Motif ID: T.p2

Z-value: 0.642


Transcription factors associated with T.p2:

Gene SymbolEntrez IDGene Name
T 6862 T, brachyury homolog (mouse)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
Tchr6_-_166582129-0.164.4e-01Click!


Activity profile for motif T.p2.

activity profile for motif T.p2


Sorted Z-values histogram for motif T.p2

Sorted Z-values for motif T.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of T.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_25958245 2.225 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_25958257 1.666 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_25958217 1.565 LGALS9
lectin, galactoside-binding, soluble, 9
chr12_+_124773709 1.531 NM_181709
FAM101A
family with sequence similarity 101, member A
chr17_+_25958192 1.504 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_25958151 1.451 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr19_-_17958773 1.283 JAK3
Janus kinase 3
chr5_+_54320083 1.237 NM_002104
GZMK
granzyme K (granzyme 3; tryptase II)
chr1_-_205290756 1.050 NM_030952
NUAK2
NUAK family, SNF1-like kinase, 2
chr15_+_40861509 0.930 RPUSD2
RNA pseudouridylate synthase domain containing 2
chr1_+_28585959 0.911 NM_031459
SESN2
sestrin 2
chr8_-_145060594 0.905 NM_032789
PARP10
poly (ADP-ribose) polymerase family, member 10
chr2_-_152146373 0.837 NM_004688
NMI
N-myc (and STAT) interactor
chrX_+_128913881 0.806 NM_018990
SASH3
SAM and SH3 domain containing 3
chr15_+_60296506 0.749 FOXB1
forkhead box B1
chr15_+_60296420 0.727 NM_012182
FOXB1
forkhead box B1
chrX_+_128913897 0.712 SASH3
SAM and SH3 domain containing 3
chr19_-_44174497 0.699 NM_001005376
NM_001005377
NM_002659
PLAUR


plasminogen activator, urokinase receptor


chr5_+_113698304 0.659 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr16_+_57653649 0.657 GPR56
G protein-coupled receptor 56
chr8_-_145060563 0.594 PARP10
poly (ADP-ribose) polymerase family, member 10
chr6_+_109762204 0.590 SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr12_-_52779362 0.583 NM_033045
KRT84
keratin 84
chr5_+_96212167 0.574 ERAP2
endoplasmic reticulum aminopeptidase 2
chr11_+_69061599 0.539 NM_138768
MYEOV
myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chr15_+_40861491 0.536 RPUSD2
RNA pseudouridylate synthase domain containing 2
chr17_+_34431219 0.527 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr2_+_171571800 0.521 NM_001003845
SP5
Sp5 transcription factor
chr3_-_52444016 0.510 BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr5_+_96211643 0.503 NM_001130140
NM_022350
ERAP2

endoplasmic reticulum aminopeptidase 2

chr16_+_25228282 0.488 NM_001169
AQP8
aquaporin 8
chr17_+_8214139 0.482 NM_025014
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr3_-_119582422 0.465 GSK3B
glycogen synthase kinase 3 beta
chr3_-_52443893 0.454 NM_004656
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr2_+_171572698 0.453 SP5
Sp5 transcription factor
chr14_+_95078713 0.443 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr1_-_26633110 0.424 NM_001077262
NM_183008
UBXN11

UBX domain protein 11

chr11_-_64703334 0.408 NM_130769
GPHA2
glycoprotein hormone alpha 2
chr14_+_75894508 0.407 NM_001135047
JDP2
Jun dimerization protein 2
chr16_-_67965754 0.391 NM_001907
CTRL
chymotrypsin-like
chr10_+_111765725 0.385 NM_019903
ADD3
adducin 3 (gamma)
chr1_+_26737306 0.382 LIN28A
lin-28 homolog A (C. elegans)
chr11_-_7847518 0.380 NM_153445
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr2_-_69098502 0.375 NM_014482
BMP10
bone morphogenetic protein 10
chr6_-_31620142 0.359 NM_001098534
BAG6
BCL2-associated athanogene 6
chr17_+_25799024 0.357 NM_014238
KSR1
kinase suppressor of ras 1
chrX_-_53629607 0.356 HUWE1
HECT, UBA and WWE domain containing 1
chr1_+_46379258 0.348 MAST2
microtubule associated serine/threonine kinase 2
chr8_+_22462532 0.345 NM_021174
KIAA1967
KIAA1967
chr12_-_52867521 0.343 NM_173086
KRT6C
keratin 6C
chr20_-_62199106 0.340 NM_033405
PRIC285
peroxisomal proliferator-activated receptor A interacting complex 285
chr2_-_100722328 0.338 AFF3
AF4/FMR2 family, member 3
chr4_-_73434467 0.336 NM_014243
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr11_+_9779832 0.330 LOC283104
uncharacterized LOC283104
chr8_-_119123804 0.328 NM_000127
EXT1
exostosin 1
chr11_-_66112537 0.328 NM_001024957
NM_015399
BRMS1

breast cancer metastasis suppressor 1

chr17_+_3118911 0.326 NM_014565
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr1_-_12908141 0.325 NM_001146181
HNRNPCL1
LOC649330
heterogeneous nuclear ribonucleoprotein C-like 1
heterogeneous nuclear ribonucleoprotein C-like
chr19_-_44831907 0.324 ZFP112
zinc finger protein 112 homolog (mouse)
chr5_+_35856990 0.320 NM_002185
IL7R
interleukin 7 receptor
chr5_+_14664764 0.308 NM_138348
FAM105B
family with sequence similarity 105, member B
chr17_+_7533452 0.306 NM_001040
NM_001146279
NM_001146280
NM_001146281
SHBG



sex hormone-binding globulin



chr14_-_107113943 0.302 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr11_+_61447816 0.299 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr5_+_31799030 0.297 NM_178140
PDZD2
PDZ domain containing 2
chr19_-_38188344 0.296 ZNF607
zinc finger protein 607
chr22_-_41215251 0.296 NM_006358
SLC25A17
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr1_+_26737232 0.284 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr10_+_70847817 0.282 NM_002727
SRGN
serglycin
chr15_-_80263460 0.277 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr11_-_111750144 0.264 NM_138378
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr11_-_113577023 0.258 NM_030770
TMPRSS5
transmembrane protease, serine 5
chr7_-_16505292 0.256 NM_015464
SOSTDC1
sclerostin domain containing 1
chrM_+_9217 0.254


chr11_-_7818488 0.251 NM_153444
OR5P2
olfactory receptor, family 5, subfamily P, member 2
chr21_+_25801042 0.240 FLJ42200
FLJ42200 protein
chr4_+_124317884 0.240 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr12_-_53097246 0.234 NM_175078
KRT77
keratin 77
chr17_-_49124128 0.229 NM_001251971
SPAG9
sperm associated antigen 9
chr2_+_223162865 0.225 NM_153038
CCDC140
coiled-coil domain containing 140
chr9_-_37034358 0.223 NM_016734
PAX5
paired box 5
chr6_-_130536417 0.220 NM_152552
SAMD3
sterile alpha motif domain containing 3
chr17_-_79881304 0.216 NM_032711
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr18_+_54424444 0.211 WDR7
WD repeat domain 7
chr12_-_53074172 0.210 NM_006121
KRT1
keratin 1
chr11_+_117947726 0.206 NM_001083947
NM_001173551
NM_001173552
NM_019894
TMPRSS4



transmembrane protease, serine 4



chr17_+_34538464 0.205 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr1_+_205198058 0.202 NM_001242925
TMCC2
transmembrane and coiled-coil domain family 2
chr2_+_228678556 0.201 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr19_-_55767103 0.199 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr10_+_70847857 0.196 SRGN
serglycin
chr1_-_117210301 0.194 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chr11_-_124806302 0.194 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr2_+_176972005 0.193 NM_021192
HOXD11
homeobox D11
chr11_-_62689011 0.190 NM_000738
CHRM1
cholinergic receptor, muscarinic 1
chr11_+_117947785 0.188 TMPRSS4
transmembrane protease, serine 4
chr5_+_113698015 0.185 NM_021614
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr19_-_13947101 0.185 LOC284454
uncharacterized LOC284454
chrY_+_24636543 0.177 NM_001002758
NM_004676
PRY2
PRY
PTPN13-like, Y-linked 2
PTPN13-like, Y-linked
chr17_+_8213555 0.171 NM_173728
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr9_-_36276930 0.169 NM_001128227
NM_001190388
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chrY_-_24242153 0.168 NM_001002758
NM_004676
PRY2
PRY
PTPN13-like, Y-linked 2
PTPN13-like, Y-linked
chr2_-_113542970 0.168 NM_000575
IL1A
interleukin 1, alpha
chr2_-_175113197 0.166 OLA1
Obg-like ATPase 1
chr10_-_61122219 0.165 NM_001001971
NM_001166698
NM_198215
FAM13C


family with sequence similarity 13, member C


chr17_+_56232493 0.165 NM_012374
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chr4_+_8582216 0.163 NM_080819
GPR78
G protein-coupled receptor 78
chr6_-_31619481 0.163


chr2_-_175113284 0.162 NM_001011708
NM_013341
OLA1

Obg-like ATPase 1

chr17_+_1619816 0.161 NM_001163673
NM_152348
WDR81

WD repeat domain 81

chr3_+_137728949 0.159 NM_016369
CLDN18
claudin 18
chr3_-_71542628 0.159 FOXP1
forkhead box P1
chr3_-_10332408 0.158 NM_001134941
NM_016362
GHRL

ghrelin/obestatin prepropeptide

chr3_+_128532267 0.158


chr11_-_111749810 0.157 FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr19_-_44174271 0.156 PLAUR
plasminogen activator, urokinase receptor
chr5_+_14664803 0.154 FAM105B
family with sequence similarity 105, member B
chr6_+_83072922 0.153 NM_006670
TPBG
trophoblast glycoprotein
chr17_+_56414563 0.152 LOC100506779
uncharacterized LOC100506779
chr16_+_67906924 0.150 NM_014329
EDC4
enhancer of mRNA decapping 4
chr17_-_74533623 0.142 NM_134268
CYGB
cytoglobin
chr10_+_114133838 0.141 NM_203379
ACSL5
acyl-CoA synthetase long-chain family member 5
chr3_+_38307297 0.140 NM_004256
SLC22A13
solute carrier family 22 (organic anion transporter), member 13
chrX_+_91089658 0.136 NM_014522
NM_032968
NM_032969
PCDH11X


protocadherin 11 X-linked


chr11_-_3692544 0.135 NM_020402
CHRNA10
cholinergic receptor, nicotinic, alpha 10
chr7_+_100027404 0.135 MEPCE
methylphosphate capping enzyme
chr11_-_44972227 0.133 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr14_-_21572789 0.132 NM_001102454
ZNF219
zinc finger protein 219
chr20_+_35973083 0.132 NM_005417
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr2_-_175113257 0.132 OLA1
Obg-like ATPase 1
chr6_-_74229094 0.130 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr14_-_106692107 0.127 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr11_+_27015627 0.127 NM_203371
FIBIN
fin bud initiation factor homolog (zebrafish)
chrX_+_16804531 0.127 NM_001168683
NM_018360
TXLNG

taxilin gamma

chrM_+_8857 0.125


chr14_+_51026742 0.122 NM_015915
NM_181598
ATL1

atlastin GTPase 1

chr5_-_132112887 0.119 NM_001098811
NM_001098812
NM_015146
SEPT8


septin 8


chrX_-_19688991 0.119 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr17_-_61988614 0.115 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chr4_-_186456580 0.114 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chrM_-_9203 0.113


chr11_-_57195052 0.113 NM_017611
SLC43A3
solute carrier family 43, member 3
chr7_-_36764000 0.112 NM_001177506
NM_001177507
NM_001637
AOAH


acyloxyacyl hydrolase (neutrophil)


chr16_+_67907018 0.112 EDC4
enhancer of mRNA decapping 4
chrX_+_69642880 0.111 NM_001171191
NM_001171192
NM_001171193
NM_017711
GDPD2



glycerophosphodiester phosphodiesterase domain containing 2



chr17_-_61950997 0.109 NM_020991
NM_022644
NM_022645
CSH2


chorionic somatomammotropin hormone 2


chr7_+_148844440 0.108 NM_170686
ZNF398
zinc finger protein 398
chr9_-_130533509 0.108 NM_001252334
NM_005489
SH2D3C

SH2 domain containing 3C

chr5_+_175665337 0.107 NM_198567
C5orf25
chromosome 5 open reading frame 25
chr15_-_40600025 0.105 PLCB2
phospholipase C, beta 2
chr6_+_36922208 0.104 NM_153370
PI16
peptidase inhibitor 16
chr2_-_175113240 0.104 OLA1
Obg-like ATPase 1
chr10_-_123356158 0.102 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr11_-_65686439 0.102 NM_001135635
NM_031450
C11orf68

chromosome 11 open reading frame 68

chr19_-_10514154 0.101 CDC37
cell division cycle 37 homolog (S. cerevisiae)
chr16_+_77233348 0.101 NM_001129979
SYCE1L
synaptonemal complex central element protein 1-like
chr2_+_219081864 0.100 NM_152862
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr15_+_63889551 0.100 NM_203373
FBXL22
F-box and leucine-rich repeat protein 22
chr4_-_7436614 0.100 NM_001085382
PSAPL1
prosaposin-like 1 (gene/pseudogene)
chr11_-_45928832 0.100 NM_001080446
C11orf94
chromosome 11 open reading frame 94
chr12_-_56848398 0.099 NM_012064
MIP
major intrinsic protein of lens fiber
chr12_-_91576579 0.097 DCN
decorin
chr17_+_79609298 0.097 NM_031945
TSPAN10
tetraspanin 10
chr7_+_148844685 0.096 ZNF398
zinc finger protein 398
chr1_-_12677347 0.096 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr3_-_93747453 0.092 NM_001001850
STX19
syntaxin 19
chr1_+_215178884 0.092 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr7_-_76038894 0.091 NM_080744
SRCRB4D
scavenger receptor cysteine rich domain containing, group B (4 domains)
chr1_-_155231941 0.091 SCAMP3
secretory carrier membrane protein 3
chrX_-_47863260 0.091 NM_001007088
NM_006962
NM_001178099
ZNF182


zinc finger protein 182


chr19_+_55281262 0.091 NM_014218
KIR2DL1
KIR2DS4
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
chr6_+_132873829 0.091 NM_053278
TAAR8
trace amine associated receptor 8
chrX_+_48336379 0.090 NM_177434
FTSJ1
FtsJ homolog 1 (E. coli)
chr14_-_107218786 0.088 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr9_-_15250113 0.088 NM_001168342
TTC39B
tetratricopeptide repeat domain 39B
chr7_+_86274076 0.087 GRM3
glutamate receptor, metabotropic 3
chr6_+_33387846 0.086 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chr17_-_39211462 0.086 NM_033032
KRTAP2-2
keratin associated protein 2-2
chr11_+_15133969 0.086 NM_001031853
INSC
inscuteable homolog (Drosophila)
chr5_+_140864626 0.086 NM_018928
NM_032406
PCDHGC4

protocadherin gamma subfamily C, 4

chr12_-_95942570 0.083 NM_001042403
USP44
ubiquitin specific peptidase 44
chr13_+_109281569 0.082 NM_001198950
MYO16
myosin XVI
chr5_-_33984688 0.081 NM_001012509
NM_016180
SLC45A2

solute carrier family 45, member 2

chr20_-_52199635 0.080 NM_006526
ZNF217
zinc finger protein 217
chr19_-_8212367 0.080 NM_032447
FBN3
fibrillin 3
chr3_+_167453431 0.080 NM_001122752
NM_005025
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr6_-_6320875 0.078 F13A1
coagulation factor XIII, A1 polypeptide
chr11_-_124767681 0.077 NM_019055
ROBO4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr3_+_133502876 0.075 NM_021203
SRPRB
signal recognition particle receptor, B subunit
chr17_-_61973870 0.075 NM_001317
CSH1
chorionic somatomammotropin hormone 1 (placental lactogen)
chr1_-_238054221 0.074 NM_021186
ZP4
zona pellucida glycoprotein 4
chr14_-_45603668 0.073 NM_002013
FKBP3
FK506 binding protein 3, 25kDa
chr13_+_99058147 0.073


chr17_-_10452939 0.073 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chrX_+_37639306 0.073 CYBB
cytochrome b-245, beta polypeptide
chr7_+_100027253 0.073 NM_019606
MEPCE
methylphosphate capping enzyme
chr7_-_138363789 0.072 NM_001139456
SVOPL
SVOP-like
chr3_-_71632741 0.072 NM_001244808
NM_001012505
NM_001244810
NM_032682
FOXP1



forkhead box P1



chr1_-_114414245 0.071 NM_001193431
NM_012411
NM_015967
PTPN22


protein tyrosine phosphatase, non-receptor type 22 (lymphoid)


chr21_+_45725058 0.071 PFKL
phosphofructokinase, liver

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.36 3.61e-03 GO:0007267 cell-cell signaling
2.15 3.61e-03 GO:0007154 cell communication

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.80 6.86e-05 GO:0005576 extracellular region
2.61 1.74e-02 GO:0009986 cell surface

Nothing significant found in function category.