Motif ID: ZEB1.p2

Z-value: 1.052


Transcription factors associated with ZEB1.p2:

Gene SymbolEntrez IDGene Name
ZEB1 6935 zinc finger E-box binding homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
ZEB1chr10_+_316080970.087.1e-01Click!


Activity profile for motif ZEB1.p2.

activity profile for motif ZEB1.p2


Sorted Z-values histogram for motif ZEB1.p2

Sorted Z-values for motif ZEB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZEB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr21_+_46293925 3.500


chr17_-_31204071 3.038 MYO1D
myosin ID
chr7_-_22396511 2.919 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr19_+_10381763 2.250 ICAM1
intercellular adhesion molecule 1
chr19_+_38755238 2.182 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755097 2.159 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr19_+_38755422 2.081 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr15_+_67358194 1.721 NM_005902
SMAD3
SMAD family member 3
chr1_-_209979388 1.622 NM_001206696
NM_006147
IRF6

interferon regulatory factor 6

chr14_-_51134862 1.438 SAV1
salvador homolog 1 (Drosophila)
chr14_-_51135021 1.431 NM_021818
SAV1
salvador homolog 1 (Drosophila)
chr1_-_95007139 1.413 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr1_+_37940180 1.338 ZC3H12A
zinc finger CCCH-type containing 12A
chr19_-_50432731 1.324 NUP62
nucleoporin 62kDa
chr1_+_37940129 1.276 ZC3H12A
zinc finger CCCH-type containing 12A
chr1_+_37940074 1.229 NM_025079
ZC3H12A
zinc finger CCCH-type containing 12A
chr16_+_84733606 1.218 USP10
ubiquitin specific peptidase 10
chr18_+_59992519 1.200 NM_003839
TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr3_+_30648372 1.168 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr5_+_139028483 1.166 CXXC5
CXXC finger protein 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.16 3.96e-02 GO:0048856 anatomical structure development
1.08 1.73e-05 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
3.00 1.34e-02 GO:0001725 stress fiber
2.80 3.87e-02 GO:0032432 actin filament bundle
2.71 3.57e-02 GO:0042641 actomyosin
1.84 4.71e-03 GO:0005912 adherens junction
1.73 2.11e-02 GO:0070161 anchoring junction
1.66 5.30e-03 GO:0016323 basolateral plasma membrane
1.59 1.30e-02 GO:0000323 lytic vacuole
1.59 1.30e-02 GO:0005764 lysosome
1.58 5.68e-03 GO:0015629 actin cytoskeleton
1.51 3.20e-02 GO:0005773 vacuole
1.43 1.64e-03 GO:0030054 cell junction
1.36 1.14e-02 GO:0031967 organelle envelope
1.34 2.10e-02 GO:0031975 envelope
1.23 3.79e-04 GO:0005829 cytosol
1.19 2.68e-02 GO:0031090 organelle membrane
1.18 5.49e-20 GO:0005737 cytoplasm
1.18 7.70e-11 GO:0044444 cytoplasmic part
1.18 3.88e-02 GO:0044459 plasma membrane part
1.14 6.93e-05 GO:0044446 intracellular organelle part
1.13 1.07e-04 GO:0044422 organelle part

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.09 9.52e-03 GO:0005088 Ras guanyl-nucleotide exchange factor activity
1.79 1.18e-02 GO:0005085 guanyl-nucleotide exchange factor activity
1.15 1.24e-10 GO:0005515 protein binding