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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for AAUCUCU

Z-value: 0.21

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miRNA associated with seed AAUCUCU

NamemiRBASE accession
hsa-miR-216b-5p
MIMAT0004959

Activity profile of AAUCUCU motif

Sorted Z-values of AAUCUCU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_107683644 0.16 ENST00000370067.1
NTNG1
netrin G1
chr11_+_12308447 0.15 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr6_+_42749759 0.13 ENST00000314073.5
GLTSCR1L
GLTSCR1-like
chr18_+_59854480 0.13 ENST00000256858.6
ENST00000398130.2
KIAA1468
KIAA1468
chr14_+_71108460 0.13 ENST00000256367.2
TTC9
tetratricopeptide repeat domain 9
chr4_+_99916765 0.11 ENST00000296411.6
METAP1
methionyl aminopeptidase 1
chr7_+_12250886 0.10 ENST00000444443.1
ENST00000396667.3
TMEM106B
transmembrane protein 106B
chr7_+_21467642 0.10 ENST00000222584.3
ENST00000432066.2
SP4
Sp4 transcription factor
chr17_+_64298944 0.09 ENST00000413366.3
PRKCA
protein kinase C, alpha
chrX_+_122993827 0.08 ENST00000371199.3
XIAP
X-linked inhibitor of apoptosis
chr8_+_76452097 0.06 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr10_+_11206925 0.06 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2
CUGBP, Elav-like family member 2
chr11_+_60739140 0.06 ENST00000313421.7
CD6
CD6 molecule
chr12_+_60083118 0.06 ENST00000261187.4
ENST00000543448.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr4_-_105416039 0.05 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr1_+_63788730 0.05 ENST00000371116.2
FOXD3
forkhead box D3
chr10_-_104474128 0.05 ENST00000260746.5
ARL3
ADP-ribosylation factor-like 3
chr17_+_30677136 0.05 ENST00000394670.4
ENST00000321233.6
ENST00000394673.2
ENST00000341711.6
ENST00000579634.1
ENST00000580759.1
ENST00000342555.6
ENST00000577908.1
ENST00000394679.5
ENST00000582165.1
ZNF207
zinc finger protein 207
chr5_+_173315283 0.04 ENST00000265085.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr9_-_20622478 0.04 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr5_+_149109825 0.04 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr6_+_114178512 0.04 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr14_+_57735614 0.03 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr7_+_35840542 0.03 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
SEPT7
septin 7
chr13_-_31038370 0.03 ENST00000399489.1
ENST00000339872.4
HMGB1
high mobility group box 1
chr1_-_153895377 0.03 ENST00000368655.4
GATAD2B
GATA zinc finger domain containing 2B
chr8_+_48920960 0.02 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
UBE2V2
ubiquitin-conjugating enzyme E2 variant 2
chr16_+_67678818 0.02 ENST00000334583.6
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr2_-_242212227 0.02 ENST00000427007.1
ENST00000458564.1
ENST00000452065.1
ENST00000427183.2
ENST00000426343.1
ENST00000422080.1
ENST00000449504.1
ENST00000449864.1
ENST00000391975.1
HDLBP
high density lipoprotein binding protein
chr3_-_113465065 0.02 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr10_-_120101804 0.02 ENST00000369183.4
ENST00000369172.4
FAM204A
family with sequence similarity 204, member A
chr15_+_73344791 0.01 ENST00000261908.6
NEO1
neogenin 1
chr12_+_111471828 0.01 ENST00000261726.6
CUX2
cut-like homeobox 2
chr18_-_22932080 0.00 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
ZNF521
zinc finger protein 521

Network of associatons between targets according to the STRING database.

First level regulatory network of AAUCUCU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:2000705 histone H3-T6 phosphorylation(GO:0035408) dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.1 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0042585 germinal vesicle(GO:0042585)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine