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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ARID5B

Z-value: 0.62

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Transcription factors associated with ARID5B

Gene Symbol Gene ID Gene Info
ARID5B
ENSG00000150347.10 AT-rich interaction domain 5B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ARID5Bhg19_v2_chr10_+_63661053_636610790.414.0e-02Click!

Activity profile of ARID5B motif

Sorted Z-values of ARID5B motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_61330931 1.63 ENST00000371191.1
NFIA
nuclear factor I/A
chr12_+_79258547 1.52 ENST00000457153.2
SYT1
synaptotagmin I
chr12_+_79258444 1.45 ENST00000261205.4
SYT1
synaptotagmin I
chr5_-_88179302 1.26 ENST00000504921.2
MEF2C
myocyte enhancer factor 2C
chrX_+_86772787 1.13 ENST00000373114.4
KLHL4
kelch-like family member 4
chr1_-_76076793 1.10 ENST00000370859.3
SLC44A5
solute carrier family 44, member 5
chr3_+_43328004 1.01 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNRK
SNF related kinase
chr12_-_10007448 0.91 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr17_+_61086917 0.89 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr5_-_88179017 0.84 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
MEF2C
myocyte enhancer factor 2C
chr22_-_22090064 0.83 ENST00000339468.3
YPEL1
yippee-like 1 (Drosophila)
chr22_-_22090043 0.83 ENST00000403503.1
YPEL1
yippee-like 1 (Drosophila)
chr14_+_64680854 0.83 ENST00000458046.2
SYNE2
spectrin repeat containing, nuclear envelope 2
chr22_-_29107919 0.82 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr18_+_20513278 0.76 ENST00000327155.5
RBBP8
retinoblastoma binding protein 8
chr4_-_159094194 0.75 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr8_-_101322132 0.74 ENST00000523481.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr11_-_121986923 0.64 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr7_-_56119238 0.63 ENST00000275605.3
ENST00000395471.3
PSPH
phosphoserine phosphatase
chr1_+_6615241 0.61 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
TAS1R1
taste receptor, type 1, member 1
chr1_-_153066998 0.57 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr2_+_89999259 0.55 ENST00000558026.1
IGKV2D-28
immunoglobulin kappa variable 2D-28
chrX_+_102585124 0.55 ENST00000332431.4
ENST00000372666.1
TCEAL7
transcription elongation factor A (SII)-like 7
chr7_-_56119156 0.55 ENST00000421312.1
ENST00000416592.1
PSPH
phosphoserine phosphatase
chr22_+_19467261 0.54 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
CDC45
cell division cycle 45
chr19_+_57640011 0.53 ENST00000598197.1
USP29
ubiquitin specific peptidase 29
chr2_+_242498135 0.50 ENST00000318407.3
BOK
BCL2-related ovarian killer
chr19_-_3029011 0.49 ENST00000590536.1
ENST00000587137.1
ENST00000455444.2
ENST00000262953.6
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chrX_-_140786896 0.48 ENST00000370515.3
SPANXD
SPANX family, member D
chr9_-_116065551 0.47 ENST00000297894.5
RNF183
ring finger protein 183
chr9_+_116267536 0.46 ENST00000374136.1
RGS3
regulator of G-protein signaling 3
chr18_-_53303123 0.46 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr12_+_56324933 0.46 ENST00000549629.1
ENST00000555218.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr11_-_102714534 0.45 ENST00000299855.5
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr2_-_170430277 0.44 ENST00000438035.1
ENST00000453929.2
FASTKD1
FAST kinase domains 1
chr1_+_81771806 0.44 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr8_-_66474884 0.42 ENST00000520902.1
CTD-3025N20.2
CTD-3025N20.2
chr2_-_170430366 0.42 ENST00000453153.2
ENST00000445210.1
FASTKD1
FAST kinase domains 1
chr12_-_15038779 0.41 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chrX_-_57164058 0.41 ENST00000374906.3
SPIN2A
spindlin family, member 2A
chr1_-_76076759 0.41 ENST00000370855.5
SLC44A5
solute carrier family 44, member 5
chr12_+_56324756 0.40 ENST00000331886.5
ENST00000555090.1
DGKA
diacylglycerol kinase, alpha 80kDa
chrX_+_73164167 0.39 ENST00000414209.1
ENST00000602895.1
ENST00000453317.1
ENST00000602546.1
ENST00000602985.1
ENST00000415215.1
JPX
JPX transcript, XIST activator (non-protein coding)
chr6_+_132891461 0.36 ENST00000275198.1
TAAR6
trace amine associated receptor 6
chr12_-_57146095 0.36 ENST00000550770.1
ENST00000338193.6
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr3_-_151102529 0.35 ENST00000302632.3
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr5_+_175288631 0.35 ENST00000509837.1
CPLX2
complexin 2
chr11_-_33774944 0.35 ENST00000532057.1
ENST00000531080.1
FBXO3
F-box protein 3
chr12_-_122879969 0.34 ENST00000540304.1
CLIP1
CAP-GLY domain containing linker protein 1
chr1_+_158975744 0.34 ENST00000426592.2
IFI16
interferon, gamma-inducible protein 16
chr15_+_25068773 0.32 ENST00000400100.1
ENST00000400098.1
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr9_-_21202204 0.32 ENST00000239347.3
IFNA7
interferon, alpha 7
chr1_-_149459549 0.31 ENST00000369175.3
FAM72C
family with sequence similarity 72, member C
chr3_+_183770835 0.30 ENST00000318351.1
HTR3C
5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
chr4_+_71588372 0.30 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr7_+_116660246 0.29 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chr5_+_92919043 0.28 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr4_+_147096837 0.28 ENST00000296581.5
ENST00000502781.1
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_+_186798073 0.28 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr1_-_40137710 0.28 ENST00000235628.1
NT5C1A
5'-nucleotidase, cytosolic IA
chr12_+_51236703 0.27 ENST00000551456.1
ENST00000398458.3
TMPRSS12
transmembrane (C-terminal) protease, serine 12
chr5_+_135496675 0.27 ENST00000507637.1
SMAD5
SMAD family member 5
chr1_+_150039369 0.26 ENST00000369130.3
ENST00000369128.5
VPS45
vacuolar protein sorting 45 homolog (S. cerevisiae)
chrX_-_33229636 0.26 ENST00000357033.4
DMD
dystrophin
chr12_+_56390964 0.25 ENST00000356124.4
ENST00000266971.3
ENST00000394115.2
ENST00000547586.1
ENST00000552258.1
ENST00000548274.1
ENST00000546833.1
SUOX
sulfite oxidase
chr17_-_36358166 0.25 ENST00000537432.1
TBC1D3
TBC1 domain family, member 3
chr17_+_3379284 0.25 ENST00000263080.2
ASPA
aspartoacylase
chr14_-_105708942 0.24 ENST00000549655.1
BRF1
BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
chr3_-_15540055 0.23 ENST00000605797.1
ENST00000435459.2
COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr5_+_154393260 0.22 ENST00000435029.4
KIF4B
kinesin family member 4B
chr3_-_98241760 0.21 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
CLDND1
claudin domain containing 1
chr3_-_98241358 0.20 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr11_-_104769141 0.20 ENST00000508062.1
ENST00000422698.2
CASP12
caspase 12 (gene/pseudogene)
chr22_+_40573921 0.20 ENST00000454349.2
ENST00000335727.9
TNRC6B
trinucleotide repeat containing 6B
chr11_+_101983176 0.19 ENST00000524575.1
YAP1
Yes-associated protein 1
chr1_-_168106536 0.19 ENST00000537209.1
ENST00000361697.2
ENST00000546300.1
ENST00000367835.1
GPR161
G protein-coupled receptor 161
chr15_+_80364901 0.19 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
ZFAND6
zinc finger, AN1-type domain 6
chr9_-_32552551 0.19 ENST00000360538.2
ENST00000379858.1
TOPORS
topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
chr20_+_11008811 0.19 ENST00000537362.1
C20orf187
chromosome 20 open reading frame 187
chr1_+_32608566 0.19 ENST00000545542.1
KPNA6
karyopherin alpha 6 (importin alpha 7)
chr2_+_181845843 0.18 ENST00000602710.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr9_+_42671887 0.18 ENST00000456520.1
ENST00000377391.3
CBWD7
COBW domain containing 7
chr12_+_120933904 0.17 ENST00000550178.1
ENST00000550845.1
ENST00000549989.1
ENST00000552870.1
DYNLL1
dynein, light chain, LC8-type 1
chr1_+_152975488 0.17 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr9_+_77230499 0.17 ENST00000396204.2
RORB
RAR-related orphan receptor B
chr12_-_68553512 0.17 ENST00000229135.3
IFNG
interferon, gamma
chr4_+_76871883 0.17 ENST00000599764.1
AC110615.1
Uncharacterized protein
chrX_-_130037198 0.17 ENST00000370935.1
ENST00000338144.3
ENST00000394363.1
ENOX2
ecto-NOX disulfide-thiol exchanger 2
chr11_-_111794446 0.17 ENST00000527950.1
CRYAB
crystallin, alpha B
chr2_-_242556900 0.17 ENST00000402545.1
ENST00000402136.1
THAP4
THAP domain containing 4
chr11_+_30253410 0.16 ENST00000533718.1
FSHB
follicle stimulating hormone, beta polypeptide
chr6_+_122720681 0.16 ENST00000368455.4
ENST00000452194.1
HSF2
heat shock transcription factor 2
chr3_+_32726620 0.16 ENST00000331889.6
ENST00000328834.5
CNOT10
CCR4-NOT transcription complex, subunit 10
chr6_+_24775153 0.16 ENST00000356509.3
ENST00000230056.3
GMNN
geminin, DNA replication inhibitor
chr12_+_120933859 0.15 ENST00000242577.6
ENST00000548214.1
ENST00000392508.2
DYNLL1
dynein, light chain, LC8-type 1
chr13_+_53216565 0.15 ENST00000357495.2
HNRNPA1L2
heterogeneous nuclear ribonucleoprotein A1-like 2
chr6_-_30080863 0.15 ENST00000540829.1
TRIM31
tripartite motif containing 31
chr6_+_42896865 0.15 ENST00000372836.4
ENST00000394142.3
CNPY3
canopy FGF signaling regulator 3
chr12_-_91539918 0.15 ENST00000548218.1
DCN
decorin
chr4_-_89978299 0.15 ENST00000511976.1
ENST00000509094.1
ENST00000264344.5
ENST00000515600.1
FAM13A
family with sequence similarity 13, member A
chrX_-_101410762 0.15 ENST00000543160.1
ENST00000333643.3
BEX5
brain expressed, X-linked 5
chr3_-_114790179 0.15 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr10_-_69835099 0.14 ENST00000373700.4
HERC4
HECT and RLD domain containing E3 ubiquitin protein ligase 4
chr12_-_56321397 0.14 ENST00000557259.1
ENST00000549939.1
WIBG
within bgcn homolog (Drosophila)
chr7_-_37488834 0.13 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr3_-_185538849 0.13 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr10_-_69834973 0.13 ENST00000395187.2
HERC4
HECT and RLD domain containing E3 ubiquitin protein ligase 4
chr9_+_706842 0.13 ENST00000382293.3
KANK1
KN motif and ankyrin repeat domains 1
chr18_-_51107372 0.12 ENST00000565170.1
RP11-202D1.2
RP11-202D1.2
chr1_+_47264711 0.11 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
CYP4B1
cytochrome P450, family 4, subfamily B, polypeptide 1
chr1_+_150266256 0.11 ENST00000309092.7
ENST00000369084.5
MRPS21
mitochondrial ribosomal protein S21
chr5_+_137225125 0.11 ENST00000350250.4
ENST00000508638.1
ENST00000502810.1
ENST00000508883.1
PKD2L2
polycystic kidney disease 2-like 2
chr9_+_35806082 0.11 ENST00000447210.1
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr11_-_78052923 0.11 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr1_-_160231451 0.11 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr21_+_30502806 0.11 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr5_+_68462837 0.11 ENST00000256442.5
CCNB1
cyclin B1
chr10_+_126150369 0.11 ENST00000392757.4
ENST00000368842.5
ENST00000368839.1
LHPP
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr5_+_173763250 0.10 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1
RP11-267A15.1
chr3_-_52713729 0.10 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
PBRM1
polybromo 1
chr10_+_120116527 0.10 ENST00000445161.1
LINC00867
long intergenic non-protein coding RNA 867
chr17_-_3599696 0.10 ENST00000225328.5
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr17_-_3599492 0.10 ENST00000435558.1
ENST00000345901.3
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr10_+_4828815 0.09 ENST00000533295.1
AKR1E2
aldo-keto reductase family 1, member E2
chr1_-_153085984 0.09 ENST00000468739.1
SPRR2F
small proline-rich protein 2F
chr7_-_24797546 0.09 ENST00000414428.1
ENST00000419307.1
ENST00000342947.3
DFNA5
deafness, autosomal dominant 5
chr12_-_10962767 0.09 ENST00000240691.2
TAS2R9
taste receptor, type 2, member 9
chr14_+_96968707 0.08 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
PAPOLA
poly(A) polymerase alpha
chr4_+_95376396 0.08 ENST00000508216.1
ENST00000514743.1
PDLIM5
PDZ and LIM domain 5
chr10_-_69835001 0.08 ENST00000513996.1
ENST00000412272.2
ENST00000395198.3
ENST00000492996.2
HERC4
HECT and RLD domain containing E3 ubiquitin protein ligase 4
chr6_-_137494775 0.08 ENST00000349184.4
ENST00000296980.2
ENST00000339602.3
IL22RA2
interleukin 22 receptor, alpha 2
chr7_-_104909435 0.08 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr2_-_114300213 0.08 ENST00000446595.1
ENST00000416105.1
ENST00000450636.1
ENST00000416758.1
RP11-395L14.4
RP11-395L14.4
chr1_+_151739131 0.07 ENST00000400999.1
OAZ3
ornithine decarboxylase antizyme 3
chr8_+_94752349 0.07 ENST00000391680.1
RBM12B-AS1
RBM12B antisense RNA 1
chr6_-_160210715 0.07 ENST00000392168.2
ENST00000321394.7
TCP1
t-complex 1
chr2_+_119699864 0.06 ENST00000541757.1
ENST00000412481.1
MARCO
macrophage receptor with collagenous structure
chr2_-_89327228 0.06 ENST00000483158.1
IGKV3-11
immunoglobulin kappa variable 3-11
chr5_-_64920115 0.06 ENST00000381018.3
ENST00000274327.7
TRIM23
tripartite motif containing 23
chr12_+_128399917 0.06 ENST00000544645.1
LINC00507
long intergenic non-protein coding RNA 507
chr4_+_187187337 0.06 ENST00000492972.2
F11
coagulation factor XI
chr12_-_91573249 0.06 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr1_-_144995074 0.06 ENST00000534536.1
PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_85742773 0.05 ENST00000370580.1
BCL10
B-cell CLL/lymphoma 10
chr7_+_116654935 0.05 ENST00000432298.1
ENST00000422922.1
ST7
suppression of tumorigenicity 7
chr14_-_69263043 0.05 ENST00000408913.2
ZFP36L1
ZFP36 ring finger protein-like 1
chr3_-_98241713 0.05 ENST00000502288.1
ENST00000512147.1
ENST00000510541.1
ENST00000503621.1
ENST00000511081.1
CLDND1
claudin domain containing 1
chr8_-_101321584 0.05 ENST00000523167.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr11_-_110460409 0.04 ENST00000529591.1
ARHGAP20
Rho GTPase activating protein 20
chr12_+_128399965 0.04 ENST00000540882.1
ENST00000542089.1
LINC00507
long intergenic non-protein coding RNA 507
chrX_+_140677562 0.04 ENST00000370518.3
SPANXA2
SPANX family, member A2
chr4_-_90229142 0.04 ENST00000609438.1
GPRIN3
GPRIN family member 3
chr3_-_113897899 0.04 ENST00000383673.2
ENST00000295881.7
DRD3
dopamine receptor D3
chr1_-_157014865 0.03 ENST00000361409.2
ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11
chr1_+_228870824 0.03 ENST00000366691.3
RHOU
ras homolog family member U
chr18_-_25616519 0.03 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr10_-_128210005 0.03 ENST00000284694.7
ENST00000454341.1
ENST00000432642.1
ENST00000392694.1
C10orf90
chromosome 10 open reading frame 90
chr12_-_67197760 0.03 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr1_-_31538517 0.03 ENST00000440538.2
ENST00000423018.2
ENST00000424085.2
ENST00000426105.2
ENST00000257075.5
ENST00000373747.3
ENST00000525843.1
ENST00000373742.2
PUM1
pumilio RNA-binding family member 1
chr2_+_133874577 0.02 ENST00000596384.1
AC011755.1
HCG2006742; Protein LOC100996685
chr6_+_126661253 0.02 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
CENPW
centromere protein W
chr1_+_21877753 0.02 ENST00000374832.1
ALPL
alkaline phosphatase, liver/bone/kidney
chr20_-_9819674 0.02 ENST00000378429.3
PAK7
p21 protein (Cdc42/Rac)-activated kinase 7
chr6_-_30080876 0.02 ENST00000376734.3
TRIM31
tripartite motif containing 31
chrX_+_54466829 0.02 ENST00000375151.4
TSR2
TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
chr9_+_125796806 0.02 ENST00000373642.1
GPR21
G protein-coupled receptor 21
chr3_-_139396853 0.01 ENST00000406164.1
ENST00000406824.1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr17_+_37356555 0.01 ENST00000579374.1
RPL19
ribosomal protein L19
chr1_-_115292591 0.01 ENST00000438362.2
CSDE1
cold shock domain containing E1, RNA-binding
chr4_+_187187098 0.01 ENST00000403665.2
ENST00000264692.4
F11
coagulation factor XI
chr3_+_184018352 0.01 ENST00000435761.1
ENST00000439383.1
PSMD2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr3_+_32726774 0.01 ENST00000538368.1
CNOT10
CCR4-NOT transcription complex, subunit 10
chr5_+_446253 0.01 ENST00000315013.5
EXOC3
exocyst complex component 3
chr17_+_37356586 0.01 ENST00000579260.1
ENST00000582193.1
RPL19
ribosomal protein L19
chr17_+_37356528 0.01 ENST00000225430.4
RPL19
ribosomal protein L19
chr3_-_113897545 0.00 ENST00000467632.1
DRD3
dopamine receptor D3
chr22_-_42086477 0.00 ENST00000402458.1
NHP2L1
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
chr1_+_92632542 0.00 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chr11_+_46193466 0.00 ENST00000533793.1
RP11-702F3.3
RP11-702F3.3
chr4_-_57524061 0.00 ENST00000508121.1
HOPX
HOP homeobox

Network of associatons between targets according to the STRING database.

First level regulatory network of ARID5B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.5 2.1 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.3 0.8 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 0.5 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.8 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.5 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1 0.6 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.8 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 1.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 1.5 GO:0015871 choline transport(GO:0015871)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.3 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.3 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.2 GO:0032829 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309)
0.1 1.5 GO:0072189 ureter development(GO:0072189)
0.1 0.4 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.2 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.5 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.3 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.3 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.2 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.1 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.0 0.9 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0009304 tRNA transcription(GO:0009304)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.2 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0032765 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) positive regulation of mast cell cytokine production(GO:0032765)
0.0 0.1 GO:1904582 mesendoderm development(GO:0048382) regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.0 0.1 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.4 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 1.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.3 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.0 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 0.5 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.4 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0046696 CBM complex(GO:0032449) lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 1.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 1.5 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.4 GO:0003896 DNA primase activity(GO:0003896)
0.1 2.1 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.2 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.1 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.3 GO:0030151 molybdenum ion binding(GO:0030151)
0.1 0.8 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.7 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 2.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.6 PID ATM PATHWAY ATM pathway
0.0 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 2.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling