Motif ID: UUGUUCG

Z-value: 0.579


Mature miRNA associated with seed UUGUUCG:

NamemiRBase Accession
hsa-miR-375 MIMAT0000728



Activity profile for motif UUGUUCG.

activity profile for motif UUGUUCG


Sorted Z-values histogram for motif UUGUUCG

Sorted Z-values for motif UUGUUCG



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGUUCG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_79086087 0.728 NM_006820
 IFI44L
interferon-induced protein 44-like
chr4_-_79860369 0.439 NM_001040202
 PAQR3
progestin and adipoQ receptor family member III
chr7_-_102715014 0.359 NM_145032
 FBXL13
F-box and leucine-rich repeat protein 13
chr7_-_102715171 0.353 NM_001111038
 FBXL13
F-box and leucine-rich repeat protein 13
chr11_-_86666211 0.347 NM_012193
 FZD4
frizzled family receptor 4
chr5_-_59189620 0.341 NM_001104631
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58295758 0.325 NM_001197223
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58334936 0.318 NM_001197221
NM_001197222
 PDE4D

phosphodiesterase 4D, cAMP-specific

chr1_+_162466963 0.303 NM_001184763
 UHMK1
U2AF homology motif (UHM) kinase 1
chr1_+_162467594 0.295 NM_144624
NM_175866
 UHMK1

U2AF homology motif (UHM) kinase 1

chr5_-_59783885 0.291 NM_001165899
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_-_27183225 0.277 NM_019102
 HOXA5
homeobox A5
chr5_-_58571916 0.268 NM_001197220
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr17_+_5031686 0.257 NM_004505
 USP6
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr5_-_58652671 0.250 NM_001197219
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_-_27159213 0.245 NM_030661
 HOXA3
homeobox A3
chr8_-_94753211 0.241 NM_203390
 RBM12B
RNA binding motif protein 12B
chr12_-_89919182 0.239 NM_001199777
 POC1B
POC1 centriolar protein homolog B (Chlamydomonas)
chr7_-_27166638 0.239 NM_153631
 HOXA3
homeobox A3
chr5_-_59064437 0.237 NM_001197218
 PDE4D
phosphodiesterase 4D, cAMP-specific

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
32.92 4.75e-02 GO:0021563 glossopharyngeal nerve development
32.92 4.75e-02 GO:0021615 glossopharyngeal nerve morphogenesis
3.34 4.60e-02 GO:0006417 regulation of translation
2.65 1.84e-02 GO:0070647 protein modification by small protein conjugation or removal
2.49 3.64e-02 GO:0009792 embryo development ending in birth or egg hatching
2.06 3.34e-02 GO:0009790 embryo development
1.83 4.47e-02 GO:0032268 regulation of cellular protein metabolic process
1.78 1.00e-04 GO:0006464 protein modification process
1.77 2.59e-03 GO:0009653 anatomical structure morphogenesis
1.75 1.42e-04 GO:0043412 macromolecule modification
1.72 1.35e-02 GO:0007399 nervous system development
1.62 8.11e-05 GO:0031326 regulation of cellular biosynthetic process
1.62 8.14e-05 GO:0009889 regulation of biosynthetic process
1.60 1.29e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.57 2.51e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.56 3.65e-03 GO:0044267 cellular protein metabolic process
1.49 2.80e-02 GO:0010468 regulation of gene expression
1.48 6.88e-04 GO:0031323 regulation of cellular metabolic process
1.48 8.74e-04 GO:0080090 regulation of primary metabolic process
1.48 1.72e-03 GO:0060255 regulation of macromolecule metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
1.54 2.43e-02 GO:0031981 nuclear lumen
1.53 5.44e-03 GO:0044428 nuclear part
1.49 1.44e-02 GO:0070013 intracellular organelle lumen
1.47 2.11e-02 GO:0031974 membrane-enclosed lumen
1.46 3.03e-02 GO:0043233 organelle lumen
1.34 1.33e-04 GO:0005634 nucleus
1.27 1.54e-02 GO:0044446 intracellular organelle part
1.26 2.35e-06 GO:0043231 intracellular membrane-bounded organelle
1.26 2.72e-06 GO:0043227 membrane-bounded organelle
1.26 2.65e-02 GO:0044422 organelle part
1.21 6.92e-05 GO:0043229 intracellular organelle
1.20 8.68e-05 GO:0043226 organelle
1.16 1.85e-04 GO:0044424 intracellular part
1.14 1.16e-03 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.91 2.43e-02 GO:0019899 enzyme binding
1.77 2.41e-02 GO:0030528 transcription regulator activity
1.48 1.82e-02 GO:0000166 nucleotide binding
1.23 7.24e-03 GO:0005515 protein binding
1.16 2.92e-05 GO:0005488 binding