Motif ID: XBP1.p3

Z-value: 3.173


Transcription factors associated with XBP1.p3:

Gene SymbolEntrez IDGene Name
XBP1 7494 X-box binding protein 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
XBP1chr22_-_291964520.404.8e-02Click!


Activity profile for motif XBP1.p3.

activity profile for motif XBP1.p3


Sorted Z-values histogram for motif XBP1.p3

Sorted Z-values for motif XBP1.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of XBP1.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_121413906 12.691 LOX
lysyl oxidase
chr5_-_121414011 11.191 NM_002317
 LOX
lysyl oxidase
chr9_+_35732498 11.145 CREB3
cAMP responsive element binding protein 3
chr9_+_35732207 10.542 NM_006368
 CREB3
cAMP responsive element binding protein 3
chr9_+_35732629 10.424 CREB3
cAMP responsive element binding protein 3
chr19_+_50031232 9.054 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr22_-_31503484 6.700 NM_080430
 SELM
selenoprotein M
chr2_-_69614321 6.610 NM_001244710
NM_002056
 GFPT1

glutamine--fructose-6-phosphate transaminase 1

chr6_-_33168448 6.567 RXRB
retinoid X receptor, beta
chr1_+_26758772 6.309 NM_001243564
NM_001243565
NM_024887
NM_205861
 DHDDS



dehydrodolichyl diphosphate synthase



chr5_-_121413967 5.686 LOX
lysyl oxidase
chr6_+_116692098 5.479 NM_013352
 DSE
dermatan sulfate epimerase
chr11_+_69455938 5.415 CCND1
cyclin D1
chr6_-_90062450 5.176 UBE2J1
ubiquitin-conjugating enzyme E2, J1, U
chr6_-_90062610 5.128 NM_016021
 UBE2J1
ubiquitin-conjugating enzyme E2, J1, U
chr11_-_207379 5.077 BET1L
blocked early in transport 1 homolog (S. cerevisiae)-like
chr6_+_83903031 5.075 NM_033411
 RWDD2A
RWD domain containing 2A
chr4_+_38869346 4.962 NM_138389
 FAM114A1
family with sequence similarity 114, member A1
chr6_-_83902921 4.948 NM_001199918
NM_001199919
NM_015599
 PGM3


phosphoglucomutase 3


chr7_-_30066124 4.822 NM_017946
 FKBP14
FK506 binding protein 14, 22 kDa

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 46 entries
enrichment   p-value GO term description
21.67 1.66e-03 GO:0048207 vesicle targeting, rough ER to cis-Golgi
21.67 1.66e-03 GO:0048208 COPII vesicle coating
21.67 1.66e-03 GO:0090114 COPII-coated vesicle budding
19.50 3.65e-02 GO:0045047 protein targeting to ER
19.50 3.65e-02 GO:0072599 establishment of protein localization in endoplasmic reticulum
17.55 7.57e-07 GO:0048199 vesicle targeting, to, from or within Golgi
16.06 1.43e-04 GO:0070972 protein localization in endoplasmic reticulum
14.63 5.38e-06 GO:0006901 vesicle coating
14.04 8.22e-06 GO:0006900 membrane budding
13.93 2.37e-02 GO:0007029 endoplasmic reticulum organization
13.00 2.76e-06 GO:0006903 vesicle targeting
11.15 1.42e-02 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
9.29 1.03e-04 GO:0051650 establishment of vesicle localization
9.00 6.21e-04 GO:0006888 ER to Golgi vesicle-mediated transport
7.71 6.64e-08 GO:0018196 peptidyl-asparagine modification
7.71 6.64e-08 GO:0018279 protein N-linked glycosylation via asparagine
7.63 2.14e-08 GO:0006487 protein N-linked glycosylation
7.36 1.06e-03 GO:0051648 vesicle localization
7.20 1.07e-04 GO:0016050 vesicle organization
6.80 4.15e-10 GO:0048193 Golgi vesicle transport

Gene overrepresentation in compartment category:

Showing 1 to 20 of 44 entries
enrichment   p-value GO term description
19.50 7.17e-03 GO:0030127 COPII vesicle coat
16.72 1.80e-04 GO:0030663 COPI coated vesicle membrane
15.60 2.06e-02 GO:0008250 oligosaccharyltransferase complex
14.63 4.59e-04 GO:0012507 ER to Golgi transport vesicle membrane
13.77 6.93e-04 GO:0030137 COPI-coated vesicle
13.00 4.67e-02 GO:0030126 COPI vesicle coat
12.32 1.46e-03 GO:0030134 ER to Golgi transport vesicle
9.57 1.46e-07 GO:0005793 ER-Golgi intermediate compartment
8.00 1.39e-03 GO:0030120 vesicle coat
7.31 3.67e-02 GO:0030660 Golgi-associated vesicle membrane
7.09 2.50e-05 GO:0030117 membrane coat
7.09 2.50e-05 GO:0048475 coated membrane
5.09 6.28e-05 GO:0030662 coated vesicle membrane
4.73 2.19e-03 GO:0005788 endoplasmic reticulum lumen
3.63 1.41e-05 GO:0030659 cytoplasmic vesicle membrane
3.57 8.53e-04 GO:0030135 coated vesicle
3.51 2.70e-05 GO:0012506 vesicle membrane
3.35 9.58e-09 GO:0000139 Golgi membrane
3.17 1.14e-12 GO:0044432 endoplasmic reticulum part
3.01 4.35e-04 GO:0044433 cytoplasmic vesicle part

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
17.34 1.55e-02 GO:0003756 protein disulfide isomerase activity
17.34 1.55e-02 GO:0016862 intramolecular oxidoreductase activity, interconverting keto- and enol-groups
17.34 1.55e-02 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds
8.36 2.04e-02 GO:0015035 protein disulfide oxidoreductase activity
7.55 3.74e-02 GO:0015036 disulfide oxidoreductase activity
4.59 1.97e-02 GO:0008565 protein transporter activity
3.66 3.55e-02 GO:0016853 isomerase activity