Motif ID: TBP.p2

Z-value: 2.025


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
TBP 6908 TATA box binding protein

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
TBPchr6_+_170863420-0.462.2e-02Click!


Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_169703178 20.475 NM_000450
 SELE
selectin E
chr19_+_10381763 19.383 ICAM1
intercellular adhesion molecule 1
chr21_+_26934440 13.068 MIR155HG
MIR155 host gene (non-protein coding)
chr11_-_102651321 10.707 NM_002425
 MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr15_+_62359175 10.279 NM_207322
 C2CD4A
C2 calcium-dependent domain containing 4A
chr1_-_95007139 9.463 NM_001178096
NM_001993
 F3

coagulation factor III (thromboplastin, tissue factor)

chr4_-_74904329 9.346 NM_002090
 CXCL3
chemokine (C-X-C motif) ligand 3
chr4_+_74606222 8.145 NM_000584
 IL8
interleukin 8
chr15_-_62457481 7.928 NM_001007595
 C2CD4B
C2 calcium-dependent domain containing 4B
chr16_+_57406398 7.696 NM_002996
 CX3CL1
chemokine (C-X3-C motif) ligand 1
chr4_+_74735107 7.641 NM_001511
 CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr2_+_228678556 7.396 NM_001130046
NM_004591
 CCL20

chemokine (C-C motif) ligand 20

chr1_+_37940180 6.246 ZC3H12A
zinc finger CCCH-type containing 12A
chr4_-_74964836 5.547 CXCL2
chemokine (C-X-C motif) ligand 2
chr6_+_14118002 5.165 CD83
CD83 molecule
chr14_-_55369163 5.038 NM_000161
NM_001024024
NM_001024070
NM_001024071
 GCH1



GTP cyclohydrolase 1



chr17_+_32582295 4.934 NM_002982
 CCL2
chemokine (C-C motif) ligand 2
chr6_+_127898318 4.523 NM_001010905
 C6orf58
chromosome 6 open reading frame 58
chr19_+_676346 4.451 NM_005860
 FSTL3
follistatin-like 3 (secreted glycoprotein)
chr19_+_12902295 4.303 NM_002229
 JUNB
jun B proto-oncogene

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 73 entries
enrichment   p-value GO term description
15.90 1.24e-02 GO:0048246 macrophage chemotaxis
10.60 7.58e-04 GO:0042743 hydrogen peroxide metabolic process
10.60 2.31e-02 GO:0042744 hydrogen peroxide catabolic process
7.95 3.52e-02 GO:0070301 cellular response to hydrogen peroxide
7.16 5.65e-03 GO:0072593 reactive oxygen species metabolic process
6.98 7.05e-03 GO:0051258 protein polymerization
6.82 8.72e-03 GO:0034614 cellular response to reactive oxygen species
6.66 1.07e-02 GO:0030595 leukocyte chemotaxis
6.36 1.57e-03 GO:0060326 cell chemotaxis
6.22 7.14e-07 GO:0006334 nucleosome assembly
5.90 1.77e-06 GO:0031497 chromatin assembly
5.83 3.90e-03 GO:0034599 cellular response to oxidative stress
5.61 4.13e-06 GO:0034728 nucleosome organization
5.40 7.85e-06 GO:0065004 protein-DNA complex assembly
5.11 1.94e-05 GO:0071824 protein-DNA complex subunit organization
4.76 2.56e-05 GO:0006323 DNA packaging
4.29 3.70e-02 GO:0000302 response to reactive oxygen species
4.28 7.68e-03 GO:0008217 regulation of blood pressure
4.24 3.75e-04 GO:0006333 chromatin assembly or disassembly
4.08 3.16e-04 GO:0071103 DNA conformation change

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
10.09 2.45e-17 GO:0045095 keratin filament
9.54 3.38e-11 GO:0000786 nucleosome
8.84 4.10e-02 GO:0005859 muscle myosin complex
8.84 4.10e-02 GO:0032982 myosin filament
6.96 6.14e-19 GO:0005882 intermediate filament
6.04 1.07e-16 GO:0045111 intermediate filament cytoskeleton
6.03 1.49e-07 GO:0032993 protein-DNA complex
3.59 3.90e-23 GO:0005615 extracellular space
3.06 9.36e-21 GO:0044421 extracellular region part
2.77 7.90e-03 GO:0000785 chromatin
2.50 3.97e-26 GO:0005576 extracellular region
2.20 5.88e-08 GO:0044430 cytoskeletal part
1.93 1.91e-07 GO:0005856 cytoskeleton
1.45 1.50e-03 GO:0043228 non-membrane-bounded organelle
1.45 1.50e-03 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
31.80 1.06e-05 GO:0046870 cadmium ion binding
12.45 2.44e-13 GO:0008009 chemokine activity
11.23 2.09e-12 GO:0042379 chemokine receptor binding
9.36 4.82e-02 GO:0005212 structural constituent of eye lens
6.12 1.38e-03 GO:0005507 copper ion binding
5.74 8.40e-15 GO:0005125 cytokine activity
5.66 2.39e-02 GO:0019825 oxygen binding
5.48 2.27e-12 GO:0005126 cytokine receptor binding
4.62 4.60e-08 GO:0001664 G-protein-coupled receptor binding
4.50 8.05e-04 GO:0005179 hormone activity
3.64 5.02e-03 GO:0046906 tetrapyrrole binding
3.62 1.04e-02 GO:0020037 heme binding
3.00 4.83e-02 GO:0001871 pattern binding
3.00 4.83e-02 GO:0030247 polysaccharide binding
2.93 4.42e-10 GO:0005198 structural molecule activity
2.92 9.32e-03 GO:0005506 iron ion binding
2.57 2.61e-12 GO:0005102 receptor binding
2.35 1.07e-02 GO:0030246 carbohydrate binding
1.22 1.61e-03 GO:0005515 protein binding