Motif ID: UUGGUCC

Z-value: 0.546


Mature miRNA associated with seed UUGGUCC:

NamemiRBase Accession
hsa-miR-133a MIMAT0000427
hsa-miR-133b MIMAT0000770



Activity profile for motif UUGGUCC.

activity profile for motif UUGGUCC


Sorted Z-values histogram for motif UUGGUCC

Sorted Z-values for motif UUGGUCC



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGGUCC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_93029864 0.807 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_93111915 0.775 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_93107881 0.766 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr8_-_93107442 0.728 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr7_+_30960914 0.711 NM_001185060
NM_001185061
NM_001185062
AQP1


aquaporin 1 (Colton blood group)


chr8_-_93115453 0.693 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr8_-_93075190 0.679 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_+_133971862 0.629 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr7_+_30951414 0.623 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr3_+_43328001 0.594 NM_001100594
NM_017719
SNRK

SNF related kinase

chr1_+_33231227 0.577 NM_001198972
NM_001198973
KIAA1522

KIAA1522

chr1_+_61542928 0.576 NM_001145511
NFIA
nuclear factor I/A
chr1_+_61547625 0.573 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr1_+_25870043 0.569 NM_015627
LDLRAP1
low density lipoprotein receptor adaptor protein 1
chr1_+_61547388 0.567 NM_001145512
NFIA
nuclear factor I/A
chr8_-_28243941 0.562 NM_018660
ZNF395
zinc finger protein 395
chr1_+_33207343 0.542 NM_020888
KIAA1522
KIAA1522
chr9_-_8733893 0.519 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr9_-_10612722 0.517 NM_002839
PTPRD
protein tyrosine phosphatase, receptor type, D
chr10_+_112257624 0.483 NM_004419
DUSP5
dual specificity phosphatase 5
chr6_+_160182988 0.475 NM_005891
ACAT2
acetyl-CoA acetyltransferase 2
chr9_-_14398981 0.473 NM_001190738
NFIB
nuclear factor I/B
chr7_-_100425035 0.451 NM_004444
EPHB4
EPH receptor B4
chr20_-_47444404 0.447 NM_020820
PREX1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr2_+_177053306 0.434 NM_024501
HOXD1
homeobox D1
chr16_+_14164879 0.434 NM_014048
MKL2
MKL/myocardin-like 2
chr9_-_14314036 0.420 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr1_+_109102970 0.414 NM_001010883
FAM102B
family with sequence similarity 102, member B
chr6_+_1610680 0.402 NM_001453
FOXC1
forkhead box C1
chr2_+_203499819 0.397 NM_173511
FAM117B
family with sequence similarity 117, member B
chr2_-_209119751 0.389 NM_005896
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr3_-_168865521 0.388 NM_001164000
MECOM
MDS1 and EVI1 complex locus
chr2_+_66662516 0.387 NM_002398
MEIS1
Meis homeobox 1
chr3_-_15900928 0.384 NM_015199
ANKRD28
ankyrin repeat domain 28
chr3_-_168864325 0.377 NM_001105078
MECOM
MDS1 and EVI1 complex locus
chr3_-_168864066 0.375 NM_001105077
NM_001163999
NM_005241
MECOM


MDS1 and EVI1 complex locus


chr3_-_15839674 0.368 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr6_+_11538486 0.363 NM_001100829
TMEM170B
transmembrane protein 170B
chr6_+_24495166 0.361 NM_001080
NM_170740
ALDH5A1

aldehyde dehydrogenase 5 family, member A1

chrX_+_107069081 0.340 NM_012216
NM_052817
MID2

midline 2

chr8_-_80993009 0.335 NM_001025252
TPD52
tumor protein D52
chr8_-_38326351 0.329 NM_001174063
NM_001174064
NM_015850
NM_023105
NM_023106
NM_023110
FGFR1





fibroblast growth factor receptor 1





chr11_+_119019749 0.328 NM_022169
ABCG4
ATP-binding cassette, sub-family G (WHITE), member 4
chr3_-_39195101 0.322 NM_033027
CSRNP1
cysteine-serine-rich nuclear protein 1
chr16_+_29823408 0.322 NM_145239
PRRT2
proline-rich transmembrane protein 2
chr20_+_11898536 0.314 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr11_+_119020298 0.313 NM_001142505
ABCG4
ATP-binding cassette, sub-family G (WHITE), member 4
chr11_+_64058772 0.312 NM_033310
KCNK4
potassium channel, subfamily K, member 4
chr20_+_11871364 0.310 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr6_+_107811272 0.307 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr19_-_14629160 0.306 NM_006145
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr9_-_20622476 0.301 NM_004529
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr16_-_10674443 0.300 NM_001424
EMP2
epithelial membrane protein 2
chr12_+_10365415 0.297 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr10_-_126716452 0.295 NM_022802
CTBP2
C-terminal binding protein 2
chr8_-_81083660 0.283 NM_001025253
NM_005079
TPD52

tumor protein D52

chr11_+_44785975 0.283 NM_130783
TSPAN18
tetraspanin 18
chr17_+_61699786 0.280 NM_002401
NM_203351
MAP3K3

mitogen-activated protein kinase kinase kinase 3

chr2_+_33359607 0.279 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr2_+_33172368 0.279 NM_206943
LTBP1
latent transforming growth factor beta binding protein 1
chr8_-_38325241 0.278 NM_001174065
NM_001174066
NM_001174067
FGFR1


fibroblast growth factor receptor 1


chr10_+_102756829 0.271 NM_032429
LZTS2
leucine zipper, putative tumor suppressor 2
chr9_+_115513050 0.271 NM_001012994
SNX30
sorting nexin family member 30
chr19_-_10444186 0.270 NM_133452
RAVER1
ribonucleoprotein, PTB-binding 1
chr6_-_53409897 0.266 NM_001197115
NM_001498
GCLC

glutamate-cysteine ligase, catalytic subunit

chr14_-_78083109 0.265 NM_004863
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr10_-_126849066 0.263 NM_001329
CTBP2
C-terminal binding protein 2
chr2_-_27485774 0.262 NM_003459
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr2_+_191745546 0.251 NM_014905
GLS
glutaminase
chr10_-_126849556 0.249 NM_001083914
CTBP2
C-terminal binding protein 2
chr10_-_32217762 0.248 NM_018287
ARHGAP12
Rho GTPase activating protein 12
chr16_-_67184822 0.247 NM_033309
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr2_-_26205437 0.247 NM_002254
KIF3C
kinesin family member 3C
chr3_-_15798057 0.246 NM_001195099
ANKRD28
ankyrin repeat domain 28
chr7_+_101460881 0.244 NM_181552
CUX1
cut-like homeobox 1
chr17_+_7387688 0.244 NM_000937
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr1_+_97187174 0.242 NM_021190
PTBP2
polypyrimidine tract binding protein 2
chr20_-_35488275 0.240 NM_199181
KIAA0889
KIAA0889
chr17_+_73043154 0.238 NM_015353
KCTD2
potassium channel tetramerisation domain containing 2
chr1_-_36184727 0.238 NM_152374
C1orf216
chromosome 1 open reading frame 216
chr6_+_72922513 0.235 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr4_-_89744154 0.223 NM_001015045
FAM13A
family with sequence similarity 13, member A
chr19_+_34287662 0.221 NM_001129994
NM_001129995
NM_024076
KCTD15


potassium channel tetramerisation domain containing 15


chr14_-_90085325 0.215 NM_001085471
FOXN3
forkhead box N3
chr19_+_1026271 0.214 NM_004368
NM_201277
CNN2

calponin 2

chr9_+_2015218 0.213 NM_003070
NM_139045
SMARCA2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr6_-_7910278 0.213 NM_001145549
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr8_+_22423170 0.212 NM_001018003
SORBS3
sorbin and SH3 domain containing 3
chr6_+_73076431 0.210 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr6_+_72926144 0.209 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chrX_-_119709618 0.207 NM_003588
CUL4B
cullin 4B
chr5_+_149380168 0.206 NM_014983
HMGXB3
HMG box domain containing 3
chr16_+_30406432 0.204 NM_001214909
ZNF48
zinc finger protein 48
chr3_-_169381417 0.203 NM_001205194
NM_004991
MECOM

MDS1 and EVI1 complex locus

chr19_+_797390 0.203 NM_002819
NM_031990
NM_031991
NM_175847
PTBP1



polypyrimidine tract binding protein 1



chr3_-_148804122 0.202 NM_003071
NM_139048
HLTF

helicase-like transcription factor

chr22_+_40573879 0.198 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr16_+_30389632 0.198 NM_001214906
NM_001214907
ZNF48

zinc finger protein 48

chr12_+_79257772 0.196 NM_001135805
SYT1
synaptotagmin I
chr9_-_101470836 0.195 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr19_+_2164119 0.194 NM_032482
DOT1L
DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chr3_-_123135188 0.192 NM_001199642
ADCY5
adenylate cyclase 5
chr9_+_131102786 0.189 NM_005094
SLC27A4
solute carrier family 27 (fatty acid transporter), member 4
chr9_+_131873592 0.189 NM_178000
NM_178001
NM_178003
PPP2R4


protein phosphatase 2A activator, regulatory subunit 4


chr16_-_30457197 0.188 NM_012248
SEPHS2
selenophosphate synthetase 2
chr17_+_7788094 0.188 NM_001005271
CHD3
chromodomain helicase DNA binding protein 3
chr12_+_79439432 0.188 NM_001135806
SYT1
synaptotagmin I
chr12_+_56521953 0.187 NM_001184796
NM_015292
ESYT1

extended synaptotagmin-like protein 1

chr14_-_89883306 0.186 NM_005197
FOXN3
forkhead box N3
chr11_-_61584451 0.184 NM_013402
FADS1
fatty acid desaturase 1
chr16_+_30406711 0.184 NM_152652
ZNF48
zinc finger protein 48
chr3_+_25469833 0.182 NM_000965
RARB
retinoic acid receptor, beta
chr16_-_4588379 0.181 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr6_+_72926462 0.181 NM_001168410
RIMS1
regulating synaptic membrane exocytosis 1
chr1_-_29450406 0.181 NM_001003682
TMEM200B
transmembrane protein 200B
chr7_-_27205148 0.178 NM_152739
HOXA9
homeobox A9
chr9_+_131873752 0.178 NM_001193397
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr13_-_110438896 0.174 NM_003749
IRS2
insulin receptor substrate 2
chr15_-_37393364 0.174 NM_001220482
NM_002399
MEIS2

Meis homeobox 2

chr8_-_127570710 0.174 NM_174911
FAM84B
family with sequence similarity 84, member B
chr6_-_80656870 0.173 NM_022726
ELOVL4
ELOVL fatty acid elongase 4
chr20_-_3388219 0.171 NM_001009984
C20orf194
chromosome 20 open reading frame 194
chr5_-_172198160 0.170 NM_004417
DUSP1
dual specificity phosphatase 1
chr17_-_47841517 0.169 NM_030802
FAM117A
family with sequence similarity 117, member A
chr7_-_138665853 0.168 NM_001164665
NM_020910
KIAA1549

KIAA1549

chr1_-_29449012 0.168 NM_001171868
TMEM200B
transmembrane protein 200B
chrX_-_119694719 0.167 NM_001079872
CUL4B
cullin 4B
chr2_-_69870976 0.165 NM_014911
AAK1
AP2 associated kinase 1
chrX_-_25034064 0.162 NM_139058
ARX
aristaless related homeobox
chr6_-_119031230 0.162 NM_001178035
CEP85L
centrosomal protein 85kDa-like
chr8_-_66753968 0.162 NM_001242318
PDE7A
phosphodiesterase 7A
chr15_-_37390372 0.161 NM_172315
MEIS2
Meis homeobox 2
chr16_-_4588738 0.159 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr8_-_145838887 0.158 NM_025251
ARHGAP39
Rho GTPase activating protein 39
chr15_+_91411884 0.156 NM_002569
FURIN
furin (paired basic amino acid cleaving enzyme)
chr8_+_22409226 0.156 NM_005775
SORBS3
sorbin and SH3 domain containing 3
chr14_+_24899139 0.153 NM_015299
KHNYN
KH and NYN domain containing
chr17_-_39942937 0.150 NM_002230
NM_021991
JUP

junction plakoglobin

chr17_+_60704747 0.150 NM_006039
MRC2
mannose receptor, C type 2
chr3_-_196159304 0.148 NM_015562
UBXN7
UBX domain protein 7
chr17_-_27045172 0.147 NM_001142624
NM_001142625
NM_001144943
RAB34


RAB34, member RAS oncogene family


chr3_-_186524226 0.146 NM_002916
RFC4
replication factor C (activator 1) 4, 37kDa
chr3_-_186524483 0.146 NM_181573
RFC4
replication factor C (activator 1) 4, 37kDa
chr6_-_7910716 0.145 NM_030810
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr6_+_21593963 0.145 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr5_+_43121641 0.143 NM_003432
ZNF131
zinc finger protein 131
chr12_+_79258448 0.143 NM_005639
SYT1
synaptotagmin I
chr8_+_38034066 0.142 NM_001204878
NM_004874
BAG4

BCL2-associated athanogene 4

chr22_+_40440664 0.142 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr13_+_58205788 0.141 NM_001040429
PCDH17
protocadherin 17
chr19_-_7293876 0.141 NM_000208
NM_001079817
INSR

insulin receptor

chr8_-_23021447 0.141 NM_003840
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr17_-_79881304 0.140 NM_032711
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr9_+_131873227 0.138 NM_021131
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr3_-_123167391 0.138 NM_183357
ADCY5
adenylate cyclase 5
chr11_-_88781039 0.133 NM_001143831
GRM5
glutamate receptor, metabotropic 5
chrX_-_140271293 0.132 NM_012317
LDOC1
leucine zipper, down-regulated in cancer 1
chr11_-_118927872 0.132 NM_006389
NM_001130991
HYOU1

hypoxia up-regulated 1

chr17_-_48227873 0.132 NM_032595
PPP1R9B
protein phosphatase 1, regulatory subunit 9B
chr19_-_14316980 0.132 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr2_-_130939146 0.130 NM_001171083
NM_017751
NM_017951
SMPD4


sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)


chr15_-_37391596 0.130 NM_172316
MEIS2
Meis homeobox 2
chr12_-_50222144 0.129 NM_001037806
NCKAP5L
NCK-associated protein 5-like
chr12_+_56137063 0.129 NM_005811
GDF11
growth differentiation factor 11
chr12_+_15699277 0.128 NM_030668
NM_030669
NM_030670
NM_030671
PTPRO



protein tyrosine phosphatase, receptor type, O



chr3_+_5229357 0.126 NM_014674
EDEM1
ER degradation enhancer, mannosidase alpha-like 1
chr8_+_29952921 0.126 NM_001128208
NM_015344
LEPROTL1

leptin receptor overlapping transcript-like 1

chr4_-_141075232 0.126 NM_018717
MAML3
mastermind-like 3 (Drosophila)
chr12_-_82153092 0.126 NM_003625
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr3_-_13114547 0.125 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr7_+_102073953 0.122 NM_001126340
NM_032831
ORAI2

ORAI calcium release-activated calcium modulator 2

chr13_+_98795410 0.122 NM_001001715
NM_005766
FARP1

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

chr16_-_66584045 0.122 NM_001172643
NM_001172644
NM_001172645
NM_004614
TK2



thymidine kinase 2, mitochondrial



chr18_-_812268 0.122 NM_005433
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr6_-_166075520 0.120 NM_006661
NM_001130690
PDE10A

phosphodiesterase 10A

chr17_+_7792034 0.120 NM_001005273
NM_005852
CHD3

chromodomain helicase DNA binding protein 3

chr17_+_635656 0.120 NM_024792
FAM57A
family with sequence similarity 57, member A
chr17_-_7387513 0.119 NM_020899
ZBTB4
zinc finger and BTB domain containing 4
chr1_+_11866206 0.117 NM_001286
NM_021735
NM_021736
NM_021737
CLCN6



chloride channel 6



chr17_-_66287256 0.117 NM_001174166
NM_004694
SLC16A6

solute carrier family 16, member 6 (monocarboxylic acid transporter 7)

chr1_-_179112178 0.116 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr12_+_50478942 0.114 NM_003076
NM_139071
SMARCD1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1

chr16_-_1429612 0.114 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr19_-_46272496 0.113 NM_175875
SIX5
SIX homeobox 5
chr16_+_58549382 0.112 NM_001160305
NM_024860
SETD6

SET domain containing 6

chr17_-_7382943 0.110 NM_001128833
ZBTB4
zinc finger and BTB domain containing 4
chr17_-_79885544 0.109 NM_002359
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr8_+_67039130 0.106 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr17_-_53800074 0.106 NM_018286
TMEM100
transmembrane protein 100
chr12_-_54778456 0.104 NM_015481
ZNF385A
zinc finger protein 385A
chr15_+_85359910 0.103 NM_020778
ALPK3
alpha-kinase 3
chr1_+_32573619 0.103 NM_012316
KPNA6
karyopherin alpha 6 (importin alpha 7)
chr4_+_111397181 0.102 NM_001977
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr17_-_53809444 0.102 NM_001099640
TMEM100
transmembrane protein 100
chr17_+_80477564 0.101 NM_004514
FOXK2
forkhead box K2
chr17_-_27044728 0.101 NM_001144942
NM_031934
RAB34

RAB34, member RAS oncogene family

chr15_-_37392358 0.101 NM_170674
NM_170675
NM_170676
NM_170677
MEIS2



Meis homeobox 2



chr2_-_197791339 0.101 NM_024989
PGAP1
post-GPI attachment to proteins 1
chr16_-_15736964 0.101 NM_001184998
NM_001184999
NM_014647
KIAA0430


KIAA0430


chr9_-_37034358 0.100 NM_016734
PAX5
paired box 5

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.32 3.47e-04 GO:0050794 regulation of cellular process
1.29 6.61e-04 GO:0050789 regulation of biological process
1.28 6.92e-04 GO:0065007 biological regulation
2.14 2.82e-03 GO:0006351 transcription, DNA-dependent
1.93 3.78e-02 GO:0032774 RNA biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 5.27e-03 GO:0044464 cell part
1.08 5.35e-03 GO:0005623 cell
9.99 5.61e-03 GO:0030140 trans-Golgi network transport vesicle
3.57 5.76e-03 GO:0030136 clathrin-coated vesicle
1.18 6.85e-03 GO:0043229 intracellular organelle
1.30 7.86e-03 GO:0005634 nucleus
1.18 8.13e-03 GO:0043226 organelle
4.51 1.93e-02 GO:0030665 clathrin coated vesicle membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.98 1.77e-03 GO:0001071 nucleic acid binding transcription factor activity
1.98 1.77e-03 GO:0003700 sequence-specific DNA binding transcription factor activity