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Motif ID: TLX2.p2

Z-value: 1.512

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_-_31550065	8.497	NM_002341 NM_009588	LTB	lymphotoxin beta (TNF superfamily, member 3)
chr16_+_57406398	8.395	NM_002996	CX3CL1	chemokine (C-X3-C motif) ligand 1
chr2_+_102979096	8.219	NM_003855	IL18R1	interleukin 18 receptor 1
chr1_-_169703178	6.358	NM_000450	SELE	selectin E
chr5_+_131409484	5.112	NM_000758	CSF2	colony stimulating factor 2 (granulocyte-macrophage)
chr14_+_55034633	5.055		SAMD4A	sterile alpha motif domain containing 4A
chr6_-_143266283	4.616	NM_006734	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2
chr2_+_228678556	4.307	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr19_+_676346	4.045	NM_005860	FSTL3	follistatin-like 3 (secreted glycoprotein)
chr21_+_43639202	3.895	NM_004915 NM_016818	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr7_+_28448970	3.771		LOC401317	uncharacterized LOC401317
chr6_-_29527477	3.635		UBD	ubiquitin D
chr1_+_101185195	3.308	NM_001078 NM_001199834 NM_080682	VCAM1	vascular cell adhesion molecule 1
chr1_-_95007139	3.143	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chrX_+_117480416	3.048		WDR44	WD repeat domain 44
chr6_-_29527701	2.916	NM_006398	UBD	ubiquitin D
chr16_-_11680756	2.904	NM_001136472 NM_001136473	LITAF	lipopolysaccharide-induced TNF factor
chr2_+_150187028	2.758	NM_194317	LYPD6	LY6/PLAUR domain containing 6
chr3_-_107809754	2.625	NM_001777 NM_198793	CD47	CD47 molecule
chr11_-_128457452	2.546	NM_001143820	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr10_+_104154228	2.502	NM_001077493 NM_001077494	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr7_-_22396511	2.272	NM_012294	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5
chr5_+_125759076	2.183		GRAMD3	GRAM domain containing 3
chr11_+_19372270	2.159	NM_001111018	NAV2	neuron navigator 2
chr14_+_103589711	2.143		TNFAIP2	tumor necrosis factor, alpha-induced protein 2
chr6_+_26440699	1.988	NM_001242803 NM_006994 NM_197974	BTN3A3	butyrophilin, subfamily 3, member A3
chr3_-_182880463	1.959	NM_014398	LAMP3	lysosomal-associated membrane protein 3
chr21_-_37948866	1.955	NM_001146077	CLDN14	claudin 14
chr3_+_5021305	1.953		BHLHE40	basic helix-loop-helix family, member e40
chr12_+_100660846	1.943		SCYL2	SCY1-like 2 (S. cerevisiae)
chr21_-_38639593	1.897		DSCR3	Down syndrome critical region gene 3
chr21_+_35736322	1.844	NM_172201	KCNE2	potassium voltage-gated channel, Isk-related family, member 2
chr2_+_219433517	1.826	NM_005444	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr7_+_28475233	1.811	NM_004904	CREB5	cAMP responsive element binding protein 5
chr1_+_169075869	1.791	NM_001677	ATP1B1	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr22_+_41697452	1.784	NM_017590	ZC3H7B	zinc finger CCCH-type containing 7B
chr20_+_44746889	1.745	NM_001250 NM_152854	CD40	CD40 molecule, TNF receptor superfamily member 5
chr4_+_156680603	1.653		GUCY1B3	guanylate cyclase 1, soluble, beta 3
chr5_-_150466696	1.629	NM_001252391 NM_001252392	TNIP1	TNFAIP3 interacting protein 1
chr20_+_44746948	1.606		CD40	CD40 molecule, TNF receptor superfamily member 5
chr14_-_53417272	1.606		FERMT2	fermitin family member 2
chr17_+_25958245	1.601		LGALS9	lectin, galactoside-binding, soluble, 9
chr10_-_60027630	1.566	NM_152230	IPMK	inositol polyphosphate multikinase
chr14_+_55034329	1.558	NM_001161576 NM_015589	SAMD4A	sterile alpha motif domain containing 4A
chr17_+_25958257	1.555		LGALS9	lectin, galactoside-binding, soluble, 9
chr10_+_73555527	1.532	NM_001171933 NM_001171934	CDH23	cadherin-related 23
chr1_-_117113593	1.532		CD58	CD58 molecule
chr15_-_50411405	1.493	NM_024837	ATP8B4	ATPase, class I, type 8B, member 4
chr6_+_37137882	1.485	NM_001243186 NM_002648	PIM1	pim-1 oncogene
chr3_-_78666943	1.476		ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr2_-_175869910	1.460	NM_001822 NM_001025201	CHN1	chimerin (chimaerin) 1
chr8_-_105601124	1.452		LRP12	low density lipoprotein receptor-related protein 12
chr13_+_26828755	1.450	NM_001260	CDK8	cyclin-dependent kinase 8
chr11_-_128391888	1.441		ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr17_+_41158741	1.431	NM_005533	IFI35	interferon-induced protein 35
chr6_+_160148145	1.426	NM_004906 NM_152858	WTAP	Wilms tumor 1 associated protein
chr4_-_139163222	1.407	NM_014331	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr2_-_204399906	1.404	NM_203365 NM_213589	RAPH1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr11_-_128392061	1.392	NM_001162422 NM_005238	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr12_-_51422012	1.392	NM_001174125	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr18_+_55862577	1.379	NM_001144970	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr1_-_117113640	1.367	NM_001144822 NM_001779	CD58	CD58 molecule
chr8_+_120428551	1.363	NM_002514	NOV	nephroblastoma overexpressed gene
chr21_-_16437125	1.357	NM_003489	NRIP1	nuclear receptor interacting protein 1
chr5_-_179780314	1.335	NM_005110	GFPT2	glutamine-fructose-6-phosphate transaminase 2
chr8_-_105601234	1.325	NM_001135703 NM_013437	LRP12	low density lipoprotein receptor-related protein 12
chr3_+_151986731	1.321		MBNL1	muscleblind-like (Drosophila)
chr1_+_110453456	1.304		CSF1	colony stimulating factor 1 (macrophage)
chr4_+_156680125	1.299	NM_000857	GUCY1B3	guanylate cyclase 1, soluble, beta 3
chr3_+_11196213	1.263	NM_001098212	HRH1	histamine receptor H1
chr3_+_112051914	1.260	NM_001004196 NM_005944	CD200	CD200 molecule
chr10_+_115439632	1.248		CASP7	caspase 7, apoptosis-related cysteine peptidase
chr10_+_96305521	1.230	NM_018063	HELLS	helicase, lymphoid-specific
chr2_+_111878450	1.183	NM_001204106 NM_001204107 NM_001204108 NM_001204109 NM_001204110 NM_001204111 NM_001204112 NM_001204113 NM_006538 NM_138621 NM_138622 NM_138623 NM_138624 NM_138625 NM_138626 NM_138627 NM_207002 NM_207003	BCL2L11	BCL2-like 11 (apoptosis facilitator)
chr2_+_223725675	1.178	NM_004457 NM_203372	ACSL3	acyl-CoA synthetase long-chain family member 3
chr5_+_125695787	1.174	NM_001146319	GRAMD3	GRAM domain containing 3
chr19_+_45251933	1.172	NM_005178	BCL3	B-cell CLL/lymphoma 3
chr8_-_119964059	1.168	NM_002546	TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b
chr17_-_79829237	1.157		ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha
chr8_-_104427319	1.148		SLC25A32	solute carrier family 25, member 32
chr17_+_25958151	1.145	NM_002308 NM_009587	LGALS9	lectin, galactoside-binding, soluble, 9
chr1_-_230991781	1.141	NM_001136495	C1orf198	chromosome 1 open reading frame 198
chr8_+_41435666	1.131	NM_178819	AGPAT6	1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)
chr5_+_130599745	1.127		CDC42SE2	CDC42 small effector 2
chr22_+_31644314	1.126	NM_001031801 NM_016733	LIMK2	LIM domain kinase 2
chr18_+_49867069	1.125		DCC	deleted in colorectal carcinoma
chr6_-_31324955	1.125		HLA-B	major histocompatibility complex, class I, B
chr17_+_25958192	1.124		LGALS9	lectin, galactoside-binding, soluble, 9
chr4_-_122148620	1.123	NM_001244764	TNIP3	TNFAIP3 interacting protein 3
chr12_-_57505121	1.119		STAT6	signal transducer and activator of transcription 6, interleukin-4 induced
chr8_-_104427268	1.113		SLC25A32	solute carrier family 25, member 32
chr6_-_31324898	1.111		HLA-B	major histocompatibility complex, class I, B
chr6_-_33281790	1.103		TAPBP	TAP binding protein (tapasin)
chr17_-_79829272	1.098	NM_001185078 NM_004309	ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha
chrX_+_70765479	1.089		OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr3_-_112693711	1.089	NM_138806 NM_138939 NM_138940 NM_170780	CD200R1	CD200 receptor 1
chr6_-_33281847	1.081		TAPBP	TAP binding protein (tapasin)
chr19_+_44080951	1.077	NM_001193621	LOC390940	uncharacterized protein ENSP00000244321
chr5_-_150080546	1.065		RBM22	RNA binding motif protein 22
chr10_-_121632265	1.050	NM_024834	MCMBP	minichromosome maintenance complex binding protein
chr3_+_133292404	1.046	NM_001134422 NM_017548	CDV3	CDV3 homolog (mouse)
chr6_-_31324975	1.043	NM_005514	HLA-B	major histocompatibility complex, class I, B
chr6_+_158438079	1.042	NM_001178088	SYNJ2	synaptojanin 2
chr6_+_106546736	1.036	NM_182907	PRDM1	PR domain containing 1, with ZNF domain
chr5_-_126366068	1.035		MARCH3	membrane-associated ring finger (C3HC4) 3
chr4_-_146095891	1.034	NM_017493	OTUD4	OTU domain containing 4
chr7_+_134331530	1.018	NM_001724 NM_199186	BPGM	2,3-bisphosphoglycerate mutase
chr17_-_79829174	1.015		ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha
chr3_+_112052020	1.014		CD200	CD200 molecule
chr6_+_26365397	1.013	NM_001197247 NM_001197249 NM_007047 NM_001197248	BTN3A2	butyrophilin, subfamily 3, member A2
chr6_+_158402916	1.003		SYNJ2	synaptojanin 2
chr5_+_133984234	1.002	NM_001252231 NM_021982	SEC24A	SEC24 family, member A (S. cerevisiae)
chr8_-_104427373	1.000	NM_030780	SLC25A32	solute carrier family 25, member 32
chr10_+_73571639	0.998	NM_001171935 NM_001171936	CDH23	cadherin-related 23
chr1_-_33336289	0.995	NM_001171940 NM_153756	FNDC5	fibronectin type III domain containing 5
chr12_-_57505176	0.991	NM_001178078 NM_001178080 NM_001178081 NM_003153	STAT6	signal transducer and activator of transcription 6, interleukin-4 induced
chr9_+_126118447	0.991	NM_173689	CRB2	crumbs homolog 2 (Drosophila)
chr10_+_75670861	0.989	NM_001145031 NM_002658	PLAU	plasminogen activator, urokinase
chr4_-_7436614	0.987	NM_001085382	PSAPL1	prosaposin-like 1 (gene/pseudogene)
chr1_+_16174358	0.986	NM_015001	SPEN	spen homolog, transcriptional regulator (Drosophila)
chr1_+_114472438	0.979		HIPK1	homeodomain interacting protein kinase 1
chr9_-_73029539	0.979	NM_001206	KLF9	Kruppel-like factor 9
chr11_-_72380107	0.979	NM_001146209	PDE2A	phosphodiesterase 2A, cGMP-stimulated
chr5_+_133451297	0.978	NM_001134851 NM_201632 NM_201634 NM_213648	TCF7	transcription factor 7 (T-cell specific, HMG-box)
chr1_-_244006471	0.964	NM_005465 NM_181690	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
chr5_-_147162251	0.949	NM_014790	JAKMIP2	janus kinase and microtubule interacting protein 2
chr11_+_61957687	0.943	NM_006552	SCGB1D1	secretoglobin, family 1D, member 1
chr11_-_57089670	0.940		TNKS1BP1	tankyrase 1 binding protein 1, 182kDa
chr3_+_5021141	0.937		BHLHE40	basic helix-loop-helix family, member e40
chrX_+_15518899	0.935	NM_203281	BMX	BMX non-receptor tyrosine kinase
chr10_+_75673346	0.934		PLAU	plasminogen activator, urokinase
chr6_-_11382501	0.930	NM_001142393	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr7_+_45197366	0.927	NM_005856	RAMP3	receptor (G protein-coupled) activity modifying protein 3
chr1_+_24286311	0.922		PNRC2	proline-rich nuclear receptor coactivator 2
chr3_+_113465901	0.899		ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr19_+_7030593	0.896	NM_001136507	MBD3L5	methyl-CpG binding domain protein 3-like 5
chr12_-_48499840	0.892		SENP1	SUMO1/sentrin specific peptidase 1
chr5_-_147162175	0.891		JAKMIP2	janus kinase and microtubule interacting protein 2
chr15_+_85666291	0.882		PDE8A	phosphodiesterase 8A
chr5_+_177540465	0.881	NM_015111	N4BP3	NEDD4 binding protein 3
chr7_+_100728719	0.878	NM_030961	TRIM56	tripartite motif containing 56
chr5_+_149865310	0.877		NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr20_-_61557818	0.870		DIDO1	death inducer-obliterator 1
chr1_+_218518675	0.868	NM_001135599 NM_003238	TGFB2	transforming growth factor, beta 2
chr6_+_158402887	0.865	NM_003898	SYNJ2	synaptojanin 2
chr15_-_38856830	0.865	NM_001128602 NM_005739	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr12_-_51740422	0.865	NM_001971	CELA1	chymotrypsin-like elastase family, member 1
chr17_-_76719645	0.864		CYTH1	cytohesin 1
chr17_-_76719671	0.857		CYTH1	cytohesin 1
chr15_+_45927217	0.851	NM_021199	SQRDL	sulfide quinone reductase-like (yeast)
chr1_-_65431826	0.851	NM_002227	JAK1	Janus kinase 1
chr13_+_111138079	0.845		COL4A2	collagen, type IV, alpha 2
chr17_-_1090562	0.845	NM_001159746	ABR	active BCR-related gene
chr20_-_1373571	0.843		FKBP1A	FK506 binding protein 1A, 12kDa
chr1_-_27930360	0.837		AHDC1	AT hook, DNA binding motif, containing 1
chr7_-_92465876	0.836		CDK6	cyclin-dependent kinase 6
chr22_-_22221937	0.836		MAPK1	mitogen-activated protein kinase 1
chr13_-_30169584	0.835		SLC7A1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr3_-_21792815	0.835	NM_024697	ZNF385D	zinc finger protein 385D
chr1_-_161279724	0.835	NM_000530	MPZ	myelin protein zero
chr1_-_21113147	0.834		HP1BP3	heterochromatin protein 1, binding protein 3
chr1_-_86043932	0.833	NM_001134445	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr19_+_48828820	0.826		EMP3	epithelial membrane protein 3
chr5_-_54830369	0.824	NM_003711 NM_176895	RNF138P1 PPAP2A	ring finger protein 138 pseudogene 1 phosphatidic acid phosphatase type 2A
chr19_-_55658310	0.821		TNNT1	troponin T type 1 (skeletal, slow)
chr14_+_70078313	0.820		KIAA0247	KIAA0247
chr19_+_36236460	0.818	NM_172341	PSENEN	presenilin enhancer 2 homolog (C. elegans)
chr18_+_55711890	0.813		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr19_+_51728369	0.808		CD33	CD33 molecule
chr7_+_31726630	0.803	NM_001145123 NM_006658	PPP1R17	protein phosphatase 1, regulatory subunit 17
chr4_+_169552752	0.799	NM_001166109	PALLD	palladin, cytoskeletal associated protein
chr2_+_108994366	0.796	NM_006588	SULT1C4	sulfotransferase family, cytosolic, 1C, member 4
chr10_+_111765725	0.794	NM_019903	ADD3	adducin 3 (gamma)
chr10_-_88281486	0.792		WAPAL	wings apart-like homolog (Drosophila)
chr2_+_64681610	0.788		LGALSL	lectin, galactoside-binding-like
chr20_+_46130656	0.779		NCOA3	nuclear receptor coactivator 3
chr6_-_35696359	0.778	NM_001145775	FKBP5	FK506 binding protein 5
chr19_+_41509825	0.765		CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6
chr19_-_3969734	0.759	NM_001348	DAPK3	death-associated protein kinase 3
chr10_+_75670915	0.758		PLAU	plasminogen activator, urokinase
chr7_+_48128939	0.753		UPP1	uridine phosphorylase 1
chr2_-_113522167	0.752	NM_152515	CKAP2L	cytoskeleton associated protein 2-like
chr1_+_36690038	0.749		THRAP3	thyroid hormone receptor associated protein 3
chr12_+_50794591	0.748	NM_001170803 NM_001170804 NM_001170808 NM_052879 NM_199188 NM_199190	LARP4	La ribonucleoprotein domain family, member 4
chr2_-_153573858	0.744	NM_017892	PRPF40A	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr11_+_64009587	0.742	NM_057092	FKBP2	FK506 binding protein 2, 13kDa
chr21_+_27012067	0.738		JAM2	junctional adhesion molecule 2
chr5_+_96271345	0.732	NM_005575	LNPEP	leucyl/cystinyl aminopeptidase
chr7_-_131241321	0.728	NM_001018111 NM_005397	PODXL	podocalyxin-like
chr17_-_42144986	0.724	NM_152344	LSM12	LSM12 homolog (S. cerevisiae)
chr2_+_61108702	0.719		REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr11_+_113775517	0.719	NM_006028	HTR3B	5-hydroxytryptamine (serotonin) receptor 3B
chr3_+_38537846	0.717		EXOG	endo/exonuclease (5'-3'), endonuclease G-like
chr14_-_21737506	0.711	NM_001077442 NM_001077443 NM_004500 NM_031314	HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr16_+_2039945	0.710	NM_004209	SYNGR3	synaptogyrin 3
chr2_+_208394823	0.709		CREB1	cAMP responsive element binding protein 1
chr16_+_56642477	0.709	NM_005953	MT2A	metallothionein 2A
chr12_+_117348710	0.708	NM_012174 NM_153348	FBXW8	F-box and WD repeat domain containing 8
chr20_-_1373744	0.707	NM_000801 NM_001199786 NM_054014	FKBP1A	FK506 binding protein 1A, 12kDa
chr10_-_74114655	0.706		DNAJB12	DnaJ (Hsp40) homolog, subfamily B, member 12

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.34	4.72e-05	GO:0048518	positive regulation of biological process
1.16	1.33e-04	GO:0065007	biological regulation
1.69	2.25e-04	GO:0006915	apoptosis
1.68	2.60e-04	GO:0012501	programmed cell death
1.16	3.80e-04	GO:0050789	regulation of biological process
1.57	1.65e-03	GO:0008219	cell death
1.47	1.70e-03	GO:0002376	immune system process
1.57	2.14e-03	GO:0016265	death
1.31	3.86e-03	GO:0048522	positive regulation of cellular process
1.09	8.50e-03	GO:0009987	cellular process
1.25	1.64e-02	GO:0048856	anatomical structure development
1.65	1.70e-02	GO:0050878	regulation of body fluid levels
1.41	2.79e-02	GO:0009893	positive regulation of metabolic process
1.21	2.93e-02	GO:0032502	developmental process
1.67	3.59e-02	GO:0007599	hemostasis
1.22	3.91e-02	GO:0007275	multicellular organismal development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.38	8.18e-06	GO:0044459	plasma membrane part
1.21	1.17e-03	GO:0005886	plasma membrane
1.42	1.27e-03	GO:0031226	intrinsic to plasma membrane
1.21	1.40e-03	GO:0071944	cell periphery
1.41	2.51e-03	GO:0005887	integral to plasma membrane
1.30	5.41e-03	GO:0005829	cytosol

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.18	1.31e-06	GO:0005515	protein binding
1.48	1.67e-03	GO:0005102	receptor binding
1.07	9.69e-03	GO:0005488	binding