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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for AGCUUAU

Z-value: 0.47

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miRNA associated with seed AGCUUAU

NamemiRBASE accession
hsa-miR-21-5p
MIMAT0000076
hsa-miR-590-5p
MIMAT0003258

Activity profile of AGCUUAU motif

Sorted Z-values of AGCUUAU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_61547894 1.28 ENST00000403491.3
NFIA
nuclear factor I/A
chr10_+_112631547 1.12 ENST00000280154.7
ENST00000393104.2
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr9_-_14314066 1.10 ENST00000397575.3
NFIB
nuclear factor I/B
chr1_+_178694300 0.74 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr2_-_43453734 0.68 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr4_-_102268628 0.64 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr20_-_23030296 0.59 ENST00000377103.2
THBD
thrombomodulin
chr8_-_9008206 0.58 ENST00000310455.3
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr3_-_18466787 0.54 ENST00000338745.6
ENST00000450898.1
SATB1
SATB homeobox 1
chr5_+_56111361 0.52 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr9_+_36036430 0.52 ENST00000377966.3
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr22_+_33197683 0.50 ENST00000266085.6
TIMP3
TIMP metallopeptidase inhibitor 3
chr1_+_2160134 0.45 ENST00000378536.4
SKI
v-ski avian sarcoma viral oncogene homolog
chr8_+_98881268 0.45 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2
matrilin 2
chr12_+_48516357 0.40 ENST00000549022.1
ENST00000547587.1
ENST00000312352.7
PFKM
phosphofructokinase, muscle
chr1_+_203274639 0.37 ENST00000290551.4
BTG2
BTG family, member 2
chr2_+_47630108 0.37 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
MSH2
mutS homolog 2
chrX_-_24045303 0.37 ENST00000328046.8
KLHL15
kelch-like family member 15
chr3_+_110790590 0.37 ENST00000485303.1
PVRL3
poliovirus receptor-related 3
chr4_+_4861385 0.35 ENST00000382723.4
MSX1
msh homeobox 1
chr8_-_81787006 0.32 ENST00000327835.3
ZNF704
zinc finger protein 704
chr16_+_12070567 0.31 ENST00000566228.1
SNX29
sorting nexin 29
chr5_+_170846640 0.30 ENST00000274625.5
FGF18
fibroblast growth factor 18
chr13_+_73632897 0.30 ENST00000377687.4
KLF5
Kruppel-like factor 5 (intestinal)
chr3_+_159706537 0.29 ENST00000305579.2
ENST00000480787.1
ENST00000466512.1
IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr4_+_113152881 0.27 ENST00000274000.5
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr11_+_101981169 0.26 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
YAP1
Yes-associated protein 1
chrX_-_18372792 0.24 ENST00000251900.4
SCML2
sex comb on midleg-like 2 (Drosophila)
chr5_-_38595498 0.22 ENST00000263409.4
LIFR
leukemia inhibitory factor receptor alpha
chr12_-_9913489 0.22 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr2_-_85581701 0.21 ENST00000295802.4
RETSAT
retinol saturase (all-trans-retinol 13,14-reductase)
chr8_-_22550815 0.21 ENST00000317216.2
EGR3
early growth response 3
chr16_+_69221028 0.19 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr1_+_33005020 0.19 ENST00000373510.4
ENST00000316459.4
ZBTB8A
zinc finger and BTB domain containing 8A
chr5_-_54281491 0.18 ENST00000381405.4
ESM1
endothelial cell-specific molecule 1
chr6_+_148663729 0.17 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr2_-_180129484 0.17 ENST00000428443.3
SESTD1
SEC14 and spectrin domains 1
chr4_+_38665810 0.17 ENST00000261438.5
ENST00000514033.1
KLF3
Kruppel-like factor 3 (basic)
chr16_+_4364762 0.17 ENST00000262366.3
GLIS2
GLIS family zinc finger 2
chr4_-_89744457 0.17 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr4_+_144257915 0.16 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr12_-_12419703 0.16 ENST00000543091.1
ENST00000261349.4
LRP6
low density lipoprotein receptor-related protein 6
chr14_+_57735614 0.15 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr1_+_154377669 0.15 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr21_-_39870339 0.15 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr5_+_10353780 0.15 ENST00000449913.2
ENST00000503788.1
ENST00000274140.5
MARCH6
membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
chr8_-_10697281 0.15 ENST00000524114.1
ENST00000553390.1
ENST00000554914.1
PINX1
SOX7
SOX7
PIN2/TERF1 interacting, telomerase inhibitor 1
SRY (sex determining region Y)-box 7
Transcription factor SOX-7; Uncharacterized protein; cDNA FLJ58508, highly similar to Transcription factor SOX-7
chr9_+_133971909 0.15 ENST00000247291.3
ENST00000372302.1
ENST00000372300.1
ENST00000372298.1
AIF1L
allograft inflammatory factor 1-like
chr17_+_58755184 0.14 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr14_+_57046500 0.14 ENST00000261556.6
TMEM260
transmembrane protein 260
chr5_-_150080472 0.13 ENST00000521464.1
ENST00000518917.1
ENST00000447771.2
ENST00000540000.1
ENST00000199814.4
RBM22
RNA binding motif protein 22
chr10_-_12238071 0.13 ENST00000491614.1
ENST00000537776.1
NUDT5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr17_-_30669138 0.12 ENST00000225805.4
ENST00000577809.1
C17orf75
chromosome 17 open reading frame 75
chr3_-_52713729 0.12 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
PBRM1
polybromo 1
chr11_-_94964354 0.12 ENST00000536441.1
SESN3
sestrin 3
chr3_+_152017181 0.12 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1
muscleblind-like splicing regulator 1
chr11_+_120207787 0.12 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr2_+_45878790 0.12 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr11_-_130786400 0.11 ENST00000265909.4
SNX19
sorting nexin 19
chr2_-_218808771 0.11 ENST00000449814.1
ENST00000171887.4
TNS1
tensin 1
chr3_-_72496035 0.11 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr10_-_14590644 0.11 ENST00000378470.1
FAM107B
family with sequence similarity 107, member B
chr2_+_20646824 0.11 ENST00000272233.4
RHOB
ras homolog family member B
chr12_+_5019061 0.10 ENST00000382545.3
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr2_+_86947296 0.10 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr2_+_170683942 0.10 ENST00000272793.5
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr10_+_72164135 0.10 ENST00000373218.4
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr8_-_10588010 0.09 ENST00000304501.1
SOX7
SRY (sex determining region Y)-box 7
chrX_-_20284958 0.09 ENST00000379565.3
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr9_-_16870704 0.09 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chr22_+_40573921 0.09 ENST00000454349.2
ENST00000335727.9
TNRC6B
trinucleotide repeat containing 6B
chr15_-_102029873 0.09 ENST00000348070.1
ENST00000358417.3
ENST00000344273.2
PCSK6
proprotein convertase subtilisin/kexin type 6
chr10_-_3827417 0.08 ENST00000497571.1
ENST00000542957.1
KLF6
Kruppel-like factor 6
chr14_-_31676964 0.08 ENST00000553700.1
HECTD1
HECT domain containing E3 ubiquitin protein ligase 1
chr2_+_228678550 0.07 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr7_+_102715315 0.07 ENST00000428183.2
ENST00000323716.3
ENST00000441711.2
ENST00000454559.1
ENST00000425331.1
ENST00000541300.1
ARMC10
armadillo repeat containing 10
chr16_-_20911641 0.07 ENST00000564349.1
ENST00000324344.4
ERI2
DCUN1D3
ERI1 exoribonuclease family member 2
DCN1, defective in cullin neddylation 1, domain containing 3
chr18_+_67956135 0.07 ENST00000397942.3
SOCS6
suppressor of cytokine signaling 6
chr1_-_214724566 0.07 ENST00000366956.5
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr18_-_72921303 0.07 ENST00000322342.3
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr19_+_14492247 0.07 ENST00000357355.3
ENST00000592261.2
ENST00000242786.5
CD97
CD97 molecule
chr1_-_153895377 0.07 ENST00000368655.4
GATAD2B
GATA zinc finger domain containing 2B
chr7_+_8008418 0.07 ENST00000223145.5
GLCCI1
glucocorticoid induced transcript 1
chr6_+_119215308 0.06 ENST00000229595.5
ASF1A
anti-silencing function 1A histone chaperone
chrX_+_123095155 0.06 ENST00000371160.1
ENST00000435103.1
STAG2
stromal antigen 2
chr20_+_62371206 0.06 ENST00000266077.2
SLC2A4RG
SLC2A4 regulator
chr15_-_38856836 0.06 ENST00000450598.2
ENST00000559830.1
ENST00000558164.1
ENST00000310803.5
RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr5_+_154238096 0.06 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
CNOT8
CCR4-NOT transcription complex, subunit 8
chr16_+_69599861 0.06 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr5_+_86564739 0.05 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr7_-_30029367 0.05 ENST00000242059.5
SCRN1
secernin 1
chrX_+_100805496 0.05 ENST00000372829.3
ARMCX1
armadillo repeat containing, X-linked 1
chr10_+_70320413 0.05 ENST00000373644.4
TET1
tet methylcytosine dioxygenase 1
chr6_-_159466136 0.05 ENST00000367066.3
ENST00000326965.6
TAGAP
T-cell activation RhoGTPase activating protein
chr15_+_66161871 0.05 ENST00000569896.1
RAB11A
RAB11A, member RAS oncogene family
chr17_+_38278530 0.05 ENST00000398532.4
MSL1
male-specific lethal 1 homolog (Drosophila)
chr16_-_75498553 0.05 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
TMEM170A
RP11-77K12.1
transmembrane protein 170A
Uncharacterized protein
chr2_-_201936302 0.04 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
FAM126B
family with sequence similarity 126, member B
chr1_-_115632035 0.04 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
TSPAN2
tetraspanin 2
chr4_+_86396265 0.04 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr9_-_123476719 0.04 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr17_+_61627814 0.04 ENST00000310827.4
ENST00000431926.1
ENST00000415273.2
DCAF7
DDB1 and CUL4 associated factor 7
chr17_+_36452989 0.04 ENST00000312513.5
ENST00000582535.1
MRPL45
mitochondrial ribosomal protein L45
chr15_-_55881135 0.04 ENST00000302000.6
PYGO1
pygopus family PHD finger 1
chr3_+_28283069 0.04 ENST00000466830.1
ENST00000423894.1
CMC1
C-x(9)-C motif containing 1
chr15_-_75249793 0.04 ENST00000322177.5
RPP25
ribonuclease P/MRP 25kDa subunit
chr14_+_64854958 0.04 ENST00000555709.2
ENST00000554739.1
ENST00000554768.1
ENST00000216605.8
MTHFD1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
chr2_-_64371546 0.03 ENST00000358912.4
PELI1
pellino E3 ubiquitin protein ligase 1
chr17_-_77813186 0.03 ENST00000448310.1
ENST00000269397.4
CBX4
chromobox homolog 4
chr7_-_113559104 0.03 ENST00000284601.3
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr10_+_76871454 0.03 ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr5_-_32313019 0.03 ENST00000280285.5
ENST00000264934.5
MTMR12
myotubularin related protein 12
chr11_-_110167352 0.03 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
RDX
radixin
chr12_-_123011536 0.03 ENST00000331738.7
ENST00000354654.2
RSRC2
arginine/serine-rich coiled-coil 2
chr7_+_11013491 0.03 ENST00000403050.3
ENST00000445996.2
PHF14
PHD finger protein 14
chr20_+_277737 0.03 ENST00000382352.3
ZCCHC3
zinc finger, CCHC domain containing 3
chr10_+_75757863 0.03 ENST00000372755.3
ENST00000211998.4
ENST00000417648.2
VCL
vinculin
chr1_+_222791417 0.02 ENST00000344922.5
ENST00000344441.6
ENST00000344507.1
MIA3
melanoma inhibitory activity family, member 3
chr12_+_22778009 0.02 ENST00000266517.4
ENST00000335148.3
ETNK1
ethanolamine kinase 1
chr20_+_56884752 0.02 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr15_-_42840961 0.02 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
LRRC57
leucine rich repeat containing 57
chr11_-_44331679 0.02 ENST00000329255.3
ALX4
ALX homeobox 4
chr12_+_53848505 0.02 ENST00000552819.1
ENST00000455667.3
PCBP2
poly(rC) binding protein 2
chr1_-_245027833 0.02 ENST00000444376.2
HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr5_+_172483347 0.02 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF
CREB3 regulatory factor
chr5_-_89770582 0.02 ENST00000316610.6
MBLAC2
metallo-beta-lactamase domain containing 2
chr2_+_70314579 0.01 ENST00000303577.5
PCBP1
poly(rC) binding protein 1
chr2_-_198650037 0.01 ENST00000392296.4
BOLL
boule-like RNA-binding protein
chr13_+_28813645 0.01 ENST00000282391.5
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr16_-_2246436 0.01 ENST00000343516.6
CASKIN1
CASK interacting protein 1
chr1_-_19283163 0.01 ENST00000455833.2
IFFO2
intermediate filament family orphan 2
chr8_-_117886955 0.01 ENST00000297338.2
RAD21
RAD21 homolog (S. pombe)
chr8_-_41909496 0.01 ENST00000265713.2
ENST00000406337.1
ENST00000396930.3
ENST00000485568.1
ENST00000426524.1
KAT6A
K(lysine) acetyltransferase 6A
chr2_-_69870835 0.00 ENST00000409085.4
ENST00000406297.3
AAK1
AP2 associated kinase 1
chr1_+_64239657 0.00 ENST00000371080.1
ENST00000371079.1
ROR1
receptor tyrosine kinase-like orphan receptor 1
chr17_+_60536002 0.00 ENST00000582809.1
TLK2
tousled-like kinase 2
chr1_+_224301787 0.00 ENST00000366862.5
ENST00000424254.2
FBXO28
F-box protein 28
chr1_+_36273743 0.00 ENST00000373210.3
AGO4
argonaute RISC catalytic component 4
chr4_+_81951957 0.00 ENST00000282701.2
BMP3
bone morphogenetic protein 3
chr16_-_4897266 0.00 ENST00000591451.1
ENST00000436648.5
ENST00000381983.3
ENST00000588297.1
ENST00000321919.9
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)

Network of associatons between targets according to the STRING database.

First level regulatory network of AGCUUAU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0036446 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.2 0.6 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.2 0.7 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.2 1.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.4 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.5 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.4 GO:0090427 activation of meiosis(GO:0090427)
0.1 0.4 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.3 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 0.2 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.1 0.4 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.1 0.5 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.1 0.4 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.5 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.2 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.6 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 1.2 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.3 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.3 GO:0002839 positive regulation of response to tumor cell(GO:0002836) positive regulation of immune response to tumor cell(GO:0002839) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.2 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:1904751 positive regulation of telomeric DNA binding(GO:1904744) positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.0 GO:2000791 regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.3 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455) neurotrophin production(GO:0032898)
0.0 0.0 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.2 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.2 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 1.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.6 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.2 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.4 GO:0000404 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.2 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 0.2 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 0.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.3 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.5 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR