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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for AACACUG

Z-value: 0.82

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miRNA associated with seed AACACUG

NamemiRBASE accession
hsa-miR-141-3p
MIMAT0000432
hsa-miR-200a-3p
MIMAT0000682

Activity profile of AACACUG motif

Sorted Z-values of AACACUG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_84543734 3.38 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr3_+_39851094 2.91 ENST00000302541.6
MYRIP
myosin VIIA and Rab interacting protein
chr10_-_81205373 2.85 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr4_-_186877502 2.62 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2
sorbin and SH3 domain containing 2
chr6_-_16761678 2.45 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr1_+_61547894 2.45 ENST00000403491.3
NFIA
nuclear factor I/A
chr12_-_42877764 2.06 ENST00000455697.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr10_-_33623564 2.04 ENST00000374875.1
ENST00000374822.4
NRP1
neuropilin 1
chr17_+_68165657 1.87 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr17_-_8534067 1.81 ENST00000360416.3
ENST00000269243.4
MYH10
myosin, heavy chain 10, non-muscle
chr11_+_86748863 1.76 ENST00000340353.7
TMEM135
transmembrane protein 135
chr7_-_132261253 1.69 ENST00000321063.4
PLXNA4
plexin A4
chr10_+_112631547 1.45 ENST00000280154.7
ENST00000393104.2
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr14_+_53019822 1.34 ENST00000321662.6
GPR137C
G protein-coupled receptor 137C
chr2_+_45878790 1.34 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr1_-_211752073 1.25 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr6_+_107811162 1.18 ENST00000317357.5
SOBP
sine oculis binding protein homolog (Drosophila)
chr2_-_152684977 1.16 ENST00000428992.2
ENST00000295087.8
ARL5A
ADP-ribosylation factor-like 5A
chr11_-_2158507 1.13 ENST00000381392.1
ENST00000381395.1
ENST00000418738.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr3_+_43328004 1.12 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNRK
SNF related kinase
chr14_-_30396948 1.05 ENST00000331968.5
PRKD1
protein kinase D1
chr2_-_240322643 1.03 ENST00000345617.3
HDAC4
histone deacetylase 4
chr2_-_160472952 1.00 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr13_-_77460525 0.99 ENST00000377474.2
ENST00000317765.2
KCTD12
potassium channel tetramerization domain containing 12
chr14_-_90085458 0.97 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr2_-_86094764 0.93 ENST00000393808.3
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr4_+_87856129 0.93 ENST00000395146.4
ENST00000507468.1
AFF1
AF4/FMR2 family, member 1
chr1_+_178694300 0.91 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr9_+_90112741 0.89 ENST00000469640.2
DAPK1
death-associated protein kinase 1
chr8_-_89339705 0.89 ENST00000286614.6
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr4_-_83719983 0.85 ENST00000319540.4
SCD5
stearoyl-CoA desaturase 5
chr10_+_8096631 0.85 ENST00000379328.3
GATA3
GATA binding protein 3
chr7_-_11871815 0.84 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr22_-_28197486 0.84 ENST00000302326.4
MN1
meningioma (disrupted in balanced translocation) 1
chr8_-_127570603 0.83 ENST00000304916.3
FAM84B
family with sequence similarity 84, member B
chr6_+_1610681 0.81 ENST00000380874.2
FOXC1
forkhead box C1
chr8_-_71316021 0.81 ENST00000452400.2
NCOA2
nuclear receptor coactivator 2
chr22_-_29075853 0.80 ENST00000397906.2
TTC28
tetratricopeptide repeat domain 28
chr3_+_25469724 0.80 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr1_+_93913713 0.80 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr13_-_110438914 0.78 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr4_-_42659102 0.78 ENST00000264449.10
ENST00000510289.1
ENST00000381668.5
ATP8A1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr3_+_44626446 0.78 ENST00000441021.1
ENST00000322734.2
ZNF660
zinc finger protein 660
chr15_+_57210818 0.77 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
TCF12
transcription factor 12
chr4_-_85887503 0.76 ENST00000509172.1
ENST00000322366.6
ENST00000295888.4
ENST00000502713.1
WDFY3
WD repeat and FYVE domain containing 3
chr4_+_144257915 0.75 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr12_+_96588143 0.75 ENST00000228741.3
ENST00000547249.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr9_+_131644388 0.74 ENST00000372600.4
LRRC8A
leucine rich repeat containing 8 family, member A
chr11_-_73309228 0.73 ENST00000356467.4
ENST00000064778.4
FAM168A
family with sequence similarity 168, member A
chr5_-_172198190 0.73 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr18_+_13218769 0.71 ENST00000399848.3
ENST00000361205.4
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr19_-_31840438 0.70 ENST00000240587.4
TSHZ3
teashirt zinc finger homeobox 3
chr22_+_40573921 0.69 ENST00000454349.2
ENST00000335727.9
TNRC6B
trinucleotide repeat containing 6B
chr6_+_17600576 0.68 ENST00000259963.3
FAM8A1
family with sequence similarity 8, member A1
chr11_-_82782861 0.68 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30
RAB30, member RAS oncogene family
chr3_-_171178157 0.66 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TNIK
TRAF2 and NCK interacting kinase
chr2_+_179059365 0.66 ENST00000190611.4
OSBPL6
oxysterol binding protein-like 6
chr11_-_67888671 0.65 ENST00000265689.4
CHKA
choline kinase alpha
chr6_+_17281573 0.63 ENST00000379052.5
RBM24
RNA binding motif protein 24
chr3_-_72496035 0.62 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr12_-_46766577 0.61 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr13_+_80055284 0.60 ENST00000218652.7
NDFIP2
Nedd4 family interacting protein 2
chr11_+_134094508 0.59 ENST00000281187.5
ENST00000525095.2
VPS26B
vacuolar protein sorting 26 homolog B (S. pombe)
chr10_+_70320413 0.58 ENST00000373644.4
TET1
tet methylcytosine dioxygenase 1
chr2_+_198669365 0.58 ENST00000428675.1
PLCL1
phospholipase C-like 1
chr2_-_218808771 0.58 ENST00000449814.1
ENST00000171887.4
TNS1
tensin 1
chr16_+_53088885 0.56 ENST00000566029.1
ENST00000447540.1
CHD9
chromodomain helicase DNA binding protein 9
chr9_-_16870704 0.56 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chr10_+_65281123 0.55 ENST00000298249.4
ENST00000373758.4
REEP3
receptor accessory protein 3
chr10_+_89622870 0.54 ENST00000371953.3
PTEN
phosphatase and tensin homolog
chr2_+_148778570 0.54 ENST00000407073.1
MBD5
methyl-CpG binding domain protein 5
chr5_-_43313574 0.53 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr3_+_158991025 0.52 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr8_-_81787006 0.51 ENST00000327835.3
ZNF704
zinc finger protein 704
chr10_+_76586348 0.50 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B
K(lysine) acetyltransferase 6B
chr12_-_56727487 0.50 ENST00000548043.1
ENST00000425394.2
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr5_+_10353780 0.49 ENST00000449913.2
ENST00000503788.1
ENST00000274140.5
MARCH6
membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
chr21_+_35445827 0.49 ENST00000608209.1
ENST00000381151.3
SLC5A3
SLC5A3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr6_-_52441713 0.49 ENST00000182527.3
TRAM2
translocation associated membrane protein 2
chr18_-_53255766 0.48 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr3_+_159557637 0.48 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr1_+_82266053 0.48 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr9_+_4490394 0.48 ENST00000262352.3
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr3_+_61547585 0.48 ENST00000295874.10
ENST00000474889.1
PTPRG
protein tyrosine phosphatase, receptor type, G
chr3_+_152017181 0.48 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1
muscleblind-like splicing regulator 1
chrX_-_119694538 0.47 ENST00000371322.5
CUL4B
cullin 4B
chr12_+_125478241 0.47 ENST00000341446.8
BRI3BP
BRI3 binding protein
chr12_+_12938541 0.46 ENST00000356591.4
APOLD1
apolipoprotein L domain containing 1
chr6_+_53659746 0.45 ENST00000370888.1
LRRC1
leucine rich repeat containing 1
chr7_-_156685890 0.45 ENST00000353442.5
LMBR1
limb development membrane protein 1
chr10_-_65225722 0.45 ENST00000399251.1
JMJD1C
jumonji domain containing 1C
chr10_-_64576105 0.45 ENST00000242480.3
ENST00000411732.1
EGR2
early growth response 2
chr3_-_112360116 0.45 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr12_+_48516357 0.44 ENST00000549022.1
ENST00000547587.1
ENST00000312352.7
PFKM
phosphofructokinase, muscle
chr19_-_33555780 0.43 ENST00000254260.3
ENST00000400226.4
RHPN2
rhophilin, Rho GTPase binding protein 2
chr3_-_56502375 0.43 ENST00000288221.6
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr2_+_169312350 0.43 ENST00000305747.6
CERS6
ceramide synthase 6
chr14_+_36295504 0.43 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like
chr14_-_77495007 0.42 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr5_+_172483347 0.42 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF
CREB3 regulatory factor
chr12_-_109125285 0.41 ENST00000552871.1
ENST00000261401.3
CORO1C
coronin, actin binding protein, 1C
chr2_+_178257372 0.41 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr6_+_32121218 0.41 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
PPT2
palmitoyl-protein thioesterase 2
chr12_+_50898881 0.39 ENST00000301180.5
DIP2B
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chrX_+_21857717 0.39 ENST00000379484.5
MBTPS2
membrane-bound transcription factor peptidase, site 2
chr21_-_44846999 0.39 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr13_+_42846272 0.39 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr17_-_49337392 0.38 ENST00000376381.2
ENST00000586178.1
MBTD1
mbt domain containing 1
chr11_+_101981169 0.38 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
YAP1
Yes-associated protein 1
chr20_+_57226284 0.37 ENST00000458280.1
ENST00000355957.5
ENST00000361770.5
ENST00000312283.8
ENST00000412911.1
ENST00000359617.4
ENST00000371141.4
STX16
syntaxin 16
chr1_-_28969517 0.37 ENST00000263974.4
ENST00000373824.4
TAF12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr11_+_33563821 0.37 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr12_-_96794143 0.37 ENST00000543119.2
CDK17
cyclin-dependent kinase 17
chr14_-_35182994 0.36 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr9_-_74980113 0.36 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5
zinc finger, AN1-type domain 5
chr5_-_148930960 0.36 ENST00000261798.5
ENST00000377843.2
CSNK1A1
casein kinase 1, alpha 1
chr7_+_8008418 0.36 ENST00000223145.5
GLCCI1
glucocorticoid induced transcript 1
chr21_+_18885430 0.36 ENST00000356275.6
ENST00000400165.1
ENST00000400169.1
ENST00000306618.10
CXADR
coxsackie virus and adenovirus receptor
chr20_+_10199468 0.35 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr15_-_52821247 0.35 ENST00000399231.3
ENST00000399233.2
MYO5A
myosin VA (heavy chain 12, myoxin)
chr10_-_62704005 0.35 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr8_-_95908902 0.33 ENST00000520509.1
CCNE2
cyclin E2
chr17_+_66508537 0.33 ENST00000392711.1
ENST00000585427.1
ENST00000589228.1
ENST00000536854.2
ENST00000588702.1
ENST00000589309.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr10_-_126849068 0.33 ENST00000494626.2
ENST00000337195.5
CTBP2
C-terminal binding protein 2
chr17_-_46178527 0.33 ENST00000393408.3
CBX1
chromobox homolog 1
chr1_-_91487013 0.33 ENST00000347275.5
ENST00000370440.1
ZNF644
zinc finger protein 644
chr17_-_37557846 0.32 ENST00000394294.3
ENST00000583610.1
ENST00000264658.6
FBXL20
F-box and leucine-rich repeat protein 20
chr7_+_107220422 0.32 ENST00000005259.4
BCAP29
B-cell receptor-associated protein 29
chr17_+_61086917 0.32 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr11_+_117049445 0.32 ENST00000324225.4
ENST00000532960.1
SIDT2
SID1 transmembrane family, member 2
chr6_+_167412665 0.31 ENST00000366847.4
FGFR1OP
FGFR1 oncogene partner
chr1_+_20208870 0.31 ENST00000375120.3
OTUD3
OTU domain containing 3
chr12_+_60083118 0.30 ENST00000261187.4
ENST00000543448.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr3_-_114790179 0.30 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr17_+_28705921 0.30 ENST00000225719.4
CPD
carboxypeptidase D
chr9_-_124989804 0.30 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr10_+_63661053 0.29 ENST00000279873.7
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr17_-_202579 0.29 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
RPH3AL
rabphilin 3A-like (without C2 domains)
chr17_-_19771216 0.29 ENST00000395544.4
ULK2
unc-51 like autophagy activating kinase 2
chr9_-_98279241 0.29 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
PTCH1
patched 1
chr3_+_152552685 0.29 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr9_-_123476719 0.28 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr6_-_122792919 0.28 ENST00000339697.4
SERINC1
serine incorporator 1
chr7_-_27224795 0.28 ENST00000006015.3
HOXA11
homeobox A11
chr11_+_113930291 0.27 ENST00000335953.4
ZBTB16
zinc finger and BTB domain containing 16
chr4_+_159690218 0.27 ENST00000264433.6
FNIP2
folliculin interacting protein 2
chr22_+_38201114 0.27 ENST00000340857.2
H1F0
H1 histone family, member 0
chr3_-_33686743 0.27 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr17_-_74137374 0.27 ENST00000322957.6
FOXJ1
forkhead box J1
chr10_-_94333784 0.27 ENST00000265986.6
IDE
insulin-degrading enzyme
chr7_+_99613195 0.26 ENST00000324306.6
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr7_-_105517021 0.26 ENST00000318724.4
ENST00000419735.3
ATXN7L1
ataxin 7-like 1
chr1_+_244214577 0.26 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr20_+_277737 0.26 ENST00000382352.3
ZCCHC3
zinc finger, CCHC domain containing 3
chr9_-_36400213 0.26 ENST00000259605.6
ENST00000353739.4
RNF38
ring finger protein 38
chr5_-_95158375 0.26 ENST00000512469.2
ENST00000379979.4
ENST00000505427.1
ENST00000508780.1
GLRX
glutaredoxin (thioltransferase)
chr9_+_130374537 0.25 ENST00000373302.3
ENST00000373299.1
STXBP1
syntaxin binding protein 1
chr4_+_86396265 0.25 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr14_-_31676964 0.25 ENST00000553700.1
HECTD1
HECT domain containing E3 ubiquitin protein ligase 1
chrX_+_51928002 0.25 ENST00000375626.3
MAGED4
melanoma antigen family D, 4
chr12_-_104532062 0.25 ENST00000240055.3
NFYB
nuclear transcription factor Y, beta
chr1_-_171711387 0.25 ENST00000236192.7
VAMP4
vesicle-associated membrane protein 4
chr1_+_93544791 0.25 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
MTF2
metal response element binding transcription factor 2
chr17_+_38278530 0.25 ENST00000398532.4
MSL1
male-specific lethal 1 homolog (Drosophila)
chr1_+_87380299 0.24 ENST00000370551.4
ENST00000370550.5
HS2ST1
heparan sulfate 2-O-sulfotransferase 1
chr12_+_14518598 0.24 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
ATF7IP
activating transcription factor 7 interacting protein
chr14_-_57735528 0.24 ENST00000340918.7
ENST00000413566.2
EXOC5
exocyst complex component 5
chr3_+_14989076 0.24 ENST00000413118.1
ENST00000425241.1
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr1_+_211433275 0.24 ENST00000367005.4
RCOR3
REST corepressor 3
chrX_+_118370211 0.24 ENST00000217971.7
PGRMC1
progesterone receptor membrane component 1
chr1_+_200708671 0.24 ENST00000358823.2
CAMSAP2
calmodulin regulated spectrin-associated protein family, member 2
chrX_-_50557014 0.24 ENST00000376020.2
SHROOM4
shroom family member 4
chr13_+_33160553 0.23 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr1_-_231560790 0.23 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr4_-_16228120 0.23 ENST00000405303.2
TAPT1
transmembrane anterior posterior transformation 1
chr13_-_30881621 0.23 ENST00000380615.3
KATNAL1
katanin p60 subunit A-like 1
chr1_-_179198702 0.22 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr10_+_69644404 0.22 ENST00000212015.6
SIRT1
sirtuin 1
chr7_+_100136811 0.22 ENST00000300176.4
ENST00000262935.4
AGFG2
ArfGAP with FG repeats 2
chr2_+_138721850 0.22 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr9_-_123555655 0.22 ENST00000340778.5
ENST00000453291.1
ENST00000608872.1
FBXW2
F-box and WD repeat domain containing 2
chr14_+_100705322 0.21 ENST00000262238.4
YY1
YY1 transcription factor
chr5_+_118407053 0.21 ENST00000311085.8
ENST00000539542.1
DMXL1
Dmx-like 1
chr1_-_225840747 0.20 ENST00000366843.2
ENST00000366844.3
ENAH
enabled homolog (Drosophila)
chr15_-_85259330 0.20 ENST00000560266.1
SEC11A
SEC11 homolog A (S. cerevisiae)
chr9_-_6015607 0.20 ENST00000259569.5
RANBP6
RAN binding protein 6
chr15_+_77712993 0.20 ENST00000336216.4
ENST00000381714.3
ENST00000558651.1
HMG20A
high mobility group 20A
chr1_+_220701456 0.19 ENST00000366918.4
ENST00000402574.1
MARK1
MAP/microtubule affinity-regulating kinase 1
chr20_-_4982132 0.19 ENST00000338244.1
ENST00000424750.2
SLC23A2
solute carrier family 23 (ascorbic acid transporter), member 2
chr2_+_113403434 0.19 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr19_-_2702681 0.19 ENST00000382159.3
GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr5_+_53813536 0.18 ENST00000343017.6
ENST00000381410.4
ENST00000326277.3
SNX18
sorting nexin 18
chr10_+_112404132 0.18 ENST00000369519.3
RBM20
RNA binding motif protein 20
chr17_-_62502639 0.18 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr3_+_5229356 0.18 ENST00000256497.4
EDEM1
ER degradation enhancer, mannosidase alpha-like 1
chr2_+_46926048 0.17 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr11_-_74109422 0.17 ENST00000298198.4
PGM2L1
phosphoglucomutase 2-like 1
chr17_+_36584662 0.17 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr21_-_39870339 0.17 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr8_-_95961578 0.17 ENST00000448464.2
ENST00000342697.4
TP53INP1
tumor protein p53 inducible nuclear protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of AACACUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.5 1.6 GO:0036446 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.5 2.1 GO:2000691 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.5 3.4 GO:0097338 response to clozapine(GO:0097338)
0.5 1.9 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.4 1.3 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.4 1.7 GO:0021592 fourth ventricle development(GO:0021592)
0.4 2.0 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.3 0.9 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.3 4.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.2 0.9 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.2 0.9 GO:0061290 pro-T cell differentiation(GO:0002572) cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) negative regulation of DNA demethylation(GO:1901536)
0.2 0.8 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.2 0.6 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.2 1.3 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.2 0.8 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.2 1.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.4 GO:0035284 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.6 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.4 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.4 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.5 GO:1903984 negative regulation of ribosome biogenesis(GO:0090071) regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.8 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 1.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.4 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.8 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 1.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.4 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.5 GO:0000101 sulfur amino acid transport(GO:0000101)
0.1 2.4 GO:0072189 ureter development(GO:0072189)
0.1 0.3 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.5 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.3 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 0.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.3 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.8 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.8 GO:0035973 aggrephagy(GO:0035973)
0.1 0.3 GO:0007412 axon target recognition(GO:0007412) regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 1.9 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.4 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.5 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.4 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.1 0.5 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.7 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 0.6 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 2.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.4 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.1 0.4 GO:0006789 bilirubin conjugation(GO:0006789)
0.1 0.6 GO:0032328 alanine transport(GO:0032328)
0.1 0.1 GO:0060067 cervix development(GO:0060067)
0.1 0.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.2 GO:0070904 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.5 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 0.4 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 0.3 GO:0060406 positive regulation of penile erection(GO:0060406)
0.1 0.3 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 1.1 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 0.7 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.4 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.4 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.0 0.3 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 1.8 GO:0032094 response to food(GO:0032094)
0.0 0.9 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.4 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.0 0.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.7 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.2 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425)
0.0 0.2 GO:0051344 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.3 GO:0035873 pyruvate transport(GO:0006848) lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.7 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.6 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.5 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372) cellular response to cholesterol(GO:0071397)
0.0 0.3 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.2 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.1 GO:0048690 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.0 0.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.5 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.1 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.3 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0097491 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.6 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.6 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.2 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.1 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.3 GO:2000480 negative regulation of activated T cell proliferation(GO:0046007) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.0 GO:0090102 cochlea development(GO:0090102)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0016577 histone demethylation(GO:0016577)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.4 GO:0003016 respiratory system process(GO:0003016)
0.0 0.1 GO:0030836 positive regulation of actin filament depolymerization(GO:0030836)
0.0 0.8 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.2 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.2 GO:0010225 response to UV-C(GO:0010225)
0.0 0.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.0 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.0 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.6 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) regulation of rRNA processing(GO:2000232) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.0 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.4 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0097513 myosin II filament(GO:0097513)
0.4 2.5 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.3 3.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 3.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 2.8 GO:0031045 dense core granule(GO:0031045)
0.1 0.8 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.5 GO:0031251 PAN complex(GO:0031251)
0.1 0.6 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.1 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.5 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.1 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.5 GO:0016600 flotillin complex(GO:0016600)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 1.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.6 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 2.2 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 4.0 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 1.2 GO:0042734 presynaptic membrane(GO:0042734)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0034046 poly(G) binding(GO:0034046)
0.3 1.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.3 1.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 0.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.6 GO:0004103 choline kinase activity(GO:0004103)
0.2 1.0 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.2 2.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 0.8 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.2 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 3.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 0.9 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.5 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.5 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 1.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.8 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.2 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.9 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.3 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 3.6 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0005119 smoothened binding(GO:0005119)
0.0 1.1 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.0 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 1.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.5 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.0 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 1.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.5 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.4 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 1.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.9 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.6 PID EPO PATHWAY EPO signaling pathway
0.0 0.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.9 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.9 PID IL27 PATHWAY IL27-mediated signaling events
0.0 2.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.1 PID IGF1 PATHWAY IGF1 pathway
0.0 1.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.9 PID FOXO PATHWAY FoxO family signaling
0.0 0.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 2.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 1.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.8 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME MITOTIC G2 G2 M PHASES Genes involved in Mitotic G2-G2/M phases
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases