Motif ID: SRY.p2

Z-value: 1.361


Transcription factors associated with SRY.p2:

Gene SymbolEntrez IDGene Name
SRY 6736 sex determining region Y

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
SRYchrY_-_2655478-0.116.0e-01Click!


Activity profile for motif SRY.p2.

activity profile for motif SRY.p2


Sorted Z-values histogram for motif SRY.p2

Sorted Z-values for motif SRY.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SRY.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_41614933 10.739 LIMCH1
LIM and calponin homology domains 1
chr4_+_41614725 9.942 LIMCH1
LIM and calponin homology domains 1
chr4_+_41614911 9.504 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr17_-_67138013 6.601 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr4_-_101439071 6.333 NM_001159694
NM_016242
EMCN

endomucin

chr6_-_76203256 5.956 NM_015687
FILIP1
filamin A interacting protein 1
chr1_+_84630575 5.910 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr9_-_107690526 5.856 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr1_+_84768333 5.667 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr1_+_61547388 5.445 NM_001145512
NFIA
nuclear factor I/A
chr10_+_35426709 5.384 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr2_-_225266710 5.245 NM_001122779
NM_024785
FAM124B

family with sequence similarity 124B

chr5_-_111091947 5.195 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr4_-_186732047 4.978 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr3_-_149051258 4.975 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr6_-_130031278 4.624 NM_033515
ARHGAP18
Rho GTPase activating protein 18
chr4_-_16900028 4.448 LDB2
LIM domain binding 2
chr1_+_84609941 4.182 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_186732208 3.980 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr9_-_16727887 3.682 BNC2
basonuclin 2
chr10_-_116444374 3.474 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr7_+_30960914 3.436 NM_001185060
NM_001185061
NM_001185062
AQP1


aquaporin 1 (Colton blood group)


chr9_-_8733893 3.355 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr4_-_186697065 3.349 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr8_-_80993009 3.276 NM_001025252
TPD52
tumor protein D52
chr1_+_84647342 3.195 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr9_-_14314036 2.941 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr12_+_79439432 2.881 NM_001135806
SYT1
synaptotagmin I
chr1_+_84630014 2.710 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chrX_-_117107700 2.630 NM_033495
NM_001168300
KLHL13

kelch-like 13 (Drosophila)

chr1_+_61547625 2.626 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr4_+_41540187 2.596 LIMCH1
LIM and calponin homology domains 1
chr3_+_132316080 2.591 NM_016557
CCRL1
chemokine (C-C motif) receptor-like 1
chr1_+_84767288 2.590 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr5_-_111312522 2.550 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr18_+_72922725 2.543 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr4_-_90759446 2.487 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr10_-_116444112 2.482 ABLIM1
actin binding LIM protein 1
chr3_+_132318980 2.463 NM_178445
CCRL1
chemokine (C-C motif) receptor-like 1
chr14_-_23288912 2.436 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr18_-_53071225 2.413 NM_001243232
TCF4
transcription factor 4
chr4_-_16900256 2.376 LDB2
LIM domain binding 2
chr17_-_8424217 2.369 MYH10
myosin, heavy chain 10, non-muscle
chr12_+_32654976 2.346 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr15_-_59665069 2.305 NM_004998
MYO1E
myosin IE
chr4_-_16900348 2.286 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr12_+_20724797 2.275 NM_001244683
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr18_+_20715726 2.225 NM_001100619
CABLES1
Cdk5 and Abl enzyme substrate 1
chr14_-_92414004 2.224 NM_006329
FBLN5
fibulin 5
chr1_+_66458389 2.176 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr18_-_52988916 2.158 NM_001243234
NM_001243235
TCF4

transcription factor 4

chr4_+_41540320 2.155 LIMCH1
LIM and calponin homology domains 1
chr12_-_9268440 2.143 A2M
alpha-2-macroglobulin
chr12_-_9268513 2.143 A2M
alpha-2-macroglobulin
chr12_-_9268522 2.122 NM_000014
A2M
alpha-2-macroglobulin
chr8_-_93075190 2.120 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_-_99891690 2.113 NM_003270
TSPAN6
tetraspanin 6
chr14_-_92413738 2.104 FBLN5
fibulin 5
chr7_+_80267922 2.096 CD36
CD36 molecule (thrombospondin receptor)
chr7_+_102553343 2.096 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chr7_+_80267782 2.092 NM_000072
NM_001001548
CD36

CD36 molecule (thrombospondin receptor)

chr3_-_165555252 2.020 NM_000055
BCHE
butyrylcholinesterase
chrX_+_28605558 2.019 NM_014271
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr1_+_185703470 1.996 NM_031935
HMCN1
hemicentin 1
chr18_+_42260774 1.987 NM_015559
SETBP1
SET binding protein 1
chr8_-_82395401 1.978 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr13_-_48987017 1.967 LPAR6
lysophosphatidic acid receptor 6
chr13_-_48987247 1.952 LPAR6
lysophosphatidic acid receptor 6
chr18_-_22930826 1.945


chr3_-_165555167 1.930 BCHE
butyrylcholinesterase
chr14_-_89883306 1.928 NM_005197
FOXN3
forkhead box N3
chrX_-_135863033 1.921 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr13_-_48987652 1.868 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr18_-_53177999 1.867 NM_001243231
TCF4
transcription factor 4
chrX_-_135863104 1.864 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chrX_-_135863502 1.830 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr12_-_9268475 1.824 A2M
alpha-2-macroglobulin
chr2_+_12857885 1.807 TRIB2
tribbles homolog 2 (Drosophila)
chr2_-_165424993 1.799 GRB14
growth factor receptor-bound protein 14
chr2_-_188312872 1.799 NM_005795
CALCRL
calcitonin receptor-like
chr2_+_12856813 1.788 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr9_-_14086901 1.780 NFIB
nuclear factor I/B
chr12_+_93963597 1.779 NM_003877
SOCS2
suppressor of cytokine signaling 2
chrX_-_117119282 1.744 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr5_-_88119604 1.733 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr12_-_7848324 1.733 NM_020634
GDF3
growth differentiation factor 3
chr2_+_169923531 1.705 NM_199204
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr2_+_110656008 1.652 NM_001205288
NM_033514
LIMS3-LOC440895
LIMS3L
LIMS3
LIMS3-LOC440895 readthrough
LIM and senescent cell antigen-like domains 3-like
LIM and senescent cell antigen-like domains 3
chr4_+_140587086 1.651 MGST2
microsomal glutathione S-transferase 2
chr12_-_102591547 1.648 NM_002674
PMCH
pro-melanin-concentrating hormone
chr4_+_140586921 1.640 NM_001204366
NM_001204367
NM_001204368
NM_002413
MGST2



microsomal glutathione S-transferase 2



chr2_-_191872322 1.634 STAT1
signal transducer and activator of transcription 1, 91kDa
chr2_-_111230651 1.629 NM_001205288
NM_033514
LIMS3-LOC440895
LIMS3L
LIMS3
LIMS3-LOC440895 readthrough
LIM and senescent cell antigen-like domains 3-like
LIM and senescent cell antigen-like domains 3
chr1_+_43766565 1.628 NM_001253357
NM_005424
TIE1

tyrosine kinase with immunoglobulin-like and EGF-like domains 1

chr1_+_47489239 1.622 NM_178033
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr4_-_186577858 1.621 SORBS2
sorbin and SH3 domain containing 2
chr2_-_160472960 1.606 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr9_+_133971862 1.598 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr17_+_38119225 1.596 NM_178171
GSDMA
gasdermin A
chr10_-_116392099 1.574 ABLIM1
actin binding LIM protein 1
chr3_-_114343052 1.572 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr4_-_186733372 1.561 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chrX_-_135749436 1.536 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr1_+_84630374 1.535 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_+_68800003 1.534 NM_001205255
OCLN
occludin
chr11_+_33563772 1.511 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr1_+_66797775 1.505 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr8_-_93111915 1.499 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr15_-_70994608 1.492 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr4_-_138453628 1.471 NM_019035
PCDH18
protocadherin 18
chr11_+_113931228 1.466 NM_001018011
ZBTB16
zinc finger and BTB domain containing 16
chr9_-_14398981 1.456 NM_001190738
NFIB
nuclear factor I/B
chr4_-_159093523 1.449 FAM198B
family with sequence similarity 198, member B
chr6_+_142622797 1.437 NM_001032394
NM_001032395
NM_020455
NM_198569
GPR126



G protein-coupled receptor 126



chr5_-_168271852 1.435


chr11_+_59522905 1.433 STX3
syntaxin 3
chr19_-_19049790 1.426 NM_001145724
HOMER3
homer homolog 3 (Drosophila)
chr3_+_136649316 1.424 NM_001190796
NCK1
NCK adaptor protein 1
chr3_-_64211111 1.415 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr11_+_101983170 1.393 NM_001195045
YAP1
Yes-associated protein 1
chr1_-_182357757 1.389 GLUL
glutamate-ammonia ligase
chr9_+_133971902 1.387 AIF1L
allograft inflammatory factor 1-like
chr3_-_122512526 1.363 NM_024610
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr1_-_47695442 1.360 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chrX_+_86772714 1.356 NM_019117
NM_057162
KLHL4

kelch-like 4 (Drosophila)

chr4_-_186578122 1.347 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chrX_-_45060081 1.346 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr12_-_71031174 1.328 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr18_+_77253324 1.327 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr7_-_86688944 1.321 NM_001142749
KIAA1324L
KIAA1324-like
chr19_+_30863318 1.303 NM_014717
ZNF536
zinc finger protein 536
chrX_-_10544852 1.296 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chr3_-_52479042 1.283 NM_020163
SEMA3G
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr8_-_93115453 1.277 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr16_+_30406711 1.276 NM_152652
ZNF48
zinc finger protein 48
chr17_-_67057046 1.267 NM_080283
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr2_-_242556883 1.265 NM_001164356
THAP4
THAP domain containing 4
chr9_-_123476578 1.262 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr13_+_103459495 1.262 NM_001204425
BIVM-ERCC5
BIVM
BIVM-ERCC5 readthrough
basic, immunoglobulin-like variable motif containing
chr18_+_20735788 1.258 NM_138375
CABLES1
Cdk5 and Abl enzyme substrate 1
chr9_-_14313509 1.258 NFIB
nuclear factor I/B
chr4_+_108910869 1.253 NM_001184705
NM_005327
HADH

hydroxyacyl-CoA dehydrogenase

chr4_-_104020964 1.251 NM_020139
BDH2
3-hydroxybutyrate dehydrogenase, type 2
chr3_+_25469833 1.251 NM_000965
RARB
retinoic acid receptor, beta
chr10_-_116286661 1.246 NM_006720
ABLIM1
actin binding LIM protein 1
chr8_-_28243941 1.246 NM_018660
ZNF395
zinc finger protein 395
chrX_+_135251454 1.242 NM_001159704
FHL1
four and a half LIM domains 1
chr10_+_63808968 1.239 NM_001244638
ARID5B
AT rich interactive domain 5B (MRF1-like)
chrX_-_19817854 1.235 SH3KBP1
SH3-domain kinase binding protein 1
chr7_+_134832765 1.230 NM_018295
TMEM140
transmembrane protein 140
chr2_+_189839132 1.225 COL3A1
collagen, type III, alpha 1
chr16_+_30389632 1.225 NM_001214906
NM_001214907
ZNF48

zinc finger protein 48

chr10_-_116286570 1.208 ABLIM1
actin binding LIM protein 1
chrX_+_135251795 1.204 NM_001167819
FHL1
four and a half LIM domains 1
chr14_+_91580713 1.198 C14orf159
chromosome 14 open reading frame 159
chr1_+_212475147 1.182 NM_001199756
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr11_+_92085261 1.178 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr18_-_53257033 1.174 NM_001243227
NM_001243228
TCF4

transcription factor 4

chr4_-_186877869 1.165 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr18_-_53303129 1.160 NM_001243226
TCF4
transcription factor 4
chrX_+_100333835 1.159 NM_021637
TMEM35
transmembrane protein 35
chr20_+_42574535 1.151 NM_001098798
TOX2
TOX high mobility group box family member 2
chr9_+_66553254 1.151 MGC21881
uncharacterized locus MGC21881
chr16_+_30406432 1.149 NM_001214909
ZNF48
zinc finger protein 48
chr3_-_15839674 1.144 NM_001195098
ANKRD28
ankyrin repeat domain 28
chrX_-_100914816 1.135 NM_014782
NM_177949
ARMCX2

armadillo repeat containing, X-linked 2

chr14_+_91580467 1.117 C14orf159
chromosome 14 open reading frame 159
chr17_-_66951381 1.116 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr6_+_144612872 1.113 NM_007124
UTRN
utrophin
chr21_+_33784751 1.113 NM_058187
C21orf63
chromosome 21 open reading frame 63
chr20_+_11898536 1.108 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr3_-_18480203 1.105 NM_001131010
SATB1
SATB homeobox 1
chr14_+_91580967 1.102 NM_001102367
C14orf159
chromosome 14 open reading frame 159
chr14_+_77228132 1.098 NM_014909
VASH1
vasohibin 1
chr1_-_249120063 1.097 NM_030645
SH3BP5L
SH3-binding domain protein 5-like
chr12_+_9142136 1.095 NM_005810
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr11_+_123986103 1.084 NM_001130142
NM_014622
NM_198315
VWA5A


von Willebrand factor A domain containing 5A


chrX_+_107683015 1.082 NM_000495
NM_033380
COL4A5

collagen, type IV, alpha 5

chr6_+_155538096 1.073 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr1_+_33004771 1.067 NM_001040441
ZBTB8A
zinc finger and BTB domain containing 8A
chr11_+_6897855 1.058 NM_207186
OR10A4
olfactory receptor, family 10, subfamily A, member 4
chr14_+_53019865 1.054 NM_001099652
GPR137C
G protein-coupled receptor 137C
chr12_-_6233684 1.053 NM_000552
VWF
von Willebrand factor
chr9_+_97521930 1.044 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chr1_+_155099935 1.036 EFNA1
ephrin-A1
chr15_-_59665053 1.024 MYO1E
myosin IE
chr13_-_45048436 1.022 NM_001243798
TSC22D1
TSC22 domain family, member 1
chr9_-_75567915 1.021 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr6_+_116832807 1.019 NM_153711
FAM26E
family with sequence similarity 26, member E
chrX_-_19688991 1.019 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr18_-_52969714 1.013 NM_001243236
TCF4
transcription factor 4
chr1_-_156051788 1.005 NM_001093725
MEX3A
mex-3 homolog A (C. elegans)
chr3_-_168864066 1.003 NM_001105077
NM_001163999
NM_005241
MECOM


MDS1 and EVI1 complex locus


chr19_+_18118921 0.995 NM_015683
ARRDC2
arrestin domain containing 2
chr12_+_13349720 0.994 EMP1
epithelial membrane protein 1
chr12_-_59314297 0.986 LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr21_+_35190586 0.979 ITSN1
intersectin 1 (SH3 domain protein)
chr4_-_159093717 0.975 NM_016613
FAM198B
family with sequence similarity 198, member B
chrX_-_119709618 0.971 NM_003588
CUL4B
cullin 4B
chr10_-_74283693 0.964 NM_001195519
MICU1
mitochondrial calcium uptake 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.51 9.36e-05 GO:0007156 homophilic cell adhesion
1.61 2.39e-02 GO:0006325 chromatin organization

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.50 4.31e-03 GO:0005509 calcium ion binding
1.49 4.58e-02 GO:0008092 cytoskeletal protein binding