Motif ID: TFCP2.p2

Z-value: 1.682


Transcription factors associated with TFCP2.p2:

Gene SymbolEntrez IDGene Name
TFCP2 7024 transcription factor CP2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
TFCP2chr12_-_51566555-0.601.6e-03Click!


Activity profile for motif TFCP2.p2.

activity profile for motif TFCP2.p2


Sorted Z-values histogram for motif TFCP2.p2

Sorted Z-values for motif TFCP2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFCP2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_31550065 9.891 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr8_+_17354562 5.963 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr5_+_127419407 4.962 NM_001046
SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr1_-_41328019 4.410 CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr7_-_98741681 3.525 NM_001199847
NM_020429
NM_181349
SMURF1


SMAD specific E3 ubiquitin protein ligase 1


chr17_+_21188021 3.192 MAP2K3
mitogen-activated protein kinase kinase 3
chr17_+_74380676 3.167 NM_001142601
NM_021972
NM_182965
SPHK1


sphingosine kinase 1


chr7_-_98741375 3.006 SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr10_+_104155431 2.965 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr6_-_44233244 2.802 NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr17_+_21188032 2.792 MAP2K3
mitogen-activated protein kinase kinase 3
chr17_+_21187967 2.782 NM_145109
MAP2K3
mitogen-activated protein kinase kinase 3
chr1_-_41328002 2.715 NM_133467
CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr5_+_179234002 2.703 NM_001142299
SQSTM1
sequestosome 1
chr7_-_98741605 2.647 SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr6_-_44233499 2.592 NM_004556
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr19_-_4338750 2.543 NM_001013841
NM_017720
STAP2

signal transducing adaptor family member 2

chr9_+_116930778 2.536 COL27A1
collagen, type XXVII, alpha 1
chr1_-_33430285 2.533 NM_001127361
NM_153341
RNF19B

ring finger protein 19B

chr11_-_4414887 2.378 NM_003141
TRIM21
tripartite motif containing 21

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 62 entries
enrichment   p-value GO term description
3.36 2.14e-02 GO:0045930 negative regulation of mitotic cell cycle
2.03 5.10e-03 GO:0045792 negative regulation of cell size
1.99 3.62e-02 GO:0045927 positive regulation of growth
1.96 3.96e-02 GO:0030308 negative regulation of cell growth
1.79 2.88e-04 GO:0001558 regulation of cell growth
1.78 1.73e-04 GO:0008361 regulation of cell size
1.74 1.16e-05 GO:0032535 regulation of cellular component size
1.70 1.22e-05 GO:0090066 regulation of anatomical structure size
1.61 1.99e-02 GO:0051960 regulation of nervous system development
1.59 1.25e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.58 1.39e-02 GO:0060284 regulation of cell development
1.57 8.22e-04 GO:0008285 negative regulation of cell proliferation
1.52 1.55e-02 GO:0007264 small GTPase mediated signal transduction
1.51 9.79e-06 GO:0030182 neuron differentiation
1.51 9.21e-03 GO:0040008 regulation of growth
1.49 1.46e-02 GO:0051094 positive regulation of developmental process
1.48 3.20e-02 GO:0007409 axonogenesis
1.47 2.40e-02 GO:0060548 negative regulation of cell death
1.45 2.90e-05 GO:0051128 regulation of cellular component organization
1.45 5.90e-03 GO:0048666 neuron development

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.20 2.80e-03 GO:0005829 cytosol
1.11 5.69e-08 GO:0005737 cytoplasm
1.06 4.31e-04 GO:0005622 intracellular
1.05 3.73e-03 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.73 2.69e-02 GO:0005085 guanyl-nucleotide exchange factor activity
1.54 2.13e-02 GO:0005083 small GTPase regulator activity
1.52 2.53e-04 GO:0030695 GTPase regulator activity
1.51 4.02e-04 GO:0060589 nucleoside-triphosphatase regulator activity
1.36 1.43e-02 GO:0043565 sequence-specific DNA binding
1.29 1.43e-02 GO:0030528 transcription regulator activity
1.14 1.92e-10 GO:0005515 protein binding
1.05 1.01e-02 GO:0005488 binding