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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for AGCAGCA

Z-value: 0.92

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miRNA associated with seed AGCAGCA

NamemiRBASE accession
hsa-miR-15a-5p
MIMAT0000068
hsa-miR-15b-5p
MIMAT0000417
hsa-miR-16-5p
MIMAT0000069
hsa-miR-195-5p
MIMAT0000461
hsa-miR-424-5p
MIMAT0001341
hsa-miR-497-5p
MIMAT0002820
hsa-miR-6838-5p
MIMAT0027578

Activity profile of AGCAGCA motif

Sorted Z-values of AGCAGCA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_76944621 4.95 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr16_+_57406368 3.08 ENST00000006053.6
ENST00000563383.1
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr8_+_23386305 2.96 ENST00000519973.1
SLC25A37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr19_+_4229495 2.92 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr8_+_23430157 2.88 ENST00000399967.3
FP15737
FP15737
chr1_+_65613217 2.66 ENST00000545314.1
AK4
adenylate kinase 4
chr8_+_17354587 2.63 ENST00000494857.1
ENST00000522656.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr5_+_127419449 2.55 ENST00000262461.2
ENST00000343225.4
SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
chr6_-_134639180 2.50 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr3_-_123603137 2.40 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
MYLK
myosin light chain kinase
chr1_-_120612240 2.36 ENST00000256646.2
NOTCH2
notch 2
chr15_+_67358163 1.92 ENST00000327367.4
SMAD3
SMAD family member 3
chr4_+_128703295 1.85 ENST00000296464.4
ENST00000508549.1
HSPA4L
heat shock 70kDa protein 4-like
chr4_+_20255123 1.79 ENST00000504154.1
ENST00000273739.5
SLIT2
slit homolog 2 (Drosophila)
chr6_+_127439749 1.68 ENST00000356698.4
RSPO3
R-spondin 3
chr1_-_201438282 1.67 ENST00000367311.3
ENST00000367309.1
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr9_+_118916082 1.61 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr11_+_69455855 1.59 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr2_+_112812778 1.55 ENST00000283206.4
TMEM87B
transmembrane protein 87B
chr7_-_83824169 1.54 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_+_66217911 1.52 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr1_+_209848749 1.51 ENST00000367029.4
G0S2
G0/G1switch 2
chr22_-_42017021 1.42 ENST00000263256.6
DESI1
desumoylating isopeptidase 1
chr20_-_3996036 1.39 ENST00000336095.6
RNF24
ring finger protein 24
chr1_-_57045228 1.28 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr16_+_50775948 1.27 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr17_+_40834580 1.26 ENST00000264638.4
CNTNAP1
contactin associated protein 1
chr5_-_141704566 1.25 ENST00000344120.4
ENST00000434127.2
SPRY4
sprouty homolog 4 (Drosophila)
chr15_+_66679155 1.20 ENST00000307102.5
MAP2K1
mitogen-activated protein kinase kinase 1
chr15_+_41245160 1.20 ENST00000444189.2
ENST00000446533.3
CHAC1
ChaC, cation transport regulator homolog 1 (E. coli)
chr6_+_11094266 1.17 ENST00000416247.2
SMIM13
small integral membrane protein 13
chr6_-_154831779 1.14 ENST00000607772.1
CNKSR3
CNKSR family member 3
chr5_-_95297678 1.11 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr12_+_4382917 1.09 ENST00000261254.3
CCND2
cyclin D2
chr16_+_56672571 1.08 ENST00000290705.8
MT1A
metallothionein 1A
chr15_+_59063478 1.07 ENST00000559228.1
ENST00000450403.2
FAM63B
family with sequence similarity 63, member B
chr1_+_28586006 1.06 ENST00000253063.3
SESN2
sestrin 2
chr4_+_25235597 1.04 ENST00000264864.6
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr2_+_26568965 1.01 ENST00000260585.7
ENST00000447170.1
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr11_+_118307179 1.01 ENST00000534358.1
ENST00000531904.2
ENST00000389506.5
ENST00000354520.4
KMT2A
lysine (K)-specific methyltransferase 2A
chr6_+_37137939 0.99 ENST00000373509.5
PIM1
pim-1 oncogene
chr2_+_26256938 0.97 ENST00000264710.4
RAB10
RAB10, member RAS oncogene family
chr14_+_70078303 0.95 ENST00000342745.4
KIAA0247
KIAA0247
chr8_-_141645645 0.94 ENST00000519980.1
ENST00000220592.5
AGO2
argonaute RISC catalytic component 2
chr1_-_156721502 0.94 ENST00000357325.5
HDGF
hepatoma-derived growth factor
chr1_+_184356188 0.93 ENST00000235307.6
C1orf21
chromosome 1 open reading frame 21
chr11_-_34379546 0.92 ENST00000435224.2
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr4_+_140222609 0.91 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr12_+_62654119 0.91 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15
ubiquitin specific peptidase 15
chr7_-_92463210 0.91 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr11_+_65082289 0.91 ENST00000279249.2
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr3_-_178790057 0.90 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr5_-_54830784 0.90 ENST00000264775.5
PPAP2A
phosphatidic acid phosphatase type 2A
chr9_+_132934835 0.90 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr7_-_98741642 0.90 ENST00000361368.2
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr10_+_101419187 0.90 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr8_+_104311059 0.89 ENST00000358755.4
ENST00000523739.1
ENST00000540287.1
FZD6
frizzled family receptor 6
chr9_-_95432536 0.88 ENST00000287996.3
IPPK
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr2_-_208030647 0.86 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr13_-_30169807 0.85 ENST00000380752.5
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr11_+_73087309 0.85 ENST00000064780.2
ENST00000545687.1
RELT
RELT tumor necrosis factor receptor
chr18_+_55102917 0.85 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr1_+_145438469 0.85 ENST00000369317.4
TXNIP
thioredoxin interacting protein
chr3_+_173116225 0.84 ENST00000457714.1
NLGN1
neuroligin 1
chr12_-_50101165 0.83 ENST00000352151.5
ENST00000335154.5
ENST00000293590.5
FMNL3
formin-like 3
chr3_-_48229846 0.81 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A
cell division cycle 25A
chr1_+_27561007 0.81 ENST00000319394.3
WDTC1
WD and tetratricopeptide repeats 1
chr3_+_10206545 0.81 ENST00000256458.4
IRAK2
interleukin-1 receptor-associated kinase 2
chr7_+_90032667 0.80 ENST00000496677.1
ENST00000287916.4
ENST00000535571.1
ENST00000394604.1
ENST00000394605.2
CLDN12
claudin 12
chr16_-_48644061 0.80 ENST00000262384.3
N4BP1
NEDD4 binding protein 1
chr4_-_153457197 0.79 ENST00000281708.4
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr22_+_39101728 0.77 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chr9_-_136857403 0.77 ENST00000406606.3
ENST00000371850.3
VAV2
vav 2 guanine nucleotide exchange factor
chr3_-_37217756 0.77 ENST00000440230.1
ENST00000421276.2
ENST00000421307.1
ENST00000354379.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr13_+_26828275 0.77 ENST00000381527.3
CDK8
cyclin-dependent kinase 8
chr12_-_53473136 0.76 ENST00000547837.1
ENST00000301463.4
SPRYD3
SPRY domain containing 3
chr5_-_16465901 0.76 ENST00000308683.2
ZNF622
zinc finger protein 622
chr5_-_160279207 0.76 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr2_+_73144604 0.74 ENST00000258106.6
EMX1
empty spiracles homeobox 1
chr17_+_26662730 0.72 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr5_+_67511524 0.72 ENST00000521381.1
ENST00000521657.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr3_-_39195037 0.71 ENST00000273153.5
CSRNP1
cysteine-serine-rich nuclear protein 1
chr14_+_32546485 0.71 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
ARHGAP5
Rho GTPase activating protein 5
chr22_+_45559722 0.70 ENST00000347635.4
ENST00000407019.2
ENST00000424634.1
ENST00000417702.1
ENST00000425733.2
ENST00000430547.1
NUP50
nucleoporin 50kDa
chr3_+_53195136 0.70 ENST00000394729.2
ENST00000330452.3
PRKCD
protein kinase C, delta
chr7_-_143105941 0.70 ENST00000275815.3
EPHA1
EPH receptor A1
chr2_-_161350305 0.70 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chrX_-_103087136 0.69 ENST00000243298.2
RAB9B
RAB9B, member RAS oncogene family
chr20_+_43374421 0.69 ENST00000372861.3
KCNK15
potassium channel, subfamily K, member 15
chr7_-_103629963 0.68 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN
reelin
chr8_-_37756972 0.67 ENST00000330843.4
ENST00000522727.1
ENST00000287263.4
RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr7_-_131241361 0.67 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL
podocalyxin-like
chr17_-_62658186 0.67 ENST00000262435.9
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr20_+_44486246 0.66 ENST00000255152.2
ENST00000454862.2
ZSWIM3
zinc finger, SWIM-type containing 3
chr2_+_73441350 0.66 ENST00000389501.4
SMYD5
SMYD family member 5
chr11_-_60929074 0.66 ENST00000301765.5
VPS37C
vacuolar protein sorting 37 homolog C (S. cerevisiae)
chr1_+_10271674 0.66 ENST00000377086.1
KIF1B
kinesin family member 1B
chr3_+_88188254 0.66 ENST00000309495.5
ZNF654
zinc finger protein 654
chr1_+_110453203 0.64 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr17_+_46184911 0.63 ENST00000580219.1
ENST00000452859.2
ENST00000393405.2
ENST00000439357.2
ENST00000359238.2
SNX11
sorting nexin 11
chr11_-_86666427 0.63 ENST00000531380.1
FZD4
frizzled family receptor 4
chrX_-_110513703 0.63 ENST00000324068.1
CAPN6
calpain 6
chr21_+_45285050 0.63 ENST00000291572.8
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr3_-_112218378 0.63 ENST00000334529.5
BTLA
B and T lymphocyte associated
chr6_+_43737939 0.63 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr1_-_244013384 0.62 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr8_+_25316489 0.62 ENST00000330560.3
CDCA2
cell division cycle associated 2
chr17_-_1395954 0.61 ENST00000359786.5
MYO1C
myosin IC
chr1_-_159869912 0.61 ENST00000368099.4
CCDC19
coiled-coil domain containing 19
chr2_+_210636697 0.61 ENST00000439458.1
ENST00000272845.6
UNC80
unc-80 homolog (C. elegans)
chr3_-_160283348 0.61 ENST00000334256.4
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr17_-_27916621 0.61 ENST00000225394.3
GIT1
G protein-coupled receptor kinase interacting ArfGAP 1
chr12_+_122242597 0.60 ENST00000267197.5
SETD1B
SET domain containing 1B
chr1_-_151300160 0.60 ENST00000368874.4
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
chr12_-_26278030 0.60 ENST00000242728.4
BHLHE41
basic helix-loop-helix family, member e41
chr12_+_12764773 0.60 ENST00000228865.2
CREBL2
cAMP responsive element binding protein-like 2
chr10_-_100995540 0.59 ENST00000370546.1
ENST00000404542.1
HPSE2
heparanase 2
chr9_-_27529726 0.59 ENST00000262244.5
MOB3B
MOB kinase activator 3B
chr20_-_45035223 0.58 ENST00000450812.1
ENST00000290246.6
ENST00000439931.2
ENST00000396391.1
ELMO2
engulfment and cell motility 2
chr17_+_21187976 0.58 ENST00000342679.4
MAP2K3
mitogen-activated protein kinase kinase 3
chr4_+_15004165 0.58 ENST00000538197.1
ENST00000541112.1
ENST00000442003.2
CPEB2
cytoplasmic polyadenylation element binding protein 2
chr11_-_72853091 0.58 ENST00000311172.7
ENST00000409314.1
FCHSD2
FCH and double SH3 domains 2
chr14_+_33408449 0.58 ENST00000346562.2
ENST00000341321.4
ENST00000548645.1
ENST00000356141.4
ENST00000357798.5
NPAS3
neuronal PAS domain protein 3
chr17_-_56595196 0.58 ENST00000579921.1
ENST00000579925.1
ENST00000323456.5
MTMR4
myotubularin related protein 4
chr20_+_62526467 0.58 ENST00000369911.2
ENST00000360864.4
DNAJC5
DnaJ (Hsp40) homolog, subfamily C, member 5
chr6_+_7107999 0.57 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chr15_+_98503922 0.57 ENST00000268042.6
ARRDC4
arrestin domain containing 4
chr19_+_49622646 0.57 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr11_-_65667884 0.57 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr18_-_61034743 0.57 ENST00000406396.3
KDSR
3-ketodihydrosphingosine reductase
chr9_+_102668915 0.56 ENST00000259400.6
ENST00000531035.1
ENST00000525640.1
ENST00000534052.1
ENST00000526607.1
STX17
syntaxin 17
chr7_+_6144514 0.56 ENST00000306177.5
ENST00000465073.2
USP42
ubiquitin specific peptidase 42
chr1_-_156786530 0.56 ENST00000368198.3
SH2D2A
SH2 domain containing 2A
chr3_+_196594727 0.56 ENST00000445299.2
ENST00000323460.5
ENST00000419026.1
SENP5
SUMO1/sentrin specific peptidase 5
chr11_+_46639071 0.55 ENST00000580238.1
ENST00000581416.1
ENST00000529655.1
ENST00000533325.1
ENST00000581438.1
ENST00000583249.1
ENST00000530500.1
ENST00000526508.1
ENST00000578626.1
ENST00000577256.1
ENST00000524625.1
ENST00000582547.1
ENST00000359513.4
ENST00000528494.1
ATG13
autophagy related 13
chr19_-_17799008 0.55 ENST00000519716.2
UNC13A
unc-13 homolog A (C. elegans)
chr3_+_140770183 0.55 ENST00000310546.2
SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr17_+_36861735 0.54 ENST00000378137.5
ENST00000325718.7
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr14_-_77279153 0.53 ENST00000251089.2
ANGEL1
angel homolog 1 (Drosophila)
chr12_+_21654714 0.53 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
GOLT1B
golgi transport 1B
chr5_+_125758813 0.53 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr14_+_23775971 0.52 ENST00000250405.5
BCL2L2
BCL2-like 2
chr20_+_30865429 0.52 ENST00000375712.3
KIF3B
kinesin family member 3B
chr11_-_118023490 0.52 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr3_-_122233723 0.52 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr6_-_90062543 0.51 ENST00000435041.2
UBE2J1
ubiquitin-conjugating enzyme E2, J1
chr2_-_46385 0.51 ENST00000327669.4
FAM110C
family with sequence similarity 110, member C
chr3_-_42846021 0.51 ENST00000321331.7
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr16_+_19125252 0.51 ENST00000566735.1
ENST00000381440.3
ITPRIPL2
inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr11_-_46142948 0.51 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr1_-_22469459 0.51 ENST00000290167.6
WNT4
wingless-type MMTV integration site family, member 4
chr16_-_73082274 0.50 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr9_-_37576226 0.49 ENST00000432825.2
FBXO10
F-box protein 10
chr1_+_171454659 0.49 ENST00000367742.3
ENST00000338920.4
PRRC2C
proline-rich coiled-coil 2C
chr5_+_167718604 0.49 ENST00000265293.4
WWC1
WW and C2 domain containing 1
chr15_+_69706585 0.49 ENST00000559279.1
ENST00000395392.2
KIF23
kinesin family member 23
chr4_+_184826418 0.48 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chr1_+_26737253 0.48 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr14_+_55034599 0.48 ENST00000392067.3
ENST00000357634.3
SAMD4A
sterile alpha motif domain containing 4A
chr8_-_122653630 0.48 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr19_-_49222956 0.47 ENST00000599703.1
ENST00000318083.6
ENST00000419611.1
ENST00000377367.3
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr1_+_182992545 0.46 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr3_-_48130707 0.46 ENST00000360240.6
ENST00000383737.4
MAP4
microtubule-associated protein 4
chr22_-_17602200 0.46 ENST00000399875.1
CECR6
cat eye syndrome chromosome region, candidate 6
chr17_-_27621125 0.45 ENST00000579665.1
ENST00000225388.4
NUFIP2
nuclear fragile X mental retardation protein interacting protein 2
chr14_-_104029013 0.45 ENST00000299204.4
ENST00000557666.1
BAG5
BCL2-associated athanogene 5
chr1_-_6321035 0.45 ENST00000377893.2
GPR153
G protein-coupled receptor 153
chr12_-_129308487 0.45 ENST00000266771.5
SLC15A4
solute carrier family 15 (oligopeptide transporter), member 4
chr10_+_81107216 0.45 ENST00000394579.3
ENST00000225174.3
PPIF
peptidylprolyl isomerase F
chr5_-_74326724 0.44 ENST00000322348.4
GCNT4
glucosaminyl (N-acetyl) transferase 4, core 2
chr8_+_61591337 0.44 ENST00000423902.2
CHD7
chromodomain helicase DNA binding protein 7
chr7_-_994302 0.44 ENST00000265846.5
ADAP1
ArfGAP with dual PH domains 1
chr17_+_4901199 0.43 ENST00000320785.5
ENST00000574165.1
KIF1C
kinesin family member 1C
chr3_+_183903811 0.43 ENST00000429586.2
ENST00000292808.5
ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr13_-_27745936 0.43 ENST00000282344.6
USP12
ubiquitin specific peptidase 12
chr14_+_75348592 0.43 ENST00000334220.4
DLST
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr12_+_54891495 0.43 ENST00000293373.6
NCKAP1L
NCK-associated protein 1-like
chr15_+_59730348 0.42 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chr6_+_30539153 0.42 ENST00000326195.8
ENST00000376545.3
ENST00000396515.4
ENST00000441867.1
ENST00000468958.1
ABCF1
ATP-binding cassette, sub-family F (GCN20), member 1
chrX_+_53111541 0.41 ENST00000375442.4
ENST00000579390.1
TSPYL2
TSPY-like 2
chr21_-_36260980 0.41 ENST00000344691.4
ENST00000358356.5
RUNX1
runt-related transcription factor 1
chr1_+_47799446 0.41 ENST00000371873.5
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr1_-_52831796 0.41 ENST00000284376.3
ENST00000438831.1
ENST00000371586.2
CC2D1B
coiled-coil and C2 domain containing 1B
chr20_-_31071239 0.41 ENST00000359676.5
C20orf112
chromosome 20 open reading frame 112
chr2_-_73340146 0.40 ENST00000258098.6
RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr11_-_65686586 0.40 ENST00000438576.2
C11orf68
chromosome 11 open reading frame 68
chr13_-_50367057 0.40 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr11_+_9406169 0.40 ENST00000379719.3
ENST00000527431.1
IPO7
importin 7
chr5_-_45696253 0.40 ENST00000303230.4
HCN1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr14_-_105487381 0.40 ENST00000392590.3
ENST00000336219.3
CDCA4
cell division cycle associated 4
chrX_+_152599604 0.39 ENST00000370251.3
ENST00000421401.3
ZNF275
zinc finger protein 275
chr22_-_41985865 0.39 ENST00000216259.7
PMM1
phosphomannomutase 1
chr18_-_65184217 0.39 ENST00000310045.7
DSEL
dermatan sulfate epimerase-like
chr18_+_10526008 0.39 ENST00000542979.1
ENST00000322897.6
NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr18_+_158513 0.39 ENST00000400266.3
ENST00000580410.1
ENST00000383589.2
ENST00000261601.7
USP14
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chr4_-_79860506 0.39 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
PAQR3
progestin and adipoQ receptor family member III
chr7_+_36429409 0.38 ENST00000265748.2
ANLN
anillin, actin binding protein
chr5_+_140345820 0.38 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr12_-_77459306 0.38 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
E2F7
E2F transcription factor 7
chr7_+_91875508 0.38 ENST00000265742.3
ANKIB1
ankyrin repeat and IBR domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of AGCAGCA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
1.0 3.0 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.9 2.6 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.9 2.6 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.6 1.8 GO:1902623 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) corticospinal neuron axon guidance(GO:0021966) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.5 5.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.4 1.3 GO:1990108 protein linear deubiquitination(GO:1990108)
0.4 2.5 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.4 1.9 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.3 1.0 GO:0097051 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.3 0.9 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.3 1.5 GO:0048880 sensory system development(GO:0048880)
0.3 3.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.3 0.3 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.3 0.9 GO:1902534 single-organism membrane invagination(GO:1902534)
0.3 0.3 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.3 2.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.3 2.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 1.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.3 1.0 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 0.9 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.2 0.2 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.2 0.9 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2 0.7 GO:0097114 NMDA glutamate receptor clustering(GO:0097114)
0.2 2.9 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.2 0.9 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 0.4 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 0.8 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.2 0.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 0.6 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 1.2 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.2 0.7 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.2 0.7 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.2 0.9 GO:1903826 arginine transmembrane transport(GO:1903826)
0.2 0.5 GO:0061183 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) renal vesicle induction(GO:0072034)
0.2 0.7 GO:1904647 response to rotenone(GO:1904647)
0.2 0.5 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2 2.5 GO:0060413 atrial septum morphogenesis(GO:0060413)
0.2 0.8 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 1.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 1.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.2 1.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.2 2.1 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 0.4 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 2.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.5 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.9 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.4 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.6 GO:1904141 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.1 0.4 GO:1904172 regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.1 0.4 GO:0071930 positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.5 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.8 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.4 GO:0003186 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186)
0.1 0.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.3 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.1 0.3 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.4 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 0.4 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.3 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.1 GO:0015817 histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.9 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 1.0 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 0.3 GO:1904339 superior temporal gyrus development(GO:0071109) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.6 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.3 GO:0021503 neural fold bending(GO:0021503)
0.1 1.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.4 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.3 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.3 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.5 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.2 GO:1901859 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.1 0.3 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.3 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.6 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.4 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.3 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.1 0.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.2 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.9 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 1.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.2 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.5 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.2 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.1 GO:0071484 cellular response to light intensity(GO:0071484)
0.1 0.2 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 1.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.2 GO:2001035 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 0.5 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.6 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.6 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.4 GO:0006857 oligopeptide transport(GO:0006857)
0.0 1.6 GO:0019054 modulation by virus of host process(GO:0019054)
0.0 0.8 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.8 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.2 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.3 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.4 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.4 GO:0035726 myeloid progenitor cell differentiation(GO:0002318) common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.4 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 1.1 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.9 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.9 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.3 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.3 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.3 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 2.0 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.3 GO:0060613 fat pad development(GO:0060613)
0.0 0.4 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.2 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 1.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.4 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.3 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
0.0 0.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.5 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0 0.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.6 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.3 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.3 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0 0.3 GO:0048617 positive regulation of activin receptor signaling pathway(GO:0032927) embryonic foregut morphogenesis(GO:0048617)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.9 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.7 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 0.2 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.5 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.9 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 1.4 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.6 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.9 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.6 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.2 GO:0015793 glycerol transport(GO:0015793) urea transport(GO:0015840)
0.0 0.4 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.2 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.4 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.3 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.3 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.2 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.3 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 1.6 GO:0034644 cellular response to UV(GO:0034644)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.0 GO:0008355 olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.0 0.1 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.4 GO:0051642 centrosome localization(GO:0051642)
0.0 0.3 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.3 GO:0031297 replication fork processing(GO:0031297) regulation of DNA damage checkpoint(GO:2000001)
0.0 0.3 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.2 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0045060 negative thymic T cell selection(GO:0045060)
0.0 0.5 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.0 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.8 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 0.3 GO:0009299 mRNA transcription(GO:0009299)
0.0 1.1 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.7 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.7 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.4 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.0 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.3 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.3 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.0 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 1.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 0.7 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2 0.5 GO:0005873 plus-end kinesin complex(GO:0005873)
0.2 0.7 GO:1990742 microvesicle(GO:1990742)
0.2 0.6 GO:0045160 myosin I complex(GO:0045160)
0.2 1.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 1.6 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.4 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.4 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.5 GO:0043260 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.1 0.9 GO:0031415 NatA complex(GO:0031415)
0.1 0.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.6 GO:0044305 calyx of Held(GO:0044305)
0.1 0.6 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.5 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.3 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 1.3 GO:0033010 paranodal junction(GO:0033010)
0.1 0.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.2 GO:0016938 kinesin I complex(GO:0016938)
0.1 0.6 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.7 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0071817 MMXD complex(GO:0071817)
0.0 0.9 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.3 GO:0098560 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.6 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.2 GO:0002079 inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.0 0.2 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 1.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.3 GO:0031298 replication fork protection complex(GO:0031298)
0.0 2.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.3 GO:0097542 ciliary tip(GO:0097542)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 2.2 GO:0005643 nuclear pore(GO:0005643)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 1.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.2 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 2.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.4 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.5 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.7 2.6 GO:0005292 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.5 2.7 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.4 1.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.4 2.4 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.4 1.9 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.4 1.5 GO:0035501 MH1 domain binding(GO:0035501)
0.3 1.0 GO:0045322 unmethylated CpG binding(GO:0045322)
0.3 0.9 GO:0098808 mRNA cap binding(GO:0098808)
0.3 0.9 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 2.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 0.9 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 1.8 GO:0043237 laminin-1 binding(GO:0043237) Roundabout binding(GO:0048495)
0.2 2.6 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.2 0.7 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.2 3.0 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.2 0.9 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.4 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.6 GO:0030305 heparanase activity(GO:0030305)
0.1 1.0 GO:0070728 leucine binding(GO:0070728)
0.1 0.7 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.7 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.9 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.4 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 1.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.8 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 2.8 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.6 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.4 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.8 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.7 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.6 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 1.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 3.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.1 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.2 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 2.2 GO:0005109 frizzled binding(GO:0005109)
0.0 1.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.6 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 1.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.5 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0031071 cysteine desulfurase activity(GO:0031071)
0.0 1.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.8 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.4 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.3 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.7 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.7 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 1.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 2.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.8 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 6.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 2.9 PID IL27 PATHWAY IL27-mediated signaling events
0.1 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 2.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 0.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.0 PID IL5 PATHWAY IL5-mediated signaling events
0.1 1.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.9 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 2.7 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.9 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.8 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.8 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 2.2 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 3.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.2 PID IGF1 PATHWAY IGF1 pathway
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 8.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 4.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 0.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.7 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.0 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 3.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.3 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 2.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.8 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.3 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 2.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.2 REACTOME KINESINS Genes involved in Kinesins
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 2.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 2.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis