Motif ID: ZBTB6.p2

Z-value: 1.069


Transcription factors associated with ZBTB6.p2:

Gene SymbolEntrez IDGene Name
ZBTB6 10773 zinc finger and BTB domain containing 6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
ZBTB6chr9_-_125675571-0.009.9e-01Click!


Activity profile for motif ZBTB6.p2.

activity profile for motif ZBTB6.p2


Sorted Z-values histogram for motif ZBTB6.p2

Sorted Z-values for motif ZBTB6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_101361688 1.338 SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr1_-_205290756 1.320 NM_030952
 NUAK2
NUAK family, SNF1-like kinase, 2
chr9_-_123691442 1.214 NM_001190945
 TRAF1
TNF receptor-associated factor 1
chr11_-_615649 1.063 NM_004031
 IRF7
interferon regulatory factor 7
chr1_+_101361649 1.059 SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr11_-_615920 1.059 IRF7
interferon regulatory factor 7
chr11_-_615998 1.004 NM_001572
NM_004029
 IRF7

interferon regulatory factor 7

chr6_-_33168448 0.951 RXRB
retinoid X receptor, beta
chr8_+_63161499 0.920 NM_173688
 NKAIN3
Na+/K+ transporting ATPase interacting 3
chrX_+_117480416 0.884 WDR44
WD repeat domain 44
chr12_+_130822590 0.736 PIWIL1
piwi-like 1 (Drosophila)
chr17_-_7518124 0.712 NM_004860
 FXR2
fragile X mental retardation, autosomal homolog 2
chr6_+_14118002 0.665 CD83
CD83 molecule
chr12_+_7942025 0.626 NANOG
Nanog homeobox
chr5_-_149682447 0.608 NM_001012301
 ARSI
arylsulfatase family, member I
chr10_+_23983674 0.585 NM_001098500
 KIAA1217
KIAA1217
chr2_-_233352530 0.579 NM_004826
 ECEL1
endothelin converting enzyme-like 1
chr20_+_6748744 0.577 NM_001200
 BMP2
bone morphogenetic protein 2
chr15_+_89182038 0.551 NM_002201
 ISG20
interferon stimulated exonuclease gene 20kDa
chr12_-_52914080 0.542 NM_000424
 KRT5
keratin 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 67 entries
enrichment   p-value GO term description
2.89 1.74e-02 GO:0060070 canonical Wnt receptor signaling pathway
2.02 8.02e-03 GO:0006486 protein glycosylation
2.02 8.02e-03 GO:0043413 macromolecule glycosylation
2.00 9.62e-03 GO:0070085 glycosylation
1.71 2.68e-02 GO:0051130 positive regulation of cellular component organization
1.70 2.86e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.67 4.38e-02 GO:0060284 regulation of cell development
1.65 1.72e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.59 2.68e-02 GO:0007409 axonogenesis
1.58 3.17e-02 GO:0032583 regulation of gene-specific transcription
1.57 1.54e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.57 3.51e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.55 1.75e-02 GO:0007417 central nervous system development
1.55 2.47e-02 GO:0000904 cell morphogenesis involved in differentiation
1.53 9.74e-04 GO:0030182 neuron differentiation
1.52 2.51e-03 GO:0010628 positive regulation of gene expression
1.52 7.19e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.52 1.74e-02 GO:0048666 neuron development
1.51 4.14e-05 GO:0048468 cell development
1.51 1.09e-04 GO:0048699 generation of neurons

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.44 2.87e-02 GO:0032580 Golgi cisterna membrane
1.64 8.40e-04 GO:0045202 synapse
1.58 9.30e-03 GO:0009986 cell surface
1.08 4.97e-02 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
1.61 4.66e-02 GO:0022836 gated channel activity
1.60 2.04e-03 GO:0004674 protein serine/threonine kinase activity
1.55 2.61e-02 GO:0005216 ion channel activity
1.53 4.66e-02 GO:0022838 substrate-specific channel activity
1.51 1.28e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.50 2.09e-03 GO:0004672 protein kinase activity
1.47 5.00e-04 GO:0016301 kinase activity
1.43 2.03e-04 GO:0001071 nucleic acid binding transcription factor activity
1.43 2.03e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.41 2.86e-02 GO:0043565 sequence-specific DNA binding
1.39 5.83e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.34 1.97e-02 GO:0030528 transcription regulator activity
1.18 1.01e-10 GO:0005515 protein binding
1.06 7.59e-03 GO:0005488 binding