Project
Inflammatory response time course, HUVEC (Wada et al., 2009)
Navigation
Downloads
Results for ATF5
Z-value: 0.57
Motif logo
Transcription factors associated with ATF5
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ATF5 | hg19_v2_chr19_+_50431959_50431998 | 0.40 | 4.7e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_+_4229495 Show fit | 3.11 |
ENST00000221847.5
|
Epstein-Barr virus induced 3 |
|
| chr3_-_127441406 Show fit | 1.87 |
ENST00000487473.1
ENST00000484451.1 |
monoglyceride lipase |
|
| chr16_-_65155979 Show fit | 1.84 |
ENST00000562325.1
ENST00000268603.4 |
cadherin 11, type 2, OB-cadherin (osteoblast) |
|
| chr16_-_65155833 Show fit | 1.75 |
ENST00000566827.1
ENST00000394156.3 ENST00000562998.1 |
cadherin 11, type 2, OB-cadherin (osteoblast) |
|
| chr9_+_116917807 Show fit | 1.58 |
ENST00000356083.3
|
collagen, type XXVII, alpha 1 |
|
| chr7_-_115670792 Show fit | 1.54 |
ENST00000265440.7
ENST00000393485.1 |
transcription factor EC |
|
| chr7_-_115670804 Show fit | 1.47 |
ENST00000320239.7
|
transcription factor EC |
|
| chr2_-_113542063 Show fit | 1.42 |
ENST00000263339.3
|
interleukin 1, alpha |
|
| chr7_-_41740181 Show fit | 1.41 |
ENST00000442711.1
|
inhibin, beta A |
|
| chr4_-_122085469 Show fit | 1.09 |
ENST00000057513.3
|
TNFAIP3 interacting protein 3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ATF5
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.1 | GO:0021957 | corticospinal tract morphogenesis(GO:0021957) |
| 0.2 | 3.1 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.0 | 3.0 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.3 | 1.9 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.2 | 1.6 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
| 0.2 | 1.5 | GO:0061088 | regulation of sequestering of zinc ion(GO:0061088) |
| 0.5 | 1.4 | GO:0060278 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 0.2 | 1.4 | GO:0034436 | glycoprotein transport(GO:0034436) |
| 0.2 | 1.4 | GO:2000391 | positive regulation of neutrophil extravasation(GO:2000391) |
| 0.0 | 1.4 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.4 | GO:0043511 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.0 | 1.4 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.0 | 1.4 | GO:0034385 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.1 | 1.1 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.3 | 1.0 | GO:0044609 | DBIRD complex(GO:0044609) |
| 0.0 | 1.0 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 0.9 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.2 | 0.6 | GO:0042585 | germinal vesicle(GO:0042585) |
| 0.0 | 0.6 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.1 | 0.5 | GO:0031085 | BLOC-3 complex(GO:0031085) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.1 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.1 | 1.9 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 1.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.5 | 1.4 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) |
| 0.5 | 1.4 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.1 | 1.4 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 1.3 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 1.1 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.0 | 1.1 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 1.0 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.6 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.0 | 1.7 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 1.4 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 1.4 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 1.4 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 1.1 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.0 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.0 | 1.0 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 0.9 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 0.9 | PID MYC PATHWAY | C-MYC pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.3 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 2.4 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 1.5 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.1 | 1.4 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.0 | 1.4 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.0 | 1.1 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 0.9 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 0.8 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 0.6 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.0 | 0.6 | REACTOME OPSINS | Genes involved in Opsins |