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Inflammatory response time course, HUVEC (Wada et al., 2009)
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Results for AAUCUCA
Z-value: 0.15
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miRNA associated with seed AAUCUCA
| Name | miRBASE accession |
|---|---|
|
hsa-miR-216a-5p
|
MIMAT0000273 |
Activity profile of AAUCUCA motif
Sorted Z-values of AAUCUCA motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr18_-_22932080 | 0.47 |
ENST00000584787.1
ENST00000361524.3 ENST00000538137.2 |
ZNF521
|
zinc finger protein 521 |
| chr11_+_74459876 | 0.22 |
ENST00000299563.4
|
RNF169
|
ring finger protein 169 |
| chr7_+_12250886 | 0.22 |
ENST00000444443.1
ENST00000396667.3 |
TMEM106B
|
transmembrane protein 106B |
| chr9_-_20622478 | 0.19 |
ENST00000355930.6
ENST00000380338.4 |
MLLT3
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
| chr18_+_59992527 | 0.17 |
ENST00000586569.1
|
TNFRSF11A
|
tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| chr6_-_44265411 | 0.12 |
ENST00000371505.4
|
TCTE1
|
t-complex-associated-testis-expressed 1 |
| chr6_+_42749759 | 0.11 |
ENST00000314073.5
|
GLTSCR1L
|
GLTSCR1-like |
| chrX_-_20284958 | 0.10 |
ENST00000379565.3
|
RPS6KA3
|
ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
| chr17_-_73975444 | 0.09 |
ENST00000293217.5
ENST00000537812.1 |
ACOX1
|
acyl-CoA oxidase 1, palmitoyl |
| chr13_-_31038370 | 0.07 |
ENST00000399489.1
ENST00000339872.4 |
HMGB1
|
high mobility group box 1 |
| chr4_+_99916765 | 0.06 |
ENST00000296411.6
|
METAP1
|
methionyl aminopeptidase 1 |
| chr5_+_122424816 | 0.05 |
ENST00000407847.4
|
PRDM6
|
PR domain containing 6 |
| chr1_-_53793584 | 0.05 |
ENST00000354412.3
ENST00000347547.2 ENST00000306052.6 |
LRP8
|
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor |
| chr18_+_59854480 | 0.04 |
ENST00000256858.6
ENST00000398130.2 |
KIAA1468
|
KIAA1468 |
| chr1_-_67896095 | 0.02 |
ENST00000370994.4
|
SERBP1
|
SERPINE1 mRNA binding protein 1 |
| chr17_+_30677136 | 0.02 |
ENST00000394670.4
ENST00000321233.6 ENST00000394673.2 ENST00000341711.6 ENST00000579634.1 ENST00000580759.1 ENST00000342555.6 ENST00000577908.1 ENST00000394679.5 ENST00000582165.1 |
ZNF207
|
zinc finger protein 207 |
| chr14_-_80677970 | 0.02 |
ENST00000438257.4
|
DIO2
|
deiodinase, iodothyronine, type II |
| chr13_-_45915221 | 0.01 |
ENST00000309246.5
ENST00000379060.4 ENST00000379055.1 ENST00000527226.1 ENST00000379056.1 |
TPT1
|
tumor protein, translationally-controlled 1 |
| chr5_+_149109825 | 0.01 |
ENST00000360453.4
ENST00000394320.3 ENST00000309241.5 |
PPARGC1B
|
peroxisome proliferator-activated receptor gamma, coactivator 1 beta |
| chr5_-_178054105 | 0.01 |
ENST00000316308.4
|
CLK4
|
CDC-like kinase 4 |
| chr17_+_53342311 | 0.01 |
ENST00000226067.5
|
HLF
|
hepatic leukemia factor |
| chr7_+_35840542 | 0.01 |
ENST00000435235.1
ENST00000399034.2 ENST00000350320.6 ENST00000469679.2 |
SEPT7
|
septin 7 |
| chr10_+_11206925 | 0.00 |
ENST00000354440.2
ENST00000315874.4 ENST00000427450.1 |
CELF2
|
CUGBP, Elav-like family member 2 |
| chr15_+_40733387 | 0.00 |
ENST00000416165.1
|
BAHD1
|
bromo adjacent homology domain containing 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of AAUCUCA
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0071810 | circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009) |
| 0.0 | 0.1 | GO:0002840 | plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) |
| 0.0 | 0.2 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.0 | GO:0038025 | reelin receptor activity(GO:0038025) |
| 0.0 | 0.1 | GO:0003997 | acyl-CoA oxidase activity(GO:0003997) |
| 0.0 | 0.1 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |