Project

Inflammatory response time course, HUVEC (Wada et al., 2009)

Navigation
Downloads

Results for ACUGGCC

Z-value: 0.29

Motif logo

logo of

miRNA associated with seed ACUGGCC

NamemiRBASE accession
hsa-miR-193a-3p
MIMAT0000459
hsa-miR-193b-3p
MIMAT0002819

Activity profile of ACUGGCC motif

Sorted Z-values of ACUGGCC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_68165657 0.94 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr4_+_55524085 0.91 ENST00000412167.2
ENST00000288135.5
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr2_+_12857015 0.71 ENST00000155926.4
TRIB2
tribbles pseudokinase 2
chr1_-_92351769 0.62 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr8_-_93115445 0.46 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_+_79258547 0.43 ENST00000457153.2
SYT1
synaptotagmin I
chr6_-_16761678 0.37 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr3_-_124774802 0.33 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr6_+_86159821 0.31 ENST00000369651.3
NT5E
5'-nucleotidase, ecto (CD73)
chr22_-_39548627 0.27 ENST00000216133.5
CBX7
chromobox homolog 7
chr18_-_53255766 0.25 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr1_+_76540386 0.22 ENST00000328299.3
ST6GALNAC3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr5_+_177540444 0.22 ENST00000274605.5
N4BP3
NEDD4 binding protein 3
chr20_-_4982132 0.21 ENST00000338244.1
ENST00000424750.2
SLC23A2
solute carrier family 23 (ascorbic acid transporter), member 2
chr8_-_89339705 0.18 ENST00000286614.6
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr10_+_97515409 0.17 ENST00000371207.3
ENST00000543964.1
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr2_+_204192942 0.16 ENST00000295851.5
ENST00000261017.5
ABI2
abl-interactor 2
chr16_-_4166186 0.15 ENST00000294016.3
ADCY9
adenylate cyclase 9
chr4_+_126237554 0.15 ENST00000394329.3
FAT4
FAT atypical cadherin 4
chrX_-_24045303 0.14 ENST00000328046.8
KLHL15
kelch-like family member 15
chr17_+_61086917 0.13 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr12_-_31744031 0.12 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chr16_+_85646763 0.12 ENST00000411612.1
ENST00000253458.7
GSE1
Gse1 coiled-coil protein
chr7_+_104654623 0.12 ENST00000311117.3
ENST00000334877.4
ENST00000257745.4
ENST00000334914.7
ENST00000478990.1
ENST00000495267.1
ENST00000476671.1
KMT2E
lysine (K)-specific methyltransferase 2E
chr18_+_46065393 0.12 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr17_-_38020392 0.11 ENST00000346872.3
ENST00000439167.2
ENST00000377945.3
ENST00000394189.2
ENST00000377944.3
ENST00000377958.2
ENST00000535189.1
ENST00000377952.2
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr11_+_33563821 0.11 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr5_+_38846101 0.10 ENST00000274276.3
OSMR
oncostatin M receptor
chr10_-_94333784 0.09 ENST00000265986.6
IDE
insulin-degrading enzyme
chr14_+_90863327 0.09 ENST00000356978.4
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr6_-_75994536 0.09 ENST00000475111.2
ENST00000230461.6
TMEM30A
transmembrane protein 30A
chr1_+_183605200 0.09 ENST00000304685.4
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr12_-_96794143 0.08 ENST00000543119.2
CDK17
cyclin-dependent kinase 17
chr11_-_46940074 0.08 ENST00000378623.1
ENST00000534404.1
LRP4
low density lipoprotein receptor-related protein 4
chr1_+_145507587 0.08 ENST00000330165.8
ENST00000369307.3
RBM8A
RNA binding motif protein 8A
chr22_+_24951436 0.08 ENST00000215829.3
SNRPD3
small nuclear ribonucleoprotein D3 polypeptide 18kDa
chr7_+_108210012 0.08 ENST00000249356.3
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr5_+_78532003 0.07 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr6_-_47277634 0.07 ENST00000296861.2
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr6_-_2634820 0.07 ENST00000296847.3
C6orf195
chromosome 6 open reading frame 195
chr11_+_128563652 0.07 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr11_+_120207787 0.07 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr19_-_14629224 0.07 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr10_-_102279586 0.06 ENST00000370345.3
ENST00000451524.1
ENST00000370329.5
SEC31B
SEC31 homolog B (S. cerevisiae)
chr11_-_27494279 0.06 ENST00000379214.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr17_+_61699766 0.06 ENST00000579585.1
ENST00000584573.1
ENST00000361733.3
ENST00000361357.3
MAP3K3
mitogen-activated protein kinase kinase kinase 3
chr14_+_57046500 0.05 ENST00000261556.6
TMEM260
transmembrane protein 260
chr17_+_55333876 0.05 ENST00000284073.2
MSI2
musashi RNA-binding protein 2
chr5_+_172483347 0.05 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF
CREB3 regulatory factor
chr15_-_61521495 0.05 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr2_-_38978492 0.05 ENST00000409276.1
ENST00000446327.2
ENST00000313117.6
SRSF7
serine/arginine-rich splicing factor 7
chr1_-_150552006 0.05 ENST00000307940.3
ENST00000369026.2
MCL1
myeloid cell leukemia sequence 1 (BCL2-related)
chr1_+_203764742 0.04 ENST00000432282.1
ENST00000453771.1
ENST00000367214.1
ENST00000367212.3
ENST00000332127.4
ZC3H11A
zinc finger CCCH-type containing 11A
chr9_+_131644388 0.04 ENST00000372600.4
LRRC8A
leucine rich repeat containing 8 family, member A
chr9_-_37465396 0.04 ENST00000307750.4
ZBTB5
zinc finger and BTB domain containing 5
chr13_+_111365602 0.04 ENST00000333219.7
ING1
inhibitor of growth family, member 1
chr12_+_110437328 0.04 ENST00000261739.4
ANKRD13A
ankyrin repeat domain 13A
chr11_-_17035943 0.04 ENST00000355661.3
ENST00000532079.1
ENST00000448080.2
ENST00000531066.1
PLEKHA7
pleckstrin homology domain containing, family A member 7
chr13_+_98794810 0.03 ENST00000595437.1
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr12_+_56137064 0.03 ENST00000257868.5
ENST00000546799.1
GDF11
growth differentiation factor 11
chr5_+_65222299 0.03 ENST00000284037.5
ERBB2IP
erbb2 interacting protein
chr14_-_50698276 0.03 ENST00000216373.5
SOS2
son of sevenless homolog 2 (Drosophila)
chr20_+_57226284 0.03 ENST00000458280.1
ENST00000355957.5
ENST00000361770.5
ENST00000312283.8
ENST00000412911.1
ENST00000359617.4
ENST00000371141.4
STX16
syntaxin 16
chr1_-_166028709 0.03 ENST00000595430.1
AL626787.1
AL626787.1
chr22_+_24666763 0.03 ENST00000437398.1
ENST00000421374.1
ENST00000314328.9
ENST00000541492.1
SPECC1L
sperm antigen with calponin homology and coiled-coil domains 1-like
chr22_+_40390930 0.03 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr7_-_143059845 0.02 ENST00000443739.2
FAM131B
family with sequence similarity 131, member B
chr20_+_42086525 0.02 ENST00000244020.3
SRSF6
serine/arginine-rich splicing factor 6
chr6_-_166075557 0.02 ENST00000539869.2
ENST00000366882.1
PDE10A
phosphodiesterase 10A
chr6_+_39760783 0.02 ENST00000398904.2
ENST00000538976.1
DAAM2
dishevelled associated activator of morphogenesis 2
chr14_-_23451845 0.02 ENST00000262713.2
AJUBA
ajuba LIM protein
chr14_-_80677970 0.02 ENST00000438257.4
DIO2
deiodinase, iodothyronine, type II
chr18_-_47013586 0.02 ENST00000318240.3
ENST00000579820.1
C18orf32
chromosome 18 open reading frame 32
chr2_+_113931513 0.02 ENST00000245796.6
ENST00000441564.3
PSD4
pleckstrin and Sec7 domain containing 4
chr11_-_71823796 0.02 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
ANAPC15
anaphase promoting complex subunit 15
chr12_+_11802753 0.02 ENST00000396373.4
ETV6
ets variant 6
chr1_+_109792641 0.02 ENST00000271332.3
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2
chr4_+_41992489 0.02 ENST00000264451.7
SLC30A9
solute carrier family 30 (zinc transporter), member 9
chr12_-_50297638 0.02 ENST00000320634.3
FAIM2
Fas apoptotic inhibitory molecule 2
chr1_-_26232951 0.02 ENST00000426559.2
ENST00000455785.2
STMN1
stathmin 1
chr14_+_102228123 0.01 ENST00000422945.2
ENST00000554442.1
ENST00000556260.2
ENST00000328724.5
ENST00000557268.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr17_+_61627814 0.01 ENST00000310827.4
ENST00000431926.1
ENST00000415273.2
DCAF7
DDB1 and CUL4 associated factor 7
chr5_-_133512683 0.01 ENST00000353411.6
SKP1
S-phase kinase-associated protein 1
chr4_-_87281224 0.01 ENST00000395169.3
ENST00000395161.2
MAPK10
mitogen-activated protein kinase 10
chr2_-_69870835 0.01 ENST00000409085.4
ENST00000406297.3
AAK1
AP2 associated kinase 1
chr2_+_242641442 0.01 ENST00000313552.6
ENST00000406941.1
ING5
inhibitor of growth family, member 5
chr1_-_169863016 0.01 ENST00000367772.4
ENST00000367771.6
SCYL3
SCY1-like 3 (S. cerevisiae)
chr17_+_48796905 0.01 ENST00000505658.1
ENST00000393227.2
ENST00000240304.1
ENST00000311571.3
ENST00000505619.1
ENST00000544170.1
ENST00000510984.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr2_-_206950781 0.01 ENST00000403263.1
INO80D
INO80 complex subunit D
chr2_+_29204161 0.01 ENST00000379558.4
ENST00000403861.2
FAM179A
family with sequence similarity 179, member A
chr2_-_217560248 0.01 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr14_-_77495007 0.01 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr11_-_115375107 0.01 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr5_+_179921430 0.01 ENST00000393356.1
CNOT6
CCR4-NOT transcription complex, subunit 6
chr11_-_128392085 0.00 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr12_+_56623827 0.00 ENST00000424625.1
ENST00000419753.1
ENST00000454355.2
ENST00000417965.1
ENST00000436633.1
SLC39A5
solute carrier family 39 (zinc transporter), member 5
chr15_+_64443905 0.00 ENST00000325881.4
SNX22
sorting nexin 22
chr17_-_66287257 0.00 ENST00000327268.4
SLC16A6
solute carrier family 16, member 6
chr1_-_1243392 0.00 ENST00000354700.5
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr10_-_38146510 0.00 ENST00000395867.3
ZNF248
zinc finger protein 248
chr1_+_26126667 0.00 ENST00000361547.2
ENST00000354177.4
ENST00000374315.1
SEPN1
selenoprotein N, 1
chr11_+_66188475 0.00 ENST00000311034.2
NPAS4
neuronal PAS domain protein 4
chr8_-_91095099 0.00 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr17_+_44668035 0.00 ENST00000398238.4
ENST00000225282.8
NSF
N-ethylmaleimide-sensitive factor

Network of associatons between targets according to the STRING database.

First level regulatory network of ACUGGCC

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.2 0.9 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 0.6 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.4 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.7 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.3 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.1 0.2 GO:0070904 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.1 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.0 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.4 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.9 GO:0042629 mast cell granule(GO:0042629)
0.0 0.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.2 GO:0008523 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.8 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.7 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway