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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ALX1_ARX

Z-value: 0.33

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Transcription factors associated with ALX1_ARX

Gene Symbol Gene ID Gene Info
ALX1
ENSG00000180318.3 ALX homeobox 1
ARX
ENSG00000004848.6 aristaless related homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ALX1hg19_v2_chr12_+_85673868_85673885-0.154.8e-01Click!
ARXhg19_v2_chrX_-_25034065_25034088-0.009.8e-01Click!

Activity profile of ALX1_ARX motif

Sorted Z-values of ALX1_ARX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_95236551 0.47 ENST00000238558.3
GSC
goosecoid homeobox
chr17_+_39261584 0.45 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr6_-_134639180 0.44 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr2_+_162272605 0.37 ENST00000389554.3
TBR1
T-box, brain, 1
chr6_-_27835357 0.35 ENST00000331442.3
HIST1H1B
histone cluster 1, H1b
chrX_+_38211777 0.32 ENST00000039007.4
OTC
ornithine carbamoyltransferase
chr6_+_34204642 0.29 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr10_-_31146615 0.29 ENST00000444692.2
ZNF438
zinc finger protein 438
chr3_-_164914640 0.28 ENST00000241274.3
SLITRK3
SLIT and NTRK-like family, member 3
chr11_+_55029628 0.26 ENST00000417545.2
TRIM48
tripartite motif containing 48
chr2_+_152214098 0.25 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr18_+_616711 0.23 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chr2_-_145278475 0.22 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr12_-_43833515 0.22 ENST00000549670.1
ENST00000395541.2
ADAMTS20
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr18_+_616672 0.21 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr8_+_11961898 0.21 ENST00000400085.3
ZNF705D
zinc finger protein 705D
chr8_-_10512569 0.20 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr11_-_8964580 0.20 ENST00000325884.1
ASCL3
achaete-scute family bHLH transcription factor 3
chr12_-_118797475 0.20 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr2_+_196313239 0.19 ENST00000413290.1
AC064834.1
AC064834.1
chrX_-_11284095 0.16 ENST00000303025.6
ENST00000534860.1
ARHGAP6
Rho GTPase activating protein 6
chr4_-_100356291 0.16 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr3_-_196242233 0.16 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr6_+_12007963 0.15 ENST00000607445.1
RP11-456H18.2
RP11-456H18.2
chr5_-_160279207 0.15 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr3_-_12587055 0.15 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr17_+_3118915 0.15 ENST00000304094.1
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr3_+_130569429 0.14 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr6_+_12007897 0.14 ENST00000437559.1
RP11-456H18.2
RP11-456H18.2
chr3_-_191000172 0.14 ENST00000427544.2
UTS2B
urotensin 2B
chr17_-_60885700 0.14 ENST00000583600.1
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr2_+_102413726 0.14 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr17_-_60885659 0.14 ENST00000311269.5
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr1_+_50459990 0.13 ENST00000448346.1
AL645730.2
AL645730.2
chr17_-_39254391 0.13 ENST00000333822.4
KRTAP4-8
keratin associated protein 4-8
chr7_+_90339169 0.12 ENST00000436577.2
CDK14
cyclin-dependent kinase 14
chr11_-_96076334 0.12 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr11_-_40315640 0.12 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr10_-_50396425 0.12 ENST00000374148.1
C10orf128
chromosome 10 open reading frame 128
chr4_-_177116772 0.12 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr12_-_10151773 0.12 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr1_+_62439037 0.12 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr1_-_154600421 0.11 ENST00000368471.3
ENST00000292205.5
ADAR
adenosine deaminase, RNA-specific
chr1_-_151148442 0.11 ENST00000441701.1
ENST00000416280.2
TMOD4
tropomodulin 4 (muscle)
chr8_-_61880248 0.11 ENST00000525556.1
AC022182.3
AC022182.3
chr12_+_122688090 0.10 ENST00000324189.4
ENST00000546192.1
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chrX_-_19817869 0.10 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr4_-_87028478 0.10 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr12_+_14572070 0.09 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr2_+_119699864 0.09 ENST00000541757.1
ENST00000412481.1
MARCO
macrophage receptor with collagenous structure
chr17_+_39240459 0.09 ENST00000391417.4
KRTAP4-7
keratin associated protein 4-7
chr5_-_59783882 0.09 ENST00000505507.2
ENST00000502484.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_157824292 0.09 ENST00000483851.2
SHOX2
short stature homeobox 2
chr6_+_15401075 0.09 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr2_+_119699742 0.09 ENST00000327097.4
MARCO
macrophage receptor with collagenous structure
chr6_+_3259122 0.09 ENST00000438998.2
ENST00000380305.4
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr4_-_119759795 0.09 ENST00000419654.2
SEC24D
SEC24 family member D
chr4_+_69313145 0.09 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr18_-_19994830 0.09 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr9_+_124329336 0.09 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chrX_+_36254051 0.09 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr10_+_69865866 0.09 ENST00000354393.2
MYPN
myopalladin
chr1_-_151148492 0.08 ENST00000295314.4
TMOD4
tropomodulin 4 (muscle)
chr2_+_185463093 0.08 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr12_-_118628350 0.08 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr2_+_228678550 0.08 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr1_-_200379180 0.08 ENST00000294740.3
ZNF281
zinc finger protein 281
chr2_+_12246664 0.08 ENST00000449986.1
AC096559.1
AC096559.1
chr5_+_101569696 0.08 ENST00000597120.1
AC008948.1
AC008948.1
chr10_+_134150835 0.08 ENST00000432555.2
LRRC27
leucine rich repeat containing 27
chr5_+_145826867 0.08 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr2_+_36923830 0.08 ENST00000379242.3
ENST00000389975.3
VIT
vitrin
chr17_-_39296739 0.08 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr10_+_18689637 0.08 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr7_+_148287657 0.08 ENST00000307003.2
C7orf33
chromosome 7 open reading frame 33
chr4_+_48485341 0.07 ENST00000273861.4
SLC10A4
solute carrier family 10, member 4
chr13_-_47471155 0.07 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr4_+_88754113 0.07 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr4_-_143227088 0.07 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr8_-_122653630 0.07 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr1_+_104615595 0.07 ENST00000418362.1
RP11-364B6.1
RP11-364B6.1
chr7_+_90338712 0.07 ENST00000265741.3
ENST00000406263.1
CDK14
cyclin-dependent kinase 14
chr1_+_12976450 0.07 ENST00000361079.2
PRAMEF7
PRAME family member 7
chr3_-_47934234 0.07 ENST00000420772.2
MAP4
microtubule-associated protein 4
chr7_-_111032971 0.07 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr17_+_68071458 0.07 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr3_-_190167571 0.07 ENST00000354905.2
TMEM207
transmembrane protein 207
chr2_+_36923933 0.07 ENST00000497382.1
ENST00000404084.1
ENST00000379241.3
ENST00000401530.1
VIT
vitrin
chr8_+_77318769 0.07 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr6_+_45296391 0.07 ENST00000371436.6
ENST00000576263.1
RUNX2
runt-related transcription factor 2
chr17_+_68071389 0.06 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr15_+_51669444 0.06 ENST00000396399.2
GLDN
gliomedin
chrX_+_36246735 0.06 ENST00000378653.3
CXorf30
chromosome X open reading frame 30
chr5_+_59783941 0.06 ENST00000506884.1
ENST00000504876.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr12_-_53601055 0.06 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
ITGB7
integrin, beta 7
chr4_-_143226979 0.06 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr6_-_107235287 0.06 ENST00000436659.1
ENST00000428750.1
ENST00000427903.1
RP1-60O19.1
RP1-60O19.1
chr7_+_143701022 0.06 ENST00000408922.2
OR6B1
olfactory receptor, family 6, subfamily B, member 1
chr15_+_80733570 0.06 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr11_-_7847519 0.06 ENST00000328375.1
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chrX_+_149887090 0.06 ENST00000538506.1
MTMR1
myotubularin related protein 1
chr6_-_133055815 0.06 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr1_-_232651312 0.06 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr17_-_3030875 0.06 ENST00000328890.2
OR1G1
olfactory receptor, family 1, subfamily G, member 1
chr6_-_32908792 0.06 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr8_+_67039131 0.05 ENST00000315962.4
ENST00000353317.5
TRIM55
tripartite motif containing 55
chr8_-_57123815 0.05 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr14_-_38064198 0.05 ENST00000250448.2
FOXA1
forkhead box A1
chr1_+_206557366 0.05 ENST00000414007.1
ENST00000419187.2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr11_+_62496114 0.05 ENST00000532583.1
TTC9C
tetratricopeptide repeat domain 9C
chr5_-_87516448 0.05 ENST00000511218.1
TMEM161B
transmembrane protein 161B
chr11_+_18433840 0.05 ENST00000541669.1
ENST00000280704.4
LDHC
lactate dehydrogenase C
chr1_-_200379129 0.05 ENST00000367353.1
ZNF281
zinc finger protein 281
chr4_+_118955500 0.05 ENST00000296499.5
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr11_-_111649015 0.05 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr17_-_71228357 0.05 ENST00000583024.1
ENST00000403627.3
ENST00000405159.3
ENST00000581110.1
FAM104A
family with sequence similarity 104, member A
chr12_-_53601000 0.05 ENST00000338737.4
ENST00000549086.2
ITGB7
integrin, beta 7
chr5_+_40909354 0.05 ENST00000313164.9
C7
complement component 7
chr1_-_13390765 0.05 ENST00000357367.2
PRAMEF8
PRAME family member 8
chr7_-_25268104 0.05 ENST00000222674.2
NPVF
neuropeptide VF precursor
chr15_+_42066632 0.05 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr12_-_125052010 0.05 ENST00000458234.1
NCOR2
nuclear receptor corepressor 2
chr6_-_26199499 0.04 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr1_+_192127578 0.04 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr4_-_100356551 0.04 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr19_-_38183201 0.04 ENST00000590008.1
ENST00000358582.4
ZNF781
zinc finger protein 781
chr3_-_45837959 0.04 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr3_-_194188956 0.04 ENST00000256031.4
ENST00000446356.1
ATP13A3
ATPase type 13A3
chr3_-_87325728 0.04 ENST00000350375.2
POU1F1
POU class 1 homeobox 1
chr4_+_169013666 0.04 ENST00000359299.3
ANXA10
annexin A10
chr3_-_45838011 0.04 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr14_-_36988882 0.04 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr5_-_27038683 0.04 ENST00000511822.1
ENST00000231021.4
CDH9
cadherin 9, type 2 (T1-cadherin)
chr3_+_121774202 0.04 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr17_-_38911580 0.04 ENST00000312150.4
KRT25
keratin 25
chr6_+_26199737 0.04 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr2_+_74685413 0.04 ENST00000233615.2
WBP1
WW domain binding protein 1
chr11_-_92931098 0.04 ENST00000326402.4
SLC36A4
solute carrier family 36 (proton/amino acid symporter), member 4
chr1_+_186798073 0.04 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr5_-_115872142 0.04 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr2_-_55496174 0.04 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
MTIF2
mitochondrial translational initiation factor 2
chr16_+_1728257 0.04 ENST00000248098.3
ENST00000562684.1
ENST00000561516.1
ENST00000382711.5
ENST00000566742.1
HN1L
hematological and neurological expressed 1-like
chr6_-_66417107 0.04 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS
eyes shut homolog (Drosophila)
chr18_-_13915530 0.03 ENST00000327606.3
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr6_-_133055896 0.03 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr3_-_101039402 0.03 ENST00000193391.7
IMPG2
interphotoreceptor matrix proteoglycan 2
chr18_-_44181442 0.03 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr19_+_7030589 0.03 ENST00000329753.5
MBD3L5
methyl-CpG binding domain protein 3-like 5
chr12_-_112123524 0.03 ENST00000327551.6
BRAP
BRCA1 associated protein
chr4_+_155484155 0.03 ENST00000509493.1
FGB
fibrinogen beta chain
chr3_-_87325612 0.03 ENST00000561167.1
ENST00000560656.1
ENST00000344265.3
POU1F1
POU class 1 homeobox 1
chr4_+_88571429 0.03 ENST00000339673.6
ENST00000282479.7
DMP1
dentin matrix acidic phosphoprotein 1
chr2_+_58655461 0.03 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr5_+_140227357 0.03 ENST00000378122.3
PCDHA9
protocadherin alpha 9
chr4_+_74347400 0.03 ENST00000226355.3
AFM
afamin
chr6_+_31895254 0.03 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr3_-_3151664 0.03 ENST00000256452.3
ENST00000311981.8
ENST00000430514.2
ENST00000456302.1
IL5RA
interleukin 5 receptor, alpha
chr3_+_111393501 0.03 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr12_+_122241928 0.03 ENST00000604567.1
ENST00000542440.1
SETD1B
SET domain containing 1B
chr2_+_75873902 0.03 ENST00000393909.2
ENST00000358788.6
ENST00000409374.1
MRPL19
mitochondrial ribosomal protein L19
chr4_+_113568207 0.03 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr6_-_137314371 0.03 ENST00000432330.1
ENST00000418699.1
RP11-55K22.5
RP11-55K22.5
chr3_-_186262166 0.03 ENST00000307944.5
CRYGS
crystallin, gamma S
chr6_-_26199471 0.03 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chrX_+_107288197 0.03 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chrX_-_15332665 0.03 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr10_+_89420706 0.03 ENST00000427144.2
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chrX_-_15619076 0.02 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr4_-_83765613 0.02 ENST00000503937.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr3_+_155860751 0.02 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chrX_+_107288239 0.02 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chrX_+_16668278 0.02 ENST00000380200.3
S100G
S100 calcium binding protein G
chrX_+_119737806 0.02 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr3_-_32544900 0.02 ENST00000205636.3
CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr10_-_75226166 0.02 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr9_+_42671887 0.02 ENST00000456520.1
ENST00000377391.3
CBWD7
COBW domain containing 7
chr15_+_44092784 0.02 ENST00000458412.1
HYPK
huntingtin interacting protein K
chr4_+_54927213 0.02 ENST00000595906.1
AC110792.1
HCG2027126; Uncharacterized protein
chr9_+_77230499 0.02 ENST00000396204.2
RORB
RAR-related orphan receptor B
chr2_+_161993412 0.02 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr8_-_86253888 0.02 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
CA1
carbonic anhydrase I
chr6_-_150067696 0.02 ENST00000340413.2
ENST00000367403.3
NUP43
nucleoporin 43kDa
chr21_-_43346790 0.02 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chrX_-_48858667 0.02 ENST00000376423.4
ENST00000376441.1
GRIPAP1
GRIP1 associated protein 1
chr10_-_29923893 0.02 ENST00000355867.4
SVIL
supervillin
chr1_+_158323755 0.02 ENST00000368157.1
ENST00000368156.1
ENST00000368155.3
ENST00000368154.1
ENST00000368160.3
ENST00000368161.3
CD1E
CD1e molecule
chr5_+_137203465 0.02 ENST00000239926.4
MYOT
myotilin
chrX_-_48858630 0.02 ENST00000376425.3
ENST00000376444.3
GRIPAP1
GRIP1 associated protein 1
chr10_-_102989551 0.02 ENST00000370193.2
LBX1
ladybird homeobox 1
chr9_-_95298314 0.02 ENST00000344604.5
ENST00000375540.1
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr11_+_113779704 0.02 ENST00000537778.1
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
chr4_+_156824840 0.02 ENST00000536354.2
TDO2
tryptophan 2,3-dioxygenase
chr8_+_7353368 0.02 ENST00000355602.2
DEFB107B
defensin, beta 107B
chr11_-_124190184 0.02 ENST00000357438.2
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr9_+_44867571 0.02 ENST00000377548.2
RP11-160N1.10
RP11-160N1.10
chr14_-_81893734 0.02 ENST00000555447.1
STON2
stonin 2
chr4_-_89951028 0.01 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr4_-_176733897 0.01 ENST00000393658.2
GPM6A
glycoprotein M6A
chr4_+_95376396 0.01 ENST00000508216.1
ENST00000514743.1
PDLIM5
PDZ and LIM domain 5
chr19_+_7049332 0.01 ENST00000381393.3
MBD3L2
methyl-CpG binding domain protein 3-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ALX1_ARX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 0.3 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.1 0.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.4 GO:0021764 amygdala development(GO:0021764)
0.1 0.3 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.3 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.1 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.4 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.0 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation