Project
Inflammatory response time course, HUVEC (Wada et al., 2009)
Navigation
Downloads
Results for AGCACCA
Z-value: 0.69
Motif logo
miRNA associated with seed AGCACCA
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_94023873 Show fit | 1.87 |
ENST00000297268.6
|
collagen, type I, alpha 2 |
|
| chr5_-_43313574 Show fit | 1.17 |
ENST00000325110.6
ENST00000433297.2 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
|
| chr5_+_74632993 Show fit | 0.89 |
ENST00000287936.4
|
3-hydroxy-3-methylglutaryl-CoA reductase |
|
| chr5_-_141704566 Show fit | 0.65 |
ENST00000344120.4
ENST00000434127.2 |
sprouty homolog 4 (Drosophila) |
|
| chr5_-_78281603 Show fit | 0.60 |
ENST00000264914.4
|
arylsulfatase B |
|
| chr4_+_144257915 Show fit | 0.60 |
ENST00000262995.4
|
GRB2-associated binding protein 1 |
|
| chr1_+_185703513 Show fit | 0.57 |
ENST00000271588.4
ENST00000367492.2 |
hemicentin 1 |
|
| chr16_+_57406368 Show fit | 0.56 |
ENST00000006053.6
ENST00000563383.1 |
chemokine (C-X3-C motif) ligand 1 |
|
| chr3_+_72937182 Show fit | 0.55 |
ENST00000389617.4
|
glucoside xylosyltransferase 2 |
|
| chr17_+_57408994 Show fit | 0.54 |
ENST00000312655.4
|
yippee-like 2 (Drosophila) |
Network of associatons between targets according to the STRING database.
First level regulatory network of AGCACCA
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.7 | GO:0043589 | skin morphogenesis(GO:0043589) |
| 0.1 | 1.3 | GO:0071397 | cellular response to cholesterol(GO:0071397) |
| 0.1 | 0.9 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.2 | 0.6 | GO:0061582 | intestinal epithelial cell migration(GO:0061582) |
| 0.2 | 0.6 | GO:0050902 | leukocyte adhesive activation(GO:0050902) |
| 0.0 | 0.6 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.2 | 0.5 | GO:0060940 | epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) |
| 0.2 | 0.5 | GO:0003275 | apoptotic process involved in outflow tract morphogenesis(GO:0003275) negative regulation of alkaline phosphatase activity(GO:0010693) uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) |
| 0.2 | 0.5 | GO:0071812 | circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009) |
| 0.2 | 0.5 | GO:0021827 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.4 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.0 | 1.5 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 0.8 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 0.7 | GO:0098645 | network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) |
| 0.0 | 0.6 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.0 | 0.6 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 0.5 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 0.5 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 0.4 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.1 | 0.3 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.4 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.2 | 1.2 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.0 | 0.9 | GO:0070402 | NADPH binding(GO:0070402) |
| 0.1 | 0.7 | GO:0035252 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.0 | 0.7 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.0 | 0.7 | GO:0016303 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) |
| 0.2 | 0.6 | GO:0003943 | N-acetylgalactosamine-4-sulfatase activity(GO:0003943) |
| 0.0 | 0.6 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.0 | 0.6 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.1 | 0.5 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.9 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.2 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.2 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.0 | 0.8 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.7 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 0.6 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.5 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 0.5 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.0 | 0.4 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.2 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.1 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 1.6 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.0 | 1.2 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.8 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.0 | 0.7 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 0.6 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.0 | 0.6 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.0 | 0.6 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 0.6 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.0 | 0.5 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |