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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ATF5

Z-value: 0.57

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Transcription factors associated with ATF5

Gene Symbol Gene ID Gene Info
ATF5
ENSG00000169136.4 activating transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF5hg19_v2_chr19_+_50431959_504319980.404.7e-02Click!

Activity profile of ATF5 motif

Sorted Z-values of ATF5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_4229495 3.11 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr3_-_127441406 1.87 ENST00000487473.1
ENST00000484451.1
MGLL
monoglyceride lipase
chr16_-_65155979 1.84 ENST00000562325.1
ENST00000268603.4
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr16_-_65155833 1.75 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr9_+_116917807 1.58 ENST00000356083.3
COL27A1
collagen, type XXVII, alpha 1
chr7_-_115670792 1.54 ENST00000265440.7
ENST00000393485.1
TFEC
transcription factor EC
chr7_-_115670804 1.47 ENST00000320239.7
TFEC
transcription factor EC
chr2_-_113542063 1.42 ENST00000263339.3
IL1A
interleukin 1, alpha
chr7_-_41740181 1.41 ENST00000442711.1
INHBA
inhibin, beta A
chr4_-_122085469 1.09 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr1_+_101361782 0.95 ENST00000357650.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr9_+_109625378 0.90 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
ZNF462
zinc finger protein 462
chr6_+_43738444 0.87 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA
vascular endothelial growth factor A
chr2_-_100759037 0.83 ENST00000317233.4
ENST00000423966.1
ENST00000416492.1
AFF3
AF4/FMR2 family, member 3
chr10_+_111765562 0.78 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr19_-_10491234 0.75 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
TYK2
tyrosine kinase 2
chr16_-_72127456 0.73 ENST00000562153.1
TXNL4B
thioredoxin-like 4B
chr9_+_2622085 0.72 ENST00000382099.2
VLDLR
very low density lipoprotein receptor
chr9_+_2621798 0.71 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chr12_-_16761007 0.69 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr5_-_20575959 0.68 ENST00000507958.1
CDH18
cadherin 18, type 2
chr12_+_32655110 0.65 ENST00000546442.1
ENST00000583694.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr20_+_58179582 0.65 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr14_+_23846328 0.64 ENST00000382809.2
CMTM5
CKLF-like MARVEL transmembrane domain containing 5
chr14_+_32546274 0.64 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr6_+_114178512 0.64 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr11_-_126870655 0.60 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr1_+_101361626 0.56 ENST00000370112.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr8_+_22462532 0.51 ENST00000389279.3
CCAR2
cell cycle and apoptosis regulator 2
chr2_-_145278475 0.49 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr8_+_22462145 0.47 ENST00000308511.4
ENST00000523801.1
ENST00000521301.1
CCAR2
cell cycle and apoptosis regulator 2
chr10_-_99531709 0.46 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chr4_+_77172847 0.44 ENST00000515604.1
ENST00000539752.1
ENST00000424749.2
FAM47E
FAM47E-STBD1
FAM47E
uncharacterized protein LOC100631383
FAM47E-STBD1 readthrough
family with sequence similarity 47, member E
chr1_+_209859510 0.43 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr16_-_72128270 0.41 ENST00000426362.2
TXNL4B
thioredoxin-like 4B
chr2_-_87017985 0.41 ENST00000352580.3
CD8A
CD8a molecule
chr16_-_30023615 0.38 ENST00000564979.1
ENST00000563378.1
DOC2A
double C2-like domains, alpha
chr6_+_44095347 0.37 ENST00000323267.6
TMEM63B
transmembrane protein 63B
chr20_+_62492566 0.37 ENST00000369916.3
ABHD16B
abhydrolase domain containing 16B
chr11_+_124735282 0.35 ENST00000397801.1
ROBO3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr15_+_63481668 0.35 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B
RAB8B, member RAS oncogene family
chr7_-_3083573 0.34 ENST00000396946.4
CARD11
caspase recruitment domain family, member 11
chr5_+_34757309 0.34 ENST00000397449.1
RAI14
retinoic acid induced 14
chr9_-_38069208 0.34 ENST00000377707.3
ENST00000377700.4
SHB
Src homology 2 domain containing adaptor protein B
chr17_-_47287928 0.33 ENST00000507680.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr4_+_159443090 0.33 ENST00000343542.5
ENST00000470033.1
RXFP1
relaxin/insulin-like family peptide receptor 1
chr3_-_8686479 0.33 ENST00000544814.1
ENST00000427408.1
SSUH2
ssu-2 homolog (C. elegans)
chrX_+_122318113 0.33 ENST00000371264.3
GRIA3
glutamate receptor, ionotropic, AMPA 3
chr14_-_65569186 0.32 ENST00000555932.1
ENST00000358664.4
ENST00000284165.6
ENST00000358402.4
ENST00000246163.2
ENST00000556979.1
ENST00000555667.1
ENST00000557746.1
ENST00000556443.1
MAX
MYC associated factor X
chrX_+_103810874 0.32 ENST00000372582.1
IL1RAPL2
interleukin 1 receptor accessory protein-like 2
chr12_-_49351303 0.31 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chrX_+_153409678 0.31 ENST00000369951.4
OPN1LW
opsin 1 (cone pigments), long-wave-sensitive
chr1_-_183387723 0.30 ENST00000287713.6
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr6_-_62996066 0.30 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr6_-_88411911 0.30 ENST00000257787.5
AKIRIN2
akirin 2
chr2_-_87018784 0.29 ENST00000283635.3
ENST00000538832.1
CD8A
CD8a molecule
chr14_-_65569057 0.29 ENST00000555419.1
ENST00000341653.2
MAX
MYC associated factor X
chr19_+_15160130 0.29 ENST00000427043.3
CASP14
caspase 14, apoptosis-related cysteine peptidase
chr16_-_72127550 0.28 ENST00000268483.3
TXNL4B
thioredoxin-like 4B
chr14_+_23846210 0.28 ENST00000339180.4
ENST00000342473.4
ENST00000397227.3
ENST00000555731.1
CMTM5
CKLF-like MARVEL transmembrane domain containing 5
chr8_-_21645804 0.28 ENST00000518077.1
ENST00000517892.1
GFRA2
GDNF family receptor alpha 2
chr17_+_33914276 0.27 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr5_+_50678921 0.27 ENST00000230658.7
ISL1
ISL LIM homeobox 1
chr3_+_38206975 0.27 ENST00000446845.1
ENST00000311806.3
OXSR1
oxidative stress responsive 1
chr14_-_65569244 0.27 ENST00000557277.1
ENST00000556892.1
MAX
MYC associated factor X
chr15_-_90222610 0.26 ENST00000300055.5
PLIN1
perilipin 1
chr15_-_90222642 0.26 ENST00000430628.2
PLIN1
perilipin 1
chr22_-_36236265 0.26 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr5_+_137203465 0.26 ENST00000239926.4
MYOT
myotilin
chr17_+_33914460 0.26 ENST00000537622.2
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chrX_+_153448107 0.25 ENST00000369935.5
OPN1MW
opsin 1 (cone pigments), medium-wave-sensitive
chr18_-_3845293 0.25 ENST00000400145.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr4_+_159443024 0.25 ENST00000448688.2
RXFP1
relaxin/insulin-like family peptide receptor 1
chr14_+_23845995 0.24 ENST00000359320.3
CMTM5
CKLF-like MARVEL transmembrane domain containing 5
chr20_+_43211149 0.24 ENST00000372886.1
PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr18_-_19748331 0.24 ENST00000584201.1
GATA6-AS1
GATA6 antisense RNA 1 (head to head)
chr15_-_88799948 0.24 ENST00000394480.2
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr8_-_95449155 0.24 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr22_-_26875345 0.24 ENST00000398141.1
HPS4
Hermansky-Pudlak syndrome 4
chr14_-_21566731 0.23 ENST00000360947.3
ZNF219
zinc finger protein 219
chr22_-_26875631 0.23 ENST00000402105.3
HPS4
Hermansky-Pudlak syndrome 4
chr5_+_110559603 0.23 ENST00000512453.1
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr1_-_27930102 0.23 ENST00000247087.5
ENST00000374011.2
AHDC1
AT hook, DNA binding motif, containing 1
chr14_-_36988882 0.22 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr18_-_3845321 0.22 ENST00000539435.1
ENST00000400147.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr3_+_112930387 0.21 ENST00000485230.1
BOC
BOC cell adhesion associated, oncogene regulated
chr18_-_19748379 0.21 ENST00000579431.1
GATA6-AS1
GATA6 antisense RNA 1 (head to head)
chr9_-_23825956 0.21 ENST00000397312.2
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr5_+_82767487 0.21 ENST00000343200.5
ENST00000342785.4
VCAN
versican
chr14_+_79745746 0.21 ENST00000281127.7
NRXN3
neurexin 3
chr16_+_30075463 0.21 ENST00000562168.1
ENST00000569545.1
ALDOA
aldolase A, fructose-bisphosphate
chr8_-_13134045 0.20 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr12_-_100656134 0.20 ENST00000548313.1
DEPDC4
DEP domain containing 4
chrX_+_131157609 0.20 ENST00000496850.1
MST4
Serine/threonine-protein kinase MST4
chr12_-_120884175 0.20 ENST00000546954.1
TRIAP1
TP53 regulated inhibitor of apoptosis 1
chr15_-_75871589 0.19 ENST00000306726.2
PTPN9
protein tyrosine phosphatase, non-receptor type 9
chr5_+_156887027 0.19 ENST00000435489.2
ENST00000311946.7
NIPAL4
NIPA-like domain containing 4
chr7_-_27142290 0.19 ENST00000222718.5
HOXA2
homeobox A2
chr16_-_58663720 0.19 ENST00000564557.1
ENST00000569240.1
ENST00000441024.2
ENST00000569020.1
ENST00000317147.5
CNOT1
CCR4-NOT transcription complex, subunit 1
chrX_+_47050236 0.18 ENST00000377351.4
UBA1
ubiquitin-like modifier activating enzyme 1
chr17_-_73149921 0.17 ENST00000481647.1
ENST00000470924.1
HN1
hematological and neurological expressed 1
chr5_+_82767583 0.17 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN
versican
chr7_-_155604967 0.17 ENST00000297261.2
SHH
sonic hedgehog
chr14_+_79746249 0.17 ENST00000428277.2
NRXN3
neurexin 3
chr3_-_182698381 0.17 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chrX_+_133930798 0.17 ENST00000414371.2
FAM122C
family with sequence similarity 122C
chr1_-_151804222 0.17 ENST00000392697.3
RORC
RAR-related orphan receptor C
chr4_-_159956333 0.17 ENST00000434826.2
C4orf45
chromosome 4 open reading frame 45
chr4_-_175750364 0.16 ENST00000340217.5
ENST00000274093.3
GLRA3
glycine receptor, alpha 3
chr2_-_214016314 0.16 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr8_+_79428539 0.16 ENST00000352966.5
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chrX_-_47489244 0.16 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
CFP
complement factor properdin
chr6_+_87865262 0.16 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr8_-_61193947 0.16 ENST00000317995.4
CA8
carbonic anhydrase VIII
chr9_+_103947311 0.15 ENST00000395056.2
LPPR1
Lipid phosphate phosphatase-related protein type 1
chr14_+_32546145 0.15 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr11_+_62495997 0.15 ENST00000316461.4
TTC9C
tetratricopeptide repeat domain 9C
chr5_+_154393260 0.14 ENST00000435029.4
KIF4B
kinesin family member 4B
chr11_-_132813566 0.14 ENST00000331898.7
OPCML
opioid binding protein/cell adhesion molecule-like
chr8_-_623547 0.14 ENST00000522893.1
ERICH1
glutamate-rich 1
chr5_-_134788086 0.14 ENST00000537858.1
TIFAB
TRAF-interacting protein with forkhead-associated domain, family member B
chr6_+_72596604 0.14 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1
regulating synaptic membrane exocytosis 1
chr13_+_28366780 0.14 ENST00000302945.2
GSX1
GS homeobox 1
chr12_+_120884222 0.13 ENST00000551765.1
ENST00000229384.5
GATC
glutamyl-tRNA(Gln) amidotransferase, subunit C
chr19_-_7936344 0.13 ENST00000599142.1
CTD-3193O13.9
Protein FLJ22184
chr11_-_108408895 0.13 ENST00000443411.1
ENST00000533052.1
EXPH5
exophilin 5
chr1_-_27286897 0.13 ENST00000320567.5
C1orf172
chromosome 1 open reading frame 172
chr1_+_48688357 0.13 ENST00000533824.1
ENST00000438567.2
ENST00000236495.5
ENST00000420136.2
SLC5A9
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr15_+_80733570 0.13 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr1_+_206579736 0.13 ENST00000439126.1
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr16_+_22103828 0.13 ENST00000567131.1
ENST00000568328.1
ENST00000389398.5
ENST00000389397.4
VWA3A
von Willebrand factor A domain containing 3A
chr11_-_106889250 0.12 ENST00000526355.2
GUCY1A2
guanylate cyclase 1, soluble, alpha 2
chrX_+_122318006 0.12 ENST00000371266.1
ENST00000264357.5
GRIA3
glutamate receptor, ionotropic, AMPA 3
chr14_-_23877474 0.12 ENST00000405093.3
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr17_-_6947225 0.12 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
SLC16A11
solute carrier family 16, member 11
chr5_+_132009675 0.12 ENST00000231449.2
ENST00000350025.2
IL4
interleukin 4
chr7_-_102232891 0.12 ENST00000514917.2
RP11-514P8.7
RP11-514P8.7
chr11_+_62496114 0.11 ENST00000532583.1
TTC9C
tetratricopeptide repeat domain 9C
chr11_-_106889157 0.11 ENST00000282249.2
GUCY1A2
guanylate cyclase 1, soluble, alpha 2
chr16_+_28943260 0.11 ENST00000538922.1
ENST00000324662.3
ENST00000567541.1
CD19
CD19 molecule
chr16_+_57438679 0.11 ENST00000219244.4
CCL17
chemokine (C-C motif) ligand 17
chr12_-_72057638 0.11 ENST00000552037.1
ENST00000378743.3
ZFC3H1
zinc finger, C3H1-type containing
chr19_-_8642289 0.11 ENST00000596675.1
ENST00000338257.8
MYO1F
myosin IF
chr14_-_21567009 0.10 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219
zinc finger protein 219
chr5_-_132200477 0.10 ENST00000296875.2
GDF9
growth differentiation factor 9
chr5_+_82767284 0.10 ENST00000265077.3
VCAN
versican
chr19_+_10531150 0.10 ENST00000352831.6
PDE4A
phosphodiesterase 4A, cAMP-specific
chr2_-_114514181 0.10 ENST00000409342.1
SLC35F5
solute carrier family 35, member F5
chr5_+_148786518 0.10 ENST00000518014.1
ENST00000505340.1
ENST00000509909.1
AC131025.8
MIR143HG
AC131025.8
MIR143 host gene (non-protein coding)
chr4_+_84377198 0.10 ENST00000507349.1
ENST00000509970.1
ENST00000505719.1
MRPS18C
mitochondrial ribosomal protein S18C
chr12_-_57030115 0.09 ENST00000379441.3
ENST00000179765.5
ENST00000551812.1
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr1_-_54872059 0.09 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr19_-_18366182 0.09 ENST00000355502.3
PDE4C
phosphodiesterase 4C, cAMP-specific
chr22_-_36357671 0.08 ENST00000408983.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr3_-_47950745 0.08 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr18_-_24128496 0.08 ENST00000417602.1
KCTD1
potassium channel tetramerization domain containing 1
chr3_-_88108212 0.08 ENST00000482016.1
CGGBP1
CGG triplet repeat binding protein 1
chr1_+_3607228 0.08 ENST00000378285.1
ENST00000378280.1
ENST00000378288.4
TP73
tumor protein p73
chr10_-_102989551 0.07 ENST00000370193.2
LBX1
ladybird homeobox 1
chrX_-_13835147 0.07 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr3_+_101504200 0.07 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr9_-_23826298 0.07 ENST00000380117.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr8_+_37553261 0.07 ENST00000331569.4
ZNF703
zinc finger protein 703
chr6_-_44095183 0.06 ENST00000372014.3
MRPL14
mitochondrial ribosomal protein L14
chr6_-_132967142 0.06 ENST00000275216.1
TAAR1
trace amine associated receptor 1
chr6_+_30297306 0.06 ENST00000420746.1
ENST00000513556.1
TRIM39
TRIM39-RPP21
tripartite motif containing 39
TRIM39-RPP21 readthrough
chr17_+_47287749 0.06 ENST00000419580.2
ABI3
ABI family, member 3
chr17_+_4675175 0.06 ENST00000270560.3
TM4SF5
transmembrane 4 L six family member 5
chr12_+_104680659 0.06 ENST00000526691.1
ENST00000531691.1
ENST00000388854.3
ENST00000354940.6
ENST00000526390.1
ENST00000531689.1
TXNRD1
thioredoxin reductase 1
chr12_+_10124001 0.06 ENST00000396507.3
ENST00000304361.4
ENST00000434319.2
CLEC12A
C-type lectin domain family 12, member A
chr1_+_202091980 0.06 ENST00000367282.5
GPR37L1
G protein-coupled receptor 37 like 1
chrX_+_122318224 0.05 ENST00000542149.1
GRIA3
glutamate receptor, ionotropic, AMPA 3
chr3_+_112930306 0.05 ENST00000495514.1
BOC
BOC cell adhesion associated, oncogene regulated
chr5_-_39219705 0.05 ENST00000351578.6
FYB
FYN binding protein
chr2_-_26700900 0.05 ENST00000338581.6
ENST00000339598.3
ENST00000402415.3
OTOF
otoferlin
chr10_-_75415825 0.05 ENST00000394810.2
SYNPO2L
synaptopodin 2-like
chr6_+_29079668 0.04 ENST00000377169.1
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr8_-_131028869 0.04 ENST00000518283.1
ENST00000519110.1
FAM49B
family with sequence similarity 49, member B
chr14_+_50065376 0.04 ENST00000298288.6
LRR1
leucine rich repeat protein 1
chr13_-_36944307 0.04 ENST00000355182.4
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr2_-_128642434 0.04 ENST00000393001.1
AMMECR1L
AMMECR1-like
chr8_+_145294015 0.04 ENST00000544576.1
MROH1
maestro heat-like repeat family member 1
chr12_-_115121962 0.04 ENST00000349155.2
TBX3
T-box 3
chrX_+_122318318 0.04 ENST00000371251.1
ENST00000371256.5
GRIA3
glutamate receptor, ionotropic, AMPA 3
chr2_-_128784846 0.04 ENST00000259235.3
ENST00000357702.5
ENST00000424298.1
SAP130
Sin3A-associated protein, 130kDa
chr22_-_36236623 0.04 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_-_156460391 0.04 ENST00000360595.3
MEF2D
myocyte enhancer factor 2D
chr1_-_182641037 0.03 ENST00000483095.2
RGS8
regulator of G-protein signaling 8
chr4_+_159442878 0.03 ENST00000307765.5
ENST00000423548.1
RXFP1
relaxin/insulin-like family peptide receptor 1
chr2_-_190927447 0.03 ENST00000260950.4
MSTN
myostatin
chr12_-_72057571 0.03 ENST00000548100.1
ZFC3H1
zinc finger, C3H1-type containing
chr1_+_158323755 0.03 ENST00000368157.1
ENST00000368156.1
ENST00000368155.3
ENST00000368154.1
ENST00000368160.3
ENST00000368161.3
CD1E
CD1e molecule
chr12_-_54778471 0.03 ENST00000550120.1
ENST00000394313.2
ENST00000547210.1
ZNF385A
zinc finger protein 385A
chr1_+_36023035 0.03 ENST00000373253.3
NCDN
neurochondrin
chr17_+_55055466 0.03 ENST00000262288.3
ENST00000572710.1
ENST00000575395.1
SCPEP1
serine carboxypeptidase 1
chr1_-_182640988 0.03 ENST00000367556.1
RGS8
regulator of G-protein signaling 8
chr17_+_41150290 0.03 ENST00000589037.1
ENST00000253788.5
RPL27
ribosomal protein L27
chr5_-_156390230 0.02 ENST00000407087.3
ENST00000274532.2
TIMD4
T-cell immunoglobulin and mucin domain containing 4
chr19_-_45873642 0.02 ENST00000485403.2
ENST00000586856.1
ENST00000586131.1
ENST00000391940.4
ENST00000221481.6
ENST00000391944.3
ENST00000391945.4
ERCC2
excision repair cross-complementing rodent repair deficiency, complementation group 2
chr10_-_94003003 0.02 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.3 4.1 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.3 0.9 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.3 1.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 3.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.2 1.4 GO:0034436 glycoprotein transport(GO:0034436)
0.2 1.4 GO:2000391 positive regulation of neutrophil extravasation(GO:2000391)
0.2 1.6 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.2 0.7 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.2 0.5 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.2 1.5 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 0.5 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 0.7 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.3 GO:0021524 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913)
0.1 0.3 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.3 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.2 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.6 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.1 1.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.2 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.2 GO:0060738 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.3 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.3 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.4 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.1 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.1 GO:0071288 T-helper 1 cell lineage commitment(GO:0002296) B cell costimulation(GO:0031296) cellular response to mercury ion(GO:0071288) negative regulation of complement-dependent cytotoxicity(GO:1903660) positive regulation of eosinophil migration(GO:2000418)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.1 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.4 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 1.0 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.4 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.2 GO:2001138 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 1.4 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 3.0 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.0 GO:0060931 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.0 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.9 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.2 GO:0007512 adult heart development(GO:0007512)
0.0 0.0 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 1.0 GO:0044609 DBIRD complex(GO:0044609)
0.2 0.6 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.5 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 1.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.2 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 1.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.4 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.3 GO:0051286 cell tip(GO:0051286)
0.0 1.0 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.5 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.9 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.5 1.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.9 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 1.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.3 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 1.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.3 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.4 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 3.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 1.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME OPSINS Genes involved in Opsins
0.0 1.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation