Motif ID: SP1.p2

Z-value: 1.470


Transcription factors associated with SP1.p2:

Gene SymbolEntrez IDGene Name
SP1 6667 Sp1 transcription factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
SP1chr12_+_53774422-0.291.6e-01Click!


Activity profile for motif SP1.p2.

activity profile for motif SP1.p2


Sorted Z-values histogram for motif SP1.p2

Sorted Z-values for motif SP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_37137882 3.681 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr2_-_220252569 3.545 DNPEP
aspartyl aminopeptidase
chr16_+_11762235 3.246 NM_003498
SNN
stannin
chr2_-_220252627 2.942 NM_012100
DNPEP
aspartyl aminopeptidase
chr6_+_4776826 2.854 CDYL
chromodomain protein, Y-like
chr10_+_104155431 2.760 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr21_+_44073650 2.635 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr19_+_45504686 2.529 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr9_-_38069082 2.461 SHB
Src homology 2 domain containing adaptor protein B
chr5_+_118604417 2.408 NM_001077654
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr21_+_43639202 2.267 NM_004915
NM_016818
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr6_+_4776641 2.242 NM_004824
CDYL
chromodomain protein, Y-like
chr7_+_73703704 2.227 NM_003388
NM_032421
CLIP2

CAP-GLY domain containing linker protein 2

chr2_-_220252513 2.217 DNPEP
aspartyl aminopeptidase
chr4_-_177713664 2.124 NM_005429
VEGFC
vascular endothelial growth factor C
chr15_+_67358161 1.981 SMAD3
SMAD family member 3
chr6_+_14118002 1.906 CD83
CD83 molecule
chr11_-_125933186 1.881 NM_001243597
NM_016952
CDON

Cdon homolog (mouse)

chr10_-_101380160 1.854 SLC25A28
solute carrier family 25, member 28
chr1_+_955609 1.841 AGRN
agrin
chr5_+_118604504 1.837 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr4_-_2758018 1.796 NM_024309
TNIP2
TNFAIP3 interacting protein 2
chr8_-_80679897 1.769 NM_001040708
NM_012258
HEY1

hairy/enhancer-of-split related with YRPW motif 1

chr9_-_95896498 1.751 NM_004148
NINJ1
ninjurin 1
chr19_-_47734215 1.721 NM_014417
BBC3
BCL2 binding component 3
chr16_+_50776012 1.716 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr6_-_29595746 1.684 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr17_-_1083008 1.683 NM_021962
ABR
active BCR-related gene
chr16_+_50775960 1.676 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr5_-_16936290 1.662 MYO10
myosin X
chr15_+_67358194 1.644 NM_005902
SMAD3
SMAD family member 3
chr1_+_955468 1.640 NM_198576
AGRN
agrin
chr6_-_109804322 1.629 ZBTB24
zinc finger and BTB domain containing 24
chr10_-_101380217 1.607 NM_031212
SLC25A28
solute carrier family 25, member 28
chr1_+_2518071 1.594 NM_001195736
NM_001195737
NM_001195738
NM_001195740
NM_001195741
NM_152371
FAM213B





family with sequence similarity 213, member B





chr9_+_140500148 1.582 ARRDC1
arrestin domain containing 1
chr11_-_64645925 1.582 EHD1
EH-domain containing 1
chr22_+_29279573 1.556 NM_001206998
ZNRF3
zinc and ring finger 3
chr22_-_43116796 1.526 NM_017436
A4GALT
alpha 1,4-galactosyltransferase
chrX_+_9432980 1.492 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr8_+_142138684 1.490 NM_014957
DENND3
DENN/MADD domain containing 3
chr10_+_135192694 1.470 NM_152911
NM_207127
NM_207128
PAOX


polyamine oxidase (exo-N4-amino)


chr20_+_56884839 1.465 RAB22A
RAB22A, member RAS oncogene family
chr20_+_56885027 1.464 RAB22A
RAB22A, member RAS oncogene family
chr16_+_2039945 1.451 NM_004209
SYNGR3
synaptogyrin 3
chr7_-_25019625 1.446 NM_015550
NM_145320
NM_145321
NM_145322
OSBPL3



oxysterol binding protein-like 3



chr2_+_234263141 1.409 NM_152879
DGKD
diacylglycerol kinase, delta 130kDa
chr9_+_140500136 1.377 ARRDC1
arrestin domain containing 1
chr5_-_131826426 1.367 NM_002198
IRF1
interferon regulatory factor 1
chr1_+_212781969 1.365 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr14_-_104313730 1.359 NM_015316
PPP1R13B
protein phosphatase 1, regulatory subunit 13B
chr8_-_37756971 1.357 NM_001002814
NM_025151
RAB11FIP1

RAB11 family interacting protein 1 (class I)

chr3_-_127541160 1.350 NM_007283
MGLL
monoglyceride lipase
chr3_-_45267804 1.309 NM_015444
TMEM158
transmembrane protein 158 (gene/pseudogene)
chr1_+_2518464 1.307 FAM213B
family with sequence similarity 213, member B
chr5_+_10564431 1.304 NM_001164440
ANKRD33B
ankyrin repeat domain 33B
chr11_-_3862137 1.289 RHOG
ras homolog gene family, member G (rho G)
chr15_-_23086290 1.272 NM_144599
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr21_-_45660841 1.269 ICOSLG
inducible T-cell co-stimulator ligand
chr15_-_100273540 1.261 LYSMD4
LysM, putative peptidoglycan-binding, domain containing 4
chr19_-_50432952 1.259 NM_016553
NUP62
nucleoporin 62kDa
chr10_-_101380086 1.257 SLC25A28
solute carrier family 25, member 28
chr22_-_50946020 1.256 LMF2
lipase maturation factor 2
chr12_-_121734543 1.255 NM_172226
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr16_-_402617 1.239 NM_003502
NM_181050
AXIN1

axin 1

chr19_+_54371150 1.235 MYADM
myeloid-associated differentiation marker
chr18_+_77155927 1.233 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr7_-_98741375 1.229 SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr16_-_3285359 1.229 NM_001145448
NM_198088
NM_001145446
NM_198087
ZNF200



zinc finger protein 200



chr9_+_35732207 1.227 NM_006368
CREB3
cAMP responsive element binding protein 3
chr17_-_74497406 1.219 NM_024599
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr18_+_77155966 1.211 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr6_+_149639054 1.209 TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr10_+_74451838 1.201 NM_138357
MCU
mitochondrial calcium uniporter
chr5_+_102594406 1.199 NM_033211
C5orf30
chromosome 5 open reading frame 30
chr5_-_1112106 1.191 NM_006598
SLC12A7
solute carrier family 12 (potassium/chloride transporters), member 7
chr19_-_50832633 1.187 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr11_-_575848 1.186 LOC143666
uncharacterized LOC143666
chr2_+_64681270 1.179 NM_014181
LGALSL
lectin, galactoside-binding-like
chr6_-_160114318 1.178 NM_000636
NM_001024465
NM_001024466
SOD2


superoxide dismutase 2, mitochondrial


chr7_-_22396511 1.178 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr11_-_66234176 1.175 MRPL11
mitochondrial ribosomal protein L11
chr9_+_140500054 1.171 NM_152285
ARRDC1
arrestin domain containing 1
chr21_-_45660699 1.168 NM_015259
ICOSLG
inducible T-cell co-stimulator ligand
chr17_+_36861857 1.167 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr6_+_144471631 1.155 NM_003764
STX11
syntaxin 11
chr11_-_57092283 1.151 NM_033396
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr15_-_75743776 1.149 NM_015477
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr17_+_7255427 1.148 KCTD11
potassium channel tetramerisation domain containing 11
chr8_-_141645603 1.130 NM_001164623
NM_012154
EIF2C2

eukaryotic translation initiation factor 2C, 2

chr9_+_140500097 1.130 ARRDC1
arrestin domain containing 1
chr22_+_45705965 1.130 FAM118A
family with sequence similarity 118, member A
chr11_+_118307072 1.129 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr11_-_64646053 1.121 NM_006795
EHD1
EH-domain containing 1
chr3_-_52443893 1.112 NM_004656
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr6_-_30654978 1.110 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr3_-_45267620 1.109 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr12_-_121734474 1.104 CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr21_+_43639930 1.102 NM_207174
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr19_-_1863425 1.102 KLF16
Kruppel-like factor 16
chr8_+_23386362 1.100 NM_016612
SLC25A37
solute carrier family 25, member 37
chr6_+_160148608 1.099 NM_152857
WTAP
Wilms tumor 1 associated protein
chr19_+_51815095 1.090 NM_001101372
IGLON5
IgLON family member 5
chr19_-_2015628 1.088 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr19_-_55866063 1.077 NM_144613
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr3_+_122399665 1.073 NM_017554
PARP14
poly (ADP-ribose) polymerase family, member 14
chr9_-_38069207 1.066 NM_003028
SHB
Src homology 2 domain containing adaptor protein B
chr3_-_52444016 1.066 BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr17_-_17726855 1.058 SREBF1
sterol regulatory element binding transcription factor 1
chr9_+_100174179 1.043 NM_014290
TDRD7
tudor domain containing 7
chr7_-_1499107 1.041 NM_182924
MICALL2
MICAL-like 2
chr5_+_17217474 1.037 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr1_-_935469 1.030 NM_001142467
NM_021170
HES4

hairy and enhancer of split 4 (Drosophila)

chr5_-_32313069 1.030 NM_001040446
MTMR12
myotubularin related protein 12
chr22_+_45705766 1.026 NM_017911
FAM118A
family with sequence similarity 118, member A
chr1_+_206858308 1.025 NM_004759
NM_032960
MAPKAPK2

mitogen-activated protein kinase-activated protein kinase 2

chr6_+_138188352 1.021 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr15_-_100273620 1.021 NM_152449
LYSMD4
LysM, putative peptidoglycan-binding, domain containing 4
chr5_-_32312943 1.019 MTMR12
myotubularin related protein 12
chr21_-_45759234 1.015 C21orf2
chromosome 21 open reading frame 2
chr6_+_14117857 1.013 NM_001040280
NM_004233
CD83

CD83 molecule

chr6_+_31126340 1.012 TCF19
transcription factor 19
chr6_-_13408368 1.010 NM_001242630
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr7_+_28448970 1.009 LOC401317
uncharacterized LOC401317
chr19_+_50879681 1.007 NM_007121
NR1H2
nuclear receptor subfamily 1, group H, member 2
chr20_+_61427804 1.004 NM_018270
C20orf20
chromosome 20 open reading frame 20
chr1_+_212782103 1.004 ATF3
activating transcription factor 3
chr6_+_31126114 1.002 NM_001077511
NM_007109
TCF19

transcription factor 19

chr15_-_68521921 1.000 NM_017882
CLN6
ceroid-lipofuscinosis, neuronal 6, late infantile, variant
chr14_+_21538339 0.996 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr2_+_234263153 0.993 DGKD
diacylglycerol kinase, delta 130kDa
chr11_+_65292576 0.991 SCYL1
SCY1-like 1 (S. cerevisiae)
chr7_-_100487273 0.991 NM_001015072
UFSP1
UFM1-specific peptidase 1 (non-functional)
chr1_-_156721280 0.988 HDGF
hepatoma-derived growth factor
chr22_-_50946129 0.986 NM_033200
LMF2
lipase maturation factor 2
chr2_+_64681610 0.978 LGALSL
lectin, galactoside-binding-like
chr10_-_135171512 0.976 NM_001098483
NM_198472
C10orf125

chromosome 10 open reading frame 125

chr8_+_104383701 0.972 CTHRC1
collagen triple helix repeat containing 1
chr6_-_109804432 0.970 NM_001164313
NM_014797
ZBTB24

zinc finger and BTB domain containing 24

chr17_-_48207113 0.969 NM_174920
SAMD14
sterile alpha motif domain containing 14
chr20_+_30946786 0.968 ASXL1
additional sex combs like 1 (Drosophila)
chr17_+_39382878 0.967 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr6_+_37787592 0.967 ZFAND3
zinc finger, AN1-type domain 3
chr6_+_18155535 0.962 NM_153042
KDM1B
lysine (K)-specific demethylase 1B
chr19_+_6739697 0.962 NM_004240
TRIP10
thyroid hormone receptor interactor 10
chr1_-_160068359 0.961 NM_052868
IGSF8
immunoglobulin superfamily, member 8
chr6_-_160114186 0.948 SOD2
superoxide dismutase 2, mitochondrial
chr5_+_179234002 0.947 NM_001142299
SQSTM1
sequestosome 1
chr8_+_145064583 0.938 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr6_-_44233244 0.933 NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr22_-_45636760 0.933 KIAA0930
KIAA0930
chr2_-_288181 0.928 NM_001002919
FAM150B
family with sequence similarity 150, member B
chr11_-_72353435 0.928 NM_001143839
NM_001243784
PDE2A

phosphodiesterase 2A, cGMP-stimulated

chr9_-_132805256 0.927 FNBP1
formin binding protein 1
chr12_-_133306531 0.920 ANKLE2
ankyrin repeat and LEM domain containing 2
chr20_+_35974458 0.920 NM_198291
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr17_-_53499055 0.919 NM_012329
MMD
monocyte to macrophage differentiation-associated
chr19_+_54372659 0.919 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr6_-_30655078 0.912 NM_001134870
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr7_+_55086922 0.910 EGFR
epidermal growth factor receptor
chr10_+_82214066 0.907 TSPAN14
tetraspanin 14
chr17_+_36861398 0.907 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr2_+_85360373 0.906 NM_031283
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr10_-_105614952 0.905 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr17_-_80606095 0.905 NM_019613
WDR45L
WDR45-like
chr14_-_21566728 0.900 NM_016423
ZNF219
zinc finger protein 219
chr1_+_166808721 0.899 NM_017542
POGK
pogo transposable element with KRAB domain
chr9_+_100174369 0.896 TDRD7
tudor domain containing 7
chr1_-_161102210 0.896 NM_001039712
DEDD
death effector domain containing
chr4_-_2757750 0.891 NM_001161527
TNIP2
TNFAIP3 interacting protein 2
chr6_-_13486986 0.891 GFOD1
glucose-fructose oxidoreductase domain containing 1
chr14_-_21566497 0.890 ZNF219
zinc finger protein 219
chr17_+_7255207 0.884 NM_001002914
KCTD11
potassium channel tetramerisation domain containing 11
chr1_-_161102367 0.883 DEDD
death effector domain containing
chr10_+_82213892 0.880 NM_001128309
NM_030927
TSPAN14

tetraspanin 14

chr8_-_494834 0.880 C8orf42
chromosome 8 open reading frame 42
chr1_+_100111430 0.877 NM_017734
PALMD
palmdelphin
chr4_-_37687932 0.874 NM_001085399
NM_001085400
RELL1

RELT-like 1

chr12_-_50101192 0.873 NM_175736
NM_198900
FMNL3

formin-like 3

chr19_+_41725277 0.873 AXL
AXL receptor tyrosine kinase
chr17_-_80231240 0.869 CSNK1D
casein kinase 1, delta
chr19_-_55658310 0.869 TNNT1
troponin T type 1 (skeletal, slow)
chr17_-_73874634 0.861 NM_033452
TRIM47
tripartite motif containing 47
chr19_-_47922339 0.859 MEIS3
Meis homeobox 3
chr1_-_160068617 0.857 NM_001206665
IGSF8
immunoglobulin superfamily, member 8
chr19_+_47778099 0.851 NM_178511
PRR24
proline rich 24
chr12_-_124068864 0.846


chr11_+_369723 0.845 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr6_+_14117486 0.844 NM_001251901
CD83
CD83 molecule
chr19_-_10444186 0.843 NM_133452
RAVER1
ribonucleoprotein, PTB-binding 1
chr20_-_62462568 0.841 ZBTB46
zinc finger and BTB domain containing 46
chr22_+_38302296 0.841 MICALL1
MICAL-like 1
chr20_-_61569227 0.839 DIDO1
death inducer-obliterator 1
chr1_-_229761716 0.837 TAF5L
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr16_-_402398 0.836 AXIN1
axin 1
chr19_+_10197023 0.836 C19orf66
chromosome 19 open reading frame 66
chr1_-_36851484 0.835 NM_032017
STK40
serine/threonine kinase 40
chr3_-_64673330 0.834 NM_182920
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr4_+_38665587 0.831 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr7_+_45039777 0.830 NM_001167934
NM_001167935
NM_031443
CCM2


cerebral cavernous malformation 2



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 9.60e-26 GO:0009987 cellular process
1.11 1.54e-15 GO:0044237 cellular metabolic process
1.16 2.30e-15 GO:0016043 cellular component organization
1.10 1.46e-14 GO:0050794 regulation of cellular process
1.16 2.26e-14 GO:0071840 cellular component organization or biogenesis
1.18 4.01e-14 GO:0071842 cellular component organization at cellular level
1.09 4.18e-14 GO:0065007 biological regulation
1.09 7.41e-14 GO:0050789 regulation of biological process
1.09 1.00e-12 GO:0008152 metabolic process
1.17 2.03e-12 GO:0071841 cellular component organization or biogenesis at cellular level
1.13 2.26e-12 GO:0044260 cellular macromolecule metabolic process
1.14 1.55e-11 GO:0080090 regulation of primary metabolic process
1.14 4.38e-11 GO:0031323 regulation of cellular metabolic process
1.09 2.08e-10 GO:0044238 primary metabolic process
1.15 5.30e-10 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14 1.37e-09 GO:0034641 cellular nitrogen compound metabolic process
1.13 1.67e-09 GO:0060255 regulation of macromolecule metabolic process
1.12 1.68e-09 GO:0019222 regulation of metabolic process
1.10 2.84e-09 GO:0043170 macromolecule metabolic process
1.19 8.73e-09 GO:0006996 organelle organization
1.13 2.62e-08 GO:0006807 nitrogen compound metabolic process
1.11 9.83e-07 GO:0032502 developmental process
1.13 2.08e-06 GO:0051171 regulation of nitrogen compound metabolic process
1.13 3.57e-06 GO:0010468 regulation of gene expression
1.13 4.20e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14 5.22e-06 GO:0048523 negative regulation of cellular process
1.16 6.92e-06 GO:0010467 gene expression
1.11 1.02e-05 GO:0007275 multicellular organismal development
1.14 1.08e-05 GO:0090304 nucleic acid metabolic process
1.16 1.19e-05 GO:0016070 RNA metabolic process
1.26 1.49e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.13 2.12e-05 GO:0048522 positive regulation of cellular process
1.13 2.76e-05 GO:0048519 negative regulation of biological process
1.20 3.23e-05 GO:0032268 regulation of cellular protein metabolic process
1.20 3.55e-05 GO:0051246 regulation of protein metabolic process
1.11 3.91e-05 GO:0048856 anatomical structure development
1.28 5.29e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.13 5.84e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.14 6.21e-05 GO:0048869 cellular developmental process
1.16 9.02e-05 GO:0007399 nervous system development
1.12 9.55e-05 GO:0044267 cellular protein metabolic process
1.12 1.61e-04 GO:0048518 positive regulation of biological process
1.11 1.78e-04 GO:0048731 system development
1.20 1.94e-04 GO:0010605 negative regulation of macromolecule metabolic process
1.13 1.95e-04 GO:0030154 cell differentiation
1.12 2.07e-04 GO:0031326 regulation of cellular biosynthetic process
1.15 2.81e-04 GO:0023051 regulation of signaling
1.19 3.27e-04 GO:0007049 cell cycle
1.12 3.64e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.11 4.30e-04 GO:0009889 regulation of biosynthetic process
1.10 5.19e-04 GO:0051179 localization
1.20 5.24e-04 GO:0048468 cell development
1.12 6.09e-04 GO:0051252 regulation of RNA metabolic process
1.19 6.72e-04 GO:0009892 negative regulation of metabolic process
1.20 7.52e-04 GO:0031324 negative regulation of cellular metabolic process
1.21 7.83e-04 GO:0022402 cell cycle process
1.26 1.29e-03 GO:0031175 neuron projection development
1.26 1.40e-03 GO:0048858 cell projection morphogenesis
1.34 1.55e-03 GO:0061061 muscle structure development
1.19 1.95e-03 GO:0022008 neurogenesis
1.25 2.36e-03 GO:0032990 cell part morphogenesis
1.15 2.67e-03 GO:0009966 regulation of signal transduction
1.21 2.92e-03 GO:0022403 cell cycle phase
1.22 2.93e-03 GO:0032989 cellular component morphogenesis
1.10 2.97e-03 GO:0051234 establishment of localization
1.22 3.62e-03 GO:0051726 regulation of cell cycle
1.23 3.69e-03 GO:0000278 mitotic cell cycle
1.10 4.38e-03 GO:0006810 transport
1.20 4.42e-03 GO:0046907 intracellular transport
1.19 4.65e-03 GO:0033554 cellular response to stress
1.54 4.73e-03 GO:0042176 regulation of protein catabolic process
1.16 4.83e-03 GO:0044248 cellular catabolic process
1.23 4.87e-03 GO:0071822 protein complex subunit organization
1.23 4.91e-03 GO:0000902 cell morphogenesis
1.08 5.66e-03 GO:0023052 signaling
1.11 5.84e-03 GO:0006355 regulation of transcription, DNA-dependent
1.10 6.10e-03 GO:0019538 protein metabolic process
1.47 6.16e-03 GO:0042692 muscle cell differentiation
1.26 6.44e-03 GO:0048812 neuron projection morphogenesis
1.13 6.73e-03 GO:0034645 cellular macromolecule biosynthetic process
1.14 7.10e-03 GO:0009653 anatomical structure morphogenesis
1.09 7.53e-03 GO:0007165 signal transduction
1.18 9.76e-03 GO:0048699 generation of neurons
1.30 1.17e-02 GO:0048285 organelle fission
1.35 1.24e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.10 1.44e-02 GO:0044249 cellular biosynthetic process
1.12 1.63e-02 GO:0006464 protein modification process
1.20 1.80e-02 GO:0030182 neuron differentiation
1.13 1.80e-02 GO:0009059 macromolecule biosynthetic process
1.17 1.85e-02 GO:0032774 RNA biosynthetic process
1.21 2.49e-02 GO:0048666 neuron development
1.16 2.67e-02 GO:0010646 regulation of cell communication
1.25 2.97e-02 GO:0007409 axonogenesis
1.19 3.12e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.13 3.18e-02 GO:0009056 catabolic process
1.30 3.41e-02 GO:0010608 posttranscriptional regulation of gene expression
1.20 3.46e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.20 3.55e-02 GO:0030030 cell projection organization
1.15 3.55e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.28 4.73e-02 GO:0000087 M phase of mitotic cell cycle
1.26 4.77e-02 GO:0051301 cell division

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 2.29e-56 GO:0005622 intracellular
1.10 5.08e-55 GO:0044424 intracellular part
1.13 6.08e-40 GO:0005737 cytoplasm
1.10 1.14e-36 GO:0043229 intracellular organelle
1.10 1.29e-36 GO:0043226 organelle
1.11 1.30e-35 GO:0043227 membrane-bounded organelle
1.11 4.08e-35 GO:0043231 intracellular membrane-bounded organelle
1.14 1.62e-23 GO:0005634 nucleus
1.12 3.30e-20 GO:0044444 cytoplasmic part
1.12 1.16e-16 GO:0044446 intracellular organelle part
1.11 3.54e-16 GO:0044422 organelle part
1.20 3.99e-15 GO:0005829 cytosol
1.03 4.72e-14 GO:0044464 cell part
1.03 5.57e-14 GO:0005623 cell
1.19 7.55e-13 GO:0044428 nuclear part
1.18 5.88e-10 GO:0031981 nuclear lumen
1.16 1.97e-09 GO:0031974 membrane-enclosed lumen
1.16 5.50e-09 GO:0070013 intracellular organelle lumen
1.15 2.39e-08 GO:0043233 organelle lumen
1.20 2.47e-08 GO:0005654 nucleoplasm
1.10 1.82e-06 GO:0032991 macromolecular complex
1.24 8.44e-06 GO:0031967 organelle envelope
1.23 9.05e-06 GO:0031975 envelope
1.11 3.07e-05 GO:0043228 non-membrane-bounded organelle
1.11 3.07e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.22 5.23e-05 GO:0044451 nucleoplasm part
1.10 1.54e-04 GO:0043234 protein complex
1.21 5.57e-04 GO:0015630 microtubule cytoskeleton
1.24 8.71e-04 GO:0030529 ribonucleoprotein complex
1.14 2.40e-03 GO:0005739 mitochondrion
1.23 4.99e-03 GO:0005740 mitochondrial envelope
1.15 1.04e-02 GO:0005794 Golgi apparatus
1.18 1.18e-02 GO:0044429 mitochondrial part
1.22 2.09e-02 GO:0031966 mitochondrial membrane
1.32 4.20e-02 GO:0005819 spindle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 4.45e-37 GO:0005515 protein binding
1.07 2.92e-28 GO:0005488 binding
1.30 3.58e-07 GO:0008092 cytoskeletal protein binding
1.14 4.13e-07 GO:0000166 nucleotide binding
1.23 3.29e-05 GO:0019899 enzyme binding
1.10 1.49e-04 GO:0003676 nucleic acid binding
1.32 1.75e-04 GO:0003779 actin binding
1.20 1.61e-03 GO:0042802 identical protein binding
1.12 2.03e-03 GO:0017076 purine nucleotide binding
1.12 2.10e-03 GO:0032553 ribonucleotide binding
1.12 2.10e-03 GO:0032555 purine ribonucleotide binding
1.12 2.64e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.25 2.85e-03 GO:0019904 protein domain specific binding
1.06 7.31e-03 GO:0003824 catalytic activity
1.18 8.43e-03 GO:0016301 kinase activity
1.54 1.26e-02 GO:0031625 ubiquitin protein ligase binding
1.15 1.73e-02 GO:0030528 transcription regulator activity
1.16 2.38e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.18 2.85e-02 GO:0046983 protein dimerization activity
1.12 3.22e-02 GO:0030554 adenyl nucleotide binding
1.12 3.31e-02 GO:0032559 adenyl ribonucleotide binding
1.38 3.41e-02 GO:0008022 protein C-terminus binding
1.24 3.96e-02 GO:0003712 transcription cofactor activity
1.17 3.98e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.23 5.00e-02 GO:0000988 protein binding transcription factor activity
1.23 5.00e-02 GO:0000989 transcription factor binding transcription factor activity