Motif ID: TFEB.p2

Z-value: 1.100


Transcription factors associated with TFEB.p2:

Gene SymbolEntrez IDGene Name
TFEB 7942 transcription factor EB

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
TFEBchr6_-_41702734,
chr6_-_41703938		0.301.5e-01Click!


Activity profile for motif TFEB.p2.

activity profile for motif TFEB.p2


Sorted Z-values histogram for motif TFEB.p2

Sorted Z-values for motif TFEB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFEB.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_11866079 7.361 NM_005957
 MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr7_-_27183225 4.889 NM_019102
 HOXA5
homeobox A5
chrX_+_101975641 4.289 NM_001142524
NM_001142525
NM_001142526
NM_001142527
NM_001142528
NM_030639
 BHLHB9





basic helix-loop-helix domain containing, class B, 9





chr17_-_46688362 3.852 NM_004502
 HOXB7
homeobox B7
chr6_+_87865261 3.835 NM_015021
 ZNF292
zinc finger protein 292
chr19_-_36545119 3.650 THAP8
THAP domain containing 8
chr20_-_39317875 3.617 NM_005461
 MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr11_+_67159421 3.521 NM_004584
 RAD9A
RAD9 homolog A (S. pombe)
chr10_-_105452878 3.467 SH3PXD2A
SH3 and PX domains 2A
chr11_+_7535213 3.426 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr17_-_47841517 3.337 NM_030802
 FAM117A
family with sequence similarity 117, member A
chr3_-_122512526 3.254 NM_024610
 HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr5_-_172198160 3.232 NM_004417
 DUSP1
dual specificity phosphatase 1
chr17_-_46688279 3.195 HOXB7
homeobox B7
chr1_-_11865963 3.120 MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr16_+_30960377 3.081 NM_152288
 ORAI3
ORAI calcium release-activated calcium modulator 3
chr17_+_47866061 2.997 KAT7
K(lysine) acetyltransferase 7
chr7_-_27196163 2.985 NM_006896
 HOXA7
homeobox A7
chr16_+_30960413 2.981 ORAI3
ORAI calcium release-activated calcium modulator 3
chr17_+_47865980 2.980 NM_001199155
NM_001199156
NM_001199157
NM_001199158
NM_007067
 KAT7




K(lysine) acetyltransferase 7





Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
20.90 1.01e-02 GO:0021569 rhombomere 3 development
14.93 9.35e-03 GO:0021546 rhombomere development
7.74 4.69e-04 GO:0007040 lysosome organization
6.97 6.91e-07 GO:0007033 vacuole organization
4.69 5.27e-03 GO:0048704 embryonic skeletal system morphogenesis
3.97 8.40e-03 GO:0048706 embryonic skeletal system development
3.18 1.49e-02 GO:0048705 skeletal system morphogenesis
2.45 4.64e-02 GO:0003002 regionalization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
3.33 3.43e-11 GO:0005773 vacuole
3.28 5.53e-09 GO:0000323 lytic vacuole
3.28 5.53e-09 GO:0005764 lysosome
3.22 1.32e-04 GO:0044437 vacuolar part
3.12 9.60e-03 GO:0005765 lysosomal membrane
3.09 8.04e-04 GO:0005774 vacuolar membrane
3.04 1.35e-02 GO:0005770 late endosome
2.29 1.86e-02 GO:0010008 endosome membrane
2.27 2.13e-02 GO:0044440 endosomal part
1.55 6.07e-03 GO:0005654 nucleoplasm
1.23 8.13e-04 GO:0044444 cytoplasmic part
1.23 3.75e-03 GO:0044446 intracellular organelle part
1.22 6.79e-03 GO:0044422 organelle part
1.18 1.21e-04 GO:0043231 intracellular membrane-bounded organelle
1.18 1.42e-04 GO:0043227 membrane-bounded organelle
1.16 1.74e-04 GO:0043229 intracellular organelle
1.15 2.29e-04 GO:0043226 organelle
1.15 1.84e-02 GO:0005737 cytoplasm
1.13 7.75e-05 GO:0044424 intracellular part
1.12 9.18e-05 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
3.01 3.31e-02 GO:0016798 hydrolase activity, acting on glycosyl bonds