Motif ID: TLX2.p2

Z-value: 1.512


Transcription factors associated with TLX2.p2:

Gene SymbolEntrez IDGene Name
TLX2 3196 T-cell leukemia homeobox 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
TLX2chr2_+_74740585-0.311.3e-01Click!


Activity profile for motif TLX2.p2.

activity profile for motif TLX2.p2


Sorted Z-values histogram for motif TLX2.p2

Sorted Z-values for motif TLX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_31550065 8.497 NM_002341
NM_009588
 LTB

lymphotoxin beta (TNF superfamily, member 3)

chr16_+_57406398 8.395 NM_002996
 CX3CL1
chemokine (C-X3-C motif) ligand 1
chr2_+_102979096 8.219 NM_003855
 IL18R1
interleukin 18 receptor 1
chr1_-_169703178 6.358 NM_000450
 SELE
selectin E
chr5_+_131409484 5.112 NM_000758
 CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr14_+_55034633 5.055 SAMD4A
sterile alpha motif domain containing 4A
chr6_-_143266283 4.616 NM_006734
 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr2_+_228678556 4.307 NM_001130046
NM_004591
 CCL20

chemokine (C-C motif) ligand 20

chr19_+_676346 4.045 NM_005860
 FSTL3
follistatin-like 3 (secreted glycoprotein)
chr21_+_43639202 3.895 NM_004915
NM_016818
 ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr7_+_28448970 3.771 LOC401317
uncharacterized LOC401317
chr6_-_29527477 3.635 UBD
ubiquitin D
chr1_+_101185195 3.308 NM_001078
NM_001199834
NM_080682
 VCAM1


vascular cell adhesion molecule 1


chr1_-_95007139 3.143 NM_001178096
NM_001993
 F3

coagulation factor III (thromboplastin, tissue factor)

chrX_+_117480416 3.048 WDR44
WD repeat domain 44
chr6_-_29527701 2.916 NM_006398
 UBD
ubiquitin D
chr16_-_11680756 2.904 NM_001136472
NM_001136473
 LITAF

lipopolysaccharide-induced TNF factor

chr2_+_150187028 2.758 NM_194317
 LYPD6
LY6/PLAUR domain containing 6
chr3_-_107809754 2.625 NM_001777
NM_198793
 CD47

CD47 molecule

chr11_-_128457452 2.546 NM_001143820
 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
1.69 2.25e-04 GO:0006915 apoptosis
1.68 2.60e-04 GO:0012501 programmed cell death
1.67 3.59e-02 GO:0007599 hemostasis
1.65 1.70e-02 GO:0050878 regulation of body fluid levels
1.57 1.65e-03 GO:0008219 cell death
1.57 2.14e-03 GO:0016265 death
1.47 1.70e-03 GO:0002376 immune system process
1.41 2.79e-02 GO:0009893 positive regulation of metabolic process
1.34 4.72e-05 GO:0048518 positive regulation of biological process
1.31 3.86e-03 GO:0048522 positive regulation of cellular process
1.25 1.64e-02 GO:0048856 anatomical structure development
1.22 3.91e-02 GO:0007275 multicellular organismal development
1.21 2.93e-02 GO:0032502 developmental process
1.16 1.33e-04 GO:0065007 biological regulation
1.16 3.80e-04 GO:0050789 regulation of biological process
1.09 8.50e-03 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.42 1.27e-03 GO:0031226 intrinsic to plasma membrane
1.41 2.51e-03 GO:0005887 integral to plasma membrane
1.38 8.18e-06 GO:0044459 plasma membrane part
1.30 5.41e-03 GO:0005829 cytosol
1.21 1.17e-03 GO:0005886 plasma membrane
1.21 1.40e-03 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.48 1.67e-03 GO:0005102 receptor binding
1.18 1.31e-06 GO:0005515 protein binding
1.07 9.69e-03 GO:0005488 binding