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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for AGUGGUU

Z-value: 0.37

Motif logo

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miRNA associated with seed AGUGGUU

NamemiRBASE accession
hsa-miR-140-5p
MIMAT0000431

Activity profile of AGUGGUU motif

Sorted Z-values of AGUGGUU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_141704566 0.82 ENST00000344120.4
ENST00000434127.2
SPRY4
sprouty homolog 4 (Drosophila)
chr20_+_6748311 0.77 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr8_+_81397876 0.65 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr12_-_111021110 0.61 ENST00000354300.3
PPTC7
PTC7 protein phosphatase homolog (S. cerevisiae)
chr9_-_73029540 0.59 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr20_-_10654639 0.44 ENST00000254958.5
JAG1
jagged 1
chr7_-_98741642 0.42 ENST00000361368.2
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr8_-_80680078 0.41 ENST00000337919.5
ENST00000354724.3
HEY1
hes-related family bHLH transcription factor with YRPW motif 1
chr6_+_4890226 0.41 ENST00000343762.5
CDYL
chromodomain protein, Y-like
chr7_-_32931387 0.40 ENST00000304056.4
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr8_-_141645645 0.39 ENST00000519980.1
ENST00000220592.5
AGO2
argonaute RISC catalytic component 2
chr8_-_8751068 0.37 ENST00000276282.6
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chr17_-_53499310 0.37 ENST00000262065.3
MMD
monocyte to macrophage differentiation-associated
chr12_-_96794143 0.34 ENST00000543119.2
CDK17
cyclin-dependent kinase 17
chr14_+_70078303 0.34 ENST00000342745.4
KIAA0247
KIAA0247
chr9_+_101867359 0.32 ENST00000374994.4
TGFBR1
transforming growth factor, beta receptor 1
chr15_-_42264702 0.31 ENST00000220325.4
EHD4
EH-domain containing 4
chr12_+_45609893 0.31 ENST00000320560.8
ANO6
anoctamin 6
chr9_+_112810878 0.30 ENST00000434623.2
ENST00000374525.1
AKAP2
A kinase (PRKA) anchor protein 2
chr17_-_33448468 0.28 ENST00000591723.1
ENST00000593039.1
ENST00000587405.1
RAD51L3-RFFL
RAD51D
Uncharacterized protein
RAD51 paralog D
chr6_-_90062543 0.27 ENST00000435041.2
UBE2J1
ubiquitin-conjugating enzyme E2, J1
chrX_-_154563889 0.27 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr17_+_18218587 0.26 ENST00000406438.3
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr21_-_15755446 0.26 ENST00000544452.1
ENST00000285667.3
HSPA13
heat shock protein 70kDa family, member 13
chr6_+_41040678 0.24 ENST00000341376.6
ENST00000353205.5
NFYA
nuclear transcription factor Y, alpha
chr9_-_115095883 0.23 ENST00000450374.1
ENST00000374255.2
ENST00000334318.6
ENST00000374257.1
PTBP3
polypyrimidine tract binding protein 3
chr9_+_112542572 0.22 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr20_-_30310336 0.22 ENST00000434194.1
ENST00000376062.2
BCL2L1
BCL2-like 1
chr6_+_37225540 0.22 ENST00000373491.3
TBC1D22B
TBC1 domain family, member 22B
chr6_-_88411911 0.21 ENST00000257787.5
AKIRIN2
akirin 2
chr1_+_182992545 0.20 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr19_+_11200038 0.20 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
LDLR
low density lipoprotein receptor
chr1_-_182361327 0.19 ENST00000331872.6
ENST00000311223.5
GLUL
glutamate-ammonia ligase
chr5_-_16936340 0.19 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr15_-_48937982 0.19 ENST00000316623.5
FBN1
fibrillin 1
chr5_+_14143728 0.19 ENST00000344204.4
ENST00000537187.1
TRIO
trio Rho guanine nucleotide exchange factor
chr5_+_149887672 0.19 ENST00000261797.6
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr15_-_23086394 0.18 ENST00000337435.4
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chrX_+_70752917 0.18 ENST00000373719.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr3_-_42623428 0.18 ENST00000423701.2
ENST00000420163.1
ENST00000416880.1
ENST00000536332.1
ENST00000264454.3
ENST00000273156.7
SEC22C
SEC22 vesicle trafficking protein homolog C (S. cerevisiae)
chr6_+_43737939 0.18 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr16_-_20911641 0.17 ENST00000564349.1
ENST00000324344.4
ERI2
DCUN1D3
ERI1 exoribonuclease family member 2
DCN1, defective in cullin neddylation 1, domain containing 3
chr20_-_48770174 0.17 ENST00000341698.2
TMEM189-UBE2V1
TMEM189-UBE2V1 readthrough
chr10_+_60028818 0.16 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr8_+_38854418 0.16 ENST00000481513.1
ENST00000487273.2
ADAM9
ADAM metallopeptidase domain 9
chr4_-_146859623 0.16 ENST00000379448.4
ENST00000513320.1
ZNF827
zinc finger protein 827
chr20_-_4804244 0.16 ENST00000379400.3
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr18_-_45456930 0.15 ENST00000262160.6
ENST00000587269.1
SMAD2
SMAD family member 2
chr17_-_38020392 0.15 ENST00000346872.3
ENST00000439167.2
ENST00000377945.3
ENST00000394189.2
ENST00000377944.3
ENST00000377958.2
ENST00000535189.1
ENST00000377952.2
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr2_+_26256938 0.15 ENST00000264710.4
RAB10
RAB10, member RAS oncogene family
chr2_+_242255275 0.15 ENST00000391971.2
SEPT2
septin 2
chr2_-_213403565 0.15 ENST00000342788.4
ENST00000436443.1
ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr9_-_95432536 0.14 ENST00000287996.3
IPPK
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr14_-_75330537 0.14 ENST00000556084.2
ENST00000556489.2
ENST00000445876.1
PROX2
prospero homeobox 2
chr3_-_52713729 0.14 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
PBRM1
polybromo 1
chr12_-_498620 0.14 ENST00000399788.2
ENST00000382815.4
KDM5A
lysine (K)-specific demethylase 5A
chr3_+_152879985 0.14 ENST00000323534.2
RAP2B
RAP2B, member of RAS oncogene family
chr5_+_65222299 0.14 ENST00000284037.5
ERBB2IP
erbb2 interacting protein
chr22_-_36784035 0.14 ENST00000216181.5
MYH9
myosin, heavy chain 9, non-muscle
chrX_-_77395186 0.14 ENST00000341864.5
TAF9B
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
chr18_-_57027194 0.13 ENST00000251047.5
LMAN1
lectin, mannose-binding, 1
chr17_-_60142609 0.13 ENST00000397786.2
MED13
mediator complex subunit 13
chr20_-_48729670 0.13 ENST00000371657.5
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr10_+_126490354 0.13 ENST00000298492.5
FAM175B
family with sequence similarity 175, member B
chr7_-_139876812 0.13 ENST00000397560.2
JHDM1D
lysine (K)-specific demethylase 7A
chr7_+_2671568 0.13 ENST00000258796.7
TTYH3
tweety family member 3
chr2_-_178128528 0.13 ENST00000397063.4
ENST00000421929.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr9_+_132934835 0.12 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr1_+_101702417 0.12 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr14_-_82000140 0.12 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr5_-_168006591 0.11 ENST00000239231.6
PANK3
pantothenate kinase 3
chr1_-_68299130 0.11 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr10_-_104262426 0.11 ENST00000487599.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr4_-_54930790 0.11 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr9_+_98534605 0.11 ENST00000600140.1
DKFZP434H0512
Protein LOC100506667; Putative uncharacterized protein DKFZp434H0512
chr22_-_50913371 0.11 ENST00000348911.6
ENST00000380817.3
ENST00000390679.3
SBF1
SET binding factor 1
chr1_-_117210290 0.11 ENST00000369483.1
ENST00000369486.3
IGSF3
immunoglobulin superfamily, member 3
chr4_-_111544254 0.11 ENST00000306732.3
PITX2
paired-like homeodomain 2
chr14_+_23775971 0.10 ENST00000250405.5
BCL2L2
BCL2-like 2
chr6_-_82462425 0.10 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr18_-_55253989 0.10 ENST00000262093.5
FECH
ferrochelatase
chr7_-_44924939 0.10 ENST00000395699.2
PURB
purine-rich element binding protein B
chr5_+_138629417 0.10 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
MATR3
matrin 3
chr10_+_96162242 0.10 ENST00000225235.4
TBC1D12
TBC1 domain family, member 12
chr3_+_196594727 0.10 ENST00000445299.2
ENST00000323460.5
ENST00000419026.1
SENP5
SUMO1/sentrin specific peptidase 5
chr12_+_69004619 0.10 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B
RAP1B, member of RAS oncogene family
chr14_+_69726656 0.10 ENST00000337827.4
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr22_-_18507279 0.10 ENST00000441493.2
ENST00000444520.1
ENST00000207726.7
ENST00000429452.1
MICAL3
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr12_+_49372251 0.10 ENST00000293549.3
WNT1
wingless-type MMTV integration site family, member 1
chr16_+_30710462 0.10 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
SRCAP
Snf2-related CREBBP activator protein
chr22_-_22221900 0.10 ENST00000215832.6
ENST00000398822.3
MAPK1
mitogen-activated protein kinase 1
chr21_+_30671189 0.09 ENST00000286800.3
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr10_-_3827417 0.09 ENST00000497571.1
ENST00000542957.1
KLF6
Kruppel-like factor 6
chr2_+_208394616 0.09 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1
cAMP responsive element binding protein 1
chr3_-_50396978 0.09 ENST00000266025.3
TMEM115
transmembrane protein 115
chr1_-_207224307 0.09 ENST00000315927.4
YOD1
YOD1 deubiquitinase
chr4_-_152147579 0.09 ENST00000304527.4
ENST00000455740.1
ENST00000424281.1
ENST00000409598.4
SH3D19
SH3 domain containing 19
chr2_-_37193606 0.09 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr1_-_202858227 0.09 ENST00000367262.3
RABIF
RAB interacting factor
chr5_-_56247935 0.08 ENST00000381199.3
ENST00000381226.3
ENST00000381213.3
MIER3
mesoderm induction early response 1, family member 3
chr4_+_128703295 0.08 ENST00000296464.4
ENST00000508549.1
HSPA4L
heat shock 70kDa protein 4-like
chr1_-_19283163 0.08 ENST00000455833.2
IFFO2
intermediate filament family orphan 2
chr2_+_208576355 0.08 ENST00000420822.1
ENST00000295414.3
ENST00000339882.5
CCNYL1
cyclin Y-like 1
chr14_+_69865401 0.08 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
SLC39A9
solute carrier family 39, member 9
chr4_+_155665123 0.08 ENST00000336356.3
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr4_+_39046615 0.07 ENST00000261425.3
ENST00000508137.2
KLHL5
kelch-like family member 5
chr22_+_19118321 0.07 ENST00000399635.2
TSSK2
testis-specific serine kinase 2
chrX_-_83442915 0.07 ENST00000262752.2
ENST00000543399.1
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chrX_-_73834449 0.07 ENST00000332687.6
ENST00000349225.2
RLIM
ring finger protein, LIM domain interacting
chrX_-_70288234 0.07 ENST00000276105.3
ENST00000374274.3
SNX12
sorting nexin 12
chr15_-_83876758 0.07 ENST00000299633.4
HDGFRP3
Hepatoma-derived growth factor-related protein 3
chr1_+_10271674 0.07 ENST00000377086.1
KIF1B
kinesin family member 1B
chr17_-_4167142 0.07 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ANKFY1
ankyrin repeat and FYVE domain containing 1
chr1_-_173991434 0.06 ENST00000367696.2
RC3H1
ring finger and CCCH-type domains 1
chr9_+_132815985 0.06 ENST00000372410.3
GPR107
G protein-coupled receptor 107
chr4_+_184826418 0.06 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chr21_-_28338732 0.06 ENST00000284987.5
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr2_+_115199876 0.05 ENST00000436732.1
ENST00000410059.1
DPP10
dipeptidyl-peptidase 10 (non-functional)
chrX_+_37208521 0.05 ENST00000378628.4
PRRG1
proline rich Gla (G-carboxyglutamic acid) 1
chr7_+_39663061 0.05 ENST00000005257.2
RALA
v-ral simian leukemia viral oncogene homolog A (ras related)
chr4_+_55095264 0.05 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr18_+_9136758 0.05 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ANKRD12
ankyrin repeat domain 12
chr16_+_69221028 0.05 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr10_-_51623203 0.05 ENST00000444743.1
ENST00000374065.3
ENST00000374064.3
ENST00000260867.4
TIMM23
translocase of inner mitochondrial membrane 23 homolog (yeast)
chr19_-_2096259 0.05 ENST00000588048.1
ENST00000357066.3
MOB3A
MOB kinase activator 3A
chr1_+_25664408 0.05 ENST00000374358.4
TMEM50A
transmembrane protein 50A
chr19_+_39616410 0.05 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr16_-_66785699 0.05 ENST00000258198.2
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr15_+_81071684 0.05 ENST00000220244.3
ENST00000394685.3
ENST00000356249.5
KIAA1199
KIAA1199
chr7_-_75988321 0.04 ENST00000307630.3
YWHAG
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
chr7_-_117513540 0.04 ENST00000160373.3
CTTNBP2
cortactin binding protein 2
chr3_+_15468862 0.04 ENST00000396842.2
EAF1
ELL associated factor 1
chr7_+_128379346 0.04 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU
calumenin
chr11_+_46299199 0.04 ENST00000529193.1
ENST00000288400.3
CREB3L1
cAMP responsive element binding protein 3-like 1
chr9_-_99801592 0.04 ENST00000259470.5
CTSV
cathepsin V
chr5_+_14581884 0.04 ENST00000274217.3
FAM105A
family with sequence similarity 105, member A
chr9_-_107690420 0.04 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr11_-_46940074 0.04 ENST00000378623.1
ENST00000534404.1
LRP4
low density lipoprotein receptor-related protein 4
chr20_-_48770244 0.04 ENST00000371650.5
ENST00000371652.4
ENST00000557021.1
TMEM189
transmembrane protein 189
chr1_+_160313062 0.04 ENST00000294785.5
ENST00000368063.1
ENST00000437169.1
NCSTN
nicastrin
chr5_-_131347306 0.04 ENST00000296869.4
ENST00000379249.3
ENST00000379272.2
ENST00000379264.2
ACSL6
acyl-CoA synthetase long-chain family member 6
chr17_-_33416231 0.04 ENST00000584655.1
ENST00000447669.2
ENST00000315249.7
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr4_-_23891693 0.04 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr10_+_98592009 0.04 ENST00000540664.1
ENST00000371103.3
LCOR
ligand dependent nuclear receptor corepressor
chr12_-_7245125 0.03 ENST00000542285.1
ENST00000540610.1
C1R
complement component 1, r subcomponent
chr5_-_34916871 0.03 ENST00000382038.2
RAD1
RAD1 homolog (S. pombe)
chr7_-_112430647 0.03 ENST00000312814.6
TMEM168
transmembrane protein 168
chr20_+_19997948 0.03 ENST00000310450.4
ENST00000398602.2
NAA20
N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr11_-_31839488 0.03 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
PAX6
paired box 6
chr15_-_30114622 0.03 ENST00000495972.2
ENST00000346128.6
TJP1
tight junction protein 1
chr12_-_56652111 0.03 ENST00000267116.7
ANKRD52
ankyrin repeat domain 52
chr8_+_142402089 0.02 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3
protein tyrosine phosphatase type IVA, member 3
chr20_+_43991668 0.02 ENST00000243918.5
ENST00000426004.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr3_+_174577070 0.02 ENST00000454872.1
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr7_-_112727774 0.02 ENST00000297146.3
ENST00000501255.2
GPR85
G protein-coupled receptor 85
chr1_+_171810606 0.02 ENST00000358155.4
ENST00000367733.2
ENST00000355305.5
ENST00000367731.1
DNM3
dynamin 3
chr9_+_5629025 0.02 ENST00000251879.6
ENST00000414202.2
KIAA1432
KIAA1432
chr3_+_14444063 0.02 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr4_+_17616253 0.02 ENST00000237380.7
MED28
mediator complex subunit 28
chrX_+_37430822 0.02 ENST00000378621.3
ENST00000378619.3
LANCL3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr17_+_36508111 0.02 ENST00000331159.5
ENST00000577233.1
SOCS7
suppressor of cytokine signaling 7
chr18_+_32073253 0.02 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA
dystrobrevin, alpha
chr10_+_104535994 0.02 ENST00000369889.4
WBP1L
WW domain binding protein 1-like
chr20_+_32250079 0.02 ENST00000375222.3
C20orf144
chromosome 20 open reading frame 144
chr14_+_65171099 0.01 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr8_-_67579418 0.01 ENST00000310421.4
VCPIP1
valosin containing protein (p97)/p47 complex interacting protein 1
chr16_-_2264779 0.01 ENST00000333503.7
PGP
phosphoglycolate phosphatase
chr2_-_225450013 0.01 ENST00000264414.4
CUL3
cullin 3
chr12_+_2162447 0.01 ENST00000335762.5
ENST00000399655.1
CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr1_-_43424500 0.01 ENST00000415851.2
ENST00000426263.3
ENST00000372500.3
SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr7_+_91875508 0.01 ENST00000265742.3
ANKIB1
ankyrin repeat and IBR domain containing 1
chr1_+_100503643 0.01 ENST00000370152.3
HIAT1
hippocampus abundant transcript 1
chr14_-_74485960 0.01 ENST00000556242.1
ENST00000334696.6
ENTPD5
ectonucleoside triphosphate diphosphohydrolase 5
chr5_-_89825328 0.01 ENST00000500869.2
ENST00000315948.6
ENST00000509384.1
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr19_-_4066890 0.01 ENST00000322357.4
ZBTB7A
zinc finger and BTB domain containing 7A
chr2_-_37384175 0.00 ENST00000411537.2
ENST00000233057.4
ENST00000395127.2
ENST00000390013.3
EIF2AK2
eukaryotic translation initiation factor 2-alpha kinase 2
chr6_-_31628512 0.00 ENST00000375911.1
C6orf47
chromosome 6 open reading frame 47
chr15_+_90544532 0.00 ENST00000268154.4
ZNF710
zinc finger protein 710
chr20_+_49348081 0.00 ENST00000371610.2
PARD6B
par-6 family cell polarity regulator beta
chr18_-_24445729 0.00 ENST00000383168.4
AQP4
aquaporin 4
chr13_-_25746416 0.00 ENST00000515384.1
ENST00000357816.2
AMER2
APC membrane recruitment protein 2
chr5_+_126112794 0.00 ENST00000261366.5
ENST00000395354.1
LMNB1
lamin B1
chr20_-_46415297 0.00 ENST00000467815.1
ENST00000359930.4
SULF2
sulfatase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of AGUGGUU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.4 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.4 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.4 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.6 GO:0051414 response to cortisol(GO:0051414)
0.1 0.3 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.3 GO:1905075 proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.2 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.4 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087) mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 0.2 GO:0034238 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.1 0.2 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.1 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.2 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0061183 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.0 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.0 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.2 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.1 GO:0070541 response to platinum ion(GO:0070541)
0.0 0.3 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.2 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.0 0.2 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.3 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.0 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.0 0.3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.0 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.0 0.0 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.4 GO:0006907 pinocytosis(GO:0006907)
0.0 0.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.2 GO:0010225 response to UV-C(GO:0010225)
0.0 0.0 GO:1990834 response to odorant(GO:1990834)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.2 GO:0005606 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.0 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0097513 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.4 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.8 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0097363 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.9 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.0 GO:0030984 kininogen binding(GO:0030984)
0.0 0.0 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.0 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.2 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling