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Motif ID: SPZ1.p2

Z-value: 1.774

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr13_-_72441312	8.395	NM_004392 NM_080759 NM_080760	DACH1	dachshund homolog 1 (Drosophila)
chr13_-_72440557	7.149		DACH1	dachshund homolog 1 (Drosophila)
chr13_-_72440143	5.793		DACH1	dachshund homolog 1 (Drosophila)
chr3_+_8543508	5.596	NM_014583	LMCD1	LIM and cysteine-rich domains 1
chr5_+_137801178	4.034	NM_001964	EGR1	early growth response 1
chr14_+_24867926	3.973	NM_025081	NYNRIN	NYN domain and retroviral integrase containing
chr19_-_17356022	3.566	NM_005234	NR2F6	nuclear receptor subfamily 2, group F, member 6
chr3_-_18466759	3.317	NM_001195470 NM_002971	SATB1	SATB homeobox 1
chr3_-_182833859	2.914		MCCC1	methylcrotonoyl-CoA carboxylase 1 (alpha)
chr12_+_53440809	2.899	NM_198316	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr3_+_20081523	2.851	NM_003884	KAT2B	K(lysine) acetyltransferase 2B
chr3_+_110790460	2.572	NM_001243286 NM_015480	PVRL3	poliovirus receptor-related 3
chrX_-_62570968	2.546	NM_001012968	SPIN4	spindlin family, member 4
chr3_+_20081853	2.489		KAT2B	K(lysine) acetyltransferase 2B
chr2_-_217236666	2.422	NM_020814	MARCH4	membrane-associated ring finger (C3HC4) 4
chr1_+_221052845	2.405		HLX	H2.0-like homeobox
chr11_-_67888857	2.399	NM_001277 NM_212469	CHKA	choline kinase alpha
chr14_-_91526912	2.388	NM_004755 NM_182398	RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr3_+_37903643	2.378	NM_001008392 NM_005808	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr1_+_164528586	2.288	NM_001204961 NM_001204963 NM_002585	PBX1	pre-B-cell leukemia homeobox 1
chr1_+_78444922	2.274		DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr6_-_119670897	2.255	NM_005907	MAN1A1	mannosidase, alpha, class 1A, member 1
chr6_-_84418705	2.248	NM_001242792	SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)
chr12_-_76425207	2.230		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr9_-_80646150	2.156	NM_002072	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide
chr2_-_220436010	2.151		OBSL1	obscurin-like 1
chr21_+_46020496	2.125	NM_198689	KRTAP10-7	keratin associated protein 10-7
chr15_-_23378217	2.098		HERC2P2	hect domain and RLD 2 pseudogene 2
chr12_+_79258448	2.035	NM_005639	SYT1	synaptotagmin I
chr14_+_61788398	2.024	NM_006255	PRKCH	protein kinase C, eta
chr21_+_45993605	2.023	NM_198687	KRTAP10-4	keratin associated protein 10-4
chr11_-_67888670	1.960		CHKA	choline kinase alpha
chr12_+_79258588	1.933		SYT1	synaptotagmin I
chr2_-_165477986	1.881		GRB14	growth factor receptor-bound protein 14
chr9_-_94124194	1.852	NM_001698	AUH	AU RNA binding protein/enoyl-CoA hydratase
chr2_-_152684933	1.819		ARL5A	ADP-ribosylation factor-like 5A
chr2_-_136288768	1.808	NM_032143	ZRANB3	zinc finger, RAN-binding domain containing 3
chr2_-_152684882	1.806		ARL5A	ADP-ribosylation factor-like 5A
chr2_-_152684963	1.781	NM_001037174 NM_012097 NM_177985	ARL5A	ADP-ribosylation factor-like 5A
chr3_+_193853937	1.779		HES1	hairy and enhancer of split 1, (Drosophila)
chr2_-_152684689	1.767		ARL5A	ADP-ribosylation factor-like 5A
chr2_-_165477818	1.754		GRB14	growth factor receptor-bound protein 14
chr12_+_53443834	1.726	NM_170754	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr3_+_8543539	1.719		LMCD1	LIM and cysteine-rich domains 1
chrX_+_118108595	1.716	NM_001031855 NM_024778	LONRF3	LON peptidase N-terminal domain and ring finger 3
chr9_+_22447064	1.712
chr6_-_111894897	1.710	NM_001164282	TRAF3IP2	TRAF3 interacting protein 2
chr12_+_79258517	1.701		SYT1	synaptotagmin I
chr12_-_46766563	1.695	NM_018976	SLC38A2	solute carrier family 38, member 2
chr8_-_22550057	1.676	NM_001199881	EGR3	early growth response 3
chr1_+_212459169	1.672		PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha
chr20_+_33759773	1.650	NM_006404	PROCR	protein C receptor, endothelial
chr1_+_25943958	1.638	NM_020379	MAN1C1	mannosidase, alpha, class 1C, member 1
chr3_+_193853930	1.620	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr7_+_73442468	1.616		ELN	elastin
chr13_-_49107185	1.613		RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr9_-_94124149	1.586		AUH	AU RNA binding protein/enoyl-CoA hydratase
chr6_-_13486986	1.586		GFOD1	glucose-fructose oxidoreductase domain containing 1
chr20_+_34742656	1.581	NM_012156	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chrX_+_118108575	1.573		LONRF3	LON peptidase N-terminal domain and ring finger 3
chr10_+_8096633	1.569	NM_001002295 NM_002051	GATA3	GATA binding protein 3
chr6_-_110500803	1.561		WASF1	WAS protein family, member 1
chr19_+_17581276	1.547	NM_198580	SLC27A1	solute carrier family 27 (fatty acid transporter), member 1
chr2_+_46524448	1.496	NM_001430	EPAS1	endothelial PAS domain protein 1
chr10_+_35416089	1.485		CREM	cAMP responsive element modulator
chr8_-_125384916	1.479	NM_194291	TMEM65	transmembrane protein 65
chr6_-_32163890	1.459		NOTCH4	notch 4
chr17_+_38599651	1.432	NM_001552	IGFBP4	insulin-like growth factor binding protein 4
chr7_-_21985421	1.423	NM_001127370 NM_001127371 NM_018719	CDCA7L	cell division cycle associated 7-like
chr6_-_70506843	1.418	NM_018368	LMBRD1	LMBR1 domain containing 1
chr8_-_74659082	1.413	NM_001164380 NM_001164381 NM_001164382 NM_001164383 NM_001164385 NM_014393	STAU2	staufen, RNA binding protein, homolog 2 (Drosophila)
chr8_-_93107442	1.410	NM_001198629 NM_001198630 NM_001198632 NM_175635	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_+_74493893	1.396	NM_145052	UPRT	uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr2_+_33172368	1.376	NM_206943	LTBP1	latent transforming growth factor beta binding protein 1
chr10_+_8096772	1.364		GATA3	GATA binding protein 3
chr6_-_70506768	1.359		LMBRD1	LMBR1 domain containing 1
chr2_+_159313407	1.356		PKP4	plakophilin 4
chr5_+_137801166	1.352		EGR1	early growth response 1
chr1_-_33647626	1.334	NM_018207	TRIM62	tripartite motif containing 62
chr17_-_47841517	1.322	NM_030802	FAM117A	family with sequence similarity 117, member A
chr17_-_47841468	1.318		FAM117A	family with sequence similarity 117, member A
chr15_-_23378167	1.314		HERC2P2	hect domain and RLD 2 pseudogene 2
chr1_+_77747727	1.310		AK5	adenylate kinase 5
chr13_+_37393306	1.306	NM_000538	RFXAP	regulatory factor X-associated protein
chr2_+_113403433	1.299	NM_005415	SLC20A1	solute carrier family 20 (phosphate transporter), member 1
chr6_-_52441714	1.297		TRAM2	translocation associated membrane protein 2
chr2_+_46524901	1.294		EPAS1	endothelial PAS domain protein 1
chr6_-_70506524	1.277		LMBRD1	LMBR1 domain containing 1
chr1_+_90098693	1.272		LRRC8C	leucine rich repeat containing 8 family, member C
chr18_-_72920989	1.264
chr6_+_122720685	1.263	NM_001135564 NM_001243094 NM_004506	HSF2	heat shock transcription factor 2
chr16_+_30960377	1.260	NM_152288	ORAI3	ORAI calcium release-activated calcium modulator 3
chr11_+_59522905	1.255		STX3	syntaxin 3
chr13_+_103451398	1.254	NM_001159596 NM_017693	BIVM	basic, immunoglobulin-like variable motif containing
chr6_-_84937313	1.253	NM_014895	KIAA1009	KIAA1009
chr13_+_42031525	1.242	NM_014059	C13orf15	chromosome 13 open reading frame 15
chr1_+_221052735	1.240	NM_021958	HLX	H2.0-like homeobox
chr1_+_210406194	1.226	NM_019605	SERTAD4	SERTA domain containing 4
chr17_+_68165660	1.225	NM_000891	KCNJ2	potassium inwardly-rectifying channel, subfamily J, member 2
chr2_-_43453146	1.220		ZFP36L2	zinc finger protein 36, C3H type-like 2
chr12_-_46766019	1.218		SLC38A2	solute carrier family 38, member 2
chr21_-_44846927	1.218	NM_173354	SIK1	salt-inducible kinase 1
chr1_+_77747602	1.210	NM_174858	AK5	adenylate kinase 5
chr2_-_39664430	1.195		MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3
chr16_+_68119211	1.189	NM_004555 NM_173163 NM_173165	NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr9_-_14313509	1.186		NFIB	nuclear factor I/B
chr11_-_57283145	1.180	NM_003627	SLC43A1	solute carrier family 43, member 1
chr14_-_23588819	1.176	NM_001805	CEBPE	CCAAT/enhancer binding protein (C/EBP), epsilon
chr7_+_77428204	1.171		PHTF2	putative homeodomain transcription factor 2
chr6_+_107811272	1.170	NM_018013	SOBP	sine oculis binding protein homolog (Drosophila)
chr1_-_9970265	1.165	NM_001012329 NM_020248	CTNNBIP1	catenin, beta interacting protein 1
chr5_-_112824526	1.159	NM_001085377	MCC	mutated in colorectal cancers
chr17_-_36956145	1.154	NM_003559	PIP4K2B	phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr17_+_7812703	1.141		CHD3	chromodomain helicase DNA binding protein 3
chr19_+_35760002	1.136		USF2	upstream transcription factor 2, c-fos interacting
chr9_+_6215785	1.131	NM_001199640 NM_001199641 NM_033439	IL33	interleukin 33
chr2_+_159313466	1.128	NM_001005476 NM_003628	PKP4	plakophilin 4
chr1_+_109102970	1.118	NM_001010883	FAM102B	family with sequence similarity 102, member B
chr10_-_105452878	1.117		SH3PXD2A	SH3 and PX domains 2A
chr8_-_17658385	1.117	NM_001001924 NM_001001925	MTUS1	microtubule associated tumor suppressor 1
chr2_-_165478357	1.108	NM_004490	GRB14	growth factor receptor-bound protein 14
chr17_-_16118789	1.108	NM_006311	NCOR1	nuclear receptor corepressor 1
chr8_+_144816287	1.105		LOC100128338	uncharacterized LOC100128338
chr17_-_48943672	1.103	NM_001243885 NM_005749	TOB1	transducer of ERBB2, 1
chr1_+_153700540	1.090	NM_023015	INTS3	integrator complex subunit 3
chr17_+_47866061	1.088		KAT7	K(lysine) acetyltransferase 7
chr3_+_25469833	1.083	NM_000965	RARB	retinoic acid receptor, beta
chr8_-_9008138	1.079	NM_024607	PPP1R3B	protein phosphatase 1, regulatory subunit 3B
chr2_+_177134122	1.068	NM_006554	MTX2	metaxin 2
chr8_-_22550708	1.063	NM_004430	EGR3	early growth response 3
chr13_+_35516390	1.057	NM_015678	NBEA	neurobeachin
chr1_+_26146446	1.049		FAM54B	family with sequence similarity 54, member B
chr6_+_148663728	1.046	NM_015278	SASH1	SAM and SH3 domain containing 1
chr4_+_113066552	1.045	NM_152400	C4orf32	chromosome 4 open reading frame 32
chr12_-_42983412	1.044	NM_153026	PRICKLE1	prickle homolog 1 (Drosophila)
chr1_+_16083132	1.040		FBLIM1	filamin binding LIM protein 1
chr12_-_31743822	1.034	NM_144973	DENND5B	DENN/MADD domain containing 5B
chr1_+_65886315	1.025	NM_001003679 NM_001003680 NM_002303 NM_001198681	LEPR LEPROT	leptin receptor leptin receptor overlapping transcript
chr14_+_65879694	1.024		FUT8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr1_+_179851968	1.022		TOR1AIP1	torsin A interacting protein 1
chr14_-_23285011	1.021	NM_001126105	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chrX_+_107069502	1.018		MID2	midline 2
chr1_+_212459262	1.018		PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha
chr19_-_14201230	1.016	NM_138352	SAMD1	sterile alpha motif domain containing 1
chr12_-_56727446	1.015	NM_001127460	PAN2	PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr12_-_12503135	1.015	NM_018050	MANSC1	MANSC domain containing 1
chr1_+_92495484	1.014	NM_173567	EPHX4	epoxide hydrolase 4
chr13_+_42031690	1.008		C13orf15	chromosome 13 open reading frame 15
chr21_+_27107731	0.998		GABPA	GA binding protein transcription factor, alpha subunit 60kDa
chr19_+_32897021	0.996	NM_207325	DPY19L3	dpy-19-like 3 (C. elegans)
chr3_-_93692592	0.996		PROS1	protein S (alpha)
chr12_-_109125254	0.992		CORO1C	coronin, actin binding protein, 1C
chr8_-_93115453	0.992	NM_001198633 NM_175634	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_25870043	0.989	NM_015627	LDLRAP1	low density lipoprotein receptor adaptor protein 1
chr6_+_30851860	0.982	NM_001954	DDR1	discoidin domain receptor tyrosine kinase 1
chrX_-_62974341	0.975		ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr14_-_90085325	0.969	NM_001085471	FOXN3	forkhead box N3
chr11_-_118135197	0.968	NM_005797 NM_144765	MPZL2	myelin protein zero-like 2
chr13_-_49107250	0.962	NM_001268	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr1_+_65991390	0.957		LEPR	leptin receptor
chr11_-_118134986	0.955		MPZL2	myelin protein zero-like 2
chr1_+_65720091	0.949		LOC645195 DNAJC6	uncharacterized LOC645195 DnaJ (Hsp40) homolog, subfamily C, member 6
chr1_+_25870143	0.947		LDLRAP1	low density lipoprotein receptor adaptor protein 1
chrX_-_70473941	0.943		ZMYM3	zinc finger, MYM-type 3
chr20_+_21106718	0.940		PLK1S1	polo-like kinase 1 substrate 1
chr8_-_17555158	0.938	NM_020749	MTUS1	microtubule associated tumor suppressor 1
chr6_-_52441815	0.930	NM_012288	TRAM2	translocation associated membrane protein 2
chr6_+_15245702	0.926		JARID2	jumonji, AT rich interactive domain 2
chr4_-_146859960	0.926
chr19_+_1248548	0.919	NM_177401	MIDN	midnolin
chr1_-_6296034	0.918	NM_012405	ICMT	isoprenylcysteine carboxyl methyltransferase
chr6_+_31674639	0.914	NM_001003693	LY6G6F	lymphocyte antigen 6 complex, locus G6F
chr3_-_101231973	0.900	NM_001077203 NM_020654	SENP7	SUMO1/sentrin specific peptidase 7
chr6_-_16761600	0.889	NM_000332 NM_001128164	ATXN1	ataxin 1
chr1_+_156863522	0.888	NM_001080471	PEAR1	platelet endothelial aggregation receptor 1
chr19_+_32896515	0.888	NM_001172774	DPY19L3	dpy-19-like 3 (C. elegans)
chrX_-_70473979	0.885	NM_201599	ZMYM3	zinc finger, MYM-type 3
chr13_-_76055872	0.885	NM_014832	TBC1D4	TBC1 domain family, member 4
chr9_-_100459556	0.882		XPA	xeroderma pigmentosum, complementation group A
chr12_-_29936685	0.882	NM_001193451	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr9_-_135230358	0.881	NM_015046	SETX	senataxin
chr1_+_231114839	0.880
chr12_+_48357358	0.880		TMEM106C	transmembrane protein 106C
chrX_-_54521866	0.879		FGD1	FYVE, RhoGEF and PH domain containing 1
chr18_+_21269404	0.875		LAMA3	laminin, alpha 3
chr5_-_63257545	0.871	NM_000524	HTR1A	5-hydroxytryptamine (serotonin) receptor 1A
chr7_-_120498128	0.865	NM_012338	TSPAN12	tetraspanin 12
chr22_+_51113069	0.862	NM_001080420	SHANK3	SH3 and multiple ankyrin repeat domains 3
chr5_+_159656436	0.854	NM_001445	FABP6	fatty acid binding protein 6, ileal
chr14_-_23821423	0.854	NM_020372	SLC22A17	solute carrier family 22, member 17
chr19_+_45971249	0.852	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr11_+_59522801	0.846		STX3	syntaxin 3
chr6_-_133119625	0.843	NM_052831	C6orf192	chromosome 6 open reading frame 192
chr15_+_96873845	0.841	NM_021005	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr12_+_57482886	0.839		NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)
chr15_-_69113213	0.838		ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr1_+_65991357	0.834	NM_001198687 NM_001198688 NM_001198689	LEPR	leptin receptor
chr2_+_191745791	0.833		GLS	glutaminase
chr14_-_20020271	0.830	NM_001145442	POTEG POTEM	POTE ankyrin domain family, member G POTE ankyrin domain family, member M
chr12_-_80084023	0.830		PAWR	PRKC, apoptosis, WT1, regulator

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.22	3.97e-09	GO:0023052	signaling
1.22	9.91e-08	GO:0007165	signal transduction
1.08	3.48e-07	GO:0009987	cellular process
1.12	6.13e-06	GO:0050794	regulation of cellular process
1.32	7.29e-06	GO:0007399	nervous system development
1.11	1.92e-05	GO:0050789	regulation of biological process
1.48	3.41e-05	GO:0007167	enzyme linked receptor protein signaling pathway
1.54	4.50e-05	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.16	5.75e-05	GO:0051716	cellular response to stimulus
1.24	6.19e-05	GO:0048523	negative regulation of cellular process
1.10	8.41e-05	GO:0065007	biological regulation
1.35	5.44e-04	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.20	6.66e-04	GO:0048518	positive regulation of biological process
1.37	6.86e-04	GO:0048699	generation of neurons
1.17	7.09e-04	GO:0007275	multicellular organismal development
1.19	7.60e-04	GO:0048731	system development
1.36	7.88e-04	GO:0022008	neurogenesis
1.26	1.03e-03	GO:0023051	regulation of signaling
1.20	1.76e-03	GO:0048519	negative regulation of biological process
1.27	2.18e-03	GO:0009966	regulation of signal transduction
1.15	2.25e-03	GO:0032502	developmental process
1.20	2.41e-03	GO:0048522	positive regulation of cellular process
1.23	4.87e-03	GO:0007166	cell surface receptor linked signaling pathway
1.22	6.49e-03	GO:0048583	regulation of response to stimulus
1.22	1.20e-02	GO:0006464	protein modification process
1.20	1.28e-02	GO:0030154	cell differentiation
1.65	1.51e-02	GO:0048011	nerve growth factor receptor signaling pathway
1.16	1.76e-02	GO:0048856	anatomical structure development
1.45	3.07e-02	GO:0032583	regulation of gene-specific transcription
1.24	3.15e-02	GO:0035556	intracellular signal transduction
1.23	3.58e-02	GO:0009653	anatomical structure morphogenesis
1.19	4.20e-02	GO:0048869	cellular developmental process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.12	3.35e-10	GO:0005737	cytoplasm
1.07	1.79e-08	GO:0005622	intracellular
1.08	2.13e-08	GO:0044424	intracellular part
1.07	7.35e-05	GO:0043229	intracellular organelle
1.07	9.56e-05	GO:0043226	organelle
1.85	1.07e-04	GO:0070161	anchoring junction
1.44	1.20e-04	GO:0030054	cell junction
1.85	3.76e-04	GO:0005912	adherens junction
1.07	7.70e-03	GO:0043231	intracellular membrane-bounded organelle
1.07	8.91e-03	GO:0043227	membrane-bounded organelle
1.86	1.46e-02	GO:0005924	cell-substrate adherens junction
1.03	1.58e-02	GO:0044464	cell part
1.03	1.66e-02	GO:0005623	cell
1.84	1.67e-02	GO:0030055	cell-substrate junction
1.09	2.13e-02	GO:0044444	cytoplasmic part
1.86	2.43e-02	GO:0005925	focal adhesion
1.54	2.64e-02	GO:0016323	basolateral plasma membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.15	1.16e-13	GO:0005515	protein binding
1.07	7.63e-07	GO:0005488	binding
1.47	6.96e-03	GO:0000988	protein binding transcription factor activity
1.47	6.96e-03	GO:0000989	transcription factor binding transcription factor activity
1.29	7.07e-03	GO:0030234	enzyme regulator activity
1.46	1.04e-02	GO:0003712	transcription cofactor activity
1.32	1.34e-02	GO:0019899	enzyme binding
2.24	2.37e-02	GO:0004879	ligand-dependent nuclear receptor activity
1.36	2.91e-02	GO:0008092	cytoskeletal protein binding
1.40	3.91e-02	GO:0019904	protein domain specific binding