Motif ID: YY1.p2

Z-value: 1.837


Transcription factors associated with YY1.p2:

Gene SymbolEntrez IDGene Name
YY1 7528 YY1 transcription factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
YY1chr14_+_100705279,
chr14_+_100705101
-0.222.8e-01Click!


Activity profile for motif YY1.p2.

activity profile for motif YY1.p2


Sorted Z-values histogram for motif YY1.p2

Sorted Z-values for motif YY1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of YY1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_15848422 3.541 ADORA2B
adenosine A2b receptor
chr16_+_57406398 3.347 NM_002996
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr21_+_43639202 2.746 NM_004915
NM_016818
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr17_-_31204071 2.245 MYO1D
myosin ID
chr8_-_48650683 2.216 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr11_+_122526339 2.129 NM_032873
UBASH3B
ubiquitin associated and SH3 domain containing B
chr2_+_102979096 2.023 NM_003855
IL18R1
interleukin 18 receptor 1
chr15_+_67358194 2.016 NM_005902
SMAD3
SMAD family member 3
chr1_+_101361649 1.997 SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr1_-_161102457 1.908 NM_001039711
NM_032998
DEDD

death effector domain containing

chr14_-_55369163 1.848 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr14_+_65007418 1.805 HSPA2
heat shock 70kDa protein 2
chr15_+_89182038 1.792 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr10_+_73571639 1.779 NM_001171935
NM_001171936
CDH23

cadherin-related 23

chr6_-_47254143 1.645 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr6_+_135502521 1.621 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr13_-_26625164 1.607 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr12_-_108954942 1.602 SART3
squamous cell carcinoma antigen recognized by T cells 3
chr17_-_17399494 1.584 NM_001199989
NM_016084
RASD1

RAS, dexamethasone-induced 1

chr12_-_108954952 1.581 SART3
squamous cell carcinoma antigen recognized by T cells 3
chr13_-_107187312 1.564 NM_004093
EFNB2
ephrin-B2
chr1_-_161102367 1.564 DEDD
death effector domain containing
chr8_+_90770201 1.534 RIPK2
receptor-interacting serine-threonine kinase 2
chr14_-_53417272 1.513 FERMT2
fermitin family member 2
chr9_-_38069082 1.500 SHB
Src homology 2 domain containing adaptor protein B
chr11_+_111473099 1.493 NM_015191
SIK2
salt-inducible kinase 2
chr8_-_48650703 1.454 NM_005195
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr15_+_67358161 1.438 SMAD3
SMAD family member 3
chr5_-_158635080 1.422 NM_001199381
RNF145
ring finger protein 145
chr14_-_21852085 1.377 SUPT16H
suppressor of Ty 16 homolog (S. cerevisiae)
chr5_+_139060295 1.340 CXXC5
CXXC finger protein 5
chr8_+_90769974 1.338 NM_003821
RIPK2
receptor-interacting serine-threonine kinase 2
chr11_+_93862060 1.322 NM_015368
PANX1
pannexin 1
chr11_+_93862143 1.319 PANX1
pannexin 1
chr5_-_158634833 1.318 NM_144726
RNF145
ring finger protein 145
chr14_-_21852161 1.306 SUPT16H
suppressor of Ty 16 homolog (S. cerevisiae)
chr14_+_55168831 1.287 SAMD4A
sterile alpha motif domain containing 4A
chr8_+_23386386 1.271 SLC25A37
solute carrier family 25, member 37
chr17_+_26369617 1.265 NM_016231
NLK
nemo-like kinase
chr6_-_37225360 1.250 NM_145316
TMEM217
transmembrane protein 217
chr20_-_17641122 1.247 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chr5_-_158634641 1.247 NM_001199382
RNF145
ring finger protein 145
chr19_-_50413063 1.246 NUP62
nucleoporin 62kDa
chr6_-_47253962 1.225 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr11_+_109964086 1.222 NM_033390
ZC3H12C
zinc finger CCCH-type containing 12C
chr20_-_43977023 1.218 NM_002999
SDC4
syndecan 4
chr8_+_86089641 1.216


chr17_+_26369935 1.209 NLK
nemo-like kinase
chr17_-_3301703 1.161 NM_003553
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr15_+_93443559 1.152 CHD2
chromodomain helicase DNA binding protein 2
chr19_-_49658645 1.148 NM_002152
HRC
histidine rich calcium binding protein
chr17_+_4402128 1.118 NM_001124758
SPNS2
spinster homolog 2 (Drosophila)
chr6_+_33168602 1.110 NM_001077516
NM_006979
SLC39A7

solute carrier family 39 (zinc transporter), member 7

chr5_-_158636489 1.103 NM_001199383
RNF145
ring finger protein 145
chr7_+_150065968 1.091 REPIN1
replication initiator 1
chr14_-_53417636 1.082 FERMT2
fermitin family member 2
chr13_+_97928196 1.074 MBNL2
muscleblind-like 2 (Drosophila)
chr1_+_101361688 1.066 SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr13_+_97928414 1.047 MBNL2
muscleblind-like 2 (Drosophila)
chr17_-_63052707 1.022 GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr5_+_113698304 1.018 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr20_-_34243118 1.010 RBM12
RNA binding motif protein 12
chr5_+_113698015 0.972 NM_021614
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr1_+_212788359 0.967 NM_001206486
ATF3
activating transcription factor 3
chr3_+_42190825 0.965 TRAK1
trafficking protein, kinesin binding 1
chr8_+_23386468 0.945 SLC25A37
solute carrier family 25, member 37
chr1_-_161102210 0.940 NM_001039712
DEDD
death effector domain containing
chr17_-_41856180 0.913 NM_004090
DUSP3
dual specificity phosphatase 3
chr1_-_235491448 0.890 ARID4B
AT rich interactive domain 4B (RBP1-like)
chr4_-_159092509 0.885 FAM198B
family with sequence similarity 198, member B
chr13_-_20357125 0.880 NM_001042414
PSPC1
paraspeckle component 1
chr1_+_114522029 0.876 NM_020190
OLFML3
olfactomedin-like 3
chr21_+_34775729 0.836 IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr19_+_54376975 0.829 MYADM
myeloid-associated differentiation marker
chr13_-_20356788 0.821 PSPC1
paraspeckle component 1
chr1_+_100818052 0.809 CDC14A
CDC14 cell division cycle 14 homolog A (S. cerevisiae)
chr15_+_44719765 0.808 CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr5_-_139943829 0.806 APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr5_+_131409484 0.802 NM_000758
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr6_+_12012723 0.786 NM_002114
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr6_+_135502477 0.782 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr21_+_47545896 0.774 COL6A2
collagen, type VI, alpha 2
chr6_+_135502445 0.774 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr16_+_75681634 0.770 NM_018975
TERF2IP
telomeric repeat binding factor 2, interacting protein
chr9_-_123476578 0.770 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr1_-_55681024 0.767 NM_015306
USP24
ubiquitin specific peptidase 24
chr8_+_23386362 0.761 NM_016612
SLC25A37
solute carrier family 25, member 37
chr17_+_20108298 0.759 SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr16_-_23160509 0.759 NM_020718
USP31
ubiquitin specific peptidase 31
chr15_+_90931509 0.757 IQGAP1
IQ motif containing GTPase activating protein 1
chr6_+_108882104 0.757 FOXO3
forkhead box O3
chr1_-_154193044 0.756 C1orf43
chromosome 1 open reading frame 43
chr17_-_3337134 0.754 NM_003554
OR1E2
olfactory receptor, family 1, subfamily E, member 2
chr19_+_39390567 0.750 NM_002503
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr17_-_76719671 0.750 CYTH1
cytohesin 1
chr16_+_84733606 0.748 USP10
ubiquitin specific peptidase 10
chr18_-_48723689 0.747 MEX3C
mex-3 homolog C (C. elegans)
chr19_-_1020995 0.745 C19orf6
chromosome 19 open reading frame 6
chr9_-_123688352 0.743 TRAF1
TNF receptor-associated factor 1
chr11_-_8892909 0.724 ST5
suppression of tumorigenicity 5
chr12_+_56862300 0.720 NM_207344
SPRYD4
SPRY domain containing 4
chr8_-_119123804 0.719 NM_000127
EXT1
exostosin 1
chr3_+_133292714 0.719 CDV3
CDV3 homolog (mouse)
chr22_+_39916563 0.719 NM_001675
NM_182810
ATF4

activating transcription factor 4 (tax-responsive enhancer element B67)

chr19_-_1021122 0.711 NM_001033026
NM_033420
C19orf6

chromosome 19 open reading frame 6

chr10_+_28966419 0.710 NM_012342
BAMBI
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
chr1_-_150602047 0.708 ENSA
endosulfine alpha
chr16_+_86544104 0.706 NM_001451
FOXF1
forkhead box F1
chr19_+_46850245 0.705 NM_001204284
NM_006247
PPP5C

protein phosphatase 5, catalytic subunit

chr2_+_61108702 0.705 REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chrX_-_136113832 0.695 NM_054021
GPR101
G protein-coupled receptor 101
chr1_-_200377488 0.694 ZNF281
zinc finger protein 281
chr21_+_34775740 0.692 IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr21_+_34922923 0.691 SON
SON DNA binding protein
chr10_+_28822508 0.690 WAC
WW domain containing adaptor with coiled-coil
chr11_+_75526236 0.687 UVRAG
UV radiation resistance associated gene
chr2_+_61108724 0.686 NM_002908
REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr12_-_108954929 0.682 SART3
squamous cell carcinoma antigen recognized by T cells 3
chr8_-_8750739 0.681 NM_004225
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chr1_+_222886058 0.679 BROX
BRO1 domain and CAAX motif containing
chr2_+_61108775 0.677 REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr20_+_6748744 0.677 NM_001200
BMP2
bone morphogenetic protein 2
chr4_+_4861371 0.675 NM_002448
MSX1
msh homeobox 1
chr12_-_120554558 0.671 RAB35
RAB35, member RAS oncogene family
chr13_-_20357043 0.671 PSPC1
paraspeckle component 1
chr1_-_150601911 0.664 ENSA
endosulfine alpha
chr10_+_35484054 0.660 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr5_-_139944045 0.657 NM_006051
NM_133172
NM_133173
NM_133174
APBB3



amyloid beta (A4) precursor protein-binding, family B, member 3



chr17_-_56084611 0.657 SRSF1
serine/arginine-rich splicing factor 1
chr6_+_127439803 0.655 RSPO3
R-spondin 3
chr14_+_104605059 0.645 NM_015656
KIF26A
kinesin family member 26A
chr22_+_31644368 0.641 LIMK2
LIM domain kinase 2
chr19_-_50432678 0.638 NUP62
nucleoporin 62kDa
chr15_-_71146427 0.636 NM_018357
NM_197958
LARP6

La ribonucleoprotein domain family, member 6

chr19_+_45504686 0.634 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr21_-_35986744 0.632 NM_203417
RCAN1
regulator of calcineurin 1
chr1_-_86043932 0.628 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr15_-_55563091 0.624 NM_183236
RAB27A
RAB27A, member RAS oncogene family
chr20_-_34330093 0.623 RBM39
RNA binding motif protein 39
chr1_-_149814264 0.622 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr19_-_2151332 0.620 AP3D1
adaptor-related protein complex 3, delta 1 subunit
chr14_-_57735527 0.618 EXOC5
exocyst complex component 5
chr1_-_150601554 0.616 NM_207045
NM_207046
NM_207047
ENSA


endosulfine alpha


chr17_+_7384720 0.614 NM_001102614
SLC35G6
solute carrier family 35, member G6
chr1_-_150552077 0.612 MCL1
myeloid cell leukemia sequence 1 (BCL2-related)
chr19_+_11546085 0.611 NM_001001329
NM_002743
PRKCSH

protein kinase C substrate 80K-H

chr10_+_105005643 0.609 NM_001143909
LOC729020
rcRPE
chr10_-_32636084 0.609 NM_025209
EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr1_+_100818007 0.602 NM_003672
NM_033312
NM_033313
CDC14A


CDC14 cell division cycle 14 homolog A (S. cerevisiae)


chr8_+_145515437 0.602 HSF1
heat shock transcription factor 1
chr15_-_50411405 0.601 NM_024837
ATP8B4
ATPase, class I, type 8B, member 4
chr2_-_145275086 0.601 ZEB2
zinc finger E-box binding homeobox 2
chr12_-_123920967 0.600 RILPL2
Rab interacting lysosomal protein-like 2
chr3_+_133292557 0.597 CDV3
CDV3 homolog (mouse)
chr19_+_39390258 0.597 NM_001243116
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr17_+_40985412 0.597 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr16_+_84733596 0.589 USP10
ubiquitin specific peptidase 10
chr7_+_150065859 0.588 NM_001099695
NM_001099696
NM_013400
REPIN1


replication initiator 1


chr9_+_114659439 0.588 UGCG
UDP-glucose ceramide glucosyltransferase
chr15_+_63413998 0.587 NM_032857
NM_171846
LACTB

lactamase, beta

chr19_+_11546485 0.582 PRKCSH
protein kinase C substrate 80K-H
chr3_+_133292404 0.582 NM_001134422
NM_017548
CDV3

CDV3 homolog (mouse)

chr2_+_68384986 0.580 NM_020143
PNO1
partner of NOB1 homolog (S. cerevisiae)
chr10_+_86131546 0.579 FAM190B
family with sequence similarity 190, member B
chr17_+_80332152 0.574 NM_018949
UTS2R
urotensin 2 receptor
chr11_-_10830034 0.574 EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr2_-_200820458 0.569 NM_001039693
TYW5
tRNA-yW synthesizing protein 5
chr15_-_69113213 0.566 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr15_+_44719831 0.562 CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr18_+_59992519 0.560 NM_003839
TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr8_+_25042379 0.559 DOCK5
dedicator of cytokinesis 5
chr10_-_61666184 0.557 CCDC6
coiled-coil domain containing 6
chr3_+_73045939 0.556 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr5_-_95297424 0.555 ELL2
elongation factor, RNA polymerase II, 2
chr6_+_27775898 0.555 NM_003509
HIST1H2AI
HIST1H2AM
HIST1H3F
histone cluster 1, H2ai
histone cluster 1, H2am
histone cluster 1, H3f
chr15_-_69113089 0.554 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr7_+_142919129 0.553 NM_176882
TAS2R40
taste receptor, type 2, member 40
chr8_+_9953061 0.553 NM_001135671
NM_001199729
MSRA

methionine sulfoxide reductase A

chr15_-_66084438 0.552 DENND4A
DENN/MADD domain containing 4A
chr5_-_137089434 0.552 HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr17_-_73389708 0.551 GRB2
growth factor receptor-bound protein 2
chr20_-_61557818 0.550 DIDO1
death inducer-obliterator 1
chr5_+_31799030 0.546 NM_178140
PDZD2
PDZ domain containing 2
chr2_+_219433517 0.546 NM_005444
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr9_+_114659023 0.545 NM_003358
UGCG
UDP-glucose ceramide glucosyltransferase
chr1_+_149822627 0.544 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr21_-_40685545 0.540 BRWD1
bromodomain and WD repeat domain containing 1
chr7_-_139477437 0.537 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr16_+_84733554 0.536 NM_005153
USP10
ubiquitin specific peptidase 10
chr17_-_79849362 0.536 THOC4
THO complex 4
chr6_+_4776826 0.535 CDYL
chromodomain protein, Y-like
chr15_-_66084544 0.531 NM_001144823
NM_005848
DENND4A

DENN/MADD domain containing 4A

chrX_+_70752911 0.528 NM_181672
NM_181673
OGT

O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)

chr12_+_32259655 0.527 BICD1
bicaudal D homolog 1 (Drosophila)
chr5_+_32173481 0.526 LOC153546
uncharacterized LOC153546
chr17_-_63052816 0.525


chr3_-_123303836 0.523 NM_198402
PTPLB
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b
chr6_+_36562135 0.521 SRSF3
serine/arginine-rich splicing factor 3
chr3_+_119187782 0.519 NM_152305
POGLUT1
protein O-glucosyltransferase 1
chr6_+_106546736 0.518 NM_182907
PRDM1
PR domain containing 1, with ZNF domain

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.20 9.11e-28 GO:0044237 cellular metabolic process
1.26 1.59e-26 GO:0044260 cellular macromolecule metabolic process
1.10 1.93e-24 GO:0009987 cellular process
1.21 3.90e-21 GO:0043170 macromolecule metabolic process
1.16 7.06e-21 GO:0008152 metabolic process
1.17 3.35e-19 GO:0044238 primary metabolic process
1.37 6.97e-18 GO:0010467 gene expression
1.68 4.46e-16 GO:0016071 mRNA metabolic process
1.27 4.99e-16 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35 9.87e-15 GO:0016070 RNA metabolic process
1.23 1.74e-13 GO:0006807 nitrogen compound metabolic process
1.27 1.76e-13 GO:0044267 cellular protein metabolic process
1.23 2.16e-13 GO:0034641 cellular nitrogen compound metabolic process
1.72 1.13e-12 GO:0006397 mRNA processing
1.28 2.21e-12 GO:0090304 nucleic acid metabolic process
1.80 2.91e-12 GO:0008380 RNA splicing
1.53 1.60e-11 GO:0006396 RNA processing
1.91 2.95e-10 GO:0000375 RNA splicing, via transesterification reactions
1.91 8.99e-10 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.91 8.99e-10 GO:0000398 nuclear mRNA splicing, via spliceosome
1.20 4.07e-09 GO:0019538 protein metabolic process
1.21 9.57e-07 GO:0044249 cellular biosynthetic process
1.16 1.01e-06 GO:0071840 cellular component organization or biogenesis
1.36 1.05e-06 GO:0015031 protein transport
1.36 1.38e-06 GO:0045184 establishment of protein localization
1.32 1.84e-06 GO:0008104 protein localization
1.25 2.40e-06 GO:0034645 cellular macromolecule biosynthetic process
1.28 4.76e-06 GO:0033036 macromolecule localization
1.18 5.95e-06 GO:0048518 positive regulation of biological process
1.24 6.01e-06 GO:0009059 macromolecule biosynthetic process
1.29 9.42e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.16 1.07e-05 GO:0016043 cellular component organization
1.18 2.65e-05 GO:0009058 biosynthetic process
1.28 2.66e-05 GO:0044085 cellular component biogenesis
1.19 2.80e-05 GO:0048522 positive regulation of cellular process
1.69 5.03e-05 GO:0006457 protein folding
1.26 6.00e-05 GO:0051641 cellular localization
1.34 6.42e-05 GO:0046907 intracellular transport
1.26 7.26e-05 GO:0009893 positive regulation of metabolic process
1.20 8.89e-05 GO:0043412 macromolecule modification
1.27 1.01e-04 GO:0044248 cellular catabolic process
1.14 1.15e-04 GO:0051179 localization
1.26 1.75e-04 GO:0031325 positive regulation of cellular metabolic process
1.20 3.04e-04 GO:0006464 protein modification process
1.16 4.08e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.28 4.49e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.79 8.53e-04 GO:0006403 RNA localization
1.15 8.86e-04 GO:0006810 transport
1.14 1.07e-03 GO:0051234 establishment of localization
1.25 1.34e-03 GO:0051649 establishment of localization in cell
1.82 1.57e-03 GO:0051028 mRNA transport
1.28 1.91e-03 GO:0006351 transcription, DNA-dependent
1.44 2.49e-03 GO:0044419 interspecies interaction between organisms
1.34 2.54e-03 GO:0009057 macromolecule catabolic process
1.37 2.55e-03 GO:0044265 cellular macromolecule catabolic process
1.76 3.52e-03 GO:0050657 nucleic acid transport
1.76 3.52e-03 GO:0050658 RNA transport
1.76 3.52e-03 GO:0051236 establishment of RNA localization
1.25 3.95e-03 GO:0010941 regulation of cell death
1.25 4.14e-03 GO:0022607 cellular component assembly
1.07 4.67e-03 GO:0065007 biological regulation
1.69 5.41e-03 GO:0006184 GTP catabolic process
1.16 8.22e-03 GO:0048523 negative regulation of cellular process
1.14 8.92e-03 GO:0071842 cellular component organization at cellular level
1.24 9.01e-03 GO:0043067 regulation of programmed cell death
1.07 9.12e-03 GO:0050794 regulation of cellular process
1.24 9.60e-03 GO:0032268 regulation of cellular protein metabolic process
1.24 1.08e-02 GO:0042981 regulation of apoptosis
1.25 1.21e-02 GO:0032774 RNA biosynthetic process
1.39 1.30e-02 GO:0016032 viral reproduction
1.23 1.32e-02 GO:0051246 regulation of protein metabolic process
1.28 1.35e-02 GO:0016192 vesicle-mediated transport
2.10 1.39e-02 GO:0006521 regulation of cellular amino acid metabolic process
1.63 1.58e-02 GO:0046039 GTP metabolic process
1.43 1.62e-02 GO:0043632 modification-dependent macromolecule catabolic process
1.29 1.88e-02 GO:0065003 macromolecular complex assembly
1.39 1.92e-02 GO:0032270 positive regulation of cellular protein metabolic process
1.20 1.99e-02 GO:0009056 catabolic process
1.12 2.25e-02 GO:0060255 regulation of macromolecule metabolic process
1.38 2.62e-02 GO:0051247 positive regulation of protein metabolic process
1.27 2.78e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.14 2.94e-02 GO:0048519 negative regulation of biological process
1.11 3.33e-02 GO:0031323 regulation of cellular metabolic process
1.42 3.42e-02 GO:0019941 modification-dependent protein catabolic process
1.38 3.76e-02 GO:0006886 intracellular protein transport
1.53 3.86e-02 GO:0022613 ribonucleoprotein complex biogenesis
1.65 3.87e-02 GO:0022900 electron transport chain
1.11 4.22e-02 GO:0080090 regulation of primary metabolic process
1.28 4.55e-02 GO:0051254 positive regulation of RNA metabolic process
1.40 4.89e-02 GO:0044257 cellular protein catabolic process
1.40 4.91e-02 GO:0051603 proteolysis involved in cellular protein catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 3.06e-36 GO:0005737 cytoplasm
1.12 1.53e-35 GO:0044424 intracellular part
1.11 1.05e-33 GO:0005622 intracellular
1.14 1.90e-27 GO:0043227 membrane-bounded organelle
1.14 5.10e-27 GO:0043231 intracellular membrane-bounded organelle
1.12 2.22e-26 GO:0043226 organelle
1.12 9.14e-26 GO:0043229 intracellular organelle
1.20 4.70e-25 GO:0044422 organelle part
1.20 6.97e-25 GO:0044446 intracellular organelle part
1.18 7.26e-23 GO:0044444 cytoplasmic part
1.25 9.97e-21 GO:0032991 macromolecular complex
1.32 1.74e-19 GO:0031974 membrane-enclosed lumen
1.32 7.16e-19 GO:0043233 organelle lumen
1.32 1.65e-18 GO:0070013 intracellular organelle lumen
1.31 4.64e-17 GO:0044428 nuclear part
1.31 7.43e-14 GO:0031981 nuclear lumen
1.04 6.26e-12 GO:0044464 cell part
1.04 6.94e-12 GO:0005623 cell
1.14 9.50e-12 GO:0005634 nucleus
1.34 3.07e-11 GO:0005654 nucleoplasm
1.21 1.50e-10 GO:0043234 protein complex
1.49 1.37e-08 GO:0030529 ribonucleoprotein complex
1.21 6.53e-07 GO:0005829 cytosol
1.20 1.26e-06 GO:0031090 organelle membrane
1.37 1.41e-06 GO:0044451 nucleoplasm part
1.29 9.88e-06 GO:0005794 Golgi apparatus
1.82 1.24e-05 GO:0005681 spliceosomal complex
1.14 4.32e-04 GO:0043228 non-membrane-bounded organelle
1.14 4.32e-04 GO:0043232 intracellular non-membrane-bounded organelle
2.05 7.54e-04 GO:0000502 proteasome complex
1.43 8.32e-04 GO:0048471 perinuclear region of cytoplasm
1.29 8.40e-04 GO:0031988 membrane-bounded vesicle
1.28 8.55e-04 GO:0031982 vesicle
1.19 8.88e-04 GO:0012505 endomembrane system
1.29 1.20e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.91 1.36e-03 GO:0071013 catalytic step 2 spliceosome
1.29 1.62e-03 GO:0031975 envelope
1.52 1.67e-03 GO:0016604 nuclear body
1.29 1.76e-03 GO:0031967 organelle envelope
1.34 1.98e-03 GO:0005730 nucleolus
1.27 2.21e-03 GO:0031410 cytoplasmic vesicle
1.22 3.83e-03 GO:0005783 endoplasmic reticulum
1.19 5.22e-03 GO:0005739 mitochondrion
1.48 5.37e-03 GO:0000785 chromatin
1.67 6.33e-03 GO:0044455 mitochondrial membrane part
2.21 8.47e-03 GO:0005747 mitochondrial respiratory chain complex I
2.21 8.47e-03 GO:0030964 NADH dehydrogenase complex
2.21 8.47e-03 GO:0045271 respiratory chain complex I
1.29 1.56e-02 GO:0005694 chromosome
1.91 2.06e-02 GO:0000786 nucleosome
1.31 2.30e-02 GO:0044427 chromosomal part
1.27 2.81e-02 GO:0044431 Golgi apparatus part
1.85 3.03e-02 GO:0070469 respiratory chain
1.88 3.17e-02 GO:0005746 mitochondrial respiratory chain

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 7.82e-31 GO:0005515 protein binding
1.08 1.56e-16 GO:0005488 binding
1.45 5.42e-12 GO:0003723 RNA binding
1.23 6.98e-10 GO:0000166 nucleotide binding
1.43 3.96e-04 GO:0000988 protein binding transcription factor activity
1.43 3.96e-04 GO:0000989 transcription factor binding transcription factor activity
1.43 5.79e-04 GO:0003712 transcription cofactor activity
1.17 2.15e-03 GO:0032553 ribonucleotide binding
1.17 2.15e-03 GO:0032555 purine ribonucleotide binding
1.17 2.34e-03 GO:0035639 purine ribonucleoside triphosphate binding
2.25 2.40e-03 GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
1.17 2.79e-03 GO:0017076 purine nucleotide binding
2.32 3.89e-03 GO:0003954 NADH dehydrogenase activity
2.32 3.89e-03 GO:0008137 NADH dehydrogenase (ubiquinone) activity
2.32 3.89e-03 GO:0050136 NADH dehydrogenase (quinone) activity
1.71 6.67e-03 GO:0051082 unfolded protein binding