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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for AAUACUG

Z-value: 0.78

Motif logo

miRNA associated with seed AAUACUG

NamemiRBASE accession
MIMAT0000318
MIMAT0000617
MIMAT0001536

Activity profile of AAUACUG motif

Sorted Z-values of AAUACUG motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_156588350 2.89 ENST00000296518.7
guanylate cyclase 1, soluble, alpha 3
chr13_-_72441315 2.47 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
dachshund homolog 1 (Drosophila)
chr1_+_84543734 1.95 ENST00000370689.2
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_61547894 1.69 ENST00000403491.3
nuclear factor I/A
chr7_-_11871815 1.56 ENST00000423059.4
thrombospondin, type I, domain containing 7A
chr10_-_81205373 1.29 ENST00000372336.3
zinc finger, CCHC domain containing 24
chr9_-_14314066 1.29 ENST00000397575.3
nuclear factor I/B
chr12_+_79258547 1.28 ENST00000457153.2
synaptotagmin I
chr13_-_107187462 1.25 ENST00000245323.4
ephrin-B2
chr10_+_102106829 1.07 ENST00000370355.2
stearoyl-CoA desaturase (delta-9-desaturase)
chr12_-_96794143 1.03 ENST00000543119.2
cyclin-dependent kinase 17
chr8_-_48651648 0.99 ENST00000408965.3
CCAAT/enhancer binding protein (C/EBP), delta
chr7_+_106685079 0.98 ENST00000265717.4
protein kinase, cAMP-dependent, regulatory, type II, beta
chr6_-_16761678 0.97 ENST00000244769.4
ENST00000436367.1
ataxin 1
chr1_+_178694300 0.93 ENST00000367635.3
Ral GEF with PH domain and SH3 binding motif 2
chr5_-_112630598 0.89 ENST00000302475.4
mutated in colorectal cancers
chr7_-_132261253 0.87 ENST00000321063.4
plexin A4
chr5_+_56111361 0.87 ENST00000399503.3
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr3_-_15901278 0.86 ENST00000399451.2
ankyrin repeat domain 28
chr1_+_66999799 0.78 ENST00000371035.3
ENST00000371036.3
ENST00000371037.4
SH3-domain GRB2-like (endophilin) interacting protein 1
chr9_-_80646374 0.78 ENST00000286548.4
guanine nucleotide binding protein (G protein), q polypeptide
chr8_-_89339705 0.76 ENST00000286614.6
matrix metallopeptidase 16 (membrane-inserted)
chr9_+_36036430 0.75 ENST00000377966.3
reversion-inducing-cysteine-rich protein with kazal motifs
chr14_-_105635090 0.73 ENST00000331782.3
ENST00000347004.2
jagged 2
chr10_-_46030841 0.72 ENST00000453424.2
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr13_+_27131887 0.70 ENST00000335327.5
WAS protein family, member 3
chr20_+_10199468 0.70 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chr12_-_31744031 0.69 ENST00000389082.5
DENN/MADD domain containing 5B
chr11_-_66115032 0.69 ENST00000311181.4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr8_-_93115445 0.67 ENST00000523629.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_77656339 0.67 ENST00000538629.1
secretory carrier membrane protein 1
chr2_+_28615669 0.65 ENST00000379619.1
ENST00000264716.4
FOS-like antigen 2
chr5_-_111093406 0.64 ENST00000379671.3
neuronal regeneration related protein
chr12_+_8850471 0.63 ENST00000535829.1
ENST00000357529.3
ribosomal modification protein rimK-like family member B
chr17_+_57408994 0.63 ENST00000312655.4
yippee-like 2 (Drosophila)
chr2_+_198669365 0.61 ENST00000428675.1
phospholipase C-like 1
chr8_-_71316021 0.60 ENST00000452400.2
nuclear receptor coactivator 2
chr12_-_46766577 0.59 ENST00000256689.5
solute carrier family 38, member 2
chr2_-_152684977 0.59 ENST00000428992.2
ENST00000295087.8
ADP-ribosylation factor-like 5A
chr11_+_12695944 0.59 ENST00000361905.4
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr2_+_61108650 0.58 ENST00000295025.8
v-rel avian reticuloendotheliosis viral oncogene homolog
chr12_+_93771659 0.57 ENST00000337179.5
ENST00000415493.2
nudix (nucleoside diphosphate linked moiety X)-type motif 4
chr7_-_35077653 0.57 ENST00000310974.4
dpy-19-like 1 (C. elegans)
chr12_-_15942309 0.56 ENST00000544064.1
ENST00000543523.1
ENST00000536793.1
epidermal growth factor receptor pathway substrate 8
chr4_-_55991752 0.55 ENST00000263923.4
kinase insert domain receptor (a type III receptor tyrosine kinase)
chr14_-_75593708 0.53 ENST00000557673.1
ENST00000238616.5
NIMA-related kinase 9
chr7_-_27183263 0.52 ENST00000222726.3
homeobox A5
chr5_+_138629417 0.52 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
matrin 3
chr1_+_155099927 0.51 ENST00000368407.3
ephrin-A1
chr20_-_4982132 0.51 ENST00000338244.1
ENST00000424750.2
solute carrier family 23 (ascorbic acid transporter), member 2
chr6_-_108395907 0.51 ENST00000193322.3
osteopetrosis associated transmembrane protein 1
chr4_+_87856129 0.49 ENST00000395146.4
ENST00000507468.1
AF4/FMR2 family, member 1
chr6_+_160390102 0.49 ENST00000356956.1
insulin-like growth factor 2 receptor
chr19_+_49617581 0.49 ENST00000391864.3
lin-7 homolog B (C. elegans)
chr2_+_148778570 0.48 ENST00000407073.1
methyl-CpG binding domain protein 5
chr7_-_94285511 0.48 ENST00000265735.7
sarcoglycan, epsilon
chr16_+_8768422 0.47 ENST00000268251.8
ENST00000564714.1
4-aminobutyrate aminotransferase
chrX_+_9983602 0.47 ENST00000380861.4
WWC family member 3
chr9_-_16870704 0.47 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
basonuclin 2
chr6_-_122792919 0.46 ENST00000339697.4
serine incorporator 1
chr5_-_90679145 0.45 ENST00000265138.3
arrestin domain containing 3
chr12_-_109125285 0.44 ENST00000552871.1
ENST00000261401.3
coronin, actin binding protein, 1C
chr17_+_65821780 0.44 ENST00000321892.4
ENST00000335221.5
ENST00000306378.6
bromodomain PHD finger transcription factor
chr14_+_57735614 0.43 ENST00000261558.3
adaptor-related protein complex 5, mu 1 subunit
chr3_+_50192537 0.43 ENST00000002829.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr14_-_35182994 0.43 ENST00000341223.3
cofilin 2 (muscle)
chr2_+_169312350 0.43 ENST00000305747.6
ceramide synthase 6
chr12_+_1800179 0.43 ENST00000357103.4
adiponectin receptor 2
chr1_-_109940550 0.42 ENST00000256637.6
sortilin 1
chrX_-_54522558 0.42 ENST00000375135.3
FYVE, RhoGEF and PH domain containing 1
chr3_-_69435224 0.41 ENST00000398540.3
FERM domain containing 4B
chr19_+_34745442 0.41 ENST00000299505.6
ENST00000588470.1
ENST00000589583.1
ENST00000588338.2
KIAA0355
chr17_-_76870222 0.41 ENST00000585421.1
TIMP metallopeptidase inhibitor 2
chr11_-_46940074 0.40 ENST00000378623.1
ENST00000534404.1
low density lipoprotein receptor-related protein 4
chr17_+_66508537 0.39 ENST00000392711.1
ENST00000585427.1
ENST00000589228.1
ENST00000536854.2
ENST00000588702.1
ENST00000589309.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr15_-_82338460 0.38 ENST00000558133.1
ENST00000329713.4
mex-3 RNA binding family member B
chr11_+_94822968 0.38 ENST00000278505.4
endonuclease domain containing 1
chr6_-_10415470 0.38 ENST00000379604.2
ENST00000379613.3
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr1_+_33005020 0.38 ENST00000373510.4
ENST00000316459.4
zinc finger and BTB domain containing 8A
chr7_+_104654623 0.38 ENST00000311117.3
ENST00000334877.4
ENST00000257745.4
ENST00000334914.7
ENST00000478990.1
ENST00000495267.1
ENST00000476671.1
lysine (K)-specific methyltransferase 2E
chr13_-_103451307 0.37 ENST00000376004.4
KDEL (Lys-Asp-Glu-Leu) containing 1
chr9_-_111882195 0.37 ENST00000374586.3
transmembrane protein 245
chr7_+_94139105 0.37 ENST00000297273.4
CAS1 domain containing 1
chr6_+_135502466 0.36 ENST00000367814.4
v-myb avian myeloblastosis viral oncogene homolog
chr16_+_69221028 0.36 ENST00000336278.4
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr2_+_16080659 0.36 ENST00000281043.3
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr11_+_92085262 0.36 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT atypical cadherin 3
chr3_+_178866199 0.35 ENST00000263967.3
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr1_-_1624083 0.35 ENST00000378662.1
ENST00000234800.6
solute carrier family 35, member E2B
chr14_+_77228532 0.35 ENST00000167106.4
ENST00000554237.1
vasohibin 1
chr1_-_28969517 0.34 ENST00000263974.4
ENST00000373824.4
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr2_+_205410516 0.34 ENST00000406610.2
ENST00000462231.1
par-3 family cell polarity regulator beta
chr14_-_20774092 0.34 ENST00000423949.2
ENST00000553828.1
ENST00000258821.3
tetratricopeptide repeat domain 5
chrX_+_9754461 0.34 ENST00000380913.3
shroom family member 2
chr2_-_160472952 0.33 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
bromodomain adjacent to zinc finger domain, 2B
chr4_-_6383594 0.33 ENST00000335585.5
protein phosphatase 2, regulatory subunit B, gamma
chr10_-_30348439 0.32 ENST00000375377.1
KIAA1462
chr4_-_85887503 0.32 ENST00000509172.1
ENST00000322366.6
ENST00000295888.4
ENST00000502713.1
WD repeat and FYVE domain containing 3
chr9_-_139440314 0.32 ENST00000277541.6
notch 1
chr6_+_17600576 0.32 ENST00000259963.3
family with sequence similarity 8, member A1
chr20_-_23402028 0.32 ENST00000398425.3
ENST00000432543.2
ENST00000377026.4
N-ethylmaleimide-sensitive factor attachment protein, beta
chr11_+_120894781 0.32 ENST00000529397.1
ENST00000528512.1
ENST00000422003.2
tubulin folding cofactor E-like
chr7_-_6312206 0.31 ENST00000350796.3
cytohesin 3
chr11_+_128563652 0.31 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr1_-_225615599 0.30 ENST00000421383.1
ENST00000272163.4
lamin B receptor
chr5_+_138678131 0.30 ENST00000394795.2
ENST00000510080.1
poly(A) binding protein interacting protein 2
chr19_+_34287751 0.30 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
potassium channel tetramerization domain containing 15
chr3_+_150126101 0.30 ENST00000361875.3
ENST00000361136.2
TSC22 domain family, member 2
chr18_-_53255766 0.29 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
transcription factor 4
chr22_+_40297079 0.29 ENST00000344138.4
ENST00000543252.1
GRB2-related adaptor protein 2
chr6_+_119215308 0.29 ENST00000229595.5
anti-silencing function 1A histone chaperone
chr3_-_27498235 0.28 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr14_-_70883708 0.28 ENST00000256366.4
synaptojanin 2 binding protein
chr2_-_240322643 0.28 ENST00000345617.3
histone deacetylase 4
chr8_+_70378852 0.28 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
sulfatase 1
chr13_-_29069232 0.28 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
fms-related tyrosine kinase 1
chr2_-_39664405 0.28 ENST00000341681.5
ENST00000263881.3
mitogen-activated protein kinase kinase kinase kinase 3
chr15_+_72766651 0.28 ENST00000379887.4
ariadne RBR E3 ubiquitin protein ligase 1
chr21_+_17102311 0.28 ENST00000285679.6
ENST00000351097.5
ENST00000285681.2
ENST00000400183.2
ubiquitin specific peptidase 25
chr1_-_231560790 0.27 ENST00000366641.3
egl-9 family hypoxia-inducible factor 1
chr5_-_14871866 0.27 ENST00000284268.6
ANKH inorganic pyrophosphate transport regulator
chr4_+_113066552 0.27 ENST00000309733.5
chromosome 4 open reading frame 32
chr4_+_141294628 0.26 ENST00000512749.1
ENST00000608372.1
ENST00000506597.1
ENST00000394201.4
ENST00000510586.1
short coiled-coil protein
chr1_+_24882560 0.26 ENST00000374392.2
noncompact myelin associated protein
chr10_+_105726862 0.26 ENST00000335753.4
ENST00000369755.3
STE20-like kinase
chr1_+_87380299 0.26 ENST00000370551.4
ENST00000370550.5
heparan sulfate 2-O-sulfotransferase 1
chr8_+_107670064 0.26 ENST00000312046.6
oxidation resistance 1
chr16_-_4166186 0.26 ENST00000294016.3
adenylate cyclase 9
chr10_+_31608054 0.25 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
zinc finger E-box binding homeobox 1
chr2_-_62733476 0.25 ENST00000335390.5
transmembrane protein 17
chr5_-_107717058 0.25 ENST00000359660.5
F-box and leucine-rich repeat protein 17
chr17_-_62207485 0.25 ENST00000433197.3
endoplasmic reticulum to nucleus signaling 1
chrX_+_41192595 0.25 ENST00000399959.2
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr17_-_19771216 0.25 ENST00000395544.4
unc-51 like autophagy activating kinase 2
chr8_+_95835438 0.25 ENST00000521860.1
ENST00000519457.1
ENST00000519053.1
ENST00000523731.1
ENST00000447247.1
integrator complex subunit 8
chr11_+_33278811 0.24 ENST00000303296.4
ENST00000379016.3
homeodomain interacting protein kinase 3
chr17_+_5185552 0.24 ENST00000262477.6
ENST00000408982.2
ENST00000575991.1
ENST00000537505.1
ENST00000546142.2
rabaptin, RAB GTPase binding effector protein 1
chr17_-_45266542 0.24 ENST00000531206.1
ENST00000527547.1
ENST00000446365.2
ENST00000575483.1
ENST00000066544.3
cell division cycle 27
chr3_-_124774802 0.24 ENST00000311127.4
heart development protein with EGF-like domains 1
chr1_+_64936428 0.24 ENST00000371073.2
ENST00000290039.5
cache domain containing 1
chr9_+_5629025 0.24 ENST00000251879.6
ENST00000414202.2
KIAA1432
chr14_+_71374122 0.23 ENST00000304743.2
ENST00000238570.5
pecanex homolog (Drosophila)
chr2_+_204192942 0.23 ENST00000295851.5
ENST00000261017.5
abl-interactor 2
chr18_+_19321281 0.23 ENST00000261537.6
mindbomb E3 ubiquitin protein ligase 1
chr6_-_13711773 0.23 ENST00000011619.3
RAN binding protein 9
chr4_+_38665810 0.23 ENST00000261438.5
ENST00000514033.1
Kruppel-like factor 3 (basic)
chr9_-_15510989 0.23 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PC4 and SFRS1 interacting protein 1
chr13_-_107220455 0.23 ENST00000400198.3
arginine and glutamate rich 1
chr22_+_29168652 0.22 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
coiled-coil domain containing 117
chrX_-_20284958 0.22 ENST00000379565.3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr14_-_34931458 0.22 ENST00000298130.4
serine palmitoyltransferase, small subunit A
chr4_+_144257915 0.22 ENST00000262995.4
GRB2-associated binding protein 1
chr17_-_76713100 0.22 ENST00000585509.1
cytohesin 1
chr6_-_97285336 0.22 ENST00000229955.3
ENST00000417980.1
G protein-coupled receptor 63
chr10_+_22610124 0.22 ENST00000376663.3
BMI1 polycomb ring finger oncogene
chr17_+_73629500 0.21 ENST00000375215.3
small integral membrane protein 5
chr1_-_120190396 0.21 ENST00000421812.2
zinc finger protein 697
chr2_+_32288725 0.21 ENST00000315285.3
spastin
chr3_+_141106643 0.21 ENST00000514251.1
zinc finger and BTB domain containing 38
chr5_-_132299313 0.20 ENST00000265343.5
AF4/FMR2 family, member 4
chr2_+_231577532 0.20 ENST00000258418.5
calcium binding protein 39
chr12_+_56325812 0.20 ENST00000394147.1
ENST00000551156.1
ENST00000553783.1
ENST00000557080.1
ENST00000432422.3
ENST00000556001.1
diacylglycerol kinase, alpha 80kDa
chr14_+_36295504 0.20 ENST00000216807.7
breast cancer metastasis-suppressor 1-like
chr18_+_67956135 0.20 ENST00000397942.3
suppressor of cytokine signaling 6
chr16_-_15736953 0.19 ENST00000548025.1
ENST00000551742.1
ENST00000602337.1
ENST00000344181.3
ENST00000396368.3
KIAA0430
chr6_-_110500905 0.19 ENST00000392587.2
WAS protein family, member 1
chr3_+_14989076 0.19 ENST00000413118.1
ENST00000425241.1
nuclear receptor subfamily 2, group C, member 2
chr14_+_53196872 0.19 ENST00000442123.2
ENST00000354586.4
serine/threonine/tyrosine interacting protein
chrX_+_73641286 0.19 ENST00000587091.1
solute carrier family 16, member 2 (thyroid hormone transporter)
chr3_-_33138286 0.19 ENST00000416695.2
ENST00000342462.4
ENST00000399402.3
transmembrane protein with metallophosphoesterase domain
galactosidase, beta 1
chr16_+_85646763 0.19 ENST00000411612.1
ENST00000253458.7
Gse1 coiled-coil protein
chr6_+_52535878 0.19 ENST00000211314.4
transmembrane protein 14A
chr20_-_48729670 0.19 ENST00000371657.5
ubiquitin-conjugating enzyme E2 variant 1
chr8_+_42128812 0.19 ENST00000520810.1
ENST00000416505.2
ENST00000519735.1
ENST00000520835.1
ENST00000379708.3
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr15_-_49338748 0.19 ENST00000559471.1
SECIS binding protein 2-like
chr9_-_74980113 0.19 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
zinc finger, AN1-type domain 5
chr8_+_74206829 0.18 ENST00000240285.5
retinol dehydrogenase 10 (all-trans)
chr11_+_74459876 0.18 ENST00000299563.4
ring finger protein 169
chr21_+_35445827 0.18 ENST00000608209.1
ENST00000381151.3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr1_+_229406847 0.18 ENST00000366690.4
RAB4A, member RAS oncogene family
chr10_+_97803151 0.18 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
cyclin J
chr8_-_22550815 0.18 ENST00000317216.2
early growth response 3
chr16_+_68344981 0.17 ENST00000441236.1
ENST00000348497.4
ENST00000339507.5
protein arginine methyltransferase 7
chr15_+_52121822 0.17 ENST00000558455.1
ENST00000308580.7
tropomodulin 3 (ubiquitous)
chr16_-_23160591 0.17 ENST00000219689.7
ubiquitin specific peptidase 31
chr3_+_182511266 0.17 ENST00000323116.5
ENST00000493826.1
ATPase, class VI, type 11B
chr3_-_71774516 0.17 ENST00000425534.3
eukaryotic translation initiation factor 4E family member 3
chr15_+_44580899 0.17 ENST00000559222.1
ENST00000299957.6
cancer susceptibility candidate 4
chr3_+_158991025 0.17 ENST00000337808.6
IQCJ-SCHIP1 readthrough
chr13_-_30881621 0.17 ENST00000380615.3
katanin p60 subunit A-like 1
chr9_-_36400213 0.17 ENST00000259605.6
ENST00000353739.4
ring finger protein 38
chr1_-_205601064 0.17 ENST00000357992.4
ENST00000289703.4
ELK4, ETS-domain protein (SRF accessory protein 1)
chr2_-_216300784 0.16 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
fibronectin 1
chr8_+_29952914 0.16 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
leptin receptor overlapping transcript-like 1
chr1_+_200708671 0.16 ENST00000358823.2
calmodulin regulated spectrin-associated protein family, member 2
chr12_-_122907091 0.16 ENST00000358808.2
ENST00000361654.4
ENST00000539080.1
ENST00000537178.1
CAP-GLY domain containing linker protein 1
chr9_+_131644388 0.16 ENST00000372600.4
leucine rich repeat containing 8 family, member A
chr12_+_53774423 0.16 ENST00000426431.2
Sp1 transcription factor
chr2_-_54197915 0.16 ENST00000404125.1
proteasome (prosome, macropain) activator subunit 4
chr11_-_94964354 0.16 ENST00000536441.1
sestrin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of AAUACUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.4 1.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.4 2.9 GO:0097338 response to clozapine(GO:0097338)
0.4 1.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.3 2.5 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.3 0.9 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.2 0.7 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.2 0.9 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.2 1.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 0.5 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 0.5 GO:0060435 bronchiole development(GO:0060435)
0.2 0.8 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.1 0.4 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.4 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 1.0 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.4 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.5 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.8 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.3 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.6 GO:1901906 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:0014028 notochord formation(GO:0014028)
0.1 0.4 GO:0003409 optic cup structural organization(GO:0003409)
0.1 1.6 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.5 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.5 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.1 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.3 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 0.8 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.1 0.4 GO:1905049 regulation of Rap protein signal transduction(GO:0032487) negative regulation of metallopeptidase activity(GO:1905049)
0.1 0.3 GO:1903347 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.5 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.6 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.6 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.8 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.2 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.1 GO:2000977 regulation of forebrain neuron differentiation(GO:2000977)
0.1 0.5 GO:0097490 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1 0.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.2 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.1 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.4 GO:0032328 alanine transport(GO:0032328)
0.0 0.3 GO:0030805 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.4 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.3 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:1904978 regulation of endosome organization(GO:1904978)
0.0 0.1 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 1.5 GO:0060074 synapse maturation(GO:0060074)
0.0 0.3 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.3 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.6 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.3 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0035549 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.2 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.8 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0048752 negative regulation of endothelial cell differentiation(GO:0045602) semicircular canal morphogenesis(GO:0048752)
0.0 0.3 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.1 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.5 GO:0007379 segment specification(GO:0007379)
0.0 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.2 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.2 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.2 GO:0051136 regulation of NK T cell differentiation(GO:0051136)
0.0 0.0 GO:0060872 semicircular canal development(GO:0060872)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.3 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.0 GO:0051586 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.5 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.3 GO:0043476 pigment accumulation(GO:0043476) cellular pigment accumulation(GO:0043482)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.9 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.3 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.0 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.0 GO:0043400 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462) intestinal epithelial cell migration(GO:0061582)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.0 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.0 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.0 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.0 GO:0071314 cellular response to cocaine(GO:0071314)
0.0 1.1 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 3.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.5 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 0.6 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 2.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.5 GO:0097443 sorting endosome(GO:0097443)
0.1 0.3 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.1 1.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.9 GO:0016600 flotillin complex(GO:0016600)
0.1 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.7 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.2 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.2 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.8 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.3 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 1.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.0 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.4 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.2 1.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 0.5 GO:0008523 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.6 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.8 GO:0034046 poly(G) binding(GO:0034046)
0.1 2.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.8 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.5 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 1.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.3 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.6 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 2.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.3 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.3 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.4 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 1.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0033677 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.0 0.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.0 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 1.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.8 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.5 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.2 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 1.2 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.3 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.5 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 1.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 2.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.2 PID TCPTP PATHWAY Signaling events mediated by TCPTP

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 3.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 0.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 0.1 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 2.8 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.9 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.7 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.1 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation