Motif ID: SRF.p3

Z-value: 1.511


Transcription factors associated with SRF.p3:

Gene SymbolEntrez IDGene Name
SRF 6722 serum response factor (c-fos serum response element-binding transcription factor)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
SRFchr6_+_431391900.116.0e-01Click!


Activity profile for motif SRF.p3.

activity profile for motif SRF.p3


Sorted Z-values histogram for motif SRF.p3

Sorted Z-values for motif SRF.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of SRF.p3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_137801166 38.093 EGR1
early growth response 1
chr5_+_137801178 23.711 NM_001964
 EGR1
early growth response 1
chr10_-_64576123 11.434 NM_000399
NM_001136177
NM_001136179
 EGR2


early growth response 2


chr10_-_64576074 10.962 EGR2
early growth response 2
chr8_-_22550708 4.710 NM_004430
 EGR3
early growth response 3
chr19_+_45971249 4.533 NM_001114171
NM_006732
 FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr10_+_112257624 3.811 NM_004419
 DUSP5
dual specificity phosphatase 5
chr12_+_52445185 2.593 NM_002135
NM_173157
 NR4A1

nuclear receptor subfamily 4, group A, member 1

chr20_+_35169876 2.503 NM_006097
NM_181526
 MYL9

myosin, light chain 9, regulatory

chr14_+_75745480 2.247 NM_005252
 FOS
FBJ murine osteosarcoma viral oncogene homolog
chr20_+_35169897 2.226 MYL9
myosin, light chain 9, regulatory
chr19_+_49376488 2.132 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr11_-_65667809 2.001 FOSL1
FOS-like antigen 1
chr11_-_65667858 1.877 FOSL1
FOS-like antigen 1
chr1_+_181057835 1.874 IER5
immediate early response 5
chr11_-_65667860 1.857 NM_005438
 FOSL1
FOS-like antigen 1
chr2_-_73520448 1.758 NM_001965
 EGR4
early growth response 4
chr4_+_81118639 1.693 NM_001099403
 PRDM8
PR domain containing 8
chr5_-_33892292 1.647 ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr6_-_29527701 1.560 NM_006398
 UBD
ubiquitin D

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
25.25 1.45e-02 GO:0043534 blood vessel endothelial cell migration
17.22 9.06e-03 GO:0043542 endothelial cell migration
13.95 6.14e-04 GO:0070252 actin-mediated cell contraction
13.37 2.12e-05 GO:0030048 actin filament-based movement
12.28 8.83e-03 GO:0030049 muscle filament sliding
12.28 8.83e-03 GO:0033275 actin-myosin filament sliding
6.71 2.56e-05 GO:0006936 muscle contraction
6.61 9.90e-06 GO:0003012 muscle system process
5.35 1.13e-03 GO:0007517 muscle organ development
4.39 2.07e-03 GO:0061061 muscle structure development
4.21 3.45e-03 GO:0030029 actin filament-based process
3.81 4.57e-02 GO:0010035 response to inorganic substance
2.54 1.42e-02 GO:0009888 tissue development
2.11 7.17e-04 GO:0048513 organ development
1.99 2.73e-03 GO:0030154 cell differentiation
1.98 1.61e-06 GO:0048856 anatomical structure development
1.97 2.53e-05 GO:0048731 system development
1.94 1.00e-06 GO:0007275 multicellular organismal development
1.94 5.83e-03 GO:0048869 cellular developmental process
1.90 4.38e-07 GO:0032502 developmental process

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
15.15 4.03e-04 GO:0032432 actin filament bundle
13.53 5.24e-03 GO:0001725 stress fiber
11.48 1.20e-02 GO:0042641 actomyosin
8.05 5.78e-06 GO:0044449 contractile fiber part
8.01 1.62e-06 GO:0043292 contractile fiber
7.84 7.76e-06 GO:0030016 myofibril
6.19 8.28e-03 GO:0030017 sarcomere
6.12 8.91e-03 GO:0005925 focal adhesion
5.83 1.27e-02 GO:0005924 cell-substrate adherens junction
5.61 1.65e-02 GO:0030055 cell-substrate junction
5.04 1.56e-06 GO:0015629 actin cytoskeleton
4.58 2.94e-02 GO:0005912 adherens junction
2.11 9.13e-04 GO:0005856 cytoskeleton
1.79 1.40e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
18.94 9.84e-03 GO:0000146 microfilament motor activity
3.62 4.06e-03 GO:0003779 actin binding
1.38 6.27e-04 GO:0005515 protein binding