Motif ID: UCACAGU

Z-value: 0.896


Mature miRNA associated with seed UCACAGU:

NamemiRBase Accession
hsa-miR-27a MIMAT0000084
hsa-miR-27b MIMAT0000419



Activity profile for motif UCACAGU.

activity profile for motif UCACAGU


Sorted Z-values histogram for motif UCACAGU

Sorted Z-values for motif UCACAGU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCACAGU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_92371558 3.507 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr1_-_92351613 3.368 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr1_+_61542928 2.952 NM_001145511
NFIA
nuclear factor I/A
chr2_+_7057471 2.890 NM_014746
RNF144A
ring finger protein 144A
chr19_+_39897457 2.838 NM_003407
ZFP36
zinc finger protein 36, C3H type, homolog (mouse)
chr1_+_61547625 2.824 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr6_-_13408368 2.814 NM_001242630
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr10_-_131762017 2.728 NM_001005463
EBF3
early B-cell factor 3
chr6_+_142622797 2.668 NM_001032394
NM_001032395
NM_020455
NM_198569
GPR126



G protein-coupled receptor 126



chr1_+_61547388 2.605 NM_001145512
NFIA
nuclear factor I/A
chr10_-_81205091 2.400 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr9_-_107690526 2.313 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr9_-_134151905 2.233 NM_033387
FAM78A
family with sequence similarity 78, member A
chr9_-_14398981 2.175 NM_001190738
NFIB
nuclear factor I/B
chr1_-_154474524 2.163 NM_001010846
SHE
Src homology 2 domain containing E
chr8_-_127570710 2.054 NM_174911
FAM84B
family with sequence similarity 84, member B
chr1_+_203274646 2.003 NM_006763
BTG2
BTG family, member 2
chr9_-_14314036 1.982 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr14_+_56584854 1.891 NM_021255
PELI2
pellino homolog 2 (Drosophila)
chr7_-_27183225 1.866 NM_019102
HOXA5
homeobox A5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
8.74 1.61e-02 GO:0018210 peptidyl-threonine modification
5.04 4.32e-02 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
2.50 1.66e-02 GO:0018193 peptidyl-amino acid modification
2.13 3.30e-02 GO:0045892 negative regulation of transcription, DNA-dependent
2.06 3.43e-02 GO:0010629 negative regulation of gene expression
2.04 3.29e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.00 4.16e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.67 1.15e-02 GO:0007399 nervous system development
1.63 2.95e-02 GO:0009653 anatomical structure morphogenesis
1.60 6.88e-03 GO:0006464 protein modification process
1.57 1.10e-02 GO:0043412 macromolecule modification
1.48 1.81e-02 GO:0048522 positive regulation of cellular process
1.47 1.01e-02 GO:0048518 positive regulation of biological process
1.39 1.43e-02 GO:0031323 regulation of cellular metabolic process
1.38 1.04e-02 GO:0032502 developmental process
1.36 1.35e-02 GO:0019222 regulation of metabolic process
1.36 2.77e-02 GO:0023052 signaling
1.29 8.09e-05 GO:0050794 regulation of cellular process
1.26 4.38e-04 GO:0050789 regulation of biological process
1.24 1.11e-03 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
5.17 1.47e-02 GO:0044309 neuron spine
4.94 3.46e-03 GO:0030426 growth cone
4.79 4.69e-03 GO:0030427 site of polarized growth
1.15 4.88e-04 GO:0044424 intracellular part
1.15 2.32e-02 GO:0043226 organelle
1.15 2.71e-02 GO:0043229 intracellular organelle
1.14 7.63e-04 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
5.85 8.85e-04 GO:0004879 ligand-dependent nuclear receptor activity
5.63 3.70e-03 GO:0003707 steroid hormone receptor activity
2.31 2.54e-03 GO:0019904 protein domain specific binding
1.88 3.28e-02 GO:0043565 sequence-specific DNA binding
1.79 5.46e-03 GO:0001071 nucleic acid binding transcription factor activity
1.79 5.46e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.78 5.70e-03 GO:0030528 transcription regulator activity
1.24 1.03e-03 GO:0005515 protein binding
1.13 2.34e-03 GO:0005488 binding