Motif ID: TBX4,5.p2

Z-value: 1.322


Transcription factors associated with TBX4,5.p2:

Gene SymbolEntrez IDGene Name
TBX4 9496 T-box 4
TBX5 6910 T-box 5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
TBX5chr12_-_1148417020.154.8e-01Click!
TBX4chr17_+_59529778-0.087.2e-01Click!


Activity profile for motif TBX4,5.p2.

activity profile for motif TBX4,5.p2


Sorted Z-values histogram for motif TBX4,5.p2

Sorted Z-values for motif TBX4,5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBX4,5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_54421269 2.842 NM_130851
 BMP4
bone morphogenetic protein 4
chr8_+_120220554 2.621 NM_052886
 MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr7_+_30951414 2.547 NM_198098
 AQP1
aquaporin 1 (Colton blood group)
chr11_-_33913835 2.385 NM_005574
 LMO2
LIM domain only 2 (rhombotin-like 1)
chrX_-_117250624 1.940 NM_001168302
NM_001168303
 KLHL13

kelch-like 13 (Drosophila)

chr2_-_61697846 1.886 NM_014709
 USP34
ubiquitin specific peptidase 34
chr5_-_43313492 1.877 HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr17_+_68165660 1.820 NM_000891
 KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr3_+_39851028 1.747 NM_015460
 MYRIP
myosin VIIA and Rab interacting protein
chr11_-_119234628 1.721 USP2
ubiquitin specific peptidase 2
chr4_+_156587861 1.677 NM_000856
NM_001130682
NM_001130686
NM_001130687
NM_001130683
NM_001130685
 GUCY1A3





guanylate cyclase 1, soluble, alpha 3





chr11_-_33891258 1.661 LMO2
LIM domain only 2 (rhombotin-like 1)
chr4_-_99579540 1.661 NM_005723
 TSPAN5
tetraspanin 5
chr1_+_100111430 1.606 NM_017734
 PALMD
palmdelphin
chr5_-_43313581 1.554 NM_001098272
NM_002130
 HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr17_+_61562177 1.547 NM_001178057
NM_152830
 ACE

angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

chr2_-_61697899 1.546 USP34
ubiquitin specific peptidase 34
chr4_+_156588811 1.501 NM_001130684
 GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr3_-_158390266 1.483 NM_020169
 LXN
latexin
chr2_+_61108702 1.482 REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
3.33 4.56e-02 GO:0016126 sterol biosynthetic process
1.63 3.23e-02 GO:0032583 regulation of gene-specific transcription
1.07 2.32e-02 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.39 3.79e-03 GO:0005925 focal adhesion
2.27 1.04e-02 GO:0005924 cell-substrate adherens junction
2.19 2.20e-02 GO:0030055 cell-substrate junction
2.10 1.63e-05 GO:0016323 basolateral plasma membrane
1.98 2.55e-02 GO:0005912 adherens junction
1.89 4.51e-02 GO:0070161 anchoring junction
1.81 4.75e-02 GO:0005911 cell-cell junction
1.42 2.12e-02 GO:0044432 endoplasmic reticulum part
1.41 9.44e-04 GO:0005783 endoplasmic reticulum
1.29 1.52e-02 GO:0012505 endomembrane system
1.24 1.58e-02 GO:0044459 plasma membrane part
1.13 4.09e-06 GO:0005737 cytoplasm
1.13 1.25e-02 GO:0044444 cytoplasmic part

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
3.59 8.54e-04 GO:0003823 antigen binding