833	0.875	NM_000965	RARB	retinoic acid receptor, beta
chr8_-_93107881	0.871	NM_001198625 NM_001198626 NM_001198627 NM_001198631 NM_001198634 NM_001198679	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_234743820	0.864
chr3_-_141747434	0.863	NM_001178141 NM_001178142 NM_006286	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr16_+_30406432	0.857	NM_001214909	ZNF48	zinc finger protein 48
chr12_-_42877743	0.852		PRICKLE1	prickle homolog 1 (Drosophila)
chr5_-_114631964	0.852	NM_152549	CCDC112	coiled-coil domain containing 112
chr6_+_89790464	0.851		PNRC1	proline-rich nuclear receptor coactivator 1
chr7_+_115850546	0.850	NM_015641	TES	testis derived transcript (3 LIM domains)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
3.02	1.21e-09	GO:0007156	homophilic cell adhesion
1.27	3.23e-06	GO:0007275	multicellular organismal development
1.25	7.36e-06	GO:0032502	developmental process
1.14	1.84e-05	GO:0065007	biological regulation
1.27	1.76e-04	GO:0048731	system development
1.24	5.26e-04	GO:0048856	anatomical structure development
1.08	5.39e-04	GO:0009987	cellular process
1.14	6.51e-04	GO:0050794	regulation of cellular process
1.89	8.65e-04	GO:0016337	cell-cell adhesion
1.35	3.89e-03	GO:0007399	nervous system development
1.65	4.57e-03	GO:0006325	chromatin organization
1.15	7.88e-03	GO:0032501	multicellular organismal process
1.12	8.88e-03	GO:0050789	regulation of biological process
1.51	3.80e-02	GO:0051276	chromosome organization
1.67	4.03e-02	GO:0016568	chromatin modification

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.18	2.38e-06	GO:0005634	nucleus
2.58	1.62e-04	GO:0005925	focal adhesion
2.44	4.23e-04	GO:0030055	cell-substrate junction
2.46	5.40e-04	GO:0005924	cell-substrate adherens junction
2.10	8.62e-04	GO:0070161	anchoring junction
2.16	9.49e-04	GO:0005912	adherens junction
1.06	2.59e-03	GO:0005622	intracellular
1.80	1.05e-02	GO:0016323	basolateral plasma membrane
1.06	1.11e-02	GO:0044424	intracellular part
3.25	2.98e-02	GO:0042641	actomyosin

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.08	2.98e-05	GO:0005488	binding
1.28	2.14e-04	GO:0003677	DNA binding
1.21	7.32e-04	GO:0003676	nucleic acid binding
1.19	1.20e-03	GO:0046872	metal ion binding
1.19	1.30e-03	GO:0043169	cation binding
1.18	1.77e-03	GO:0043167	ion binding
1.11	4.59e-03	GO:0005515	protein binding
1.46	6.15e-03	GO:0019899	enzyme binding
1.47	1.16e-02	GO:0005509	calcium ion binding
1.50	2.24e-02	GO:0008092	cytoskeletal protein binding