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• Activity deltas table
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Motif ID: TFAP2B.p2

Z-value: 1.103

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_-_38069082	3.511		SHB	Src homology 2 domain containing adaptor protein B
chr19_+_45504686	2.509	NM_006509	RELB	v-rel reticuloendotheliosis viral oncogene homolog B
chr6_-_160114318	2.343	NM_000636 NM_001024465 NM_001024466	SOD2	superoxide dismutase 2, mitochondrial
chr6_-_160114186	1.958		SOD2	superoxide dismutase 2, mitochondrial
chr7_+_18126543	1.665	NM_001204144	HDAC9	histone deacetylase 9
chr5_+_10564431	1.597	NM_001164440	ANKRD33B	ankyrin repeat domain 33B
chr9_-_38069207	1.579	NM_003028	SHB	Src homology 2 domain containing adaptor protein B
chr8_-_80679897	1.566	NM_001040708 NM_012258	HEY1	hairy/enhancer-of-split related with YRPW motif 1
chr11_+_369723	1.232	NM_178537	B4GALNT4	beta-1,4-N-acetyl-galactosaminyl transferase 4
chr14_-_55369163	1.189	NM_000161 NM_001024024 NM_001024070 NM_001024071	GCH1	GTP cyclohydrolase 1
chr7_+_6144504	1.186	NM_032172	USP42	ubiquitin specific peptidase 42
chr1_-_184943673	1.133	NM_052966	FAM129A	family with sequence similarity 129, member A
chr8_-_48650683	1.102		CEBPD	CCAAT/enhancer binding protein (C/EBP), delta
chr1_-_184943532	1.084		FAM129A	family with sequence similarity 129, member A
chr6_+_135502477	1.068		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr17_+_36861398	1.035		MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr6_+_37137882	1.035	NM_001243186 NM_002648	PIM1	pim-1 oncogene
chr1_-_33430285	1.024	NM_001127361 NM_153341	RNF19B	ring finger protein 19B
chr16_+_11762235	1.012	NM_003498	SNN	stannin
chr3_+_72937168	1.003	NM_001080393	GXYLT2	glucoside xylosyltransferase 2
chr8_-_141645603	0.996	NM_001164623 NM_012154	EIF2C2	eukaryotic translation initiation factor 2C, 2
chr8_+_17354562	0.995	NM_001008539	SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr17_+_15848230	0.930	NM_000676	ADORA2B	adenosine A2b receptor
chr8_+_81398416	0.923	NM_001105539 NM_023929	ZBTB10	zinc finger and BTB domain containing 10
chr2_-_7005764	0.918	NM_207315	CMPK2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr4_+_139936938	0.915	NM_012118	CCRN4L	CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr6_+_135502445	0.913	NM_001130172 NM_001130173 NM_001161656 NM_001161657 NM_001161658 NM_001161659 NM_001161660 NM_005375	MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr11_+_109964086	0.904	NM_033390	ZC3H12C	zinc finger CCCH-type containing 12C
chr6_+_135502521	0.901		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr6_+_4776826	0.899		CDYL	chromodomain protein, Y-like
chr17_+_15848422	0.870		ADORA2B	adenosine A2b receptor
chr6_+_126111782	0.844	NM_001122842 NM_001199621 NM_181782	NCOA7	nuclear receptor coactivator 7
chr6_+_4776641	0.838	NM_004824	CDYL	chromodomain protein, Y-like
chr7_+_6144589	0.837		USP42	ubiquitin specific peptidase 42
chr6_+_83073954	0.830	NM_001166392	TPBG	trophoblast glycoprotein
chr2_+_234263153	0.828		DGKD	diacylglycerol kinase, delta 130kDa
chr8_+_61591358	0.813		CHD7	chromodomain helicase DNA binding protein 7
chr5_-_16936290	0.812		MYO10	myosin X
chr16_-_87903028	0.802	NM_003486	SLC7A5	solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr22_-_43116796	0.802	NM_017436	A4GALT	alpha 1,4-galactosyltransferase
chr1_-_33336289	0.801	NM_001171940 NM_153756	FNDC5	fibronectin type III domain containing 5
chr4_+_103422553	0.801		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr15_+_67358161	0.783		SMAD3	SMAD family member 3
chr20_+_55966440	0.773	NM_017495 NM_183425	RBM38	RNA binding motif protein 38
chr6_+_71998514	0.761		OGFRL1	opioid growth factor receptor-like 1
chr4_-_177713664	0.757	NM_005429	VEGFC	vascular endothelial growth factor C
chr12_-_109251333	0.747	NM_001161330 NM_018984	SSH1	slingshot homolog 1 (Drosophila)
chr6_-_17987852	0.746	NM_001105566 NM_001105567 NM_001105568 NM_001243423 NM_022113	KIF13A	kinesin family member 13A
chr6_+_71998508	0.740		OGFRL1	opioid growth factor receptor-like 1
chr14_-_35344080	0.735		BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr4_-_2758018	0.727	NM_024309	TNIP2	TNFAIP3 interacting protein 2
chr2_-_198175324	0.724		ANKRD44	ankyrin repeat domain 44
chr18_+_8609407	0.723	NM_001025300	RAB12	RAB12, member RAS oncogene family
chr5_+_179234002	0.723	NM_001142299	SQSTM1	sequestosome 1
chr20_+_45523523	0.718		EYA2	eyes absent homolog 2 (Drosophila)
chr20_-_62462568	0.713		ZBTB46	zinc finger and BTB domain containing 46
chr6_+_71998476	0.710	NM_024576	OGFRL1	opioid growth factor receptor-like 1
chr5_-_158636489	0.710	NM_001199383	RNF145	ring finger protein 145
chr15_+_80987609	0.708	NM_021214	FAM108C1	family with sequence similarity 108, member C1
chr1_-_156721501	0.703	NM_004494	HDGF	hepatoma-derived growth factor
chr9_+_116918230	0.702	NM_032888	COL27A1	collagen, type XXVII, alpha 1
chr3_-_127541975	0.698	NM_001003794	MGLL	monoglyceride lipase
chr7_+_73703704	0.694	NM_003388 NM_032421	CLIP2	CAP-GLY domain containing linker protein 2
chr19_+_1941184	0.689		CSNK1G2	casein kinase 1, gamma 2
chr3_+_133292714	0.688		CDV3	CDV3 homolog (mouse)
chr1_-_156721280	0.687		HDGF	hepatoma-derived growth factor
chr6_+_108882068	0.686	NM_001455	FOXO3	forkhead box O3
chr14_+_103243832	0.686		TRAF3	TNF receptor-associated factor 3
chr2_-_288181	0.683	NM_001002919	FAM150B	family with sequence similarity 150, member B
chr1_+_16010838	0.678		PLEKHM2	pleckstrin homology domain containing, family M (with RUN domain) member 2
chr2_+_170590454	0.674		KLHL23	kelch-like 23 (Drosophila)
chr11_+_64001974	0.674	NM_001243733 NM_003377	VEGFB	vascular endothelial growth factor B
chr8_-_12612968	0.662	NM_152271	LONRF1	LON peptidase N-terminal domain and ring finger 1
chr2_+_234263141	0.657	NM_152879	DGKD	diacylglycerol kinase, delta 130kDa
chr5_+_127419407	0.656	NM_001046	SLC12A2	solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr2_-_239112317	0.656	NM_030768	ILKAP	integrin-linked kinase-associated serine/threonine phosphatase
chr3_-_127541160	0.656	NM_007283	MGLL	monoglyceride lipase
chr6_-_17987693	0.648		KIF13A	kinesin family member 13A
chr10_-_121632265	0.647	NM_024834	MCMBP	minichromosome maintenance complex binding protein
chr6_+_138188352	0.644	NM_006290	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr1_+_150122415	0.644		PLEKHO1	pleckstrin homology domain containing, family O member 1
chr1_-_229761716	0.634		TAF5L	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr17_-_73874056	0.628		TRIM47	tripartite motif containing 47
chr3_+_53195214	0.621	NM_006254 NM_212539	PRKCD	protein kinase C, delta
chr2_-_197457250	0.615	NM_020760	HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr1_-_6662681	0.606		KLHL21	kelch-like 21 (Drosophila)
chr7_-_559479	0.606	NM_002607 NM_033023	PDGFA	platelet-derived growth factor alpha polypeptide
chr11_-_695402	0.603	NM_021008	DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)
chr16_+_67562704	0.602	NM_024519 NM_001193522	FAM65A	family with sequence similarity 65, member A
chr16_+_57406398	0.598	NM_002996	CX3CL1	chemokine (C-X3-C motif) ligand 1
chr22_+_29279573	0.595	NM_001206998	ZNRF3	zinc and ring finger 3
chr19_+_676346	0.592	NM_005860	FSTL3	follistatin-like 3 (secreted glycoprotein)
chr10_+_28966419	0.591	NM_012342	BAMBI	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
chr12_+_11802642	0.590		ETV6	ets variant 6
chr4_+_4861371	0.589	NM_002448	MSX1	msh homeobox 1
chr5_+_14143287	0.583	NM_007118	TRIO	triple functional domain (PTPRF interacting)
chr4_+_128982483	0.577		LARP1B	La ribonucleoprotein domain family, member 1B
chr8_-_8750739	0.572	NM_004225	MFHAS1	malignant fibrous histiocytoma amplified sequence 1
chr2_+_47168362	0.572		TTC7A	tetratricopeptide repeat domain 7A
chr5_+_139027955	0.571		CXXC5	CXXC finger protein 5
chr14_-_35344526	0.569		BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr20_+_45523505	0.568		EYA2	eyes absent homolog 2 (Drosophila)
chr11_+_93862060	0.568	NM_015368	PANX1	pannexin 1
chr2_+_102314162	0.566	NM_001242560 NM_004834 NM_145686 NM_001242559 NM_145687	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr6_+_160148145	0.564	NM_004906 NM_152858	WTAP	Wilms tumor 1 associated protein
chr13_-_27745952	0.558	NM_182488	USP12	ubiquitin specific peptidase 12
chr2_-_239112193	0.556		ILKAP	integrin-linked kinase-associated serine/threonine phosphatase
chr20_+_388693	0.556	NM_006462 NM_031229	RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr17_+_74380676	0.551	NM_001142601 NM_021972 NM_182965	SPHK1	sphingosine kinase 1
chr2_-_239112331	0.549		ILKAP	integrin-linked kinase-associated serine/threonine phosphatase
chr1_+_150122246	0.548		PLEKHO1	pleckstrin homology domain containing, family O member 1
chr2_+_239335567	0.544	NM_001040445	ASB1	ankyrin repeat and SOCS box containing 1
chr6_+_12012723	0.542	NM_002114	HIVEP1	human immunodeficiency virus type I enhancer binding protein 1
chr2_-_235405692	0.541	NM_005737	ARL4C	ADP-ribosylation factor-like 4C
chr8_+_146277789	0.539	NM_023080	C8orf33	chromosome 8 open reading frame 33
chr5_+_179247841	0.539	NM_003900	SQSTM1	sequestosome 1
chr20_-_47894570	0.537		ZNFX1	zinc finger, NFX1-type containing 1
chr16_+_88519658	0.537		ZFPM1	zinc finger protein, multitype 1
chr21_-_35987144	0.536	NM_004414	RCAN1	regulator of calcineurin 1
chr10_+_82213892	0.536	NM_001128309 NM_030927	TSPAN14	tetraspanin 14
chr8_+_23386468	0.535		SLC25A37	solute carrier family 25, member 37
chr20_+_388963	0.532		RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr1_+_955609	0.530		AGRN	agrin
chr19_+_6531009	0.523	NM_003811	TNFSF9	tumor necrosis factor (ligand) superfamily, member 9
chr1_+_16010816	0.523	NM_015164	PLEKHM2	pleckstrin homology domain containing, family M (with RUN domain) member 2
chr11_+_118307072	0.523	NM_001197104 NM_005933	MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
chr14_+_105781180	0.521		PACS2	phosphofurin acidic cluster sorting protein 2
chr6_-_10419786	0.521	NM_001042425	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr20_+_45523247	0.518	NM_005244 NM_172110	EYA2	eyes absent homolog 2 (Drosophila)
chr5_+_139028025	0.517	NM_016463	CXXC5	CXXC finger protein 5
chr10_+_82214066	0.516		TSPAN14	tetraspanin 14
chr11_-_535532	0.512	NM_001130442 NM_005343 NM_176795	HRAS	v-Ha-ras Harvey rat sarcoma viral oncogene homolog
chr4_+_103422479	0.510	NM_001165412 NM_003998	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr6_+_83073501	0.510		TPBG	trophoblast glycoprotein
chr13_-_27745775	0.510		USP12	ubiquitin specific peptidase 12
chr1_+_955468	0.509	NM_198576	AGRN	agrin
chr6_+_36646455	0.508	NM_000389 NM_001220778	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr12_+_11802905	0.508		ETV6	ets variant 6
chr9_-_22009270	0.507	NM_004936 NM_078487	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr1_+_178063237	0.505		RASAL2	RAS protein activator like 2
chr12_+_121647850	0.502		P2RX4	purinergic receptor P2X, ligand-gated ion channel, 4
chr10_-_25012168	0.500		ARHGAP21	Rho GTPase activating protein 21
chr1_+_27153130	0.499	NM_032283	ZDHHC18	zinc finger, DHHC-type containing 18
chr2_+_150187028	0.497	NM_194317	LYPD6	LY6/PLAUR domain containing 6
chr10_+_30723050	0.494		MAP3K8	mitogen-activated protein kinase kinase kinase 8
chr3_-_37217716	0.492	NM_001134369 NM_006309 NM_017724	LRRFIP2	leucine rich repeat (in FLII) interacting protein 2
chr1_-_205290756	0.492	NM_030952	NUAK2	NUAK family, SNF1-like kinase, 2
chr6_+_108882104	0.491		FOXO3	forkhead box O3
chr3_+_101568325	0.487	NM_031419	NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr18_+_8609670	0.487
chr20_+_56285213	0.485
chr17_+_36861857	0.483	NM_005937	MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr12_+_121647936	0.482		P2RX4	purinergic receptor P2X, ligand-gated ion channel, 4
chr8_-_48650703	0.479	NM_005195	CEBPD	CCAAT/enhancer binding protein (C/EBP), delta
chr5_+_179248089	0.478		SQSTM1	sequestosome 1
chr15_+_75494233	0.477		C15orf39	chromosome 15 open reading frame 39
chr3_-_129325175	0.476	NM_015103	PLXND1	plexin D1
chr2_+_97202463	0.474	NM_212481	ARID5A	AT rich interactive domain 5A (MRF1-like)
chr19_-_47922339	0.469		MEIS3	Meis homeobox 3
chr9_+_132934685	0.463	NM_014286	NCS1	neuronal calcium sensor 1
chr4_+_103422730	0.463		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr14_+_105780903	0.461		PACS2	phosphofurin acidic cluster sorting protein 2
chr1_+_211500147	0.460	NM_001033910	TRAF5	TNF receptor-associated factor 5
chr9_+_137218324	0.460		RXRA	retinoid X receptor, alpha
chr9_+_140500148	0.458		ARRDC1	arrestin domain containing 1
chr11_-_8892909	0.457		ST5	suppression of tumorigenicity 5
chr8_+_146277830	0.456		C8orf33	chromosome 8 open reading frame 33
chr20_+_6748744	0.454	NM_001200	BMP2	bone morphogenetic protein 2
chr8_+_145064583	0.452		GRINA	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr12_+_11802726	0.451	NM_001987	ETV6	ets variant 6
chr1_+_28995214	0.451	NM_006582 NM_024482	GMEB1	glucocorticoid modulatory element binding protein 1
chr20_-_3996035	0.449	NM_007219 NM_001134337 NM_001134338	RNF24	ring finger protein 24
chr7_-_559030	0.448		PDGFA	platelet-derived growth factor alpha polypeptide
chr20_-_43977023	0.444	NM_002999	SDC4	syndecan 4
chr2_-_106810756	0.442		UXS1	UDP-glucuronate decarboxylase 1
chr9_+_115913266	0.441		SLC31A2	solute carrier family 31 (copper transporters), member 2
chr2_-_106810735	0.440		UXS1	UDP-glucuronate decarboxylase 1
chr17_-_79885544	0.440	NM_002359	MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr5_+_14664764	0.439	NM_138348	FAM105B	family with sequence similarity 105, member B
chr14_+_103243813	0.435	NM_001199427 NM_003300 NM_145725 NM_145726	TRAF3	TNF receptor-associated factor 3
chr22_-_50221445	0.434		BRD1	bromodomain containing 1
chr20_+_388717	0.434		RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr1_+_212782103	0.433		ATF3	activating transcription factor 3
chr7_+_4722091	0.430		FOXK1	forkhead box K1
chr1_+_45266035	0.429	NM_004073	PLK3	polo-like kinase 3
chr21_-_45660841	0.428		ICOSLG	inducible T-cell co-stimulator ligand
chr1_-_11120001	0.427		SRM	spermidine synthase
chr12_-_121734474	0.426		CAMKK2	calcium/calmodulin-dependent protein kinase kinase 2, beta
chr8_+_145064167	0.425	NM_000837 NM_001009184	GRINA	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr9_+_114659023	0.424	NM_003358	UGCG	UDP-glucose ceramide glucosyltransferase
chr20_+_61904158	0.422	NM_018209 NM_175609	ARFGAP1	ADP-ribosylation factor GTPase activating protein 1
chr8_+_145064238	0.421		GRINA	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr1_+_178063302	0.418		RASAL2	RAS protein activator like 2
chr4_-_113206883	0.417	NM_052864	TIFA	TRAF-interacting protein with forkhead-associated domain
chr20_-_47894591	0.417	NM_021035	ZNFX1	zinc finger, NFX1-type containing 1
chr5_+_139027907	0.415		CXXC5	CXXC finger protein 5
chr10_+_98592015	0.414	NM_001170765 NM_001170766	LCOR	ligand dependent nuclear receptor corepressor
chr20_+_388941	0.414		RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr15_+_63335086	0.413		TPM1	tropomyosin 1 (alpha)
chr1_+_23037329	0.413	NM_004442 NM_017449	EPHB2	EPH receptor B2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.19	4.26e-26	GO:0044237	cellular metabolic process
1.10	7.26e-25	GO:0009987	cellular process
1.20	1.20e-18	GO:0044260	cellular macromolecule metabolic process
1.14	2.66e-18	GO:0008152	metabolic process
1.14	6.09e-15	GO:0044238	primary metabolic process
1.16	7.03e-13	GO:0043170	macromolecule metabolic process
1.22	9.23e-11	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24	1.96e-10	GO:0048523	negative regulation of cellular process
1.20	2.12e-10	GO:0034641	cellular nitrogen compound metabolic process
1.18	5.88e-10	GO:0071840	cellular component organization or biogenesis
1.18	5.94e-10	GO:0016043	cellular component organization
1.19	6.37e-10	GO:0006807	nitrogen compound metabolic process
1.21	1.22e-09	GO:0071841	cellular component organization or biogenesis at cellular level
1.18	1.42e-09	GO:0031323	regulation of cellular metabolic process
1.21	1.76e-09	GO:0071842	cellular component organization at cellular level
1.22	2.15e-09	GO:0048519	negative regulation of biological process
1.35	4.31e-09	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.21	6.51e-09	GO:0048522	positive regulation of cellular process
1.18	7.52e-09	GO:0060255	regulation of macromolecule metabolic process
1.11	7.99e-09	GO:0050794	regulation of cellular process
1.21	1.09e-08	GO:0044249	cellular biosynthetic process
1.26	2.02e-08	GO:0006996	organelle organization
1.36	2.46e-08	GO:0006351	transcription, DNA-dependent
1.20	2.52e-08	GO:0048518	positive regulation of biological process
1.22	3.09e-08	GO:0090304	nucleic acid metabolic process
1.15	4.01e-08	GO:0019222	regulation of metabolic process
1.20	4.78e-08	GO:0009058	biosynthetic process
1.16	6.36e-08	GO:0080090	regulation of primary metabolic process
1.24	1.53e-07	GO:0016070	RNA metabolic process
1.33	3.94e-07	GO:0010605	negative regulation of macromolecule metabolic process
1.20	5.21e-07	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.33	5.44e-07	GO:0031324	negative regulation of cellular metabolic process
1.18	6.08e-07	GO:0031326	regulation of cellular biosynthetic process
1.38	6.30e-07	GO:0009890	negative regulation of biosynthetic process
1.38	6.61e-07	GO:0031327	negative regulation of cellular biosynthetic process
1.09	7.63e-07	GO:0050789	regulation of biological process
1.19	9.95e-07	GO:0010556	regulation of macromolecule biosynthetic process
1.31	1.16e-06	GO:0009892	negative regulation of metabolic process
1.18	1.20e-06	GO:0009889	regulation of biosynthetic process
1.25	1.25e-06	GO:0007399	nervous system development
1.38	1.54e-06	GO:0010558	negative regulation of macromolecule biosynthetic process
1.31	1.80e-06	GO:0032774	RNA biosynthetic process
1.19	1.95e-06	GO:0044267	cellular protein metabolic process
1.09	2.12e-06	GO:0065007	biological regulation
1.39	2.89e-06	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.19	4.74e-06	GO:0051252	regulation of RNA metabolic process
1.21	5.07e-06	GO:0010467	gene expression
1.42	5.17e-06	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.26	9.25e-06	GO:0051641	cellular localization
1.17	1.10e-05	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36	1.20e-05	GO:0007167	enzyme linked receptor protein signaling pathway
1.22	1.29e-05	GO:0034645	cellular macromolecule biosynthetic process
1.33	1.31e-05	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38	1.33e-05	GO:0010629	negative regulation of gene expression
1.17	1.44e-05	GO:0010468	regulation of gene expression
1.21	1.47e-05	GO:0006464	protein modification process
1.33	1.89e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
1.35	1.99e-05	GO:0051254	positive regulation of RNA metabolic process
1.39	2.39e-05	GO:0051253	negative regulation of RNA metabolic process
1.16	2.51e-05	GO:0051171	regulation of nitrogen compound metabolic process
1.21	2.81e-05	GO:0009059	macromolecule biosynthetic process
1.60	3.43e-05	GO:0048011	nerve growth factor receptor signaling pathway
1.26	3.64e-05	GO:0031325	positive regulation of cellular metabolic process
1.36	3.83e-05	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26	4.01e-05	GO:0010604	positive regulation of macromolecule metabolic process
1.25	4.42e-05	GO:0009893	positive regulation of metabolic process
1.39	4.64e-05	GO:0045892	negative regulation of transcription, DNA-dependent
1.36	5.27e-05	GO:0051172	negative regulation of nitrogen compound metabolic process
1.18	1.11e-04	GO:0006355	regulation of transcription, DNA-dependent
1.22	1.12e-04	GO:0009653	anatomical structure morphogenesis
1.13	1.54e-04	GO:0051179	localization
1.19	1.75e-04	GO:0043412	macromolecule modification
1.22	2.22e-04	GO:0009966	regulation of signal transduction
1.25	2.70e-04	GO:0051649	establishment of localization in cell
1.26	3.08e-04	GO:0007049	cell cycle
1.20	3.81e-04	GO:0023051	regulation of signaling
1.14	5.27e-04	GO:0048856	anatomical structure development
1.28	6.97e-04	GO:0051128	regulation of cellular component organization
1.29	8.47e-04	GO:0046907	intracellular transport
1.32	8.67e-04	GO:0045893	positive regulation of transcription, DNA-dependent
1.32	9.59e-04	GO:0032989	cellular component morphogenesis
1.32	1.28e-03	GO:0051726	regulation of cell cycle
1.53	1.62e-03	GO:0045786	negative regulation of cell cycle
1.32	1.75e-03	GO:0000902	cell morphogenesis
1.43	1.75e-03	GO:0071495	cellular response to endogenous stimulus
1.37	1.77e-03	GO:0060548	negative regulation of cell death
1.52	2.17e-03	GO:0071375	cellular response to peptide hormone stimulus
1.16	2.17e-03	GO:0048869	cellular developmental process
1.24	2.95e-03	GO:0043067	regulation of programmed cell death
1.12	3.02e-03	GO:0032502	developmental process
1.24	3.12e-03	GO:0042981	regulation of apoptosis
1.26	3.35e-03	GO:0016265	death
1.26	4.06e-03	GO:0031328	positive regulation of cellular biosynthetic process
1.26	4.15e-03	GO:0008219	cell death
1.27	4.58e-03	GO:0016192	vesicle-mediated transport
1.23	4.68e-03	GO:0010941	regulation of cell death
1.13	4.71e-03	GO:0019538	protein metabolic process
1.56	4.82e-03	GO:0032869	cellular response to insulin stimulus
1.29	5.65e-03	GO:0010628	positive regulation of gene expression
1.26	5.98e-03	GO:0022402	cell cycle process
1.36	6.02e-03	GO:0032583	regulation of gene-specific transcription
1.37	6.70e-03	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.13	6.89e-03	GO:0051234	establishment of localization
1.26	7.36e-03	GO:0033554	cellular response to stress
1.13	7.39e-03	GO:0048731	system development
1.39	8.33e-03	GO:0016568	chromatin modification
1.67	9.49e-03	GO:0007265	Ras protein signal transduction
1.35	1.06e-02	GO:0043069	negative regulation of programmed cell death
1.47	1.09e-02	GO:0007507	heart development
1.25	1.10e-02	GO:0009891	positive regulation of biosynthetic process
1.33	1.15e-02	GO:0072358	cardiovascular system development
1.33	1.15e-02	GO:0072359	circulatory system development
1.13	1.18e-02	GO:0006810	transport
1.35	1.36e-02	GO:0043066	negative regulation of apoptosis
1.15	1.47e-02	GO:0030154	cell differentiation
1.41	1.76e-02	GO:0032870	cellular response to hormone stimulus
1.33	1.86e-02	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.26	1.99e-02	GO:0006915	apoptosis
1.41	2.22e-02	GO:0006366	transcription from RNA polymerase II promoter
1.22	2.29e-02	GO:0006793	phosphorus metabolic process
1.22	2.29e-02	GO:0006796	phosphate metabolic process
1.91	2.42e-02	GO:0061008	hepaticobiliary system development
1.26	2.54e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
1.31	2.57e-02	GO:0032990	cell part morphogenesis
1.48	2.68e-02	GO:0043193	positive regulation of gene-specific transcription
1.23	2.70e-02	GO:0022008	neurogenesis
1.11	3.26e-02	GO:0007275	multicellular organismal development
1.25	3.66e-02	GO:0012501	programmed cell death
1.21	3.82e-02	GO:0051246	regulation of protein metabolic process
1.26	3.86e-02	GO:0009790	embryo development
1.20	3.98e-02	GO:0044248	cellular catabolic process
1.36	4.07e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.35	4.57e-02	GO:0007264	small GTPase mediated signal transduction
1.89	4.65e-02	GO:0001889	liver development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.13	3.69e-50	GO:0005622	intracellular
1.13	5.75e-48	GO:0044424	intracellular part
1.14	2.28e-35	GO:0043226	organelle
1.14	1.26e-34	GO:0043229	intracellular organelle
1.15	2.88e-34	GO:0043227	membrane-bounded organelle
1.15	1.63e-33	GO:0043231	intracellular membrane-bounded organelle
1.15	2.96e-32	GO:0005737	cytoplasm
1.16	1.66e-18	GO:0044444	cytoplasmic part
1.17	2.05e-18	GO:0005634	nucleus
1.16	5.12e-18	GO:0044422	organelle part
1.16	9.53e-18	GO:0044446	intracellular organelle part
1.27	5.18e-12	GO:0031981	nuclear lumen
1.24	1.73e-11	GO:0070013	intracellular organelle lumen
1.23	2.60e-11	GO:0031974	membrane-enclosed lumen
1.24	2.63e-11	GO:0044428	nuclear part
1.23	3.35e-11	GO:0043233	organelle lumen
1.30	1.64e-10	GO:0005654	nucleoplasm
1.04	2.39e-10	GO:0044464	cell part
1.04	2.66e-10	GO:0005623	cell
1.23	1.45e-09	GO:0005829	cytosol
1.33	2.81e-06	GO:0044451	nucleoplasm part
1.18	8.85e-06	GO:0031090	organelle membrane
1.25	7.86e-05	GO:0005794	Golgi apparatus
1.28	7.74e-04	GO:0015630	microtubule cytoskeleton
1.13	8.50e-04	GO:0043234	protein complex
1.11	3.18e-03	GO:0032991	macromolecular complex
1.17	4.79e-03	GO:0012505	endomembrane system
1.28	1.04e-02	GO:0005694	chromosome
1.72	1.30e-02	GO:0000790	nuclear chromatin
1.47	1.88e-02	GO:0031252	cell leading edge
1.26	2.13e-02	GO:0044431	Golgi apparatus part
1.22	2.29e-02	GO:0031982	vesicle
1.80	3.57e-02	GO:0030496	midbody

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	2.36e-27	GO:0005515	protein binding
1.09	4.95e-24	GO:0005488	binding
1.33	7.43e-09	GO:0030528	transcription regulator activity
1.20	3.91e-08	GO:0000166	nucleotide binding
1.16	9.78e-08	GO:0003676	nucleic acid binding
1.18	1.71e-06	GO:0003677	DNA binding
1.32	1.40e-05	GO:0019899	enzyme binding
1.26	5.56e-05	GO:0001071	nucleic acid binding transcription factor activity
1.26	5.56e-05	GO:0003700	sequence-specific DNA binding transcription factor activity
1.18	5.75e-05	GO:0032553	ribonucleotide binding
1.18	5.75e-05	GO:0032555	purine ribonucleotide binding
1.18	7.59e-05	GO:0035639	purine ribonucleoside triphosphate binding
1.18	8.76e-05	GO:0017076	purine nucleotide binding
1.20	9.11e-05	GO:0032559	adenyl ribonucleotide binding
1.10	1.04e-04	GO:0003824	catalytic activity
1.20	1.17e-04	GO:0030554	adenyl nucleotide binding
1.47	1.85e-04	GO:0008134	transcription factor binding
1.20	1.87e-04	GO:0005524	ATP binding
1.43	8.43e-04	GO:0016564	transcription repressor activity
1.62	1.09e-03	GO:0003714	transcription corepressor activity
1.17	1.63e-03	GO:0016740	transferase activity
1.35	2.00e-03	GO:0019904	protein domain specific binding
1.52	2.20e-03	GO:0010843	promoter binding
1.24	2.23e-03	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.37	2.28e-03	GO:0000988	protein binding transcription factor activity
1.37	2.28e-03	GO:0000989	transcription factor binding transcription factor activity
1.37	3.16e-03	GO:0003712	transcription cofactor activity
1.26	4.53e-03	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.49	4.97e-03	GO:0000975	regulatory region DNA binding
1.49	4.97e-03	GO:0001067	regulatory region nucleic acid binding
1.49	4.97e-03	GO:0044212	transcription regulatory region DNA binding
1.24	7.23e-03	GO:0016301	kinase activity
1.38	8.50e-03	GO:0016563	transcription activator activity
1.26	8.81e-03	GO:0043565	sequence-specific DNA binding
1.41	8.95e-03	GO:0016881	acid-amino acid ligase activity
1.38	1.61e-02	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.26	1.68e-02	GO:0004672	protein kinase activity
1.31	2.65e-02	GO:0004674	protein serine/threonine kinase activity
1.43	3.06e-02	GO:0004842	ubiquitin-protein ligase activity
1.41	3.06e-02	GO:0019787	small conjugating protein ligase activity
1.44	4.56e-02	GO:0019901	protein kinase binding