Motif ID: SPZ1.p2

Z-value: 1.774


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
SPZ1 84654 spermatogenic leucine zipper 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
SPZ1chr5_+_79615789-0.029.2e-01Click!


Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_72441312 8.395 NM_004392
NM_080759
NM_080760
 DACH1


dachshund homolog 1 (Drosophila)


chr13_-_72440557 7.149 DACH1
dachshund homolog 1 (Drosophila)
chr13_-_72440143 5.793 DACH1
dachshund homolog 1 (Drosophila)
chr3_+_8543508 5.596 NM_014583
 LMCD1
LIM and cysteine-rich domains 1
chr5_+_137801178 4.034 NM_001964
 EGR1
early growth response 1
chr14_+_24867926 3.973 NM_025081
 NYNRIN
NYN domain and retroviral integrase containing
chr19_-_17356022 3.566 NM_005234
 NR2F6
nuclear receptor subfamily 2, group F, member 6
chr3_-_18466759 3.317 NM_001195470
NM_002971
 SATB1

SATB homeobox 1

chr3_-_182833859 2.914 MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr12_+_53440809 2.899 NM_198316
 TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_+_20081523 2.851 NM_003884
 KAT2B
K(lysine) acetyltransferase 2B
chr3_+_110790460 2.572 NM_001243286
NM_015480
 PVRL3

poliovirus receptor-related 3

chrX_-_62570968 2.546 NM_001012968
 SPIN4
spindlin family, member 4
chr3_+_20081853 2.489 KAT2B
K(lysine) acetyltransferase 2B
chr2_-_217236666 2.422 NM_020814
 MARCH4
membrane-associated ring finger (C3HC4) 4
chr1_+_221052845 2.405 HLX
H2.0-like homeobox
chr11_-_67888857 2.399 NM_001277
NM_212469
 CHKA

choline kinase alpha

chr14_-_91526912 2.388 NM_004755
NM_182398
 RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr3_+_37903643 2.378 NM_001008392
NM_005808
 CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr1_+_164528586 2.288 NM_001204961
NM_001204963
NM_002585
 PBX1


pre-B-cell leukemia homeobox 1



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
1.65 1.51e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.54 4.50e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.48 3.41e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.45 3.07e-02 GO:0032583 regulation of gene-specific transcription
1.37 6.86e-04 GO:0048699 generation of neurons
1.36 7.88e-04 GO:0022008 neurogenesis
1.35 5.44e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.32 7.29e-06 GO:0007399 nervous system development
1.27 2.18e-03 GO:0009966 regulation of signal transduction
1.26 1.03e-03 GO:0023051 regulation of signaling
1.24 6.19e-05 GO:0048523 negative regulation of cellular process
1.24 3.15e-02 GO:0035556 intracellular signal transduction
1.23 4.87e-03 GO:0007166 cell surface receptor linked signaling pathway
1.23 3.58e-02 GO:0009653 anatomical structure morphogenesis
1.22 3.97e-09 GO:0023052 signaling
1.22 9.91e-08 GO:0007165 signal transduction
1.22 6.49e-03 GO:0048583 regulation of response to stimulus
1.22 1.20e-02 GO:0006464 protein modification process
1.20 6.66e-04 GO:0048518 positive regulation of biological process
1.20 1.76e-03 GO:0048519 negative regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
1.86 1.46e-02 GO:0005924 cell-substrate adherens junction
1.86 2.43e-02 GO:0005925 focal adhesion
1.85 1.07e-04 GO:0070161 anchoring junction
1.85 3.76e-04 GO:0005912 adherens junction
1.84 1.67e-02 GO:0030055 cell-substrate junction
1.54 2.64e-02 GO:0016323 basolateral plasma membrane
1.44 1.20e-04 GO:0030054 cell junction
1.12 3.35e-10 GO:0005737 cytoplasm
1.09 2.13e-02 GO:0044444 cytoplasmic part
1.08 2.13e-08 GO:0044424 intracellular part
1.07 1.79e-08 GO:0005622 intracellular
1.07 7.35e-05 GO:0043229 intracellular organelle
1.07 9.56e-05 GO:0043226 organelle
1.07 7.70e-03 GO:0043231 intracellular membrane-bounded organelle
1.07 8.91e-03 GO:0043227 membrane-bounded organelle
1.03 1.58e-02 GO:0044464 cell part
1.03 1.66e-02 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
2.24 2.37e-02 GO:0004879 ligand-dependent nuclear receptor activity
1.47 6.96e-03 GO:0000988 protein binding transcription factor activity
1.47 6.96e-03 GO:0000989 transcription factor binding transcription factor activity
1.46 1.04e-02 GO:0003712 transcription cofactor activity
1.40 3.91e-02 GO:0019904 protein domain specific binding
1.36 2.91e-02 GO:0008092 cytoskeletal protein binding
1.32 1.34e-02 GO:0019899 enzyme binding
1.29 7.07e-03 GO:0030234 enzyme regulator activity
1.15 1.16e-13 GO:0005515 protein binding
1.07 7.63e-07 GO:0005488 binding