Motif ID: SP1.p2

Z-value: 1.470


Transcription factors associated with SP1.p2:

Gene SymbolEntrez IDGene Name
SP1 6667 Sp1 transcription factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
SP1chr12_+_53774422-0.291.6e-01Click!


Activity profile for motif SP1.p2.

activity profile for motif SP1.p2


Sorted Z-values histogram for motif SP1.p2

Sorted Z-values for motif SP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SP1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_37137882 3.681 NM_001243186
NM_002648
 PIM1

pim-1 oncogene

chr2_-_220252569 3.545 DNPEP
aspartyl aminopeptidase
chr16_+_11762235 3.246 NM_003498
 SNN
stannin
chr2_-_220252627 2.942 NM_012100
 DNPEP
aspartyl aminopeptidase
chr6_+_4776826 2.854 CDYL
chromodomain protein, Y-like
chr10_+_104155431 2.760 NM_002502
 NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr21_+_44073650 2.635 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
 PDE9A



















phosphodiesterase 9A



















chr19_+_45504686 2.529 NM_006509
 RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr9_-_38069082 2.461 SHB
Src homology 2 domain containing adaptor protein B
chr5_+_118604417 2.408 NM_001077654
 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr21_+_43639202 2.267 NM_004915
NM_016818
 ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr6_+_4776641 2.242 NM_004824
 CDYL
chromodomain protein, Y-like
chr7_+_73703704 2.227 NM_003388
NM_032421
 CLIP2

CAP-GLY domain containing linker protein 2

chr2_-_220252513 2.217 DNPEP
aspartyl aminopeptidase
chr4_-_177713664 2.124 NM_005429
 VEGFC
vascular endothelial growth factor C
chr15_+_67358161 1.981 SMAD3
SMAD family member 3
chr6_+_14118002 1.906 CD83
CD83 molecule
chr11_-_125933186 1.881 NM_001243597
NM_016952
 CDON

Cdon homolog (mouse)

chr10_-_101380160 1.854 SLC25A28
solute carrier family 25, member 28
chr1_+_955609 1.841 AGRN
agrin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 101 entries
enrichment   p-value GO term description
1.54 4.73e-03 GO:0042176 regulation of protein catabolic process
1.47 6.16e-03 GO:0042692 muscle cell differentiation
1.35 1.24e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.34 1.55e-03 GO:0061061 muscle structure development
1.30 1.17e-02 GO:0048285 organelle fission
1.30 3.41e-02 GO:0010608 posttranscriptional regulation of gene expression
1.28 5.29e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.28 4.73e-02 GO:0000087 M phase of mitotic cell cycle
1.26 1.49e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.26 1.29e-03 GO:0031175 neuron projection development
1.26 1.40e-03 GO:0048858 cell projection morphogenesis
1.26 6.44e-03 GO:0048812 neuron projection morphogenesis
1.26 4.77e-02 GO:0051301 cell division
1.25 2.36e-03 GO:0032990 cell part morphogenesis
1.25 2.97e-02 GO:0007409 axonogenesis
1.23 3.69e-03 GO:0000278 mitotic cell cycle
1.23 4.87e-03 GO:0071822 protein complex subunit organization
1.23 4.91e-03 GO:0000902 cell morphogenesis
1.22 2.93e-03 GO:0032989 cellular component morphogenesis
1.22 3.62e-03 GO:0051726 regulation of cell cycle

Gene overrepresentation in compartment category:

Showing 1 to 20 of 35 entries
enrichment   p-value GO term description
1.32 4.20e-02 GO:0005819 spindle
1.24 8.44e-06 GO:0031967 organelle envelope
1.24 8.71e-04 GO:0030529 ribonucleoprotein complex
1.23 9.05e-06 GO:0031975 envelope
1.23 4.99e-03 GO:0005740 mitochondrial envelope
1.22 5.23e-05 GO:0044451 nucleoplasm part
1.22 2.09e-02 GO:0031966 mitochondrial membrane
1.21 5.57e-04 GO:0015630 microtubule cytoskeleton
1.20 3.99e-15 GO:0005829 cytosol
1.20 2.47e-08 GO:0005654 nucleoplasm
1.19 7.55e-13 GO:0044428 nuclear part
1.18 5.88e-10 GO:0031981 nuclear lumen
1.18 1.18e-02 GO:0044429 mitochondrial part
1.16 1.97e-09 GO:0031974 membrane-enclosed lumen
1.16 5.50e-09 GO:0070013 intracellular organelle lumen
1.15 2.39e-08 GO:0043233 organelle lumen
1.15 1.04e-02 GO:0005794 Golgi apparatus
1.14 1.62e-23 GO:0005634 nucleus
1.14 2.40e-03 GO:0005739 mitochondrion
1.13 6.08e-40 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
1.54 1.26e-02 GO:0031625 ubiquitin protein ligase binding
1.38 3.41e-02 GO:0008022 protein C-terminus binding
1.32 1.75e-04 GO:0003779 actin binding
1.30 3.58e-07 GO:0008092 cytoskeletal protein binding
1.25 2.85e-03 GO:0019904 protein domain specific binding
1.24 3.96e-02 GO:0003712 transcription cofactor activity
1.23 3.29e-05 GO:0019899 enzyme binding
1.23 5.00e-02 GO:0000988 protein binding transcription factor activity
1.23 5.00e-02 GO:0000989 transcription factor binding transcription factor activity
1.20 1.61e-03 GO:0042802 identical protein binding
1.18 8.43e-03 GO:0016301 kinase activity
1.18 2.85e-02 GO:0046983 protein dimerization activity
1.17 3.98e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.16 2.38e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.15 1.73e-02 GO:0030528 transcription regulator activity
1.14 4.45e-37 GO:0005515 protein binding
1.14 4.13e-07 GO:0000166 nucleotide binding
1.12 2.03e-03 GO:0017076 purine nucleotide binding
1.12 2.10e-03 GO:0032553 ribonucleotide binding
1.12 2.10e-03 GO:0032555 purine ribonucleotide binding