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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for AAGGUGC

Z-value: 0.44

Motif logo

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miRNA associated with seed AAGGUGC

NamemiRBASE accession
hsa-miR-18a-5p
MIMAT0000072
hsa-miR-18b-5p
MIMAT0001412
hsa-miR-4735-3p
MIMAT0019861

Activity profile of AAGGUGC motif

Sorted Z-values of AAGGUGC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_186877502 1.46 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2
sorbin and SH3 domain containing 2
chr2_+_12857015 1.14 ENST00000155926.4
TRIB2
tribbles pseudokinase 2
chr6_-_16761678 1.08 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr4_+_55524085 0.96 ENST00000412167.2
ENST00000288135.5
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr20_+_34700333 0.95 ENST00000441639.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr6_-_111136513 0.87 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr3_+_37903432 0.71 ENST00000443503.2
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr8_-_81787006 0.62 ENST00000327835.3
ZNF704
zinc finger protein 704
chr1_+_84543734 0.56 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_+_56111361 0.52 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr2_+_28615669 0.51 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr17_+_68165657 0.44 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr15_+_39873268 0.43 ENST00000397591.2
ENST00000260356.5
THBS1
thrombospondin 1
chr9_-_74383799 0.42 ENST00000377044.4
TMEM2
transmembrane protein 2
chr11_-_116968987 0.42 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK3
SIK family kinase 3
chr10_-_81205373 0.41 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr11_+_108093839 0.40 ENST00000452508.2
ATM
ataxia telangiectasia mutated
chr1_-_20812690 0.36 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr5_+_78532003 0.35 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr1_-_161993616 0.33 ENST00000294794.3
OLFML2B
olfactomedin-like 2B
chr1_+_173684047 0.31 ENST00000546011.1
ENST00000209884.4
KLHL20
kelch-like family member 20
chr4_-_42659102 0.29 ENST00000264449.10
ENST00000510289.1
ENST00000381668.5
ATP8A1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr1_-_95007193 0.25 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr12_-_56583332 0.25 ENST00000347471.4
ENST00000267064.4
ENST00000394023.3
SMARCC2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr15_-_34628951 0.25 ENST00000397707.2
ENST00000560611.1
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr11_+_94822968 0.25 ENST00000278505.4
ENDOD1
endonuclease domain containing 1
chr11_-_130184555 0.24 ENST00000525842.1
ZBTB44
zinc finger and BTB domain containing 44
chr18_+_20513782 0.24 ENST00000399722.2
ENST00000399725.2
ENST00000399721.2
ENST00000583594.1
RBBP8
retinoblastoma binding protein 8
chr19_+_3572925 0.24 ENST00000333651.6
ENST00000417382.1
ENST00000453933.1
ENST00000262949.7
HMG20B
high mobility group 20B
chr17_-_40306934 0.23 ENST00000592574.1
ENST00000550406.1
ENST00000547517.1
ENST00000393860.3
ENST00000346213.4
CTD-2132N18.3
RAB5C
Uncharacterized protein
RAB5C, member RAS oncogene family
chr6_+_138188551 0.23 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr8_+_142402089 0.23 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3
protein tyrosine phosphatase type IVA, member 3
chr12_+_5019061 0.22 ENST00000382545.3
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr19_+_1752372 0.22 ENST00000382349.4
ONECUT3
one cut homeobox 3
chr9_-_123639600 0.20 ENST00000373896.3
PHF19
PHD finger protein 19
chr3_+_43328004 0.20 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNRK
SNF related kinase
chr9_-_35563896 0.20 ENST00000399742.2
FAM166B
family with sequence similarity 166, member B
chr2_+_235860616 0.19 ENST00000392011.2
SH3BP4
SH3-domain binding protein 4
chr12_+_19592602 0.19 ENST00000398864.3
ENST00000266508.9
AEBP2
AE binding protein 2
chr3_-_114790179 0.19 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr15_-_61521495 0.18 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr9_+_125703282 0.18 ENST00000373647.4
ENST00000402311.1
RABGAP1
RAB GTPase activating protein 1
chr6_+_16238786 0.18 ENST00000259727.4
GMPR
guanosine monophosphate reductase
chrX_-_24045303 0.17 ENST00000328046.8
KLHL15
kelch-like family member 15
chr5_-_73937244 0.17 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr6_-_107436473 0.17 ENST00000369042.1
BEND3
BEN domain containing 3
chr12_+_11802753 0.17 ENST00000396373.4
ETV6
ets variant 6
chr12_+_56360550 0.15 ENST00000266970.4
CDK2
cyclin-dependent kinase 2
chr6_+_39760783 0.14 ENST00000398904.2
ENST00000538976.1
DAAM2
dishevelled associated activator of morphogenesis 2
chr1_-_228135599 0.14 ENST00000272164.5
WNT9A
wingless-type MMTV integration site family, member 9A
chr22_+_38093005 0.14 ENST00000406386.3
TRIOBP
TRIO and F-actin binding protein
chr16_-_17564738 0.13 ENST00000261381.6
XYLT1
xylosyltransferase I
chr14_+_103058948 0.13 ENST00000262241.6
RCOR1
REST corepressor 1
chr3_+_107241783 0.12 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
BBX
bobby sox homolog (Drosophila)
chr3_+_152017181 0.12 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1
muscleblind-like splicing regulator 1
chr6_-_132272504 0.12 ENST00000367976.3
CTGF
connective tissue growth factor
chr5_-_171711061 0.11 ENST00000393792.2
UBTD2
ubiquitin domain containing 2
chr12_+_109535373 0.11 ENST00000242576.2
UNG
uracil-DNA glycosylase
chr5_-_43313574 0.10 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr9_-_93405352 0.10 ENST00000375765.3
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr1_-_51425902 0.10 ENST00000396153.2
FAF1
Fas (TNFRSF6) associated factor 1
chr9_+_91003271 0.10 ENST00000375859.3
ENST00000541629.1
SPIN1
spindlin 1
chr3_-_185542817 0.09 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr19_+_50879705 0.09 ENST00000598168.1
ENST00000411902.2
ENST00000253727.5
ENST00000597790.1
ENST00000597130.1
ENST00000599105.1
NR1H2
nuclear receptor subfamily 1, group H, member 2
chr16_+_30960375 0.08 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3
ORAI calcium release-activated calcium modulator 3
chr19_-_36523709 0.08 ENST00000592017.1
ENST00000360535.4
CLIP3
CAP-GLY domain containing linker protein 3
chr8_+_28747884 0.08 ENST00000287701.10
ENST00000444075.1
ENST00000403668.2
ENST00000519662.1
ENST00000558662.1
ENST00000523613.1
ENST00000560599.1
ENST00000397358.3
HMBOX1
homeobox containing 1
chr22_+_40573921 0.08 ENST00000454349.2
ENST00000335727.9
TNRC6B
trinucleotide repeat containing 6B
chrX_+_150565653 0.08 ENST00000330374.6
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr6_-_99873145 0.08 ENST00000369239.5
ENST00000438806.1
PNISR
PNN-interacting serine/arginine-rich protein
chr16_-_57219966 0.08 ENST00000565760.1
ENST00000309137.8
ENST00000570184.1
ENST00000562324.1
FAM192A
family with sequence similarity 192, member A
chrX_-_19905703 0.08 ENST00000397821.3
SH3KBP1
SH3-domain kinase binding protein 1
chr6_-_11232891 0.08 ENST00000379433.5
ENST00000379446.5
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr6_+_152011628 0.07 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr4_+_183164574 0.07 ENST00000511685.1
TENM3
teneurin transmembrane protein 3
chr16_+_69599861 0.07 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr1_+_32573636 0.07 ENST00000373625.3
KPNA6
karyopherin alpha 6 (importin alpha 7)
chr2_+_24714729 0.06 ENST00000406961.1
ENST00000405141.1
NCOA1
nuclear receptor coactivator 1
chr4_+_154125565 0.06 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr9_-_127952032 0.06 ENST00000456642.1
ENST00000373546.3
ENST00000373547.4
PPP6C
protein phosphatase 6, catalytic subunit
chr5_+_122424816 0.06 ENST00000407847.4
PRDM6
PR domain containing 6
chr9_+_96338860 0.06 ENST00000375376.4
PHF2
PHD finger protein 2
chr19_-_46000251 0.05 ENST00000590526.1
ENST00000344680.4
ENST00000245923.4
RTN2
reticulon 2
chr17_-_7382834 0.05 ENST00000380599.4
ZBTB4
zinc finger and BTB domain containing 4
chr21_-_40685477 0.05 ENST00000342449.3
BRWD1
bromodomain and WD repeat domain containing 1
chr17_-_62340581 0.05 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
TEX2
testis expressed 2
chr7_+_66386204 0.05 ENST00000341567.4
ENST00000607045.1
TMEM248
transmembrane protein 248
chr17_+_48423453 0.05 ENST00000017003.2
ENST00000509778.1
ENST00000507602.1
XYLT2
xylosyltransferase II
chr1_+_87794150 0.05 ENST00000370544.5
LMO4
LIM domain only 4
chr16_-_85722530 0.04 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr20_+_43104508 0.04 ENST00000262605.4
ENST00000372904.3
TTPAL
tocopherol (alpha) transfer protein-like
chrX_+_13707235 0.04 ENST00000464506.1
RAB9A
RAB9A, member RAS oncogene family
chr2_+_46926048 0.04 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr6_-_53409890 0.04 ENST00000229416.6
GCLC
glutamate-cysteine ligase, catalytic subunit
chr16_-_74640986 0.04 ENST00000422840.2
ENST00000565260.1
ENST00000447066.2
ENST00000205061.5
GLG1
golgi glycoprotein 1
chr4_+_79697495 0.04 ENST00000502871.1
ENST00000335016.5
BMP2K
BMP2 inducible kinase
chr18_+_48086440 0.04 ENST00000400384.2
ENST00000540640.1
ENST00000592595.1
MAPK4
mitogen-activated protein kinase 4
chr2_-_201828356 0.03 ENST00000234296.2
ORC2
origin recognition complex, subunit 2
chr3_+_187930719 0.03 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr12_+_49212514 0.03 ENST00000301050.2
ENST00000548279.1
ENST00000547230.1
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr13_-_77601282 0.03 ENST00000355619.5
FBXL3
F-box and leucine-rich repeat protein 3
chr10_+_102295616 0.03 ENST00000299163.6
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr6_+_122720681 0.03 ENST00000368455.4
ENST00000452194.1
HSF2
heat shock transcription factor 2
chr9_-_99180597 0.02 ENST00000375256.4
ZNF367
zinc finger protein 367
chr16_+_71879861 0.02 ENST00000427980.2
ENST00000568581.1
ATXN1L
IST1
ataxin 1-like
increased sodium tolerance 1 homolog (yeast)
chr7_+_90225796 0.02 ENST00000380050.3
CDK14
cyclin-dependent kinase 14
chr12_-_44200052 0.02 ENST00000548315.1
ENST00000552521.1
ENST00000546662.1
ENST00000548403.1
ENST00000546506.1
TWF1
twinfilin actin-binding protein 1
chr4_+_6784401 0.02 ENST00000425103.1
ENST00000307659.5
KIAA0232
KIAA0232
chr20_+_277737 0.02 ENST00000382352.3
ZCCHC3
zinc finger, CCHC domain containing 3
chr5_+_108083517 0.02 ENST00000281092.4
ENST00000536402.1
FER
fer (fps/fes related) tyrosine kinase
chr9_+_140513438 0.01 ENST00000462484.1
ENST00000334856.6
ENST00000460843.1
EHMT1
euchromatic histone-lysine N-methyltransferase 1
chr1_-_110052302 0.01 ENST00000369864.4
ENST00000369862.1
AMIGO1
adhesion molecule with Ig-like domain 1
chr4_-_125633876 0.01 ENST00000504087.1
ENST00000515641.1
ANKRD50
ankyrin repeat domain 50
chr2_+_115199876 0.01 ENST00000436732.1
ENST00000410059.1
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr1_-_57889687 0.01 ENST00000371236.2
ENST00000371230.1
DAB1
Dab, reelin signal transducer, homolog 1 (Drosophila)
chr8_+_65492756 0.01 ENST00000321870.1
BHLHE22
basic helix-loop-helix family, member e22
chr14_+_55518349 0.00 ENST00000395468.4
MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr1_-_109506036 0.00 ENST00000369976.1
ENST00000356970.2
ENST00000369971.2
ENST00000415331.1
ENST00000357393.4
CLCC1
AKNAD1
chloride channel CLIC-like 1
AKNA domain containing 1
chr20_+_56884752 0.00 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr1_+_42846443 0.00 ENST00000410070.2
ENST00000431473.3
RIMKLA
ribosomal modification protein rimK-like family member A
chr10_+_133918175 0.00 ENST00000298622.4
JAKMIP3
Janus kinase and microtubule interacting protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of AAGGUGC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.2 1.1 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.4 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.1 0.4 GO:1904882 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.4 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.3 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.6 GO:0097338 response to clozapine(GO:0097338)
0.1 0.2 GO:0001922 B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) negative regulation of osteoclast proliferation(GO:0090291)
0.1 0.3 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.2 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059)
0.0 1.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.2 GO:0030047 actin modification(GO:0030047)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.1 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.0 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.2 GO:0097134 Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.9 GO:0042629 mast cell granule(GO:0042629)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.0 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.0 GO:0000811 GINS complex(GO:0000811)
0.0 0.0 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.3 GO:0019961 interferon binding(GO:0019961)
0.1 1.1 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.4 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 1.0 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 1.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 1.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0097001 glycosphingolipid binding(GO:0043208) ceramide binding(GO:0097001)
0.0 0.1 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.0 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.8 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.9 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.5 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits