Motif ID: SPI1.p2

Z-value: 1.356


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
SPI1chr11_-_474000960.145.1e-01Click!


Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_184943673 5.540 NM_052966
FAM129A
family with sequence similarity 129, member A
chr1_-_184943532 5.060 FAM129A
family with sequence similarity 129, member A
chr4_-_76944585 4.638 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr15_+_67358161 3.540 SMAD3
SMAD family member 3
chr6_-_31550065 3.443 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr6_-_29595746 3.105 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_-_60719116 3.019 NM_016582
SLC15A3
solute carrier family 15, member 3
chr5_+_118691692 2.817 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr15_+_67358194 2.383 NM_005902
SMAD3
SMAD family member 3
chr10_-_49812996 2.322 NM_021226
ARHGAP22
Rho GTPase activating protein 22
chr5_-_172756505 2.271 NM_003714
STC2
stanniocalcin 2
chr6_+_160148608 2.123 NM_152857
WTAP
Wilms tumor 1 associated protein
chr9_+_109625347 2.118 NM_021224
ZNF462
zinc finger protein 462
chr5_-_172755418 1.934 STC2
stanniocalcin 2
chr5_+_131409484 1.777 NM_000758
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr2_+_150187028 1.751 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr16_-_65155881 1.719 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr9_+_35732498 1.705 CREB3
cAMP responsive element binding protein 3
chr14_-_24616429 1.699 PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr4_-_185395616 1.694 NM_002199
IRF2
interferon regulatory factor 2
chr15_+_90544608 1.594 NM_198526
ZNF710
zinc finger protein 710
chr9_+_35732207 1.593 NM_006368
CREB3
cAMP responsive element binding protein 3
chr1_-_173446273 1.592 LOC100506023
uncharacterized LOC100506023
chr1_-_111743297 1.591 DENND2D
DENN/MADD domain containing 2D
chr19_-_50400131 1.566 NM_152899
IL4I1
interleukin 4 induced 1
chr17_-_45933138 1.559 NM_199262
SP6
Sp6 transcription factor
chr5_+_127419407 1.547 NM_001046
SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chrX_-_83757398 1.524 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr17_-_4167028 1.516 NM_016376
NM_020740
ANKFY1

ankyrin repeat and FYVE domain containing 1

chr21_+_26934440 1.506 MIR155HG
MIR155 host gene (non-protein coding)
chr6_-_137113166 1.505


chr12_+_121570630 1.459 NM_002562
P2RX7
purinergic receptor P2X, ligand-gated ion channel, 7
chr6_+_31553955 1.433 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr12_-_57505121 1.423 STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr4_-_120549115 1.387 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr16_+_56485423 1.373 NM_018233
OGFOD1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr22_-_50964856 1.372 NM_001169109
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr20_+_45523523 1.357 EYA2
eyes absent homolog 2 (Drosophila)
chr4_-_185747051 1.340 ACSL1
acyl-CoA synthetase long-chain family member 1
chr15_+_75074714 1.337 CSK
c-src tyrosine kinase
chr9_+_35732629 1.336 CREB3
cAMP responsive element binding protein 3
chr6_+_26368405 1.296 NM_001197246
BTN3A2
butyrophilin, subfamily 3, member A2
chr12_-_57505176 1.293 NM_001178078
NM_001178080
NM_001178081
NM_003153
STAT6



signal transducer and activator of transcription 6, interleukin-4 induced



chr15_+_75074417 1.291 NM_001127190
NM_004383
CSK

c-src tyrosine kinase

chr7_+_18126543 1.272 NM_001204144
HDAC9
histone deacetylase 9
chr21_+_27012067 1.265 JAM2
junctional adhesion molecule 2
chr11_-_64647136 1.253 EHD1
EH-domain containing 1
chr5_-_172755195 1.237 STC2
stanniocalcin 2
chr4_-_146859568 1.232 NM_178835
ZNF827
zinc finger protein 827
chr17_-_74497406 1.217 NM_024599
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr12_+_21654698 1.158 NM_016072
GOLT1B
golgi transport 1B
chr20_+_53092131 1.156 NM_018431
DOK5
docking protein 5
chr12_+_102271349 1.152 DRAM1
DNA-damage regulated autophagy modulator 1
chr11_-_9225780 1.147 DENND5A
DENN/MADD domain containing 5A
chr6_-_43595046 1.146 GTPBP2
GTP binding protein 2
chr22_+_38453478 1.145 PICK1
protein interacting with PRKCA 1
chr6_-_137113602 1.143 MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr19_-_50413063 1.129 NUP62
nucleoporin 62kDa
chr12_+_21654745 1.128 GOLT1B
golgi transport 1B
chr15_+_74287132 1.124 PML
promyelocytic leukemia
chr6_-_137113529 1.122 MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr12_+_56075418 1.088 METTL7B
methyltransferase like 7B
chr20_+_45523505 1.086 EYA2
eyes absent homolog 2 (Drosophila)
chr16_+_57050985 1.079 NM_032206
NLRC5
NLR family, CARD domain containing 5
chr13_+_26828755 1.078 NM_001260
CDK8
cyclin-dependent kinase 8
chr6_+_31554475 1.073 NM_205837
LST1
leukocyte specific transcript 1
chr7_+_55086658 1.065 NM_005228
NM_201282
NM_201283
NM_201284
EGFR



epidermal growth factor receptor



chr12_-_89918531 1.051 NM_003774
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr11_-_46142955 1.051 NM_001101802
NM_016621
PHF21A

PHD finger protein 21A

chr15_+_74287148 1.050 PML
promyelocytic leukemia
chr9_+_116930778 1.036 COL27A1
collagen, type XXVII, alpha 1
chr11_-_117747331 1.023 FXYD6
FXYD domain containing ion transport regulator 6
chr1_-_161102210 1.011 NM_001039712
DEDD
death effector domain containing
chr6_-_30654978 1.011 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr7_+_21468293 1.007


chr17_+_18380097 1.005 NM_001040078
LGALS9B
LGALS9C
lectin, galactoside-binding, soluble, 9B
lectin, galactoside-binding, soluble, 9C
chr8_+_120428551 1.002 NM_002514
NOV
nephroblastoma overexpressed gene
chr6_-_32812711 0.991 NM_004159
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr10_+_101419169 0.987 NM_020354
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr16_+_56485435 0.980 OGFOD1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr1_-_156721501 0.975 NM_004494
HDGF
hepatoma-derived growth factor
chr6_-_32812409 0.969 PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr4_-_185747183 0.968 NM_001995
ACSL1
acyl-CoA synthetase long-chain family member 1
chr14_+_96671015 0.967 NM_000623
BDKRB2
bradykinin receptor B2
chr22_+_37309618 0.964 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr20_-_47894591 0.961 NM_021035
ZNFX1
zinc finger, NFX1-type containing 1
chr12_+_102271082 0.961 NM_018370
DRAM1
DNA-damage regulated autophagy modulator 1
chr6_+_37137882 0.958 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr1_+_183441445 0.955 NM_001174061
NM_173156
NM_201568
NM_201569
SMG7



smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)



chr6_+_4776826 0.950 CDYL
chromodomain protein, Y-like
chr5_-_95297424 0.946 ELL2
elongation factor, RNA polymerase II, 2
chr1_-_148176392 0.944


chr15_-_51057832 0.938 SPPL2A
signal peptide peptidase-like 2A
chr6_-_30652434 0.937 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr3_-_172428773 0.931 NM_001146276
NM_001146277
NM_001146278
NM_020792
NCEH1



neutral cholesterol ester hydrolase 1



chr17_+_36861857 0.912 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr5_+_135364583 0.910 NM_000358
TGFBI
transforming growth factor, beta-induced, 68kDa
chr12_-_49365545 0.910 NM_003394
WNT10B
wingless-type MMTV integration site family, member 10B
chr6_-_137113721 0.909 MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr1_-_120612260 0.902 NOTCH2
notch 2
chr18_+_8609670 0.901


chr17_-_41623652 0.900 NM_001079675
ETV4
ets variant 4
chr5_+_129240453 0.897 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr19_+_10196757 0.893 NM_018381
C19orf66
chromosome 19 open reading frame 66
chr15_+_74287107 0.891 PML
promyelocytic leukemia
chr17_+_25958257 0.890 LGALS9
lectin, galactoside-binding, soluble, 9
chr11_-_3862137 0.884 RHOG
ras homolog gene family, member G (rho G)
chr6_-_43595079 0.881 GTPBP2
GTP binding protein 2
chr12_-_57504935 0.878 STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr1_-_157811491 0.878 NM_005894
CD5L
CD5 molecule-like
chr5_+_52095929 0.873 PELO
pelota homolog (Drosophila)
chr10_+_111767685 0.872 NM_001121
NM_016824
ADD3

adducin 3 (gamma)

chr11_-_441956 0.871 ANO9
anoctamin 9
chr15_+_74286999 0.870 NM_002675
NM_033238
NM_033239
NM_033240
NM_033244
NM_033246
NM_033247
NM_033249
NM_033250
PML








promyelocytic leukemia








chr12_+_64238511 0.870 NM_020762
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr20_-_47894570 0.869 ZNFX1
zinc finger, NFX1-type containing 1
chr9_+_5510544 0.867 NM_025239
PDCD1LG2
programmed cell death 1 ligand 2
chr3_-_11761946 0.866 NM_014667
VGLL4
vestigial like 4 (Drosophila)
chr6_-_143266283 0.857 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr3_+_140770412 0.850 SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr2_-_11810254 0.848 NM_012344
NTSR2
neurotensin receptor 2
chr3_+_130612806 0.844 NM_001199179
NM_001001485
NM_001199183
NM_001199184
NM_001199185
NM_014382
NM_001001486
NM_001001487
ATP2C1







ATPase, Ca++ transporting, type 2C, member 1







chr10_+_81107259 0.844 PPIF
peptidylprolyl isomerase F
chr17_+_56270085 0.839 NM_000502
EPX
eosinophil peroxidase
chr2_-_153573858 0.836 NM_017892
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chrX_+_68048792 0.833 NM_004429
EFNB1
ephrin-B1
chr1_-_161102457 0.832 NM_001039711
NM_032998
DEDD

death effector domain containing

chr4_+_142557722 0.829 NM_000585
NM_172175
IL15

interleukin 15

chr17_-_41623246 0.822 NM_001986
ETV4
ets variant 4
chr16_-_67694602 0.815 NM_001082486
NM_001082487
NM_022914
ACD


adrenocortical dysplasia homolog (mouse)


chr1_-_26644755 0.814 NM_145345
UBXN11
UBX domain protein 11
chr1_-_161102367 0.813 DEDD
death effector domain containing
chr6_-_32160289 0.811 GPSM3
G-protein signaling modulator 3
chr5_+_34656367 0.808 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr11_-_117695408 0.803 NM_001680
FXYD2
FXYD domain containing ion transport regulator 2
chr14_+_24616707 0.801 RNF31
ring finger protein 31
chr14_+_55034633 0.799 SAMD4A
sterile alpha motif domain containing 4A
chr20_-_44540685 0.794 PLTP
phospholipid transfer protein
chr14_+_24616658 0.792 NM_017999
RNF31
ring finger protein 31
chr8_-_119123804 0.791 NM_000127
EXT1
exostosin 1
chr1_+_170501240 0.791 NM_001146039
NM_152281
GORAB

golgin, RAB6-interacting

chr17_+_25958245 0.788 LGALS9
lectin, galactoside-binding, soluble, 9
chr6_+_18155535 0.788 NM_153042
KDM1B
lysine (K)-specific demethylase 1B
chr1_+_183441649 0.784 SMG7
smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr17_+_25958217 0.778 LGALS9
lectin, galactoside-binding, soluble, 9
chr3_-_71294229 0.778 NM_001244814
FOXP1
forkhead box P1
chr10_-_88281486 0.777 WAPAL
wings apart-like homolog (Drosophila)
chr10_-_27149791 0.777 ABI1
abl-interactor 1
chr12_-_50101192 0.769 NM_175736
NM_198900
FMNL3

formin-like 3

chr22_+_37257004 0.769 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr19_+_48828820 0.765 EMP3
epithelial membrane protein 3
chr19_+_10196972 0.764 C19orf66
chromosome 19 open reading frame 66
chr19_+_10197023 0.762 C19orf66
chromosome 19 open reading frame 66
chr6_-_32812189 0.762 PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chrX_+_11129405 0.760 NM_001122608
NM_001171991
NM_005333
HCCS


holocytochrome c synthase


chr1_+_218518675 0.755 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr9_-_123688352 0.753 TRAF1
TNF receptor-associated factor 1
chr20_-_35580186 0.751 NM_015474
SAMHD1
SAM domain and HD domain 1
chr20_+_61436160 0.749 NM_007346
OGFR
opioid growth factor receptor
chr3_-_119812512 0.749 GSK3B
glycogen synthase kinase 3 beta
chr3_-_16555128 0.745 NM_015150
RFTN1
raftlin, lipid raft linker 1
chr12_+_54891539 0.742 NCKAP1L
NCK-associated protein 1-like
chr20_+_45523247 0.737 NM_005244
NM_172110
EYA2

eyes absent homolog 2 (Drosophila)

chr10_-_99161013 0.737 NM_001145114
NM_015179
RRP12

ribosomal RNA processing 12 homolog (S. cerevisiae)

chr17_+_29421956 0.736 NF1
neurofibromin 1
chr7_-_107880492 0.729 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr6_+_31543340 0.729 NM_000594
TNF
tumor necrosis factor
chr17_-_56032494 0.727 CUEDC1
CUE domain containing 1
chr1_+_11796177 0.726 AGTRAP
angiotensin II receptor-associated protein
chr16_+_30675777 0.723 NM_001105079
FBRS
fibrosin
chr17_+_25958192 0.722 LGALS9
lectin, galactoside-binding, soluble, 9
chr2_-_174828775 0.719 NM_001017371
SP3
Sp3 transcription factor
chr6_-_31324564 0.719 HLA-B
HLA-C
major histocompatibility complex, class I, B
major histocompatibility complex, class I, C
chr1_+_11796211 0.717 AGTRAP
angiotensin II receptor-associated protein
chr1_-_27481400 0.717 NM_003047
SLC9A1
solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr6_+_43738757 0.714 VEGFA
vascular endothelial growth factor A
chr3_+_9691198 0.711 MTMR14
myotubularin related protein 14
chr6_-_30654406 0.708 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr3_+_9691184 0.705 MTMR14
myotubularin related protein 14
chr17_+_25958151 0.704 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr6_-_33281847 0.703 TAPBP
TAP binding protein (tapasin)
chr17_-_62657997 0.703 SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr11_-_6502524 0.703 ARFIP2
ADP-ribosylation factor interacting protein 2
chr17_+_5389715 0.701 MIS12
MIS12, MIND kinetochore complex component, homolog (S. pombe)
chr11_+_20070609 0.695 NAV2
neuron navigator 2
chr1_-_33338081 0.694 NM_001171941
FNDC5
fibronectin type III domain containing 5
chr3_+_9691116 0.693 NM_001077525
NM_001077526
NM_022485
MTMR14


myotubularin related protein 14


chr17_+_27717942 0.691 NM_020791
NM_025142
TAOK1

TAO kinase 1

chr17_-_7518124 0.689 NM_004860
FXR2
fragile X mental retardation, autosomal homolog 2
chr4_-_37687932 0.683 NM_001085399
NM_001085400
RELL1

RELT-like 1

chr7_+_151038878 0.679 NUB1
negative regulator of ubiquitin-like proteins 1
chr6_-_33282006 0.677 NM_003190
NM_172208
NM_172209
TAPBP


TAP binding protein (tapasin)


chr18_+_32621299 0.676 NM_014268
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr10_-_27149892 0.673 ABI1
abl-interactor 1
chr10_-_119301750 0.671 EMX2OS
EMX2 opposite strand/antisense RNA (non-protein coding)
chr1_-_167906277 0.670 NM_001143674
NM_015415
BRP44

brain protein 44

chr17_-_46703613 0.669 NM_024017
HOXB9
homeobox B9
chr2_-_60780767 0.669 BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chrX_-_40594663 0.666 MED14
mediator complex subunit 14
chr10_-_75335415 0.661 NM_152586
USP54
ubiquitin specific peptidase 54

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.10 2.67e-22 GO:0009987 cellular process
1.14 9.49e-18 GO:0050789 regulation of biological process
1.13 1.83e-17 GO:0065007 biological regulation
1.15 3.71e-17 GO:0050794 regulation of cellular process
1.25 1.92e-11 GO:0048519 negative regulation of biological process
1.17 2.81e-10 GO:0051716 cellular response to stimulus
1.22 1.30e-09 GO:0048518 positive regulation of biological process
1.24 1.08e-08 GO:0048523 negative regulation of cellular process
1.22 1.65e-08 GO:0048522 positive regulation of cellular process
1.15 2.06e-08 GO:0044260 cellular macromolecule metabolic process
1.18 2.12e-08 GO:0007165 signal transduction
1.17 2.54e-08 GO:0023052 signaling
1.16 6.76e-07 GO:0031323 regulation of cellular metabolic process
1.25 9.51e-07 GO:0023051 regulation of signaling
1.16 1.08e-06 GO:0071840 cellular component organization or biogenesis
1.13 1.15e-06 GO:0043170 macromolecule metabolic process
1.22 1.25e-06 GO:0030154 cell differentiation
1.21 1.53e-06 GO:0048869 cellular developmental process
1.18 1.54e-06 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15 2.06e-06 GO:0019222 regulation of metabolic process
1.23 2.20e-06 GO:0048583 regulation of response to stimulus
1.16 2.66e-06 GO:0080090 regulation of primary metabolic process
1.26 2.89e-06 GO:0009966 regulation of signal transduction
1.16 2.93e-06 GO:0016043 cellular component organization
1.22 1.58e-05 GO:0016070 RNA metabolic process
1.17 1.74e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.30 2.25e-05 GO:0009605 response to external stimulus
1.24 2.88e-05 GO:0007399 nervous system development
1.15 3.45e-05 GO:0060255 regulation of macromolecule metabolic process
1.17 3.54e-05 GO:0071842 cellular component organization at cellular level
1.19 3.59e-05 GO:0090304 nucleic acid metabolic process
1.21 4.62e-05 GO:0010467 gene expression
1.27 4.75e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.25 8.80e-05 GO:0051239 regulation of multicellular organismal process
1.26 1.03e-04 GO:0031325 positive regulation of cellular metabolic process
1.30 1.40e-04 GO:0048468 cell development
1.25 1.45e-04 GO:0009893 positive regulation of metabolic process
1.30 1.47e-04 GO:0006351 transcription, DNA-dependent
1.40 1.77e-04 GO:0006935 chemotaxis
1.40 1.77e-04 GO:0042330 taxis
1.30 2.50e-04 GO:0040011 locomotion
1.30 2.74e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.30 3.26e-04 GO:0009891 positive regulation of biosynthetic process
1.13 3.41e-04 GO:0032502 developmental process
1.30 3.49e-04 GO:0044093 positive regulation of molecular function
1.14 5.41e-04 GO:0048856 anatomical structure development
1.13 6.17e-04 GO:0007275 multicellular organismal development
1.17 7.82e-04 GO:0042221 response to chemical stimulus
1.15 8.46e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.20 1.28e-03 GO:0006996 organelle organization
1.19 1.44e-03 GO:0007166 cell surface receptor linked signaling pathway
1.15 1.72e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15 1.72e-03 GO:0031326 regulation of cellular biosynthetic process
1.15 1.96e-03 GO:0009889 regulation of biosynthetic process
1.27 2.02e-03 GO:0022008 neurogenesis
1.25 2.57e-03 GO:0010646 regulation of cell communication
1.30 2.79e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.45 2.92e-03 GO:0007411 axon guidance
1.21 3.05e-03 GO:0065009 regulation of molecular function
1.28 3.11e-03 GO:0048584 positive regulation of response to stimulus
1.33 3.86e-03 GO:0048666 neuron development
1.15 5.38e-03 GO:0010468 regulation of gene expression
1.21 5.75e-03 GO:0035556 intracellular signal transduction
1.14 6.01e-03 GO:0048731 system development
1.81 6.09e-03 GO:0050851 antigen receptor-mediated signaling pathway
1.35 6.75e-03 GO:0000904 cell morphogenesis involved in differentiation
1.38 7.70e-03 GO:0007409 axonogenesis
1.15 8.00e-03 GO:0006950 response to stress
1.23 8.01e-03 GO:0051246 regulation of protein metabolic process
1.31 8.62e-03 GO:0032989 cellular component morphogenesis
1.25 9.05e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.45 9.14e-03 GO:0051130 positive regulation of cellular component organization
1.29 1.01e-02 GO:0030182 neuron differentiation
1.19 1.04e-02 GO:0009653 anatomical structure morphogenesis
1.24 1.08e-02 GO:0032268 regulation of cellular protein metabolic process
1.36 1.22e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.26 1.48e-02 GO:0048699 generation of neurons
1.36 1.52e-02 GO:0048812 neuron projection morphogenesis
1.28 1.53e-02 GO:0043085 positive regulation of catalytic activity
1.24 1.58e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.29 1.92e-02 GO:0010628 positive regulation of gene expression
1.12 1.92e-02 GO:0034641 cellular nitrogen compound metabolic process
1.35 2.14e-02 GO:0002684 positive regulation of immune system process
1.33 2.40e-02 GO:0001775 cell activation
1.23 2.47e-02 GO:0009892 negative regulation of metabolic process
1.23 2.48e-02 GO:0032879 regulation of localization
1.28 2.84e-02 GO:0051254 positive regulation of RNA metabolic process
1.08 2.85e-02 GO:0050896 response to stimulus
1.12 3.04e-02 GO:0006807 nitrogen compound metabolic process
1.30 3.27e-02 GO:0000902 cell morphogenesis
1.14 3.28e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.25 4.46e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.53 4.50e-02 GO:0002757 immune response-activating signal transduction

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 6.15e-17 GO:0005634 nucleus
1.28 1.77e-14 GO:0044428 nuclear part
1.08 1.30e-13 GO:0044424 intracellular part
1.30 1.76e-13 GO:0031981 nuclear lumen
1.07 1.02e-12 GO:0005622 intracellular
1.22 2.57e-09 GO:0043233 organelle lumen
1.22 2.94e-09 GO:0031974 membrane-enclosed lumen
1.22 5.72e-09 GO:0070013 intracellular organelle lumen
1.08 8.42e-09 GO:0043227 membrane-bounded organelle
1.07 1.36e-08 GO:0043226 organelle
1.08 1.80e-08 GO:0043231 intracellular membrane-bounded organelle
1.07 3.60e-08 GO:0043229 intracellular organelle
1.26 6.16e-07 GO:0005654 nucleoplasm
1.17 9.05e-07 GO:0043234 protein complex
1.08 1.54e-06 GO:0005737 cytoplasm
1.14 3.22e-06 GO:0032991 macromolecular complex
1.10 6.81e-06 GO:0044422 organelle part
1.10 1.27e-05 GO:0044446 intracellular organelle part
1.32 4.75e-05 GO:0044451 nucleoplasm part
1.03 2.91e-04 GO:0044464 cell part
1.03 3.13e-04 GO:0005623 cell
1.36 3.15e-04 GO:0005730 nucleolus
1.16 3.81e-04 GO:0044459 plasma membrane part
1.14 8.31e-04 GO:0043228 non-membrane-bounded organelle
1.14 8.31e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.15 5.79e-03 GO:0005829 cytosol
1.35 5.87e-03 GO:0043005 neuron projection
1.50 8.02e-03 GO:0030425 dendrite
1.29 1.05e-02 GO:0005694 chromosome
1.19 1.43e-02 GO:0031226 intrinsic to plasma membrane
1.22 1.48e-02 GO:0042995 cell projection
1.18 1.83e-02 GO:0005887 integral to plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.19 2.28e-33 GO:0005515 protein binding
1.08 2.18e-19 GO:0005488 binding
1.36 7.16e-10 GO:0030528 transcription regulator activity
1.36 5.08e-06 GO:0043565 sequence-specific DNA binding
1.51 2.19e-05 GO:0016563 transcription activator activity
1.51 2.26e-05 GO:0016564 transcription repressor activity
1.25 7.98e-04 GO:0001071 nucleic acid binding transcription factor activity
1.25 7.98e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.47 1.80e-03 GO:0032403 protein complex binding
1.27 3.95e-03 GO:0019899 enzyme binding
1.15 4.34e-03 GO:0000166 nucleotide binding
1.50 8.57e-03 GO:0000975 regulatory region DNA binding
1.50 8.57e-03 GO:0001067 regulatory region nucleic acid binding
1.50 8.57e-03 GO:0044212 transcription regulatory region DNA binding
1.49 1.73e-02 GO:0010843 promoter binding
1.11 2.93e-02 GO:0003676 nucleic acid binding